PH26255A - Macrocyclic chelating agents and chelates thereof - Google Patents

Macrocyclic chelating agents and chelates thereof Download PDF

Info

Publication number
PH26255A
PH26255A PH37968A PH37968A PH26255A PH 26255 A PH26255 A PH 26255A PH 37968 A PH37968 A PH 37968A PH 37968 A PH37968 A PH 37968A PH 26255 A PH26255 A PH 26255A
Authority
PH
Philippines
Prior art keywords
methylglucamine
chelate complexes
corresponding salts
acid
tetraaza
Prior art date
Application number
PH37968A
Other languages
English (en)
Inventor
Ernest H Felder
Carlo M Musu
Luciano G Fumagalli
Fulvio M E Uggeri
Original Assignee
Bracco Ind Chimica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Ind Chimica Spa filed Critical Bracco Ind Chimica Spa
Publication of PH26255A publication Critical patent/PH26255A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PH37968A 1987-12-24 1988-12-22 Macrocyclic chelating agents and chelates thereof PH26255A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23217/87A IT1224416B (it) 1987-12-24 1987-12-24 Chelanti macrociclici e loro chelati

Publications (1)

Publication Number Publication Date
PH26255A true PH26255A (en) 1992-04-01

Family

ID=11204998

Family Applications (1)

Application Number Title Priority Date Filing Date
PH37968A PH26255A (en) 1987-12-24 1988-12-22 Macrocyclic chelating agents and chelates thereof

Country Status (14)

