PH15023A - Isolation of syn-7-(2-amino-4-thiazolyl)(methoxyimino acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid - Google Patents

Isolation of syn-7-(2-amino-4-thiazolyl)(methoxyimino acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid

Info

Publication number
PH15023A
PH15023A PH24677A PH24677A PH15023A PH 15023 A PH15023 A PH 15023A PH 24677 A PH24677 A PH 24677A PH 24677 A PH24677 A PH 24677A PH 15023 A PH15023 A PH 15023A
Authority
PH
Philippines
Prior art keywords
cephem
acetoxymethyl
syn
thiazolyl
isolation
Prior art date
Application number
PH24677A
Other languages
English (en)
Inventor
Billy Grinnell Jackson
Conna Nezich Gardner
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PH15023A publication Critical patent/PH15023A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/12—Separation; Purification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PH24677A 1979-10-09 1980-10-07 Isolation of syn-7-(2-amino-4-thiazolyl)(methoxyimino acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid PH15023A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/082,822 US4252951A (en) 1979-10-09 1979-10-09 Isolation of syn-7-(2-amino-4-thiazolyl)-(methoxyimino)acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid

Publications (1)

Publication Number Publication Date
PH15023A true PH15023A (en) 1982-05-13

Family

ID=22173679

Family Applications (1)

Application Number Title Priority Date Filing Date
PH24677A PH15023A (en) 1979-10-09 1980-10-07 Isolation of syn-7-(2-amino-4-thiazolyl)(methoxyimino acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid

Country Status (27)

Country Link
US (1) US4252951A (fr)
EP (1) EP0027050B1 (fr)
JP (1) JPS5661388A (fr)
KR (1) KR840000866B1 (fr)
AT (1) AT369008B (fr)
AU (1) AU6306180A (fr)
BE (1) BE885569A (fr)
CA (1) CA1146539A (fr)
CH (1) CH647523A5 (fr)
CS (1) CS215142B2 (fr)
DD (1) DD153375A5 (fr)
DE (1) DE3065181D1 (fr)
DK (1) DK424680A (fr)
ES (1) ES495753A0 (fr)
FI (1) FI803200L (fr)
FR (1) FR2467211A1 (fr)
GB (1) GB2059966B (fr)
GR (1) GR70219B (fr)
HU (1) HU183230B (fr)
IE (1) IE50390B1 (fr)
IL (1) IL61227A (fr)
IT (1) IT1132926B (fr)
PH (1) PH15023A (fr)
PT (1) PT71886B (fr)
RO (1) RO80664B (fr)
YU (1) YU256480A (fr)
ZA (1) ZA806192B (fr)

