OA13190A - Emulsifying systems containing azetidine derivatives. - Google Patents

Emulsifying systems containing azetidine derivatives. Download PDF

Info

Publication number: OA13190A
Authority: OA; OAPI
Prior art keywords: composition; azetidine; active ingredient; azetidine derivative; pharmaceutical composition
Prior art date: 2003-07-18

Application number

OA1200600017A

Other languages

English (en)

Inventor

Sophie Cote

Maria-Teresa Peracchia

Valerie Bobineau

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-07-18

Filing date

2004-07-08

Publication date

2006-12-13

2004-07-08 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2006-12-13 Publication of OA13190A publication Critical patent/OA13190A/en

Links

150000001539 azetidines Chemical class 0.000 title claims abstract description 42
230000001804 emulsifying effect Effects 0.000 title abstract description 5
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238000009472 formulation Methods 0.000 claims abstract description 43
239000000546 pharmaceutical excipient Substances 0.000 claims description 30
239000004480 active ingredient Substances 0.000 claims description 20
230000000694 effects Effects 0.000 claims description 20
230000003389 potentiating effect Effects 0.000 claims description 14
239000008389 polyethoxylated castor oil Substances 0.000 claims description 12
239000008194 pharmaceutical composition Substances 0.000 claims description 11
239000003795 chemical substances by application Substances 0.000 claims description 10
150000003904 phospholipids Chemical class 0.000 claims description 8
239000000654 additive Substances 0.000 claims description 6
238000010438 heat treatment Methods 0.000 claims description 6
UNAANXDKBXWMLN-UHFFFAOYSA-N sibutramine Chemical compound C=1C=C(Cl)C=CC=1C1(C(N(C)C)CC(C)C)CCC1 UNAANXDKBXWMLN-UHFFFAOYSA-N 0.000 claims description 5
229960004425 sibutramine Drugs 0.000 claims description 5
239000007787 solid Substances 0.000 claims description 5
HONIICLYMWZJFZ-UHFFFAOYSA-N azetidine Chemical compound C1CNC1 HONIICLYMWZJFZ-UHFFFAOYSA-N 0.000 claims description 4
210000004556 brain Anatomy 0.000 claims description 4
230000015883 synaptic transmission, dopaminergic Effects 0.000 claims description 4
125000003118 aryl group Chemical group 0.000 claims description 3
125000004567 azetidin-3-yl group Chemical group N1CC(C1)* 0.000 claims description 3
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HNQIVZYLYMDVSB-UHFFFAOYSA-N methanesulfonimidic acid Chemical compound CS(N)(=O)=O HNQIVZYLYMDVSB-UHFFFAOYSA-N 0.000 claims description 2
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239000001923 methylcellulose Substances 0.000 description 1
238000012986 modification Methods 0.000 description 1
230000004048 modification Effects 0.000 description 1
239000002159 nanocrystal Substances 0.000 description 1
125000001624 naphthyl group Chemical group 0.000 description 1
239000000346 nonvolatile oil Substances 0.000 description 1
229940100688 oral solution Drugs 0.000 description 1
125000002971 oxazolyl group Chemical group 0.000 description 1
239000002245 particle Substances 0.000 description 1
JLFNLZLINWHATN-UHFFFAOYSA-N pentaethylene glycol Chemical compound OCCOCCOCCOCCOCCO JLFNLZLINWHATN-UHFFFAOYSA-N 0.000 description 1
238000005191 phase separation Methods 0.000 description 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
230000004962 physiological condition Effects 0.000 description 1
229940113116 polyethylene glycol 1000 Drugs 0.000 description 1
235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
