PH20020A - New 5-methyl-6-phenyl-4,5-dihydro-1,2,4-triazine derivatives,their composition and use - Google Patents

New 5-methyl-6-phenyl-4,5-dihydro-1,2,4-triazine derivatives,their composition and use

Info

Publication number: PH20020A
Authority: PH; Philippines
Prior art keywords: triazine derivatives; new; dihydro; phenyl; methyl
Prior art date: 1983-04-22

Application number

PH30552A

Other languages

English (en)

Inventor

Tsutomu Teraji

Youchi Shiokawa

Kazuo Okumura

Yoshinari Sato

Original Assignee

Fujisawa Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-04-22

Filing date

1984-04-13

Publication date

1986-09-01

1984-04-13 Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co

1986-09-01 Publication of PH20020A publication Critical patent/PH20020A/en

Links

XAVLTINDXPCHPO-UHFFFAOYSA-N 5-methyl-6-phenyl-2,5-dihydro-1,2,4-triazine Chemical class CC1NC=NN=C1C1=CC=CC=C1 XAVLTINDXPCHPO-UHFFFAOYSA-N 0.000 title 1
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000004122 cyclic group Chemical group 0.000 abstract 2
125000005027 hydroxyaryl group Chemical group 0.000 abstract 2
241000282414 Homo sapiens Species 0.000 abstract 1
206010020772 Hypertension Diseases 0.000 abstract 1
241001465754 Metazoa Species 0.000 abstract 1
208000007536 Thrombosis Diseases 0.000 abstract 1
208000025865 Ulcer Diseases 0.000 abstract 1
125000002015 acyclic group Chemical group 0.000 abstract 1
125000005236 alkanoylamino group Chemical group 0.000 abstract 1
125000004466 alkoxycarbonylamino group Chemical group 0.000 abstract 1
125000004656 alkyl sulfonylamino group Chemical group 0.000 abstract 1
125000004414 alkyl thio group Chemical group 0.000 abstract 1
125000005281 alkyl ureido group Chemical group 0.000 abstract 1
125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000005110 aryl thio group Chemical group 0.000 abstract 1
229910052736 halogen Chemical group 0.000 abstract 1
150000002367 halogens Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
-1 hydroxy, protected hydroxy, amino, cyano, mercapto Chemical group 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
150000003918 triazines Chemical class 0.000 abstract 1
231100000397 ulcer Toxicity 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Diabetes (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicinal Preparation (AREA)
Fats And Perfumes (AREA)
Color Electrophotography (AREA)
Indole Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

PH30552A 1983-04-22 1984-04-13 New 5-methyl-6-phenyl-4,5-dihydro-1,2,4-triazine derivatives,their composition and use PH20020A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP58072013A JPS59196874A (ja)	1983-04-22	1983-04-22	トリアジン誘導体

Publications (1)

Publication Number	Publication Date
PH20020A true PH20020A (en)	1986-09-01

Family

ID=13477098

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH30552A PH20020A (en)	1983-04-22	1984-04-13	New 5-methyl-6-phenyl-4,5-dihydro-1,2,4-triazine derivatives,their composition and use

Country Status (15)

Country	Link
US (1)	US4618610A (de)
EP (1)	EP0123254B1 (de)
JP (1)	JPS59196874A (de)
KR (1)	KR840008341A (de)
AT (1)	ATE35259T1 (de)
AU (1)	AU2701584A (de)
DE (1)	DE3472255D1 (de)
DK (1)	DK201684A (de)
ES (3)	ES8507517A1 (de)
FI (1)	FI841527A7 (de)
GR (1)	GR81788B (de)
HU (1)	HU192010B (de)
NO (1)	NO841594L (de)
PH (1)	PH20020A (de)
ZA (1)	ZA842700B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4898862A (en) *	1986-03-20	1990-02-06	Sankyo Company Limited	1,2,4-triazinone derivatives, their preparation and use
GB8903130D0 (en) *	1989-02-11	1989-03-30	Orion Yhtymae Oy	Substituted pyridazinones
DE4239540A1 (de) *	1992-11-25	1994-05-26	Asta Medica Ag	Neue heterocyclische Verbindungen mit antiasthmatischer/antiallergischer, entzündungshemmender, positiv inotroper und blutdrucksenkender Wirkung
DE19929781A1 (de) *	1999-06-29	2001-01-04	Bayer Ag	N-[4-(6-Oxotetrahydrotriazinyl)phenyl]amide und ihre Verwendung
MX373178B (es) *	2007-04-03	2020-04-22	Fmc Corp Star	Fungicidas de benceno sustituido.
JOP20200024A1 (ar)	2017-08-04	2020-02-02	Bayer Ag	مركبات ثنائي هيدروكساديازينون
EP3661917B1 (de)	2017-08-04	2022-05-11	Bayer Aktiengesellschaft	6-((3-trifluoromethyl)phenyl)-4,5-dihydropyridazin-3(2h)-on-derivate als pde3a and pde3b inhibitoren zur behandlung von krebs
AU2020215088A1 (en)	2019-02-01	2021-07-22	Bayer Aktiengesellschaft	1,2,4-triazin-3(2H)-one compounds for the treatment of hyperproliferative diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0052442B1 (de) *	1980-11-14	1985-09-11	Imperial Chemical Industries Plc	Heterocyclische Derivate
US4616014A (en) *	1981-10-22	1986-10-07	Fujisawa Pharmaceutical Co., Ltd.	Triazine derivatives, and pharmaceutical compositions comprising the same
US4495185A (en) *	1981-11-12	1985-01-22	Imperial Chemical Industries, Plc	1,2,4-Triazin-3(2H) ones
GB8310435D0 (en) *	1983-04-18	1983-05-25	Fujisawa Pharmaceutical Co	Triazine derivatives

