PE20021099A1 - Derivados de c-furano-2-il-metilamina sustituidos - Google Patents

Derivados de c-furano-2-il-metilamina sustituidos

Info

Publication number: PE20021099A1
Authority: PE; Peru
Prior art keywords: ethyl; phenylamine; aryl; alkyl; methyl
Prior art date: 2001-05-22

Application number

PE2002000428A

Other languages

English (en)

Spanish (es)

Inventor

Corinna Maul

Michael Przewosny

Original Assignee

Gruenenthal Chemie

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-22

Filing date

2002-05-21

Publication date

2003-01-25

2002-05-21 Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie

2003-01-25 Publication of PE20021099A1 publication Critical patent/PE20021099A1/es

Links

150000001875 compounds Chemical class 0.000 abstract 2
AKCRQHGQIJBRMN-UHFFFAOYSA-N 2-chloroaniline Chemical compound NC1=CC=CC=C1Cl AKCRQHGQIJBRMN-UHFFFAOYSA-N 0.000 abstract 1
KMYNSRFDYFGKLR-UHFFFAOYSA-N 4-chloro-2-ethyl-N-methylaniline Chemical compound CCC1=CC(Cl)=CC=C1NC KMYNSRFDYFGKLR-UHFFFAOYSA-N 0.000 abstract 1
-1 N- (CYCLOPROPYL-2-THENYLMEthyl) -4,5-DIHYDRO-2-OXAZOLAMINE Chemical compound 0.000 abstract 1
229940035676 analgesics Drugs 0.000 abstract 1
229940035674 anesthetics Drugs 0.000 abstract 1
239000000730 antalgic agent Substances 0.000 abstract 1
230000003288 anthiarrhythmic effect Effects 0.000 abstract 1
239000003416 antiarrhythmic agent Substances 0.000 abstract 1
239000003193 general anesthetic agent Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Anesthesiology (AREA)
Dermatology (AREA)
Urology & Nephrology (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Furan Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Plural Heterocyclic Compounds (AREA)

PE2002000428A 2001-05-22 2002-05-21 Derivados de c-furano-2-il-metilamina sustituidos PE20021099A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE10125145A DE10125145A1 (de)	2001-05-22	2001-05-22	Substituierte C-Furan-2-yl-methylamin- und C-Thiophen-2-yl-methylamin-Derivate

Publications (1)

Publication Number	Publication Date
PE20021099A1 true PE20021099A1 (es)	2003-01-25

Family

ID=7685874

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PE2002000428A PE20021099A1 (es)	2001-05-22	2002-05-21	Derivados de c-furano-2-il-metilamina sustituidos

Country Status (17)

Country	Link
US (2)	US6878740B2 (pl)
EP (1)	EP1392670B1 (pl)
JP (1)	JP2004532246A (pl)
AR (1)	AR035982A1 (pl)
AT (1)	ATE299873T1 (pl)
AU (1)	AU2002338989B2 (pl)
CA (1)	CA2448038C (pl)
DE (2)	DE10125145A1 (pl)
DK (1)	DK1392670T3 (pl)
ES (1)	ES2242869T3 (pl)
HU (1)	HUP0401162A3 (pl)
MX (1)	MXPA03010601A (pl)
PE (1)	PE20021099A1 (pl)
PL (1)	PL367535A1 (pl)
PT (1)	PT1392670E (pl)
SI (1)	SI1392670T1 (pl)
WO (1)	WO2002094802A1 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0302094D0 (en) *	2003-01-29	2003-02-26	Pharmagene Lab Ltd	EP4 receptor antagonists
GB0324269D0 (en) *	2003-10-16	2003-11-19	Pharmagene Lab Ltd	EP4 receptor antagonists
KR100553398B1 (ko)	2004-03-12	2006-02-16	한미약품 주식회사	티에노[3,2-ｃ]피리딘 유도체의 제조 방법 및 이에사용되는 중간체
SG176983A1 (en)	2009-07-08	2012-02-28	Dermira Canada Inc	Tofa analogs useful in treating dermatological disorders or conditions
PL2897589T3 (pl) *	2013-11-22	2018-06-29	Teva Branded Pharmaceutical Products R & D, Inc.	Lek do inhalacji
CN109153659A (zh) *	2016-05-31	2019-01-04	翰林大学产学研合作团队	五元杂环衍生物、其制备方法及包含其的药剂学组合物
CN112521357B (zh) *	2020-08-31	2021-10-08	深圳瑞健生物科技有限公司	一种长效低成瘾性hnk衍生物及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3816457A (en) *	1973-01-05	1974-06-11	Richardson Merrell Inc	Lactamimide derivatives
US3890445A (en) *	1973-01-05	1975-06-17	Richardson Merrell Inc	Lactamimide derivatives useful as hypoglycemic agents
WO2001068816A1 (en)	2000-03-13	2001-09-20	Smithkline Beecham Corporation	Human histamine h3 gene variant-3
DE10012820A1 (de) *	2000-03-16	2001-09-20	Bayer Ag	Substituierte 1-Aryl-cyclopropylmethylamino-1,3,5-triazine
DE10059864A1 (de) *	2000-11-30	2002-06-13	Gruenenthal Gmbh	Substituierte Amino-furan-2-yl-essigsäure- und Amino-thien-2-yl-essigsäure-Derivate