229920000053 polysorbate 80 Polymers 0.000 description 1
239000011591 potassium Substances 0.000 description 1
229910052700 potassium Inorganic materials 0.000 description 1
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FASDKYOPVNHBLU-ZETCQYMHSA-N pramipexole Chemical compound C1[C@@H](NCCC)CCC2=C1SC(N)=N2 FASDKYOPVNHBLU-ZETCQYMHSA-N 0.000 description 1
230000008569 process Effects 0.000 description 1
239000000770 propane-1,2-diol alginate Substances 0.000 description 1
235000010409 propane-1,2-diol alginate Nutrition 0.000 description 1
239000000473 propyl gallate Substances 0.000 description 1
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229940075579 propyl gallate Drugs 0.000 description 1
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UHSKFQJFRQCDBE-UHFFFAOYSA-N ropinirole Chemical compound CCCN(CCC)CCC1=CC=CC2=C1CC(=O)N2 UHSKFQJFRQCDBE-UHFFFAOYSA-N 0.000 description 1
229960003179 rotigotine Drugs 0.000 description 1
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235000010413 sodium alginate Nutrition 0.000 description 1
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229940001584 sodium metabisulfite Drugs 0.000 description 1
235000010262 sodium metabisulphite Nutrition 0.000 description 1
238000007711 solidification Methods 0.000 description 1
230000008023 solidification Effects 0.000 description 1
239000002904 solvent Substances 0.000 description 1
239000008347 soybean phospholipid Substances 0.000 description 1
KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
RKZSNTNMEFVBDT-MRVPVSSYSA-N sumanirole Chemical compound C([C@H](C1)NC)C2=CC=CC3=C2N1C(=O)N3 RKZSNTNMEFVBDT-MRVPVSSYSA-N 0.000 description 1
239000000829 suppository Substances 0.000 description 1
230000002195 synergetic effect Effects 0.000 description 1
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VUYXVWGKCKTUMF-UHFFFAOYSA-N tetratriacontaethylene glycol monomethyl ether Chemical compound COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO VUYXVWGKCKTUMF-UHFFFAOYSA-N 0.000 description 1
238000002560 therapeutic procedure Methods 0.000 description 1
125000000335 thiazolyl group Chemical group 0.000 description 1
125000001544 thienyl group Chemical group 0.000 description 1
229960000984 tocofersolan Drugs 0.000 description 1
AOBORMOPSGHCAX-DGHZZKTQSA-N tocofersolan Chemical compound OCCOC(=O)CCC(=O)OC1=C(C)C(C)=C2O[C@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C AOBORMOPSGHCAX-DGHZZKTQSA-N 0.000 description 1
VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 description 1
229940045145 uridine Drugs 0.000 description 1
MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 1
235000012141 vanillin Nutrition 0.000 description 1
230000000007 visual effect Effects 0.000 description 1
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239000011782 vitamin Substances 0.000 description 1
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235000013343 vitamin Nutrition 0.000 description 1
235000019165 vitamin E Nutrition 0.000 description 1
239000011709 vitamin E Substances 0.000 description 1
229940046009 vitamin E Drugs 0.000 description 1
150000003722 vitamin derivatives Chemical class 0.000 description 1
230000008673 vomiting Effects 0.000 description 1
239000002076 α-tocopherol Substances 0.000 description 1
235000004835 α-tocopherol Nutrition 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Obesity (AREA)
Hematology (AREA)
Psychology (AREA)
Psychiatry (AREA)
Diabetes (AREA)
Child & Adolescent Psychology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Inorganic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

