PH22406A - Novel benzodiazepine derivatives and their preparation and use - Google Patents

Novel benzodiazepine derivatives and their preparation and use

Info

Publication number
PH22406A
PH22406A PH35125A PH35125A PH22406A PH 22406 A PH22406 A PH 22406A PH 35125 A PH35125 A PH 35125A PH 35125 A PH35125 A PH 35125A PH 22406 A PH22406 A PH 22406A
Authority
PH
Philippines
Prior art keywords
benzodiazepine derivatives
preparation
novel benzodiazepine
chem
alkyl
Prior art date
Application number
PH35125A
Other languages
English (en)
Inventor
Watjen Frank
Original Assignee
Ferrosan As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrosan As filed Critical Ferrosan As
Publication of PH22406A publication Critical patent/PH22406A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Power Steering Mechanism (AREA)
PH35125A 1986-04-16 1987-04-10 Novel benzodiazepine derivatives and their preparation and use PH22406A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK174086A DK174086D0 (da) 1986-04-16 1986-04-16 Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme

Publications (1)

Publication Number Publication Date
PH22406A true PH22406A (en) 1988-08-26

Family

ID=8107685

Family Applications (1)

Application Number Title Priority Date Filing Date
PH35125A PH22406A (en) 1986-04-16 1987-04-10 Novel benzodiazepine derivatives and their preparation and use

Country Status (19)

Country Link
US (1) US4772599A (de)
EP (1) EP0241682B1 (de)
JP (1) JPH07116195B2 (de)
KR (1) KR940009784B1 (de)
AT (1) ATE58737T1 (de)
AU (1) AU588994B2 (de)
CA (1) CA1293724C (de)
DE (2) DE3766401D1 (de)
DK (1) DK174086D0 (de)
ES (1) ES2037673T3 (de)
FI (1) FI87458C (de)
GR (1) GR3001160T3 (de)
IE (1) IE60488B1 (de)
IL (1) IL82117A (de)
NO (1) NO164655C (de)
NZ (1) NZ219915A (de)
PH (1) PH22406A (de)
PT (1) PT84690B (de)
ZA (1) ZA872630B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU594676B2 (en) * 1985-05-17 1990-03-15 Novo Nordisk A/S Oxadiazolyl imidazobenaodiazepine compound, pharmaceutical composition containing said compound, method of preparing said compound and method of treating a central nervous system ailment
US4622321A (en) * 1985-05-17 1986-11-11 As Ferrosan Oxadiazolylimidazobenzodiazepine, compositions, and method
FI880814A7 (fi) * 1987-03-10 1988-09-11 Hoffmann La Roche Imidazodiazepin-derivat.
GB8720414D0 (en) * 1987-08-28 1987-10-07 Roussel Lab Ltd Chemical compounds
CA2015336A1 (en) * 1989-05-19 1990-11-19 F. Hoffmann-La Roche Ag Imidazodiazepines for the treatment of neurological symptoms
US4904654A (en) * 1989-07-26 1990-02-27 Merck & Co., Inc. 7-chloro-5,6-dihydro-3-(5-(2-hydroxy-isopropyl)-1,2,4-oxadiazol-3-yl)-5-methyl-6-oxo-4H-imidazo[1,5a][1,4]benzodiazepine
CA2143246C (en) * 1994-03-16 2000-08-22 Thierry Godel Imidazodiazepines
US5438035A (en) * 1994-06-24 1995-08-01 American Cyanamid Company Methods for controlling undesirable plant species with benzodiazepine compounds
US5706829A (en) * 1996-06-06 1998-01-13 Creighton University Method for treating neurocardiogenic syncope
KR100283474B1 (ko) * 1999-01-18 2001-02-15 박호군 Ｎ₂ｓ₂리간드가 포함된 플루마제닐 유도체 및 그의 제조방법
TWI239333B (en) 2000-11-16 2005-09-11 Hoffmann La Roche Benzodiazepine derivatives as GABA A receptor modulators
ATE402707T1 (de) * 2004-10-12 2008-08-15 Hoffmann La Roche Imidazoä1,5aütriazoloä1,5dübenzodiazepin- derivative zur behandlung kognitiver störungen
NZ554439A (en) * 2004-10-20 2009-09-25 Hoffmann La Roche Imidazo-benzodiazepine derivatives
RU2007114763A (ru) * 2004-10-20 2008-11-27 Ф.Хоффманн-Ля Рош Аг (Ch) Галогенозамещенные производные бензодиазепинов
WO2006063708A1 (en) * 2004-12-14 2006-06-22 F.Hoffmann-La Roche Ag Tetracyclic imidazo-benzodiazepines as gaba receptors modulators
US20090054412A1 (en) * 2007-08-20 2009-02-26 John Alan Kemp Treatment of Sleep Disorders
CN101827597B (zh) * 2007-08-20 2013-03-13 伊沃泰克国际有限责任公司 睡眠障碍的治疗

