OA12871A - Use of vasopeptidase inhibitors in the treatment of nephropathy. - Google Patents

Use of vasopeptidase inhibitors in the treatment of nephropathy. Download PDF

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Publication number
OA12871A
OA12871A OA1200400333A OA1200400333A OA12871A OA 12871 A OA12871 A OA 12871A OA 1200400333 A OA1200400333 A OA 1200400333A OA 1200400333 A OA1200400333 A OA 1200400333A OA 12871 A OA12871 A OA 12871A
Authority
OA
OAPI
Prior art keywords
compound
formula
diabetic
rats
use according
Prior art date
Application number
OA1200400333A
Other languages
English (en)
Inventor
Stefan Schaefer
Wolfgang Linz
Markus Bleich
Jochen Huber
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of OA12871A publication Critical patent/OA12871A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
OA1200400333A 2002-06-28 2003-06-13 Use of vasopeptidase inhibitors in the treatment of nephropathy. OA12871A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2002129180 DE10229180A1 (de) 2002-06-28 2002-06-28 Verwendung von Vasopeptidase-Inhibitoren bei der Behandlung von metabolischen Erkrankungen, Nephropathie und mit AGE assoziierten Erkrankungen

Publications (1)

Publication Number Publication Date
OA12871A true OA12871A (en) 2006-09-15

Family

ID=29795983

Family Applications (1)

Application Number Title Priority Date Filing Date
OA1200400333A OA12871A (en) 2002-06-28 2003-06-13 Use of vasopeptidase inhibitors in the treatment of nephropathy.

Country Status (38)

Country Link
US (2) US6930103B2 (sr)
EP (1) EP1519732B1 (sr)
JP (1) JP4564354B2 (sr)
KR (1) KR101072235B1 (sr)
CN (1) CN100366254C (sr)
AR (1) AR040343A1 (sr)
AT (1) ATE548040T1 (sr)
AU (1) AU2003280440B2 (sr)
BR (1) BR0312250A (sr)
CA (1) CA2490277C (sr)
CR (1) CR7667A (sr)
CY (1) CY1112905T1 (sr)
DE (1) DE10229180A1 (sr)
DK (1) DK1519732T3 (sr)
EC (1) ECSP045513A (sr)
ES (1) ES2383889T3 (sr)
HN (1) HN2003000193A (sr)
HR (1) HRP20041212B1 (sr)
IL (2) IL165935A0 (sr)
MA (1) MA27281A1 (sr)
MX (1) MXPA04012230A (sr)
NO (1) NO334811B1 (sr)
NZ (1) NZ537480A (sr)
OA (1) OA12871A (sr)
PA (1) PA8576501A1 (sr)
PE (1) PE20040582A1 (sr)
PL (1) PL218070B1 (sr)
PT (1) PT1519732E (sr)
RS (1) RS52478B (sr)
RU (1) RU2336080C2 (sr)
SI (1) SI1519732T1 (sr)
SV (1) SV2004001560A (sr)
TN (1) TNSN04262A1 (sr)
TW (1) TWI326215B (sr)
UA (1) UA82845C2 (sr)
UY (1) UY27869A1 (sr)
WO (1) WO2004002492A1 (sr)
ZA (1) ZA200409382B (sr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2482546C2 (ru) * 2011-04-28 2013-05-20 Общество С Ограниченной Ответственностью "Научно-Производственная Фирма "Материа Медика Холдинг" Способ коррекции эндотелиальной дисфункции раствором гомеопатических разведений антител к с-концевому фрагменту рецептора ангиотензина ii