OA1200600017A 2003-07-18 2004-07-08 Emulsifying systems containing azetidine derivatives. OA13190A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP03291797A EP1498123A1 (en)	2003-07-18	2003-07-18	Emulsifying systems containing azetidine derivatives

Publications (1)

Publication Number	Publication Date
OA13190A true OA13190A (en)	2006-12-13

Family

ID=33462260

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA1200600017A OA13190A (en)	2003-07-18	2004-07-08	Emulsifying systems containing azetidine derivatives.

Country Status (31)

Country	Link
US (1)	US20050037062A1 (es)
EP (2)	EP1498123A1 (es)
JP (1)	JP2009513559A (es)
KR (1)	KR20060040690A (es)
CN (1)	CN1822830A (es)
AR (1)	AR045912A1 (es)
AU (1)	AU2004262497A1 (es)
BR (1)	BRPI0412239A (es)
CA (1)	CA2532668A1 (es)
CR (1)	CR8178A (es)
EC (1)	ECSP066291A (es)
GT (1)	GT200400134A (es)
HR (1)	HRP20060021A2 (es)
IL (1)	IL173113A0 (es)
MA (1)	MA27921A1 (es)
MX (1)	MXPA06000478A (es)
MY (1)	MY142076A (es)
NO (1)	NO20060510L (es)
NZ (1)	NZ544707A (es)
OA (1)	OA13190A (es)
PA (1)	PA8606601A1 (es)
PE (1)	PE20050699A1 (es)
RS (1)	RS20050971A (es)
RU (1)	RU2348615C2 (es)
SG (1)	SG144140A1 (es)
TN (1)	TNSN06012A1 (es)
TW (1)	TW200522946A (es)
UA (1)	UA82539C2 (es)
UY (1)	UY28422A1 (es)
WO (1)	WO2005013972A1 (es)
ZA (1)	ZA200600489B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1498122A1 (en) *	2003-07-18	2005-01-19	Aventis Pharma S.A.	Semi-solid systems containing azetidine derivatives
US20070104780A1 (en) *	2005-10-25	2007-05-10	Lipari John M	Formulation comprising a drug of low water solubility and method of use thereof
KR20160003890A (ko) *	2006-09-29	2016-01-11	플루로메드, 인코포레이티드	쇄석술 동안 결석 및 단편 역류를 방지하는 방법
KR101493546B1 (ko) *	2007-08-21	2015-02-16	바실리어 파마슈티카 아게	항균 조성물
FR2923719B1 (fr) *	2007-11-15	2009-11-20	Sanofi Aventis	Compositions pharmaceutiques a base de derives d'azetidine
IT1394400B1 (it) *	2009-02-25	2012-06-15	Neuroscienze Pharmaness S C Ar L	Composizioni farmaceutiche
US10799479B2 (en)	2015-04-10	2020-10-13	Bioresponse, L.L.C.	Self-emulsifying formulations of DIM-related indoles
CN106551902B (zh) *	2015-09-17	2020-07-03	阿赖耶识（上海）生物技术有限公司	一种高稳定的非囊泡型纳米颗粒及其在治疗微生物感染中的应用
RU2019138507A (ru)	2017-05-02	2021-06-02	Мерк Шарп И Доум Корп.	Составы антител против lag3 и совместные составы антител против lag3 и антител против pd-1
JOP20190260A1 (ar)	2017-05-02	2019-10-31	Merck Sharp & Dohme	صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
US20240277615A1 (en) *	2021-06-11	2024-08-22	Universidade Da Beira Interior	Self-emulsifying composition, production methods and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9405304D0 (en) *	1994-03-16	1994-04-27	Scherer Ltd R P	Delivery systems for hydrophobic drugs
JP2740153B2 (ja) *	1995-03-07	1998-04-15	エフ・ホフマン−ラロシユアーゲー	混合ミセル
GB9600235D0 (en) *	1996-01-05	1996-03-06	Pfizer Ltd	Therapeutic agents
US6355631B1 (en) *	2000-03-03	2002-03-12	Aventis Pharma S.A.	Pharmaceutical compositions containing azetidine derivatives, novel azetidine derivatives and their preparation
FR2814678B1 (fr) *	2000-10-04	2002-12-20	Aventis Pharma Sa	Association d'un antagoniste du recepteur cb1 et de sibutramine, les compositions pharmaceutiques les contenant et leur utilisation pour la traitement de l'obesite
FR2829027A1 (fr) *	2001-08-29	2003-03-07	Aventis Pharma Sa	Association avec un antagoniste du recepteur cb1, les compositions pharmaceutiques les contenant et leur utilisation pour le traitement de la maladie de parkinson
FR2833842B1 (fr) *	2001-12-21	2004-02-13	Aventis Pharma Sa	Compositions pharmaceutiques a base de derives d'azetidine