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1143728A (en) * 1979-10-04 1983-03-29 Max Gerecke Imidazodiazepine derivatives
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
CA1185602A (en) * 1981-02-27 1985-04-16 Emilio Kyburz Imidazodiazepines
MC1528A1 (fr) * 1982-07-21 1984-04-13 Hoffmann La Roche Imidazobenzodiazepines
DK151808C (da) * 1982-11-16 1988-06-20 Ferrosan As Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-oe1,4aa-benzodiazepinderivater
CS249146B2 (en) * 1984-01-19 1987-03-12 Hoffmann La Roche Method of new imidazodiazepine's derivatives production
CA1259612A (en) * 1985-02-28 1989-09-19 Emilio Kyburz Imidazodiazepine derivatives
AU587802B2 (en) * 1985-03-08 1989-08-31 Ferrosan A/S Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds
DK476885D0 (da) * 1985-10-17 1985-10-17 Ferrosan As Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
AU594676B2 (en) * 1985-05-17 1990-03-15 Novo Nordisk A/S Oxadiazolyl imidazobenaodiazepine compound, pharmaceutical composition containing said compound, method of preparing said compound and method of treating a central nervous system ailment
DE202441T1 (de) * 1985-05-17 1987-03-19 Aktieselskabet Ferrosan, Soeborg Oxadiazolylimidazobenzodiazepine, verfahren zu ihrer herstellung und pharmazeutische zubereitungen.
US4622321A (en) * 1985-05-17 1986-11-11 As Ferrosan Oxadiazolylimidazobenzodiazepine, compositions, and method

Also Published As

Publication number Publication date
FI871615A0 (fi) 1987-04-13
AU588994B2 (en) 1989-09-28
NO164655C (no) 1990-10-31
AU7158387A (en) 1987-10-22
DE3766401D1 (de) 1991-01-10
NZ219915A (en) 1989-04-26
JPS62249985A (ja) 1987-10-30
DE241682T1 (de) 1988-02-25
KR870010052A (ko) 1987-11-30
NO871459L (no) 1987-10-19
EP0241682A2 (de) 1987-10-21
JPH07116195B2 (ja) 1995-12-13
IL82117A (en) 1992-03-29
NO871459D0 (no) 1987-04-07
FI87458C (fi) 1993-01-11
ATE58737T1 (de) 1990-12-15
EP0241682B1 (de) 1990-11-28
ES2037673T3 (es) 1993-07-01
US4772599A (en) 1988-09-20
GR3001160T3 (en) 1992-06-30
KR940009784B1 (ko) 1994-10-17
DK174086D0 (da) 1986-04-16
EP0241682A3 (en) 1988-10-26
PT84690B (pt) 1989-11-30
NO164655B (no) 1990-07-23
IL82117A0 (en) 1987-10-30
FI871615A7 (fi) 1987-10-17
PT84690A (en) 1987-05-01
CA1293724C (en) 1991-12-31
IE60488B1 (en) 1994-07-27
IE870981L (en) 1987-10-16
ZA872630B (en) 1987-10-02
FI87458B (fi) 1992-09-30

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