1983
- 1983-04-22 JP JP58072013A patent/JPS59196874A/ja active Granted
1984
- 1984-04-11 ZA ZA842700A patent/ZA842700B/xx unknown
- 1984-04-12 GR GR74405A patent/GR81788B/el unknown
- 1984-04-13 PH PH30552A patent/PH20020A/en unknown
- 1984-04-16 EP EP84104295A patent/EP0123254B1/de not_active Expired
- 1984-04-16 AT AT84104295T patent/ATE35259T1/de not_active IP Right Cessation
- 1984-04-16 DE DE8484104295T patent/DE3472255D1/de not_active Expired
- 1984-04-17 AU AU27015/84A patent/AU2701584A/en not_active Abandoned
- 1984-04-17 FI FI841527A patent/FI841527A7/fi not_active Application Discontinuation
- 1984-04-18 ES ES531793A patent/ES8507517A1/es not_active Expired
- 1984-04-18 DK DK201684A patent/DK201684A/da not_active Application Discontinuation
- 1984-04-18 NO NO841594A patent/NO841594L/no unknown
- 1984-04-19 KR KR1019840002067A patent/KR840008341A/ko not_active Ceased
- 1984-04-20 HU HU841546A patent/HU192010B/hu unknown
- 1984-04-23 US US06/603,173 patent/US4618610A/en not_active Expired - Fee Related
1985
- 1985-01-17 ES ES539653A patent/ES8602706A1/es not_active Expired
- 1985-01-17 ES ES539654A patent/ES8606305A1/es not_active Expired

Also Published As

Publication number	Publication date
DK201684D0 (da)	1984-04-18
DE3472255D1 (en)	1988-07-28
ATE35259T1 (de)	1988-07-15
HU192010B (en)	1987-04-28
FI841527A0 (fi)	1984-04-17
GR81788B (de)	1984-12-12
ES531793A0 (es)	1985-09-01
FI841527A7 (fi)	1984-10-23
EP0123254B1 (de)	1988-06-22
US4618610A (en)	1986-10-21
HUT34173A (en)	1985-02-28
KR840008341A (ko)	1984-12-14
AU2701584A (en)	1984-10-25
ES539653A0 (es)	1985-11-16
JPS59196874A (ja)	1984-11-08
ES8507517A1 (es)	1985-09-01
JPH0235752B2 (de)	1990-08-13
EP0123254A1 (de)	1984-10-31
DK201684A (da)	1984-10-23
ES8606305A1 (es)	1986-04-16
ES539654A0 (es)	1986-04-16
ZA842700B (en)	1984-11-28
ES8602706A1 (es)	1985-11-16
NO841594L (no)	1984-10-23

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PL137289B2 (en)	1986-05-31	Fungicide
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BG60032B2 (bg)	1993-07-30	Метод за получаване на триазолни производни
IT1250749B (it)	1995-04-21	Composti eterociclici ad attivita' a ii antagonista
PH20020A (en)	1986-09-01	New 5-methyl-6-phenyl-4,5-dihydro-1,2,4-triazine derivatives,their composition and use
EP0439321A3 (en)	1992-04-01	Thiazolidine derivatives having anti-hypertensive activity and their therapeutic use
ES2001697A6 (es)	1988-06-01	Procedimiento para preparar 2-aminopurinas sustituidas en posiciones 6 y 9
MX9300927A (es)	1994-08-31	Compuestos terapeuticos de triazina y su empleo.
ZA895387B (en)	1990-04-25	Novel s-adenosyl methionine decarboxylase inhibitors
LTIP378A (en)	1994-09-25	Methylpiperazinoazepine derivatives, preparation and use tereof
PT73718B (en)	1982-12-30	Process for the preparation of substituted 6-halogeno-tert.- -butyl-1,2,4-triazin-5-ones with herbicidal effect
ATE97811T1 (de)	1993-12-15	Antipsychotisch wirksames imidazobenzodiazepin.
FI840352A0 (fi)	1984-01-27	Fungicida triazolfoereningar
DE3561948D1 (en)	1988-04-28	Oximinophosphoric acid derivatives, process for their preparation and their use as pesticides
EP0447812A3 (en)	1992-07-08	Use of a dihydropyridine to improve the inner ear blood circulation
MX9704548A (es)	1998-02-28	Compuestos peptidomesticos antiherpes.
EA199800575A1 (ru)	1998-12-24	Производные пиперазина