PE20141185A1 - Yoduro de povidona, un nuevo conservante alternativo para composiciones oftalmicas - Google Patents

Yoduro de povidona, un nuevo conservante alternativo para composiciones oftalmicas

Info

Publication number
PE20141185A1
PE20141185A1 PE2013002829A PE2013002829A PE20141185A1 PE 20141185 A1 PE20141185 A1 PE 20141185A1 PE 2013002829 A PE2013002829 A PE 2013002829A PE 2013002829 A PE2013002829 A PE 2013002829A PE 20141185 A1 PE20141185 A1 PE 20141185A1
Authority
PE
Peru
Prior art keywords
ophthalmic compositions
new alternative
povidone iodide
alternative preservative
influentic
Prior art date
Application number
PE2013002829A
Other languages
English (en)
Inventor
Joseph A Capriotti
Bo Liang
C Michael Samson
Jason Stein
Michael Weiser
Original Assignee
Foresigth Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41417019&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20141185(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Foresigth Biotherapeutics Inc filed Critical Foresigth Biotherapeutics Inc
Publication of PE20141185A1 publication Critical patent/PE20141185A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79—Polymers of vinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/10—Halogens or compounds thereof
    • A61L12/105—Iodine, iodides or iodophores
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE REFIERE A UNA PREPARACION OFTALMICA CONSERVADA QUE COMPRENDE: A) YODURO DE POVIDONA (PVP-I) EN UNA CONCENTRACION SUFICIENTE PARA CONSERVAR DICHA PREPARACION OFTALMICA, B) UN MIEMBRO SELECCIONADO DEL GRUPO QUE CONSISTE DE UN COMPUESTO ANTIINFLAMATORIO ESTEROIDE, UN COMPUESTO ANTIBACTERIAL, UN COMPUESTO ANTIALERGICO, ENTRE OTROS, C) UN AGENTE VISCOSANTE, D) UN LUBRICANTE. DICHA PREPARACION AL CONTENER PVP-I PRESENTA MENOR POTENCIAL DE TOXICIDAD QUE OTRAS PREPARACIONES SIMILARES.
PE2013002829A 2008-06-12 2009-06-10 Yoduro de povidona, un nuevo conservante alternativo para composiciones oftalmicas PE20141185A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12922208P 2008-06-12 2008-06-12
US20185408P 2008-12-15 2008-12-15

Publications (1)

Publication Number Publication Date
PE20141185A1 true PE20141185A1 (es) 2014-09-21

Family

ID=41417019

Family Applications (2)

Application Number Title Priority Date Filing Date
PE2013002829A PE20141185A1 (es) 2008-06-12 2009-06-10 Yoduro de povidona, un nuevo conservante alternativo para composiciones oftalmicas
PE2010001131A PE20110162A1 (es) 2008-06-12 2009-06-10 Yoduro de povidona, un nuevo conservante alternativo para composiciones oftalmicas

Family Applications After (1)

Application Number Title Priority Date Filing Date
PE2010001131A PE20110162A1 (es) 2008-06-12 2009-06-10 Yoduro de povidona, un nuevo conservante alternativo para composiciones oftalmicas

Country Status (20)

