PH21926A - 6-phenyl-1,2,4-triazine derivatives - Google Patents

6-phenyl-1,2,4-triazine derivatives

Info

Publication number
PH21926A
PH21926A PH31367A PH31367A PH21926A PH 21926 A PH21926 A PH 21926A PH 31367 A PH31367 A PH 31367A PH 31367 A PH31367 A PH 31367A PH 21926 A PH21926 A PH 21926A
Authority
PH
Philippines
Prior art keywords
phenyl
triazine derivatives
triazine
derivatives
Prior art date
Application number
PH31367A
Other languages
English (en)
Inventor
Geoffrey Allan
Alistair Ainslie Miller
David Alan Sawyer
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of PH21926A publication Critical patent/PH21926A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PH31367A 1983-10-27 1984-10-26 6-phenyl-1,2,4-triazine derivatives PH21926A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838328757A GB8328757D0 (en) 1983-10-27 1983-10-27 Chemical compounds

Publications (1)

Publication Number Publication Date
PH21926A true PH21926A (en) 1988-04-08

Family

ID=10550834

Family Applications (1)

Application Number Title Priority Date Filing Date
PH31367A PH21926A (en) 1983-10-27 1984-10-26 6-phenyl-1,2,4-triazine derivatives

Country Status (21)

Country Link
US (1) US4649139A (pl)
EP (1) EP0142306A3 (pl)
JP (1) JPS60109577A (pl)
KR (1) KR890000991B1 (pl)
AU (1) AU564667B2 (pl)
CA (1) CA1261328A (pl)
DD (1) DD224033A5 (pl)
DK (1) DK512184A (pl)
ES (1) ES8606304A1 (pl)
FI (1) FI844212A7 (pl)
GB (1) GB8328757D0 (pl)
GR (1) GR80723B (pl)
HU (1) HU191566B (pl)
IL (1) IL73332A (pl)
MC (1) MC1628A1 (pl)
NZ (1) NZ210000A (pl)
PH (1) PH21926A (pl)
PL (1) PL144899B1 (pl)
PT (1) PT79416B (pl)
SU (1) SU1371500A3 (pl)
ZA (1) ZA848388B (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8613183D0 (en) * 1986-05-30 1986-07-02 Wellcome Found Triazine salt
GB9012312D0 (en) * 1990-06-01 1990-07-18 Wellcome Found Pharmacologically active cns compounds
GB9218113D0 (en) * 1992-08-26 1992-10-14 Lilly Industries Ltd Pharmaceutical compounds
GB9726987D0 (en) 1997-12-22 1998-02-18 Glaxo Group Ltd Compounds
WO2001049669A1 (en) * 2000-01-03 2001-07-12 Rpg Life Sciences Limited A process for the preparation of 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine, commonly known as lamotrigine
IL134730A (en) * 2000-02-25 2003-10-31 Chemagis Ltd Process for preparing substituted benzoyl cyanide amidinohydrazones
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
CN102379684B (zh) 2005-04-28 2014-11-19 普罗透斯数字保健公司 药物信息系统
GB0613836D0 (en) 2006-07-13 2006-08-23 Univ Greenwich New medical use of triazine derivatives
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
GB0800741D0 (en) 2008-01-16 2008-02-20 Univ Greenwich Cyclic triazo and diazo sodium channel blockers
EP2398500B1 (en) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
GB2471713A (en) 2009-07-08 2011-01-12 Univ Greenwich 1,2,4-triazine derivatives and their use as sodium channel blockers
GB2471729A (en) 2009-07-08 2011-01-12 Univ Greenwich 1,2,4-triazine derivatives and their use as sodium channel blockers
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
WO2016198878A1 (en) 2015-06-12 2016-12-15 University Of Greenwich Triazine derivatives as interferon-gamma inhibitors
CN109810070B (zh) * 2019-01-29 2022-03-15 太原理工大学 一种含有双酰氧基结构的三嗪酮衍生物及其制备方法和应用
GB202006080D0 (en) 2020-04-24 2020-06-10 Univ Greenwich Cytokine storm syndrome
GB202006076D0 (en) 2020-04-24 2020-06-10 Univ Greenwich Interleukin inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB759014A (en) * 1952-02-26 1956-10-10 Wellcome Found Improvements in triazines and their manufacture
BG15760A3 (bg) * 1968-06-29 1976-06-21 Неизвестен Метод за получаване на производни на 5-имино- 1, 2, 4- триазина
US3637688A (en) * 1970-01-09 1972-01-25 American Home Prod 6-(fluoro and trifluoromethyl phenyl)-3 5-diamino - 1 2 4 - triazines and substituted - 6 - phenylalkyl-3,5-diamino-1 2 4-triazines
DE2003144C3 (de) * 1970-01-24 1980-01-10 Bayer Ag, 5090 Leverkusen 5-Imino-6-alkyl-1^2,4-triazin-Derivate und Verfahren zu deren Herstellung
EP0021121B1 (en) * 1979-06-01 1983-05-11 The Wellcome Foundation Limited 1,2,4-triazine derivatives, process for preparing such compounds and pharmaceutical compositions containing them
JPS5625170A (en) * 1979-06-01 1981-03-10 Wellcome Found Triazine derivative
US4616014A (en) * 1981-10-22 1986-10-07 Fujisawa Pharmaceutical Co., Ltd. Triazine derivatives, and pharmaceutical compositions comprising the same

Also Published As

Publication number Publication date
DK512184A (da) 1985-04-28
FI844212L (fi) 1985-04-28
KR890000991B1 (ko) 1989-04-15
US4649139A (en) 1987-03-10
IL73332A0 (en) 1985-01-31
ES8606304A1 (es) 1986-04-16
DK512184D0 (da) 1984-10-26
EP0142306A3 (en) 1986-11-20
IL73332A (en) 1988-06-30
AU3475884A (en) 1985-05-09
EP0142306A2 (en) 1985-05-22
HU191566B (en) 1987-03-30
PL144899B1 (en) 1988-07-30
JPS60109577A (ja) 1985-06-15
MC1628A1 (fr) 1985-09-26
AU564667B2 (en) 1987-08-20
CA1261328A (en) 1989-09-26
ZA848388B (en) 1986-06-25
DD224033A5 (de) 1985-06-26
GB8328757D0 (en) 1983-11-30
ES537104A0 (es) 1986-04-16
HUT36102A (en) 1985-08-28
PL250213A1 (en) 1985-12-03
NZ210000A (en) 1987-08-31
KR850002964A (ko) 1985-05-28
GR80723B (en) 1985-02-07
FI844212A7 (fi) 1985-04-28
SU1371500A3 (ru) 1988-01-30
PT79416B (en) 1986-11-13
FI844212A0 (fi) 1984-10-26
PT79416A (en) 1984-11-01

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