PH23326A - Novel quinoline derivatives - Google Patents

Novel quinoline derivatives

Info

Publication number
PH23326A
PH23326A PH35178A PH35178A PH23326A PH 23326 A PH23326 A PH 23326A PH 35178 A PH35178 A PH 35178A PH 35178 A PH35178 A PH 35178A PH 23326 A PH23326 A PH 23326A
Authority
PH
Philippines
Prior art keywords
quinoline derivatives
novel quinoline
novel
derivatives
quinoline
Prior art date
Application number
PH35178A
Other languages
English (en)
Inventor
Jun-Ichi Matsumoto
Teruyuki Miyamoto
Hiroshi Egawa
Shinichi Nakamura
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of PH23326A publication Critical patent/PH23326A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PH35178A 1986-04-25 1987-04-24 Novel quinoline derivatives PH23326A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9754386 1986-04-25

Publications (1)

Publication Number Publication Date
PH23326A true PH23326A (en) 1989-07-14

Family

ID=14195155

Family Applications (1)

Application Number Title Priority Date Filing Date
PH35178A PH23326A (en) 1986-04-25 1987-04-24 Novel quinoline derivatives

Country Status (17)

Country Link
US (1) US4886810A (de)
EP (1) EP0242789A3 (de)
JP (1) JP2572591B2 (de)
KR (1) KR870010005A (de)
CN (1) CN87103138A (de)
AU (1) AU7190987A (de)
DD (1) DD263290A5 (de)
DK (1) DK208787A (de)
FI (1) FI871788A7 (de)
HU (1) HU198198B (de)
IL (1) IL82246A0 (de)
NO (1) NO871727L (de)
PH (1) PH23326A (de)
PT (1) PT84749B (de)
SU (3) SU1582986A3 (de)
YU (4) YU73987A (de)
ZA (1) ZA872874B (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822801A (en) * 1984-07-20 1989-04-18 Warner-Lambert Company 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents
IL79189A (en) * 1985-06-26 1990-07-12 Daiichi Seiyaku Co Quinoline and/or naphthyridine-4-oxo-3-carboxylic acid derivatives,process for their preparation and pharmaceutical compositions comprising them
AU594983B2 (en) * 1985-10-29 1990-03-22 Dainippon Pharmaceutical Co. Ltd. Novel quinoline derivatives and processes for preparation thereof
DE3711193A1 (de) * 1987-04-02 1988-10-13 Bayer Ag 5-substituierte chinolon- und naphthyridoncarbonsaeure-derivate
US5591744A (en) * 1987-04-16 1997-01-07 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
IL88003A (en) * 1987-10-16 1992-11-15 Dainippon Pharmaceutical Co Quinoline derivatives,their preparation and pharmaceutical compositions containing them
EP0319906A3 (de) * 1987-12-11 1990-05-02 Dainippon Pharmaceutical Co., Ltd. Chinolinderivate, Verfahren zu ihrer Herstellung und sie enthaltendes antibakterielles Mittel
US4920120A (en) * 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
US5585491A (en) * 1988-01-25 1996-12-17 Otsuka Pharmaceutical Co., Ltd. Antibacterial agents
DE3814517A1 (de) * 1988-02-05 1989-08-17 Bayer Ag Chinolon- und naphthyridoncarbonsaeurederivate, verfahren zu ihrer herstellung und sie enthaltende antibakterielle mittel und futterzusatzstoffe
US5173484A (en) * 1988-02-05 1992-12-22 Bayer Aktiengesellschaft Quinolone- and naphthyridone carboxylic acid derivatives, process for their production, antibacterial compositions and feed additives containing them
AU609974B2 (en) * 1988-05-18 1991-05-09 Warner-Lambert Company Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids
JPH0674261B2 (ja) * 1988-06-21 1994-09-21 塩野義製薬株式会社 キノロンカルボン酸誘導体
WO1991001308A1 (en) * 1989-07-21 1991-02-07 Ss Pharmaceutical Co., Ltd. Quinolonecarboxylic acid derivatives
US5057523A (en) * 1988-09-22 1991-10-15 Abbott Laboratories Dipeptide quinolone derivatives
CA1332605C (en) * 1988-10-03 1994-10-18 Yasuhiro Nishitani Pyridonecarboxylic acids
US5262417A (en) * 1988-12-06 1993-11-16 The Upjohn Company Antibacterial quinolone compounds
ES2019551A6 (es) * 1990-04-11 1991-06-16 Ercros Sa Procedimiento para la obtencion de derivados del acido 6-fluor-1, 4-dihidro-4-oxo-7-piperacinil-3-quinlincarboxilico.
DK0525057T3 (da) 1990-04-18 2000-07-31 Procter & Gamble Pharma Antimikrobielle quinolonyllactamer
DE4019023A1 (de) * 1990-06-14 1991-12-19 Bayer Ag Verfahren zur herstellung von chinolincarbonsaeuren