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JPH07116200B2 (ja) * 1985-09-20 1995-12-13 富山化学工業株式会社 セファロスポリンの製造方法
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WO2000059851A1 (fr) * 1999-04-06 2000-10-12 Sepracor Inc. Derives de la venlafaxine et leurs procedes de preparation et utilisation
EP1219607B1 (fr) * 1999-09-02 2011-04-06 Shionogi & Co., Ltd. Inhibiteur d'integrase contenant des derives heterocycliques aromatiques
CA2284459C (fr) 1999-10-04 2012-12-11 Neokimia Inc. Synthese combinatoire de bibliotheques de composes macrocycliques utiles pour la decouverte de medicaments
WO2001051454A1 (fr) * 2000-01-13 2001-07-19 Emisphere Technologies, Inc. Composes et compositions permettant d"administrer des principes actifs
CN1522148A (zh) * 2001-03-08 2004-08-18 ��Ϧ�������ݴ�ѧ���»� 作为抗感染药的表面两亲聚合物
MXPA04001831A (es) * 2001-08-29 2004-07-08 Neose Technologies Inc Nuevos derivados sinteticos de gangliosidos y composiciones de los mismos.
CA2498944C (fr) * 2002-09-19 2011-05-17 Yasushi Kohno Derives d'aminoalcool, sels connexes et agents immunosuppresseurs
US7056916B2 (en) * 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
CN102432511B (zh) * 2003-03-17 2016-06-08 宾夕法尼亚州大学理事会 表面两亲聚合物和低聚物及其应用
US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
US20050203184A1 (en) 2003-09-10 2005-09-15 Petasis Nicos A. Benzo lipoxin analogues
CN103012213A (zh) * 2004-01-23 2013-04-03 宾夕法尼亚州大学理事会 表面两亲性聚芳基和聚芳基炔基聚合物和低聚物及其用途
ZA200609924B (en) * 2004-05-06 2008-12-31 Univ California Substituted enaminones, their derivatives and uses thereof
US7220742B2 (en) * 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
US20050255050A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Powder formulations for inhalation, comprising enantiomerically pure beta agonists
TWI403334B (zh) * 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
AU2006218805A1 (en) * 2005-02-25 2006-09-08 The Trustees Of The University Of Pennsylvania Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer
US7893304B2 (en) * 2005-02-28 2011-02-22 Meiji Dairies Corporation Hydroquinone long-chain derivatives and/or phenoxy long-chain derivatives, and pharmaceuticals comprising the same
JP5484728B2 (ja) * 2005-08-10 2014-05-07 ジョンズ ホプキンス ユニバーシティ 抗寄生虫治療薬および抗癌治療薬ならびにリジン特異的デメチラーゼ阻害物質として有用なポリアミン類
CA2619402C (fr) * 2005-08-15 2015-02-03 Boehringer Ingelheim International Gmbh Procede de production de betamimetiques
US8592433B2 (en) * 2005-10-28 2013-11-26 Advait Nagle Compounds and compositions as protein kinase inhibitors
EP1954259A2 (fr) * 2005-11-29 2008-08-13 Hammersmith Imanet, Ltd Derives d'amidines pour l'imagerie in vivo
ES2288107B1 (es) * 2006-01-27 2008-11-01 Fundacion Imabis Instituto Mediterraneo Para El Avance De La Biotecnologia Y La Investigacion Sanita Derivados aciclicos saturados e insaturados de cadena larga de sulfamidas como activadores especificos de receptores ppar-alfa.
FR2902999B1 (fr) * 2006-07-03 2012-09-28 Oreal Utilisation de derives c-glycoside a titre d'actif prodesquamant
FR2903004B1 (fr) * 2006-07-03 2009-07-10 Oreal Utilisation en cosmetique d'un derive c-glycoside en association avec de l'acide ascorbique
FR2902996B1 (fr) * 2006-07-03 2008-09-26 Oreal Compositions cosmetiques associant un derive c-glycoside et un derive n-acylaminoamide
US20090075935A1 (en) * 2006-07-03 2009-03-19 L'oreal Composition comprising at least one c-glycoside derivative and at least one hyaluronic acid and its cosmetic use
AU2007334428B2 (en) * 2006-12-14 2014-05-29 Teva Pharmaceutical Industries, Ltd. Crystalline solid rasagiline base
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US7696383B2 (en) * 2007-06-26 2010-04-13 Solvay Pharmaceuticals B.V. N-oxides of venlafaxine and o-desmethylvenlafaxine as prodrugs
FR2920000B1 (fr) * 2007-08-13 2010-01-29 Oreal Composition cosmetique ou pharmaceutique contenant de l'acide hyaluronique, et procede cosmetique pour diminuer les signes du vieilissement
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3925372A (en) * 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
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US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
DE2760484C2 (fr) 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp

Also Published As

Publication number Publication date
IT1132926B (it) 1986-07-09
EP0027050B1 (fr) 1983-10-05
DE3065181D1 (en) 1983-11-10
KR840000866B1 (ko) 1984-06-20
IT8025200A0 (it) 1980-10-08
DK424680A (da) 1981-04-10
YU256480A (en) 1983-02-28
ATA498080A (de) 1982-04-15
CA1146539A (fr) 1983-05-17
AU6306180A (en) 1981-04-16
FR2467211A1 (fr) 1981-04-17
CH647523A5 (fr) 1985-01-31
JPS5661388A (en) 1981-05-26
EP0027050A1 (fr) 1981-04-15
HU183230B (en) 1984-04-28
GB2059966B (en) 1983-09-01
PT71886A (en) 1980-11-01
DD153375A5 (de) 1982-01-06
BE885569A (fr) 1981-04-08
ES8201166A1 (es) 1981-12-01
ZA806192B (en) 1982-05-26
FR2467211B1 (fr) 1983-06-10
KR830004314A (ko) 1983-07-09
IL61227A0 (en) 1980-12-31
IL61227A (en) 1983-07-31
ES495753A0 (es) 1981-12-01
IE802086L (en) 1981-04-09
GB2059966A (en) 1981-04-29
AT369008B (de) 1982-11-25
CS215142B2 (en) 1982-07-30
FI803200A7 (fi) 1981-04-10
RO80664B (ro) 1983-02-28
US4252951A (en) 1981-02-24
PT71886B (en) 1981-08-13
FI803200L (fi) 1981-04-10
RO80664A (fr) 1983-02-15
GR70219B (fr) 1982-08-31
IE50390B1 (en) 1986-04-16

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