2001
- 2001-05-22 DE DE10125145A patent/DE10125145A1/de not_active Withdrawn
2002
- 2002-05-17 AR ARP020101843A patent/AR035982A1/es not_active Application Discontinuation
- 2002-05-21 PE PE2002000428A patent/PE20021099A1/es not_active Application Discontinuation
- 2002-05-21 MX MXPA03010601A patent/MXPA03010601A/es active IP Right Grant
- 2002-05-21 DK DK02743057T patent/DK1392670T3/da active
- 2002-05-21 WO PCT/EP2002/005542 patent/WO2002094802A1/de not_active Ceased
- 2002-05-21 JP JP2002591475A patent/JP2004532246A/ja active Pending
- 2002-05-21 HU HU0401162A patent/HUP0401162A3/hu unknown
- 2002-05-21 PT PT02743057T patent/PT1392670E/pt unknown
- 2002-05-21 PL PL02367535A patent/PL367535A1/pl not_active Application Discontinuation
- 2002-05-21 AT AT02743057T patent/ATE299873T1/de not_active IP Right Cessation
- 2002-05-21 ES ES02743057T patent/ES2242869T3/es not_active Expired - Lifetime
- 2002-05-21 EP EP02743057A patent/EP1392670B1/de not_active Expired - Lifetime
- 2002-05-21 CA CA2448038A patent/CA2448038C/en not_active Expired - Fee Related
- 2002-05-21 DE DE50203686T patent/DE50203686D1/de not_active Expired - Lifetime
- 2002-05-21 AU AU2002338989A patent/AU2002338989B2/en not_active Ceased
- 2002-05-21 SI SI200230178T patent/SI1392670T1/sl unknown
2003
- 2003-11-21 US US10/717,932 patent/US6878740B2/en not_active Expired - Fee Related
2005
- 2005-03-07 US US11/072,962 patent/US7317034B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP2004532246A (ja)	2004-10-21
US20050148550A1 (en)	2005-07-07
US6878740B2 (en)	2005-04-12
HUP0401162A3 (en)	2007-05-02
US20040152734A1 (en)	2004-08-05
WO2002094802A1 (de)	2002-11-28
AR035982A1 (es)	2004-07-28
HUP0401162A2 (hu)	2004-10-28
EP1392670B1 (de)	2005-07-20
DK1392670T3 (da)	2005-08-08
CA2448038A1 (en)	2002-11-28
ATE299873T1 (de)	2005-08-15
DE10125145A1 (de)	2002-11-28
EP1392670A1 (de)	2004-03-03
PT1392670E (pt)	2005-10-31
AU2002338989B2 (en)	2007-06-07
PL367535A1 (pl)	2005-02-21
DE50203686D1 (en)	2005-08-25
SI1392670T1 (sl)	2005-12-31
US7317034B2 (en)	2008-01-08
ES2242869T3 (es)	2005-11-16
CA2448038C (en)	2010-09-28
MXPA03010601A (es)	2004-03-09