2003
- 2003-07-18 EP EP03291797A patent/EP1498123A1/en not_active Withdrawn
2004
- 2004-07-01 PE PE2004000633A patent/PE20050699A1/es not_active Application Discontinuation
- 2004-07-08 OA OA1200600017A patent/OA13190A/en unknown
- 2004-07-08 RU RU2006105000/04A patent/RU2348615C2/ru not_active IP Right Cessation
- 2004-07-08 MX MXPA06000478A patent/MXPA06000478A/es not_active Application Discontinuation
- 2004-07-08 CN CNA2004800206437A patent/CN1822830A/zh active Pending
- 2004-07-08 KR KR1020067001146A patent/KR20060040690A/ko not_active Withdrawn
- 2004-07-08 JP JP2006519900A patent/JP2009513559A/ja active Pending
- 2004-07-08 CA CA002532668A patent/CA2532668A1/en not_active Abandoned
- 2004-07-08 SG SG200804302-8A patent/SG144140A1/en unknown
- 2004-07-08 BR BRPI0412239-9A patent/BRPI0412239A/pt not_active IP Right Cessation
- 2004-07-08 HR HR20060021A patent/HRP20060021A2/hr not_active Application Discontinuation
- 2004-07-08 RS YUP-2005/0971A patent/RS20050971A/sr unknown
- 2004-07-08 AU AU2004262497A patent/AU2004262497A1/en not_active Abandoned
- 2004-07-08 NZ NZ544707A patent/NZ544707A/en unknown
- 2004-07-08 EP EP04741332A patent/EP1648441A1/en not_active Withdrawn
- 2004-07-08 WO PCT/EP2004/008552 patent/WO2005013972A1/en not_active Ceased
- 2004-07-13 US US10/889,729 patent/US20050037062A1/en not_active Abandoned
- 2004-07-14 PA PA20048606601A patent/PA8606601A1/es unknown
- 2004-07-15 AR ARP040102494A patent/AR045912A1/es not_active Application Discontinuation
- 2004-07-16 GT GT200400134A patent/GT200400134A/es unknown
- 2004-07-16 MY MYPI20042870A patent/MY142076A/en unknown
- 2004-07-16 TW TW093121230A patent/TW200522946A/zh unknown
- 2004-07-16 UY UY28422A patent/UY28422A1/es unknown
- 2004-08-07 UA UAA200601706A patent/UA82539C2/uk unknown
2006
- 2006-01-06 CR CR8178A patent/CR8178A/es not_active Application Discontinuation
- 2006-01-12 IL IL173113A patent/IL173113A0/en unknown
- 2006-01-16 MA MA28725A patent/MA27921A1/fr unknown
- 2006-01-17 ZA ZA200600489A patent/ZA200600489B/xx unknown
- 2006-01-17 EC EC2006006291A patent/ECSP066291A/es unknown
- 2006-01-17 TN TNP2006000012A patent/TNSN06012A1/en unknown
- 2006-01-31 NO NO20060510A patent/NO20060510L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
SG144140A1 (en)	2008-07-29
RU2006105000A (ru)	2006-07-10
IL173113A0 (en)	2006-06-11
ECSP066291A (es)	2006-07-28
ZA200600489B (en)	2007-04-25
MXPA06000478A (es)	2006-04-05
NO20060510L (no)	2006-01-31
RS20050971A (sr)	2008-06-05
CR8178A (es)	2007-12-04
EP1648441A1 (en)	2006-04-26
KR20060040690A (ko)	2006-05-10
JP2009513559A (ja)	2009-04-02
AU2004262497A2 (en)	2005-02-17
UA82539C2 (en)	2008-04-25
MY142076A (en)	2010-08-30
CA2532668A1 (en)	2005-02-17
US20050037062A1 (en)	2005-02-17
WO2005013972A1 (en)	2005-02-17
TW200522946A (en)	2005-07-16
MA27921A1 (fr)	2006-06-01
RU2348615C2 (ru)	2009-03-10
TNSN06012A1 (en)	2007-10-03
PE20050699A1 (es)	2005-09-15
PA8606601A1 (es)	2005-03-03
GT200400134A (es)	2005-02-22
HRP20060021A2 (en)	2006-02-28
AU2004262497A1 (en)	2005-02-17
CN1822830A (zh)	2006-08-23
BRPI0412239A (pt)	2006-09-12
UY28422A1 (es)	2005-02-28
NZ544707A (en)	2009-01-31
EP1498123A1 (en)	2005-01-19
AR045912A1 (es)	2005-11-16

Publication	Publication Date	Title
US20110053903A1 (en)	2011-03-03	Pharmaceutical compositions based on azetidine derivatives
AU2002364866B2 (en)	2006-11-30	Pharmaceutical compositions based on azetidine derivatives
EP1498123A1 (en)	2005-01-19	Emulsifying systems containing azetidine derivatives
US20080293686A1 (en)	2008-11-27	Semi-solid systems containing azetidine derivatives
HK1070840B (en)	2008-11-28	Pharmaceutical compositions based on azetidine derivatives
HK1089953A (en)	2006-12-15	Semi-solid systems containing azetidine derivatives