US5221676A (en) * 1992-02-06 1993-06-22 Warner-Lambert Company 7-substituted quinolones and naphthyridones as antibacterial agents
WO1994014794A1 (fr) * 1992-12-28 1994-07-07 Yoshitomi Pharmaceutical Industries, Ltd. Derive d'acide 8-methoxyquinolonecarboxylique
CA2152828A1 (en) * 1993-03-16 1994-07-07 Shin-Ichi Uesato 8-methoxy-quinolonecarboxylic acid derivatives
TW252107B (de) * 1993-08-27 1995-07-21 Hokuriku Pharmacetical Co Ltd
DE69428206T2 (de) * 1993-10-28 2002-06-13 Kaken Pharmaceutical Co., Ltd. Chinolincarbonsäurederivate und ihre salze
EP0775145A1 (de) * 1994-08-02 1997-05-28 The Procter & Gamble Company Verfahren zur herstellung von quinolonyl laktam antimikorbielle verbindungen und zwischenprodukte
EP0775114B1 (de) * 1994-08-02 2000-03-22 The Procter & Gamble Company Verfahren zur herstellung von antimikrobiellen verbindungen
CN1183778A (zh) * 1995-01-24 1998-06-03 北陆制药株式会社 喹啉羧酸衍生物
ATE228130T1 (de) * 1996-02-23 2002-12-15 Bayer Ag Gegebenenfalls substituierte 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo- 4.3.0)-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3- hinolincarbonsäuren und ihre derivate
AU8038798A (en) * 1997-06-24 1999-01-04 Daiichi Pharmaceutical Co., Ltd. Cis-substituted fluoromethylpyrrolidine derivatives
ATE423776T1 (de) * 1997-09-15 2009-03-15 Procter & Gamble Antimikrobielle chinolone, ihre zusammensetzungen und ihre verwendungen
RU2275361C3 (ru) * 2002-11-20 2021-10-01 Джапан Тобакко Инк. Соединение 4-оксохинолина и его применение в качестве ингибитора вич интегразы
SI1666477T1 (sl) * 2003-09-10 2013-10-30 Kyorin Pharmaceutical Co., Ltd. Derivati 7-(4-substituiran 3-ciklopropilaminometil-1-pirolidinil) kinolonkarboksilne kisline
GB0505969D0 (en) * 2005-03-23 2005-04-27 Novartis Ag Organic compounds
US7563805B2 (en) * 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
JP5063032B2 (ja) * 2005-05-19 2012-10-31 第一三共株式会社 トリ−、テトラ−置換−３−アミノピロリジン誘導体
RU2399616C1 (ru) * 2006-06-23 2010-09-20 Джапан Тобакко Инк. Производное 6-(гетероциклзамещенный бензил)-4-оксохинолина и его применение в качестве ингибитора интегразы вич
PL2097400T3 (pl) 2007-01-05 2013-11-29 Daiichi Sankyo Co Ltd Skondensowane podstawione pochodne aminopirolidyny
US8222407B2 (en) * 2007-05-24 2012-07-17 Kyorin Pharmaceutical Co., Ltd. Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
DE3318145A1 (de) * 1983-05-18 1984-11-22 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
ZA852369B (en) * 1984-04-26 1985-12-24 Abbott Lab Quinoline antibacterial compounds
IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
US4771054A (en) * 1985-01-23 1988-09-13 Warner-Lambert Company Antibacterial agents
US4657913A (en) * 1985-04-18 1987-04-14 Warner-Lambert Company Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
AU594983B2 (en) * 1985-10-29 1990-03-22 Dainippon Pharmaceutical Co. Ltd. Novel quinoline derivatives and processes for preparation thereof
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
US4977154A (en) * 1985-12-12 1990-12-11 Warner-Lambert Company 5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents
US4771055A (en) * 1986-07-28 1988-09-13 Warner-Lambert Company 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acids

Also Published As

Publication number Publication date
JP2572591B2 (ja) 1997-01-16
CN87103138A (zh) 1987-11-04
NO871727D0 (no) 1987-04-24
HU198198B (en) 1989-08-28
SU1588282A3 (ru) 1990-08-23
FI871788A7 (fi) 1987-10-26
DD263290A5 (de) 1988-12-28
ZA872874B (en) 1987-10-12
IL82246A0 (en) 1987-10-30
HUT45520A (en) 1988-07-28
EP0242789A2 (de) 1987-10-28
EP0242789A3 (de) 1990-09-05
US4886810A (en) 1989-12-12
SU1582986A3 (ru) 1990-07-30
PT84749A (en) 1987-05-01
DK208787A (da) 1987-10-26
PT84749B (en) 1989-06-07
SU1588281A3 (ru) 1990-08-23
YU27688A (en) 1988-12-31
DK208787D0 (da) 1987-04-24
JPS6345261A (ja) 1988-02-26
FI871788A0 (fi) 1987-04-23
NO871727L (no) 1987-10-26
YU73987A (en) 1988-08-31
AU7190987A (en) 1987-10-29
YU27788A (en) 1990-04-30
YU27488A (en) 1988-10-31
KR870010005A (ko) 1987-11-30

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