Legal Events

Date	Code	Title	Description
2006-07-13	FG	Grant, registration
2006-12-15	FD	Application declared void or lapsed

Publication	Publication Date	Title
DK0666858T3 (da)	2001-08-27	5-arylindolderivater og deres anvendelse som serotonin(5-HT1)-agonister
MX9706382A (es)	1997-11-29	Derivados de benzoilo.
DE69902634D1 (de)	2002-10-02	Substituierte aminophenylisoxazolinderivate verwendbar als antimikrobielle agenzien
ATE282614T1 (de)	2004-12-15	Phenylharnstoff und phenylthioharnstoffderivate
PE20030062A1 (es)	2003-02-08	Derivados aralquilsulfonil-3-(pirrol-2-ilmetiliden)-2-indolinona como inhibidores de quinasas
ATE292628T1 (de)	2005-04-15	Chinazolinderivate
ATE323717T1 (de)	2006-05-15	Piperazin-4-phenyl-derivate als inhibitoren der wechselwirkung zwischen mdm2 und mdm2
CY1105863T1 (el)	2011-02-02	Παραγωγα εποθιλονης και η συνθεση και η χρηση τους
DK1046391T3 (da)	2004-10-18	Anvendelse af aminosubstituerede hydroxybenzophenoner som fotostabile UV-filtre i kosmetiske og farmaceutiske præparater
BR0013237A (pt)	2003-07-15	Fenil oxazolidinonas substituìdas heterobiciclicas antibacterianas
HRP20090071T3 (en)	2009-04-30	Indole derivatives and use thereof as kinase inhibitors in particular ikk2 inhibitors
DE69835460D1 (de)	2006-09-14	Indolecarbonsäurederivate und ihre Verwendung als Arzneimittel
DE69522703D1 (de)	2001-10-18	Aminotetrazol-derivate verwendbar als stickstoff-oxid-synthase inhibitoren
NO20052976L (no)	2005-08-18	Fosfodiesterase-4-inhibitorer.
ATE359073T1 (de)	2007-05-15	Benzylidenthiazolidindione und ihre verwendung als antimykotische mittel
ES2180201T3 (es)	2003-02-01	Derivados de azetidinona para el tratamiento de infecciones por hcmv.
PE20040750A1 (es)	2004-11-06	Derivados de n-(1-acetilpiperidin-4-il)-4-benzidril-2-isopropilpiperazin-1-carboxamida como inhibidores de 17beta-hidroxiesteroide deshidrogenasa de tipo 3
ATE233242T1 (de)	2003-03-15	Chinoline und chinazoline verbindungen und ihre therapeutische anwendung
HRP20070286T3 (en)	2007-08-31	Substituted diketopiperazines and their use as oxytocyn antagonists
BR0208823A (pt)	2004-03-09	Composto, método de tratamento de distúrbios que são remediados ou aliviados pela atividade de agonista de vasopressina em um mamìfero necessitando do mesmo, e, composição farmacêutica
DK0612314T3 (da)	2000-05-29	2-pyrazinylethylaminderivater og deres anvendelse som lægemidler
ES2102327A1 (es)	1997-07-16	Nuevos derivados de 2,2,6,6-tetrametilpiperidina para utilizarse como agentes estabilizantes para materiales organicos contra la luz, el calor, y la oxidacion. n
AR027035A1 (es)	2003-03-12	Pirroles sustituidos
NZ335975A (en)	2000-11-24	Heterocyclic substituted pyrrolidine amide derivatives useful in treating respiratory diseases
DE60142507D1 (de)	2010-08-19	Trh-ähnliche peptidderivate als inhibitoren des trh-abbauenden ektoenzyms