PH12012502181A1 - A biocompatible, non-biodegradable, non-toxic polymer useful for nanoparticle pharmaceutical compositions - Google Patents

A biocompatible, non-biodegradable, non-toxic polymer useful for nanoparticle pharmaceutical compositions

Info

Publication number
PH12012502181A1
PH12012502181A1 PH1/2012/502181A PH12012502181A PH12012502181A1 PH 12012502181 A1 PH12012502181 A1 PH 12012502181A1 PH 12012502181 A PH12012502181 A PH 12012502181A PH 12012502181 A1 PH12012502181 A1 PH 12012502181A1
Authority
PH
Philippines
Prior art keywords
pharmaceutical compositions
toxic
biocompatible
biodegradable
relates
Prior art date
Application number
PH1/2012/502181A
Other languages
English (en)
Inventor
C Burman Anand
Prusthy Deepak
Khattar Dhiraj
Kumar Singh Manoj
Jaggi Manu
Kumar Mukesh
Kumar Gupta Pawan
Praveen Rajendran
Mukherjee Rama
Mullick Sanjoy
Singh Shobhit
Original Assignee
Fresenius Kabi Oncology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Kabi Oncology Ltd filed Critical Fresenius Kabi Oncology Ltd
Publication of PH12012502181A1 publication Critical patent/PH12012502181A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52Amides or imides
    • C08F220/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/56Acrylamide; Methacrylamide
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/04Anhydrides, e.g. cyclic anhydrides
    • C08F222/06Maleic anhydride
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10Esters
    • C08F222/12Esters of phenols or saturated alcohols
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/06Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
    • C08F226/10N-Vinyl-pyrrolidone
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/36Amides or imides
    • C08F222/38Amides
    • C08F222/385Monomers containing two or more (meth)acrylamide groups, e.g. N,N'-methylenebisacrylamide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PH1/2012/502181A 2005-12-28 2006-12-26 A biocompatible, non-biodegradable, non-toxic polymer useful for nanoparticle pharmaceutical compositions PH12012502181A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1190KO2005 2005-12-28
PCT/IN2006/000504 WO2007074476A1 (en) 2005-12-28 2006-12-26 A biocompatible, non-biodegradable, non-toxic polymer useful for nanoparticle pharmaceutical compositions

Publications (1)

Publication Number Publication Date
PH12012502181A1 true PH12012502181A1 (en) 2015-06-26

Family

ID=37845115

Family Applications (1)

Application Number Title Priority Date Filing Date
PH1/2012/502181A PH12012502181A1 (en) 2005-12-28 2006-12-26 A biocompatible, non-biodegradable, non-toxic polymer useful for nanoparticle pharmaceutical compositions

Country Status (19)

Country Link
US (2) US8338562B2 (de)
EP (2) EP2172497B1 (de)
JP (1) JP2009522251A (de)
KR (2) KR20080091158A (de)
CN (1) CN101336256B (de)
AR (1) AR058866A1 (de)
AT (1) ATE529454T1 (de)
AU (1) AU2006329554C1 (de)
BR (1) BRPI0620745A2 (de)
CA (1) CA2635469A1 (de)
EA (1) EA017682B1 (de)
ES (2) ES2375740T3 (de)
IL (1) IL192423A0 (de)
MX (1) MX2008008423A (de)
MY (1) MY148575A (de)
NZ (1) NZ569372A (de)
PH (1) PH12012502181A1 (de)
WO (1) WO2007074476A1 (de)
ZA (1) ZA200806548B (de)

