PH25906A - Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)azabicycloalkanes - Google Patents

Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)azabicycloalkanes

Info

Publication number: PH25906A
Authority: PH; Philippines
Prior art keywords: memory; group; correcting; arylthioamido; azabicycloalkanes
Prior art date: 1988-02-01

Application number

PH38133A

Other languages

English (en)

Inventor

William Levi Smith

Original Assignee

Robins Co Inc A H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-02-01

Filing date

1989-01-31

Publication date

1991-12-19

1989-01-31 Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H

1991-12-19 Publication of PH25906A publication Critical patent/PH25906A/en

Links

230000007812 deficiency Effects 0.000 title abstract 2
230000002708 enhancing effect Effects 0.000 title 1
-1 methoxy-1H-benzotriazolyl Chemical group 0.000 abstract 3
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000005871 1,3-benzodioxolyl group Chemical group 0.000 abstract 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
239000005864 Sulphur Chemical group 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
230000037396 body weight Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000002541 furyl group Chemical group 0.000 abstract 1
150000004677 hydrates Chemical class 0.000 abstract 1
125000003387 indolinyl group Chemical group N1(CCC2=CC=CC=C12)* 0.000 abstract 1
125000001624 naphthyl group Chemical group 0.000 abstract 1
230000003287 optical effect Effects 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C33/00—Moulds or cores; Details thereof or accessories therefor
- B29C33/44—Moulds or cores; Details thereof or accessories therefor with means for, or specially constructed to facilitate, the removal of articles, e.g. of undercut articles

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Mechanical Engineering (AREA)
Neurology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)
Indole Compounds (AREA)

PH38133A 1988-02-01 1989-01-31 Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)azabicycloalkanes PH25906A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/150,981 US4863919A (en)	1988-02-01	1988-02-01	Method of enhancing memory or correcting memory deficiency with arylamido(and arylthiomido)-azabicycloalkanes

Publications (1)

Publication Number	Publication Date
PH25906A true PH25906A (en)	1991-12-19

Family

ID=22536826

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH38133A PH25906A (en)	1988-02-01	1989-01-31	Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)azabicycloalkanes

Country Status (16)

Country	Link
US (1)	US4863919A (de)
EP (1)	EP0327335B1 (de)
JP (1)	JPH01226818A (de)
KR (1)	KR890012649A (de)
AT (1)	ATE81457T1 (de)
AU (1)	AU629197B2 (de)
CA (1)	CA1320448C (de)
DE (1)	DE68903178T2 (de)
DK (1)	DK42589A (de)
ES (1)	ES2045402T3 (de)
GR (1)	GR3006764T3 (de)
IL (1)	IL88434A (de)
NZ (1)	NZ227794A (de)
PH (1)	PH25906A (de)
PT (1)	PT89575B (de)
ZA (1)	ZA889109B (de)