Country Link
US (2) US20120027716A1 (es)
EP (2) EP3777536A1 (es)
JP (4) JP2011522891A (es)
KR (3) KR20180014859A (es)
CN (3) CN105944105A (es)
AU (1) AU2009258145A1 (es)
BR (1) BRPI0913417B1 (es)
CA (2) CA2937997A1 (es)
CL (1) CL2010001406A1 (es)
CO (1) CO6341526A2 (es)
DK (1) DK2291081T3 (es)
EC (1) ECSP11010755A (es)
ES (1) ES2810863T3 (es)
HK (1) HK1202074A1 (es)
MX (3) MX372536B (es)
NZ (3) NZ625086A (es)
PE (2) PE20141185A1 (es)
PL (1) PL2291081T3 (es)
PT (1) PT2291081T (es)
WO (1) WO2009151619A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090263345A1 (en) * 2008-01-28 2009-10-22 Foresight Biotherapeutics, Inc. Otic compositions for the treatment of infections of the internal and external ear in mammals
AU2015252097A1 (en) * 2009-12-15 2015-11-19 Foresight Biotherapeutics, Inc. Non-irritating ophthalmic povidone-iodine compositions
TWI618539B (zh) * 2009-12-15 2018-03-21 遠景生物製藥股份有限公司 無刺激性眼用聚乙烯吡咯啶酮-碘組成物
CN103228283A (zh) * 2010-11-29 2013-07-31 千寿制药株式会社 含有二氟泼尼酯和托普霉素的水包油型乳状液组合物
BR112013018025A2 (pt) * 2011-01-18 2020-10-27 Senju Pharmaceutical Co., Ltd composição de bromfenac líquida aquosa método para reforçar a eficácia conservante de uma solução aquosa
KR101967938B1 (ko) * 2011-05-12 2019-04-10 포어사이트 바이오쎄라퓨틱스, 인코퍼레이티드 스테로이드 또는 비-스테로이드성 소염제를 갖는 안정한 포비돈-요오드 조성물
TW202023575A (zh) * 2011-09-16 2020-07-01 美商遠景生物製藥股份有限公司 安定之普維酮—碘組成物
JP6161500B2 (ja) * 2012-10-05 2017-07-12 ロート製薬株式会社 ブロムフェナク含有組成物
US9630909B2 (en) 2013-06-27 2017-04-25 Mylan Laboratories Ltd Process for the preparation of nepafenac
DE102014010694A1 (de) 2014-07-09 2016-01-28 Beuth Hochschule Für Technik Berlin Jod enthaltende pharmazeutische Zusammensetzung mit antimikrobiellen Eigenschaften sowie Verfahren zur Herstellung
JP6280675B1 (ja) * 2015-01-20 2018-02-14 ヴェローチェ・バイオファーマ・エルエルシー 新規ヨードフォア組成物および使用方法
ITUA20162425A1 (it) * 2016-04-08 2017-10-08 Medivis S R L Composizione oftalmica che comprende PVP-I
CN110114119B (zh) * 2016-10-12 2022-05-31 Ps治疗有限公司 人工泪液、隐形眼镜和药物载体组合物及其使用方法
JP6320616B1 (ja) * 2017-08-22 2018-05-09 ヴェローチェ・バイオファーマ・エルエルシー 新規眼科用組成物および使用方法
CA3145888A1 (en) * 2018-07-31 2020-02-06 Isilay KAVADARLI Ophthalmic formulations and uses thereof
KR20240134913A (ko) 2022-01-21 2024-09-10 센주 유에스에이, 인코포레이티드 수성 액제
WO2025027498A1 (en) * 2023-08-03 2025-02-06 Alcon Inc. Multidose preservative-free (mdpf) ophthalmic dose delivery with addition of formulation surfactants

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5414011A (en) * 1987-09-11 1995-05-09 Syntex (U.S.A.) Inc. Preservative system for ophthalmic formulations
CA1303503C (en) * 1987-11-10 1992-06-16 Marc Plamondon Ophthalmic solution comprising iodine-polyvinylpyrrolidone complex
EP0365613B1 (en) * 1988-03-09 1995-05-17 Alcon Laboratories, Inc. Combination of tobramycin and steroids for topical ophthalmic use
US5126127A (en) * 1991-07-16 1992-06-30 Euroceltique, S.A. Stabilized PVP-I solutions
US6328991B1 (en) * 1992-10-21 2001-12-11 John Myhling Composition and method for prevention of sexually transmitted diseases, including aids
JP2006519841A (ja) * 2003-03-10 2006-08-31 ザンテック ファーマスーティカルズ，インク． 改善された抗菌性能を有する表面消毒組成物
US20050095205A1 (en) * 2003-10-31 2005-05-05 Ramesh Krishnamoorthy Combination of loteprednol etabonate and tobramycin for topical ophthalmic use
US7829544B2 (en) * 2003-11-14 2010-11-09 Senju Pharmaceutical Co., Ltd. Aqueous solution preparation containing aminoglycoside antibiotic and bromfenac
US7767217B2 (en) * 2006-03-14 2010-08-03 Foresight Biotherapeutics Ophthalmic compositions comprising povidone-iodine
US20070297990A1 (en) * 2006-06-27 2007-12-27 Shah Mandar V Self-preserving composition