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JP2009522251A (ja) 2005-12-28 2009-06-11 ダブール・ファーマ・リミテッド ナノ粒子医薬組成物に有用な生体適合性、非生物分解性、非毒性ポリマー
JP5420946B2 (ja) * 2009-03-23 2014-02-19 富士フイルム株式会社 胆汁酸を含むミノキシジル水性組成物
CN101845120B (zh) * 2010-03-25 2011-11-16 淮阴师范学院 一种温敏和生物可降解性原位凝胶的合成方法
US8772355B2 (en) 2010-11-23 2014-07-08 Howard University Stealth polymeric particles for delivery of bioactive or diagnostic agents
US8921429B2 (en) 2010-11-23 2014-12-30 Howard University Biodegradable stealth polymeric particles fabricated using the macromonomer approach by free radical dispersion polymerization
BR112014012444B1 (pt) 2011-11-23 2021-12-14 Therapeuticsmd, Inc Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
EP2859090A4 (de) * 2012-06-07 2015-11-25 David K Moscatello Zusammensetzungen und verfahren zur entnahme, reinigung, kryokonservierung, rückgewinnung und rückgabe von lipoaspiraten an den arzt für autologe fettgewebeübertragung
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
US20150351428A1 (en) * 2014-06-04 2015-12-10 Animal Science Products, Inc. Methods and compositions for orally dosing postnatal swine
CN104119475B (zh) * 2014-06-26 2016-06-15 中国人民解放军第三○九医院 一种表面功能化的微纳米聚合物凝胶粒子及其制备方法
CN104119474B (zh) * 2014-06-26 2016-06-15 中国人民解放军第三○九医院 一种表面功能化的微纳米聚合物空心粒子及其制备方法
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10176182B2 (en) 2015-08-31 2019-01-08 International Business Machines Corporation File deletion in storage devices based on the deletion priority rules
EP3153227A1 (de) * 2015-10-07 2017-04-12 Evonik Degussa GmbH Verfahren zur herstellung von polyalkenameren für verpackungsanwendungen
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US9931349B2 (en) 2016-04-01 2018-04-03 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition

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JP2517760B2 (ja) 1989-05-11 1996-07-24 新技術事業団 水溶性高分子化医薬製剤
KR940003548U (ko) 1992-08-14 1994-02-21 김형술 세탁물 건조기
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IT1293823B1 (it) * 1997-08-05 1999-03-10 Stefano Gasparini Materiale plastico non tossico avente proprieta' di adsorbenza e assorbenza e relativo procedimento di fabbricazione
US6403816B1 (en) 1997-09-30 2002-06-11 Dabur Research Foundation Betulinic acid derivatives having antiangiogenic activity, processes for producing such derivatives and their use for treating tumor associated angiogenesis
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Also Published As

Publication number Publication date
EP2172497B1 (de) 2013-05-22
AU2006329554A1 (en) 2007-07-05
WO2007074476A1 (en) 2007-07-05
US20130274211A1 (en) 2013-10-17
CA2635469A1 (en) 2007-07-05
NZ569372A (en) 2011-10-28
BRPI0620745A2 (pt) 2013-02-19
MY148575A (en) 2013-04-30
IL192423A0 (en) 2008-12-29
EA017682B1 (ru) 2013-02-28
ES2425075T3 (es) 2013-10-11
ES2375740T3 (es) 2012-03-05
MX2008008423A (es) 2008-09-23
CN101336256A (zh) 2008-12-31
EA200801563A1 (ru) 2009-06-30
ATE529454T1 (de) 2011-11-15
AU2006329554C1 (en) 2013-06-20
EP1971622B1 (de) 2011-10-19
AR058866A1 (es) 2008-02-27
AU2006329554B2 (en) 2013-01-10
EP2172497A1 (de) 2010-04-07
KR20130116954A (ko) 2013-10-24
KR20080091158A (ko) 2008-10-09
CN101336256B (zh) 2012-03-28
ZA200806548B (en) 2010-02-24
US8338562B2 (en) 2012-12-25
EP1971622A1 (de) 2008-09-24
US20090318661A1 (en) 2009-12-24
US8927023B2 (en) 2015-01-06
HK1123814A1 (en) 2009-06-26
JP2009522251A (ja) 2009-06-11

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