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AU654013B2 (en) *	1991-03-13	1994-10-20	Regents Of The University Of Minnesota	2-hydroxy-3(4-iodophenyl)-1-(4-phenylpiperidinyl) propane
US5723103A (en) *	1994-12-09	1998-03-03	Vanderbilt University	Substituted benzamides and radioligand analogs and methods of use
SE0000540D0 (sv) *	2000-02-18	2000-02-18	Astrazeneca Ab	New compounds
AU2001284645A1 (en) *	2000-08-18	2002-03-04	Pharmacia And Upjohn Company	Quinuclidine-substituted aryl compounds for treatment of disease
US6492385B2 (en)	2000-08-18	2002-12-10	Pharmacia & Upjohn Company	Quinuclidine-substituted heteroaryl moieties for treatment of disease
AU2001282873A1 (en) *	2000-08-18	2002-03-04	Pharmacia And Upjohn Company	Quinuclidine-substituted aryl compounds for treatment of disease
US6479510B2 (en) *	2000-08-18	2002-11-12	Pharmacia & Upjohn Company	Quinuclidine-substituted aryl compounds for treatment of disease
AU2001284646A1 (en) *	2000-08-21	2002-03-04	Pharmacia And Upjohn Company	Quinuclidine-substituted heteroaryl moieties for treatment of disease
WO2002016355A2 (en) *	2000-08-21	2002-02-28	Pharmacia & Upjohn Company	Quinuclidine-substituted heteroaryl moieties for treatment of disease (nicotinic) acetylcholine receptor ligands
US6500840B2 (en)	2000-08-21	2002-12-31	Pharmacia & Upjohn Company	Quinuclidine-substituted heteroaryl moieties for treatment of disease
PE20021019A1 (es)	2001-04-19	2002-11-13	Upjohn Co	Grupos azabiciclicos sustituidos
AR036041A1 (es) *	2001-06-12	2004-08-04	Upjohn Co	Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
AR036040A1 (es)	2001-06-12	2004-08-04	Upjohn Co	Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
EP1453828A2 (de) *	2001-10-16	2004-09-08	AstraZeneca AB	Azabicyclische verbindungen zur behandlung des fibromyalgie-syndroms
US6849620B2 (en)	2001-10-26	2005-02-01	Pfizer Inc	N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease
WO2003037896A1 (en) *	2001-10-26	2003-05-08	Pharmacia & Upjohn Company	N-azabicyclo-substituted hetero-bicyclic carboxamides as nachr agonists
MXPA04004464A (es) *	2001-11-08	2004-08-11	Upjohn Co	Compuestos de heteroarilo sustituido con azabiciclo para el tratamiento de enfermedades.
DE10156719A1 (de)	2001-11-19	2003-05-28	Bayer Ag	Heteroarylcarbonsäureamide
DE10164139A1 (de)	2001-12-27	2003-07-10	Bayer Ag	2-Heteroarylcarbonsäureamide
US6852716B2 (en) *	2002-02-15	2005-02-08	Pfizer Inc	Substituted-aryl compounds for treatment of disease
WO2003070731A2 (en) *	2002-02-19	2003-08-28	Pharmacia & Upjohn Company	Azabicyclic compounds for the treatment of disease
EP1478646A1 (de) *	2002-02-20	2004-11-24	PHARMACIA & UPJOHN COMPANY	Azabicyclische verbindungen mit activität an alfa7 nikotinischen acetylcholin rezeptoren
US7176198B2 (en)	2002-08-01	2007-02-13	Pfizer Inc.	1H-pyrazole and 1H-pyrrole-azabicyclic compounds for the treatment of disease
JP2006506395A (ja) *	2002-11-01	2006-02-23	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	ＣＮＳ疾患の治療のための、α７ニコチンアゴニスト活性及び５ＨＴ３アンタゴニスト活性を有する化合物
EA200501715A1 (ru)	2003-04-30	2006-06-30	ДЗЕ ИНСТИТЬЮТС ФОР ФАРМАСЬЮТИКАЛ ДИСКАВЕРИ, ЭлЭлСи	Замещённые аминокарбоновые кислоты в качестве ингибиторов протеинтирозинфосфатазы-1в
WO2006055725A2 (en)	2004-11-18	2006-05-26	The Institutes For Pharmaceutical Discovery, Llc	Substituted amino acids as protein tyrosine phosphatase inhibitors
US20080242688A1 (en) *	2007-03-19	2008-10-02	Astrazeneca Ab	Method 741
US8435762B2 (en)	2008-10-09	2013-05-07	Howard Hughes Medical Institute	Chimeric ligand-gated ion channels and methods of use thereof
CN105687190A (zh)	2008-11-19	2016-06-22	福拉姆医药股份有限公司	用(R)-7-氯-N-(奎宁环-3-基)苯并[b]噻吩-2-甲酰胺及其可药用盐治疗认知障碍
KR20180101641A (ko)	2010-05-17	2018-09-12	포럼 파마슈티칼즈 인크.	(R)-7-클로로-N-(퀴누클리딘-3-일)벤조[b]티오펜-2-카르복사미드 히드로클로리드 모노히드레이트의 결정질 형태
TWI589576B (zh)	2011-07-15	2017-07-01	諾華公司	氮雜－雙環二芳基醚之鹽類及製造彼等或其前驅物之方法
EP3461481A1 (de)	2012-05-08	2019-04-03	Forum Pharmaceuticals Inc.	Verfahren zur aufrechterhaltung, behandlung oder verbesserung der kognitiven funktion
EP3233087B1 (de)	2014-12-16	2019-10-02	Axovant Sciences GmbH	Geminale substituierte chinuklidinamidverbindungen als agonisten von alpha-7-nikotinischen acetylcholinrezeptoren
JP2018516973A (ja)	2015-06-10	2018-06-28	フォーラム・ファーマシューティカルズ・インコーポレイテッドＦｏｒｕｍＰｈａｒｍａｃｅｕｔｉｃａｌｓＩｎｃ．	α７−ニコチン性アセチルコリン受容体のアゴニストとしてのアミノベンゾイソオキサゾール化合物
WO2017027600A1 (en)	2015-08-12	2017-02-16	Forum Pharmaceuticals, Inc.	GEMINAL SUBSTITUTED AMINOBENZISOXAZOLE COMPOUNDS AS AGONISTS OF α7-NICOTINIC ACETYLCHOLINE RECEPTORS