Also Published As

Publication number Publication date
CO6341526A2 (es) 2011-11-21
KR20160045153A (ko) 2016-04-26
US20130251666A1 (en) 2013-09-26
US20120027716A1 (en) 2012-02-02
JP2019052172A (ja) 2019-04-04
MX372536B (es) 2020-03-23
WO2009151619A1 (en) 2009-12-17
AU2009258145A1 (en) 2009-12-17
CN105944105A (zh) 2016-09-21
CA2727605A1 (en) 2009-12-17
BRPI0913417B1 (pt) 2021-06-08
HK1202074A1 (en) 2015-09-18
BRPI0913417A2 (pt) 2020-08-04
ECSP11010755A (es) 2011-07-29
CL2010001406A1 (es) 2011-07-08
CA2937997A1 (en) 2009-12-17
MX2020003159A (es) 2020-07-29
CA2727605C (en) 2016-10-04
JP2015129139A (ja) 2015-07-16
KR20180014859A (ko) 2018-02-09
CN102118973A (zh) 2011-07-06
NZ603346A (en) 2014-05-30
EP2291081A1 (en) 2011-03-09
NZ747878A (en) 2020-07-31
MX338674B (es) 2016-04-27
DK2291081T3 (da) 2020-08-10
EP3777536A1 (en) 2021-02-17
ES2810863T3 (es) 2021-03-09
MX2010013670A (es) 2011-06-24
NZ625086A (en) 2015-11-27
JP2011522891A (ja) 2011-08-04
JP2021035984A (ja) 2021-03-04
EP2291081B1 (en) 2020-06-03
PE20110162A1 (es) 2011-04-06
CN104189911A (zh) 2014-12-10
KR20110018414A (ko) 2011-02-23
JP6527341B2 (ja) 2019-06-05
PT2291081T (pt) 2020-09-10
EP2291081A4 (en) 2013-10-23
PL2291081T3 (pl) 2021-01-25

Similar Documents

Publication Publication Date Title
PE20141185A1 (es) Yoduro de povidona, un nuevo conservante alternativo para composiciones oftalmicas
CL2017000955A1 (es) Composición que comprende un agente de control biológico de la especie bacillus subtilis y un fungicida del grupo de inhibidores de la mitosis y la división celular, tal como clorotalonilo
BR112015019044A8 (pt) composição adesiva antimicrobiana, seu uso, seu artigo metódico, e método de aumentar a liberação de um agente antimicrobiano a partir de uma composição adesiva
AR080483A1 (es) Metodo para estabilizar dispersiones acuosas de compuestas bioactivos en agua
PE20180230A1 (es) Composicion hemostatica y dispositivo hemostatico (variantes)
CR20140539A (es) Preparación que contiene por lo menos un fungicida conazólico
MX2010002930A (es) Formulaciones que comprenden una composicion anti-microbiana.
MX2010010726A (es) Composicion de estilizado de cabello.
WO2012047762A3 (en) Antifungal agents
EA033311B1 (ru) Производные бензоксаборола в качестве антибактериальных средств
AR072248A1 (es) Formulacion acuosa estable que contiene esporas
AR062212A1 (es) Composicion y metodo en relacion con la prevencion y la solucion del dano del gel surfactante
CL2012000469A1 (es) Composición farmacéutica que comprende un compuesto conjugado de insulina de absorcion lenta; un envase; una suspensión que comprende la composición y su método de preparación; su uso para el tratamiento o prevención de una patología asociado a deficiencia de insulina, como diabetes; un kit.
BR112014000178A2 (pt) composições tópicas
WO2006135854A3 (en) Antiseptic compositions
AR093269A1 (es) Composiciones detergentes liquidas para la limpieza y desinfeccion de vajilla a mano
CL2011001306A1 (es) Composicion antimicrobiana que comprende una sal de plata soluble, una alcanolamida, y/o aminoalcohol, un ph 6 o superior; composicion limpiadora que comprende un surfactante, una sal de plata soluble, una alcanolamida, y/o aminoalcohol.
WO2011056545A3 (en) Antimicrobial ionic liquids
MX2010005013A (es) Composiciones intranasales.
CO6180423A2 (es) Forma farmaceutica que contiene metocarbamol, meloxicam y betametasona
DOP2014000252A (es) (R)-Nifuratel, su Uso para el Tratamiento de Infecciones y Síntesis de (R) y (S)-Nifuratel
DOP2006000268A (es) Agentes antibacterianos
BR112013019394A2 (pt) uso de um agente
HK1243951A1 (zh) 抗微生物组合和其在治疗微生物感染中的用途
MX387476B (es) Antibióticos de amplio espectro macrocíclico.

Legal Events

Date Code Title Description
FC Refusal