PH20585A - Novel amidine compound - Google Patents

Novel amidine compound

Info

Publication number
PH20585A
PH20585A PH32559A PH32559A PH20585A PH 20585 A PH20585 A PH 20585A PH 32559 A PH32559 A PH 32559A PH 32559 A PH32559 A PH 32559A PH 20585 A PH20585 A PH 20585A
Authority
PH
Philippines
Prior art keywords
amidine compound
novel amidine
novel
compound
amidine
Prior art date
Application number
PH32559A
Other languages
English (en)
Inventor
Setsuro Fujii
Toshiyuki Okutome
Toyoo Nakatama
Shigeki Nunomura
Kimio Sudo
Shinichi Watanabe
Masateru Kurumi
Takuo Aoyama
Original Assignee
Torii & Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torii & Co Ltd filed Critical Torii & Co Ltd
Publication of PH20585A publication Critical patent/PH20585A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PH32559A 1984-07-25 1985-07-23 Novel amidine compound PH20585A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15504584A JPS6133173A (ja) 1984-07-25 1984-07-25 アミジン化合物

Publications (1)

Publication Number Publication Date
PH20585A true PH20585A (en) 1987-02-20

Family

ID=15597463

Family Applications (1)

Application Number Title Priority Date Filing Date
PH32559A PH20585A (en) 1984-07-25 1985-07-23 Novel amidine compound

Country Status (19)

Country Link
US (2) US4777182A (fr)
EP (1) EP0190356B1 (fr)
JP (1) JPS6133173A (fr)
KR (2) KR870001087B1 (fr)
AU (1) AU567039B2 (fr)
CA (1) CA1254205A (fr)
CS (1) CS255891B2 (fr)
DD (1) DD235637A5 (fr)
DE (1) DE3582057D1 (fr)
DK (1) DK169069B1 (fr)
ES (1) ES8607218A1 (fr)
FI (1) FI78461C (fr)
HU (1) HU195769B (fr)
MX (1) MX160912A (fr)
NO (1) NO163954C (fr)
PH (1) PH20585A (fr)
SU (1) SU1456008A3 (fr)
WO (1) WO1986000893A1 (fr)
ZA (1) ZA855552B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3824236C1 (fr) * 1988-07-16 1989-12-28 Heidelberger Druckmaschinen Ag, 6900 Heidelberg, De
CA2032420A1 (fr) * 1989-12-22 1991-06-23 Akira Okuyama Derives de la phenylguanidine
US5238964A (en) * 1990-04-05 1993-08-24 Torii & Co., Ltd. Agent for treatment of cerebrovascular contraction
US5652237A (en) * 1994-09-09 1997-07-29 Warner-Lambert Company 2-substituted-4H-3, 1-benzoxazin-4-ones and benzthiazin-4-ones as inhibitors of complement C1r protease for the treatment of inflammatory processes
WO1996020917A1 (fr) * 1995-01-05 1996-07-11 Torii Pharmaceutical Co., Ltd. Derives d'ester d'amidinonaphtyle substitues
RU2142799C1 (ru) * 1995-01-05 1999-12-20 Тории Фармасьютикал Ко., Лтд Тромболитические средства
WO1999047128A1 (fr) 1998-03-19 1999-09-23 Bristol-Myers Squibb Company Systeme d'apport a liberation lente biphasique destine a des medicaments a solubilite elevee et procede associe
WO2001077082A1 (fr) * 1999-06-02 2001-10-18 Torii Pharmaceutical Co., Ltd. Derives de naphtalene
WO2001094299A1 (fr) * 2000-06-08 2001-12-13 Shizuoka Coffein Co., Ltd. Derives de benzene
EP2236136A1 (fr) * 2005-05-17 2010-10-06 Santen Pharmaceutical Co., Ltd. Inhibiteur de l'angiogenèse contenant un dérivé amine en tant qu'ingrédient actif
US20090088472A1 (en) * 2005-05-17 2009-04-02 Kouji Oohashi Protective Agent for Neuronal Cell Comprising Amidino Derivative as Active Ingredient
US20100063146A1 (en) * 2006-11-07 2010-03-11 Medof M Edward Method for treating disorders related to complement activation
RU2596787C2 (ru) 2010-07-09 2016-09-10 БиЭйчВи ФАРМА, ИНК. Комбинированная система доставки с немедленным/замедленным высвобождением для лекарственных средств с коротким периодом полувыведения, в том числе для ремоглифлозина
WO2014007326A1 (fr) * 2012-07-04 2014-01-09 味の素株式会社 Procédé de préparation de mésylate de nafamostat

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4292429A (en) * 1978-03-08 1981-09-29 Ciba-Geigy Corporation Imidazole urea and amido compounds
AU527371B2 (en) * 1980-09-16 1983-03-03 Torii & Co., Ltd. Amidine
JPS57179146A (en) * 1981-04-28 1982-11-04 Torii Yakuhin Kk Amidine compound
JPS60130561A (ja) * 1983-12-16 1985-07-12 Torii Yakuhin Kk アミジン誘導体およびそれを含む強心剤

Also Published As

Publication number Publication date
CA1254205A (fr) 1989-05-16
FI78461B (fi) 1989-04-28
KR860700250A (ko) 1986-08-01
US4777182A (en) 1988-10-11
EP0190356B1 (fr) 1991-03-06
ZA855552B (en) 1986-03-26
WO1986000893A1 (fr) 1986-02-13
FI860904A0 (fi) 1986-03-04
HU195769B (en) 1988-07-28
DK169069B1 (da) 1994-08-08
EP0190356A4 (fr) 1987-12-09
SU1456008A3 (ru) 1989-01-30
NO860865L (no) 1986-04-10
HUT42433A (en) 1987-07-28
JPH0461868B2 (fr) 1992-10-02
CS546385A2 (en) 1987-07-16
DK96286D0 (da) 1986-03-03
US4820730A (en) 1989-04-11
KR870001087B1 (ko) 1987-06-04
NO163954C (no) 1990-08-15
CS255891B2 (en) 1988-03-15
AU567039B2 (en) 1987-11-05
DD235637A5 (de) 1986-05-14
DK96286A (da) 1986-03-03
FI860904A7 (fi) 1986-03-04
FI78461C (fi) 1989-08-10
JPS6133173A (ja) 1986-02-17
DE3582057D1 (en) 1991-04-11
EP0190356A1 (fr) 1986-08-13
NO163954B (no) 1990-05-07
MX160912A (es) 1990-06-14
ES545482A0 (es) 1986-05-16
ES8607218A1 (es) 1986-05-16
AU4549285A (en) 1986-02-25

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