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2053340C (en) * 1990-10-18 2002-04-02 Timothy P. Burkholder Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
US5430145A (en) * 1990-10-18 1995-07-04 Merrell Dow Pharmaceuticals Inc. Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
DK0589037T3 (da) * 1991-03-01 1996-09-16 Zeria Pharm Co Ltd Indanderivat og thromboxanantagonist indeholdende samme
RU2098411C1 (ru) * 1991-08-02 1997-12-10 Иституто Лусо Фармако д Италия С.п.А. Производные пиримидина, способ их получения, фармацевтическая композиция на их основе
DE69220744T2 (de) * 1991-09-27 1997-11-13 Merrell Pharma Inc 2-Substituierte Indan-2-Mercaptoacetylamid-Verbindungen mit Enkephalinase und ACE-Hemmwirkung
AU668707B2 (en) * 1992-02-14 1996-05-16 Merrell Pharmaceuticals Inc. Aminoacetylmercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ACE
US5484783A (en) * 1994-03-24 1996-01-16 Merrell Dow Pharmaceuticals Inc. Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide and benzazapine derivatives
ATE189392T1 (de) * 1994-03-24 2000-02-15 Merrell Pharma Inc Hypocholesterolemische, antiatherosklerotische und hypotriglyceridemische verwendung von aminoacetylmercapto derivaten
JPH11508894A (ja) * 1995-06-30 1999-08-03 メルク エンド カンパニー インコーポレーテッド Ace阻害剤とaii拮抗薬を用いる腎疾患の治療方法
CA2241856C (en) 1995-12-27 2006-10-17 Yoshitomi Pharmaceutical Industries Ltd. Agent for prophylaxis and treatment of diabetic complications
DK1216038T3 (da) * 1999-08-30 2005-12-27 Sanofi Aventis Deutschland Anvendelse af inhibitorer af reninangiotensinsystemet ved forebyggelsen af cardiovaskulære hændelser
US6149915A (en) 1999-09-29 2000-11-21 Shiva Biomedical, Llc Treatment of diabetic nephropathy and microalbuminuria
CN1245404C (zh) * 2001-04-12 2006-03-15 塞诺菲-安万特德国有限公司 巯基乙酰胺衍生物、其制备方法及其用途
WO2003013434A2 (en) * 2001-08-06 2003-02-20 Genomed, Llc Methods and compositions for treating diseases associated with excesses in ace

Also Published As

Publication number Publication date
RU2005102087A (ru) 2005-07-10
PT1519732E (pt) 2012-05-22
KR101072235B1 (ko) 2011-10-12
RU2336080C2 (ru) 2008-10-20
ECSP045513A (es) 2005-03-10
US20050171090A1 (en) 2005-08-04
KR20050013642A (ko) 2005-02-04
TWI326215B (en) 2010-06-21
AU2003280440B2 (en) 2009-07-16
AR040343A1 (es) 2005-03-30
TW200406214A (en) 2004-05-01
WO2004002492A1 (en) 2004-01-08
PL372992A1 (en) 2005-08-08
ES2383889T3 (es) 2012-06-27
US20040058911A1 (en) 2004-03-25
AU2003280440A1 (en) 2004-01-19
HRP20041212B1 (hr) 2013-06-30
CA2490277A1 (en) 2004-01-08
EP1519732B1 (en) 2012-03-07
IL165935A0 (en) 2006-01-15
ATE548040T1 (de) 2012-03-15
US6930103B2 (en) 2005-08-16
DK1519732T3 (da) 2012-06-18
HRP20041212A2 (en) 2005-06-30
SV2004001560A (es) 2004-02-26
PA8576501A1 (es) 2004-02-07
PE20040582A1 (es) 2004-10-18
CY1112905T1 (el) 2016-04-13
MXPA04012230A (es) 2005-02-25
HN2003000193A (es) 2004-10-27
CN1665512A (zh) 2005-09-07
RS52478B (sr) 2013-02-28
NO20050425L (no) 2005-01-25
BR0312250A (pt) 2005-04-26
DE10229180A1 (de) 2004-01-29
UY27869A1 (es) 2003-12-31
JP4564354B2 (ja) 2010-10-20
TNSN04262A1 (en) 2007-03-12
US7514423B2 (en) 2009-04-07
MA27281A1 (fr) 2005-04-01
JP2005533815A (ja) 2005-11-10
CN100366254C (zh) 2008-02-06
NO334811B1 (no) 2014-06-02
CR7667A (es) 2005-06-16
PL218070B1 (pl) 2014-10-31
ZA200409382B (en) 2006-01-25
HK1079435A1 (zh) 2006-04-07
UA82845C2 (en) 2008-05-26
RS100704A (sr) 2007-02-05
NZ537480A (en) 2005-11-25
CA2490277C (en) 2011-11-01
SI1519732T1 (sl) 2012-05-31
IL165935A (en) 2010-12-30
EP1519732A1 (en) 2005-04-06

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