PE20170140A1 - Metodos para tratar el cancer con inhibidores de tigit y agentes contra el cancer - Google Patents

Metodos para tratar el cancer con inhibidores de tigit y agentes contra el cancer

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Publication number
PE20170140A1
PE20170140A1 PE2017000058A PE2017000058A PE20170140A1 PE 20170140 A1 PE20170140 A1 PE 20170140A1 PE 2017000058 A PE2017000058 A PE 2017000058A PE 2017000058 A PE2017000058 A PE 2017000058A PE 20170140 A1 PE20170140 A1 PE 20170140A1
Authority
PE
Peru
Prior art keywords
agent
cancer
tigit
seq
methods
Prior art date
Application number
PE2017000058A
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English (en)
Inventor
Jane L Grogan
Original Assignee
Genentech Inc
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Publication date
Family has litigation
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Application filed by Genentech Inc filed Critical Genentech Inc
Publication of PE20170140A1 publication Critical patent/PE20170140A1/es

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Abstract

La presente divulgacion provee metodos que comprenden la administracion al individuo de un agente que reduce o inhibe la actividad y/o la expresion de TIGIT tal como un anticuerpo anti-TIGIT que comprende al menos una HVR con una secuencia de aminoacidos SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, entre otros y un agente contra el cancer tal como un agente alquilante, un agente antihormonal, un inhibidor de aromatasa, entre otros. Tambien se proveen kits que comprenden un agente contra el cancer, un agente que reduce o inhibe la actividad y/o la expresion de TIGIT, o ambas, asi como instrucciones para su uso
PE2017000058A 2014-07-16 2015-07-16 Metodos para tratar el cancer con inhibidores de tigit y agentes contra el cancer PE20170140A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462025394P 2014-07-16 2014-07-16

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PE20170140A1 true PE20170140A1 (es) 2017-03-30

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PE2017000058A PE20170140A1 (es) 2014-07-16 2015-07-16 Metodos para tratar el cancer con inhibidores de tigit y agentes contra el cancer

Country Status (19)

Country Link
US (9) US20170143825A1 (es)
EP (1) EP3169363A4 (es)
JP (4) JP2017522311A (es)
KR (1) KR20170023081A (es)
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