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GB1593146A (en) *	1976-11-05	1981-07-15	Beecham Group Ltd	Octahydro-quinolizinyl benzamide derivatives
EP0067565A1 (de) *	1981-06-16	1982-12-22	Beecham Group Plc	Bicyclische Benzamide, Verfahren zu ihrer Herstellung und ihre Verwendung
FR2531083B1 (fr) *	1982-06-29	1986-11-28	Sandoz Sa	Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
FR2529548A1 (fr) *	1982-07-02	1984-01-06	Delalande Sa	Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique
US4593034A (en) *	1984-04-06	1986-06-03	A. H. Robins Company, Inc.	2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenzamides
DE3446484A1 (de) *	1984-12-20	1986-07-03	Sandoz-Patent-GmbH, 7850 Lörrach	Therapeutische verwendung von benzoesaeurepiperidylestern oder -amiden
US4605652A (en) *	1985-02-04	1986-08-12	A. H. Robins Company, Inc.	Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)-azabicycloalkanes
US4870181A (en) *	1985-02-04	1989-09-26	A. H. Robins Company, Incorporated	Process for the preparation of 2-alkoxy-N-(1-azabicyclo[2.2.2])octan-3-yl)aminobenzamides
DE3688296T2 (de) *	1985-03-14	1993-11-04	Beecham Group Plc	Arzneimittel zur behandlung von erbrechen.
GB8511988D0 (en) *	1985-05-11	1985-06-19	Beecham Group Plc	Compounds
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1988
- 1988-02-01 US US07/150,981 patent/US4863919A/en not_active Expired - Fee Related
- 1988-11-21 IL IL88434A patent/IL88434A/xx not_active IP Right Cessation
- 1988-12-05 ZA ZA889109A patent/ZA889109B/xx unknown
1989
- 1989-01-23 JP JP1013894A patent/JPH01226818A/ja active Pending
- 1989-01-26 CA CA000589194A patent/CA1320448C/en not_active Expired - Fee Related
- 1989-01-30 NZ NZ227794A patent/NZ227794A/en unknown
- 1989-01-31 PT PT89575A patent/PT89575B/pt active IP Right Grant
- 1989-01-31 DK DK042589A patent/DK42589A/da not_active Application Discontinuation
- 1989-01-31 PH PH38133A patent/PH25906A/en unknown
- 1989-01-31 KR KR1019890001079A patent/KR890012649A/ko not_active Ceased
- 1989-02-01 ES ES89300961T patent/ES2045402T3/es not_active Expired - Lifetime
- 1989-02-01 AT AT89300961T patent/ATE81457T1/de not_active IP Right Cessation
- 1989-02-01 EP EP89300961A patent/EP0327335B1/de not_active Expired - Lifetime
- 1989-02-01 AU AU29506/89A patent/AU629197B2/en not_active Ceased
- 1989-02-01 DE DE8989300961T patent/DE68903178T2/de not_active Expired - Fee Related
1993
- 1993-01-11 GR GR930400020T patent/GR3006764T3/el unknown

Also Published As

Publication number	Publication date
ZA889109B (en)	1989-08-30
DK42589D0 (da)	1989-01-31
CA1320448C (en)	1993-07-20
PT89575B (pt)	1994-01-31
ATE81457T1 (de)	1992-10-15
EP0327335A1 (de)	1989-08-09
IL88434A (en)	1992-09-06
AU2950689A (en)	1989-08-03
DK42589A (da)	1989-08-02
JPH01226818A (ja)	1989-09-11
DE68903178T2 (de)	1993-03-18
EP0327335B1 (de)	1992-10-14
PT89575A (pt)	1989-10-04
NZ227794A (en)	1991-12-23
US4863919A (en)	1989-09-05
ES2045402T3 (es)	1994-01-16
IL88434A0 (en)	1989-06-30
GR3006764T3 (de)	1993-06-30
DE68903178D1 (de)	1992-11-19
AU629197B2 (en)	1992-10-01
KR890012649A (ko)	1989-09-18

Publication	Publication Date	Title
PH25906A (en)	1991-12-19	Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)azabicycloalkanes
EP0190920A3 (en)	1990-04-18	Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)azabicycloalkanes
AU569983B2 (en)	1988-02-25	Xanthine derivatives
ZA882418B (en)	1989-12-27	1-phenyl-3-naphthalenyloxypropanamines
IL110151A0 (en)	1994-10-07	Amide and urea derivatives and pharmaceutical compositions containing the same
PH25859A (en)	1991-12-02	Composition for treatment of ischemic disorder
EA200000614A1 (ru)	2001-02-26	2,3-замещенные соединения индола в качестве ингибиторов сох-2
ZA894508B (en)	1990-03-28	Pharmaceutical compounds
IL85725A (en)	1991-12-12	Imidazole derivatives,their manufacture and pharmaceutical compositions containing them
GR852040B (de)	1985-12-19
DE3661311D1 (en)	1989-01-05	Novel guanidinomethylcyclohexancarboxylic acid compounds, processes for preparing them, and pharmaceutical compositions containing them
HUT75647A (en)	1997-05-28	Imidazolidinone derivatives and pharmaceutical compositions containing them, which are suitable for treament of senile dementia
DK0570850T3 (da)	1997-06-16	Benzo(b)thiophen-3-yl-piperaziner, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler
ZA884697B (en)	1989-03-29	Treating agent for heart failure
AU563426B2 (en)	1987-07-09	3-alkoxy-2(n-pyrrolidino)-n-pyridyl-n-furyl (or thienyl) methyl propylamines
ES8401957A1 (es)	1984-01-01	Procedimiento de preparacion de derivados del acido 2-tiofen-acetico.
EP0301466A3 (en)	1990-09-12	Uricosuric composition
AU7384381A (en)	1982-02-18	Substituted oxadiazoles