PH22300A - Galactosyl-insulin conjugates, useful in treating diabetics - Google Patents

Galactosyl-insulin conjugates, useful in treating diabetics

Info

Publication number: PH22300A
Authority: PH; Philippines
Prior art keywords: galactosyl; useful; insulin conjugates; treating diabetics; diabetics
Prior art date: 1983-03-21

Application number

PH30424A

Other languages

English (en)

Inventor

Myhre David Vernon

Geho Walter Blair

Original Assignee

Procter & Gamble

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-03-21

Filing date

1984-03-21

Publication date

1988-07-22

1984-03-21 Application filed by Procter & Gamble filed Critical Procter & Gamble

1988-07-22 Publication of PH22300A publication Critical patent/PH22300A/en

Links

229940125396 insulin Drugs 0.000 title 1
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Substances N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/02—Monosaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Biophysics (AREA)
Endocrinology (AREA)
Zoology (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

PH30424A 1983-03-21 1984-03-21 Galactosyl-insulin conjugates, useful in treating diabetics PH22300A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US47755583A	1983-03-21	1983-03-21

Publications (1)

Publication Number	Publication Date
PH22300A true PH22300A (en)	1988-07-22

Family

ID=23896415

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH30424A PH22300A (en)	1983-03-21	1984-03-21	Galactosyl-insulin conjugates, useful in treating diabetics

Country Status (6)

Country	Link
EP (1)	EP0119650A3 (de)
JP (1)	JPS6011426A (de)
AU (1)	AU2589984A (de)
ES (1)	ES8606407A1 (de)
PH (1)	PH22300A (de)
ZA (1)	ZA842051B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8504099D0 (en) *	1985-02-18	1985-03-20	Wellcome Found	Physiologically active substances
DK111489D0 (da) *	1989-03-08	1989-03-08	Novo Nordisk As	Peptider
ID16479A (id) *	1995-06-23	1997-10-02	Oxford Glycosciences Uk Ltd	Senyawa-senyawa pengobatan
GB9626450D0 (en) *	1996-12-20	1997-02-05	Oxford Glycosciences Uk Ltd	Therapeutic compounds
WO2010088300A1 (en)	2009-01-28	2010-08-05	Smartcells, Inc.	Crystalline insulin-conjugates
WO2010088286A1 (en)	2009-01-28	2010-08-05	Smartcells, Inc.	Synthetic conjugates and uses thereof
WO2010088268A1 (en)	2009-01-28	2010-08-05	Smartcells, Inc.	Exogenously triggered controlled release materials and uses thereof
BRPI1007457A2 (pt)	2009-01-28	2015-08-25	Smartcells Inc	Conjungado, formulação de liberação prolongada, e, sistema de distribuição de bomba.
WO2010107520A1 (en)	2009-03-20	2010-09-23	Smartcells, Inc.	Soluble non-depot insulin conjugates and uses thereof
US8623345B2 (en)	2009-03-20	2014-01-07	Smartcells	Terminally-functionalized conjugates and uses thereof
AU2011282977A1 (en)	2010-07-28	2013-02-21	Smartcells, Inc.	Drug-ligand conjugates, synthesis thereof, and intermediates thereto
EP2598522A4 (de)	2010-07-28	2014-11-12	Smartcells Inc	Rekombinante lektine, bindungsstellenmodifizierte lektine und anwendungen davon
JP2013535467A (ja)	2010-07-28	2013-09-12	スマートセルズ・インコーポレイテツド	組換えにより発現されたインスリンポリペプチドおよびその使用
US9517257B2 (en)	2010-08-10	2016-12-13	Ecole Polytechnique Federale De Lausanne (Epfl)	Erythrocyte-binding therapeutics
EP2603520A4 (de)	2010-08-10	2014-02-19	Ecole Polytech	Erythrozytenbindende therapeutika
US9850296B2 (en)	2010-08-10	2017-12-26	Ecole Polytechnique Federale De Lausanne (Epfl)	Erythrocyte-binding therapeutics
US9707276B2 (en)	2012-12-03	2017-07-18	Merck Sharp & Dohme Corp.	O-glycosylated carboxy terminal portion (CTP) peptide-based insulin and insulin analogues
KR20160065930A (ko)	2013-10-04	2016-06-09	머크 샤프 앤드 돔 코포레이션	글루코스-반응성 인슐린 접합체
US10046056B2 (en)	2014-02-21	2018-08-14	École Polytechnique Fédérale De Lausanne (Epfl)	Glycotargeting therapeutics
SG11201606761RA (en)	2014-02-21	2016-09-29	Ecole Polytecnique Federale De Lausanne Epfl Epfl Tto	Glycotargeting therapeutics
US10953101B2 (en)	2014-02-21	2021-03-23	École Polytechnique Fédérale De Lausanne (Epfl)	Glycotargeting therapeutics
US10946079B2 (en)	2014-02-21	2021-03-16	Ecole Polytechnique Federale De Lausanne	Glycotargeting therapeutics
WO2018232176A1 (en)	2017-06-16	2018-12-20	The University Of Chicago	Compositions and methods for inducing immune tolerance
EP3790577A4 (de)	2018-05-09	2022-04-27	The University of Chicago	Zusammensetzungen und verfahren im zusammenhang mit immuntoleranz

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3847890A (en) *	1971-11-01	1974-11-12	A Green	Acidic monosaccharide-substituted proteins
EP0009842B1 (de) *	1978-10-02	1982-11-10	THE PROCTER & GAMBLE COMPANY	Liposome zur Freigabe von Arzneimitteln und eine ein Arzneimittelsystem mit liposomen enthaltende Bereitung
US4348387A (en) *	1979-07-31	1982-09-07	The Rockefeller University	Method and system for the controlled release of biologically active substances to a body fluid

1984
- 1984-03-08 EP EP84200328A patent/EP0119650A3/de not_active Withdrawn
- 1984-03-20 ES ES530759A patent/ES8606407A1/es not_active Expired
- 1984-03-20 ZA ZA842051A patent/ZA842051B/xx unknown
- 1984-03-20 AU AU25899/84A patent/AU2589984A/en not_active Abandoned
- 1984-03-21 PH PH30424A patent/PH22300A/en unknown
- 1984-03-21 JP JP59054143A patent/JPS6011426A/ja active Pending

Also Published As

Publication number	Publication date
AU2589984A (en)	1984-09-27
ES530759A0 (es)	1986-04-01
JPS6011426A (ja)	1985-01-21
EP0119650A3 (de)	1987-09-30
ES8606407A1 (es)	1986-04-01
EP0119650A2 (de)	1984-09-26
ZA842051B (en)	1984-10-31

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