Country Link
EP (2) EP0325762B1 (ja)
JP (1) JP2744920B2 (ja)
KR (1) KR900700467A (ja)
AT (1) ATE120191T1 (ja)
DE (1) DE3853415T2 (ja)
ES (1) ES2070845T3 (ja)
IE (1) IE67551B1 (ja)
IL (1) IL88762A (ja)
IT (1) IT1224416B (ja)
MX (1) MX9203262A (ja)
NZ (1) NZ227421A (ja)
PH (1) PH26255A (ja)
WO (1) WO1989005802A1 (ja)
ZA (1) ZA889597B (ja)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3869251D1 (de) * 1987-07-16 1992-04-23 Nycomed As Aminopolycarbonsaeure und ihre derivate.
DE4001655A1 (de) 1990-01-18 1991-07-25 Schering Ag 6-ring enthaltende makrocyclische tetraaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
US6039931A (en) * 1989-06-30 2000-03-21 Schering Aktiengesellschaft Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production
US5695739A (en) * 1989-06-30 1997-12-09 Schering Aktiengesellschaft Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production
DE4009119A1 (de) * 1990-03-19 1991-09-26 Schering Ag 1,4,7,10-tetraazacyclododecan-butyltriole, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
US5162109A (en) * 1990-09-13 1992-11-10 Mallinckrodt Medical, Inc. Magnetic resonance imaging agents
DE4035760A1 (de) * 1990-11-08 1992-05-14 Schering Ag Mono-n-substituierte 1,4,7,10-tetraazacyclododecan-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
US6875864B2 (en) 1991-08-01 2005-04-05 Bracco International B.V. Aminocarboxylate ligands having substituted aromatic amide moieties
EP0565930A1 (en) * 1992-03-27 1993-10-20 Nihon Medi-Physics Co., Ltd. Tetraazacyclododecane tetraacetic acid derivatives and the use thereof as diagnostic agents
US5310535A (en) * 1992-04-24 1994-05-10 The Dow Chemical Company Carboxamide modified polyamine chelators and radioactive complexes thereof for conjugation to antibodies
EP0588229A3 (en) * 1992-09-12 1994-06-15 Hoechst Ag Macrocyclic chelating agents for the preparation of technetium or rhenium complexes
WO1995001346A1 (en) * 1993-06-30 1995-01-12 Akzo Nobel N.V. Chelating compounds
JP3878208B2 (ja) * 1994-04-08 2007-02-07 ブラッコ インターナショナル ベスローテン フェンノートシャップ 芳香族アミド化合物およびそれらのキレート
US6693190B1 (en) 1994-05-11 2004-02-17 Bracco International B.V. Enhanced relaxivity monomeric and multimeric compounds
IT1274038B (it) * 1994-07-29 1997-07-14 Bracco Spa Chelanti macrociclici loro chelati e relativi usi in campo diagnostico
US5672335A (en) * 1994-11-30 1997-09-30 Schering Aktiengesellschaft Use of metal complexes as liver and gallbladder X-ray diagnostic agents
DE19507820A1 (de) * 1995-02-21 1996-08-22 Schering Ag Neuartig substituierte DTPA-Derivate, deren Metallkomplexe, diese Komplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Diagnostik, sowie Verfahren zur Herstellung der Komplexe und Mittel
IT1291624B1 (it) * 1997-04-18 1999-01-11 Bracco Spa Chelati complessi di metalli paramagnetici a bassa tossicita'
IT1293777B1 (it) * 1997-07-25 1999-03-10 Bracco Spa Processo per la preparazione di tetraazamacrocicli
IT1293778B1 (it) * 1997-07-25 1999-03-10 Bracco Spa 1,4,7,10-tetraazabiciclo(8.2.2.)tetradecan-2 one, sua preparazione e suo uso per la preparazione di tetraazamacrocicli
US6495118B1 (en) 1997-09-26 2002-12-17 Schering Aktiengesellschaft Lipophilic metal complexes for necrosis and infarction imaging
DE19744004C1 (de) * 1997-09-26 1999-07-22 Schering Ag Lipophile Metall-Komplexe für Nekrose und Infarkt-Imaging
IT1297034B1 (it) * 1997-12-30 1999-08-03 Bracco Spa Acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico
IT1297035B1 (it) 1997-12-30 1999-08-03 Bracco Spa Derivati dell'acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL194579C (nl) * 1983-01-21 2002-08-05 Schering Ag Diagnostisch middel.
DE3316703A1 (de) * 1983-05-04 1984-11-08 Schering AG, 1000 Berlin und 4709 Bergkamen Orales kontrastmittel fuer die kernspintomographie und dessen herstellung
US4639365A (en) * 1984-10-18 1987-01-27 The Board Of Regents, The University Of Texas System Gadolinium chelates as NMR contrast agents
DE3772785D1 (de) * 1986-01-23 1991-10-17 Squibb & Sons Inc 1-substituiertes-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecan und analoga.
FR2596992B1 (fr) * 1986-04-11 1988-12-16 Guerbet Sa Sel de lysine du complexe gadolinium-dota et ses applications au diagnostic
DE3625417C2 (de) * 1986-07-28 1998-10-08 Schering Ag Tetraazacyclododecan-Derivate
DE3851070T3 (de) * 1987-02-28 2006-12-28 Sumitomo Electric Industries, Ltd. Verfahren zur Herstellung eines Oxid-Verbindungssupraleiterfadens.
EP0505015B1 (en) * 1987-03-13 1997-05-14 Kabushiki Kaisha Toshiba Superconducting wire and method of manufacturing the same

Also Published As

Publication number Publication date
IE883844L (en) 1989-06-24
IL88762A (en) 1995-07-31
EP0325762A1 (en) 1989-08-02
MX9203262A (es) 1992-07-01
DE3853415T2 (de) 1995-08-31
EP0440606A1 (en) 1991-08-14
IE67551B1 (en) 1996-04-17
IT8723217A0 (it) 1987-12-24
ES2070845T3 (es) 1995-06-16
JP2744920B2 (ja) 1998-04-28
KR900700467A (ko) 1990-08-13
IL88762A0 (en) 1989-07-31
ATE120191T1 (de) 1995-04-15
JPH03501848A (ja) 1991-04-25
NZ227421A (en) 1990-10-26
IT1224416B (it) 1990-10-04
DE3853415D1 (de) 1995-04-27
ZA889597B (en) 1989-09-27
WO1989005802A1 (en) 1989-06-29
EP0325762B1 (en) 1995-03-22

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