PH26380A - The use of 3'-deoxythymidin-2'-ene-2',3-didehydro-thymidine) in treating patients infected with retroviruses - Google Patents

The use of 3'-deoxythymidin-2'-ene-2',3-didehydro-thymidine) in treating patients infected with retroviruses Download PDF

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Publication number
PH26380A
PH26380A PH35869A PH35869A PH26380A PH 26380 A PH26380 A PH 26380A PH 35869 A PH35869 A PH 35869A PH 35869 A PH35869 A PH 35869A PH 26380 A PH26380 A PH 26380A
Authority
PH
Philippines
Prior art keywords
ene
deoxythymidin
retrovirus
diluent
admixture
Prior art date
Application number
PH35869A
Other languages
English (en)
Inventor
Tai-Shun Lin
William H Prusoff
Original Assignee
Univ Yale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25478432&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PH26380(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Yale filed Critical Univ Yale
Publication of PH26380A publication Critical patent/PH26380A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
PH35869A 1986-12-17 1987-09-29 The use of 3'-deoxythymidin-2'-ene-2',3-didehydro-thymidine) in treating patients infected with retroviruses PH26380A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/942,666 US4978655A (en) 1986-12-17 1986-12-17 Use of 3'-deoxythymidin-2'-ene (3'deoxy-2',3'-didehydrothymidine) in treating patients infected with retroviruses

Publications (1)

Publication Number Publication Date
PH26380A true PH26380A (en) 1992-06-01

Family

ID=25478432

Family Applications (1)

Application Number Title Priority Date Filing Date
PH35869A PH26380A (en) 1986-12-17 1987-09-29 The use of 3'-deoxythymidin-2'-ene-2',3-didehydro-thymidine) in treating patients infected with retroviruses

Country Status (22)

Country Link
US (1) US4978655A (fr)
EP (1) EP0273277B1 (fr)
JP (1) JPH07116041B2 (fr)
KR (1) KR960000433B1 (fr)
AT (1) ATE77554T1 (fr)
AU (1) AU593405B2 (fr)
CA (1) CA1293447C (fr)
DE (1) DE3780016T2 (fr)
DK (1) DK174627B1 (fr)
EG (1) EG19157A (fr)
ES (1) ES2038650T3 (fr)
FI (1) FI875544A7 (fr)
GR (1) GR3005691T3 (fr)
HK (1) HK55896A (fr)
IE (1) IE60866B1 (fr)
IL (1) IL84790A (fr)
LU (1) LU88822I2 (fr)
NL (1) NL960024I2 (fr)
NZ (1) NZ222935A (fr)
PH (1) PH26380A (fr)
PT (1) PT86346B (fr)
ZA (1) ZA877171B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631370A (en) 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
US5175292A (en) * 1988-01-20 1992-12-29 Regents Of The University Of Minnesota Intermediates for the preparation of dideoxycarbocyclic nucleosides
US6207650B1 (en) 1989-05-15 2001-03-27 Bristol-Myers Squibb Company Antiviral, highly water soluble, stable, crystalline salts of 2′, 3′-dideoxyinosine, 2′, 3′-dideoxy-2′, 3′-didehydrothymidine and 2′, 3′-dideoxy-2′-fluoroinosine
FI95269C (fi) * 1989-05-15 1996-01-10 Squibb Bristol Myers Co 2',3'-dideoksi-inosiinimonohydraatin, 2',3'-dideoksi-2',3'-didehydrot ymidiinimonohydraatin ja 2',3'-dideoksi-2'-fluori-inosiinihemihydraatin antiviraalisia, hyvin vesiliukoisia, stabiileja, kiteisiä suoloja
US5608048A (en) * 1995-06-05 1997-03-04 Bristol-Myers Squibb Company d4 T polymorphic Form 1 process
US5840711A (en) * 1995-06-21 1998-11-24 University Of Kentucky Research Foundation Compositions containing lithium inorganic salts and anti-viral drugs and method of treating viral infections such as acquired immunodeficiency syndrome
CA2189097A1 (fr) 1995-11-15 1997-05-16 Pin-Fang Lin Composition et methode pour le traitement de l'infection retrovirale
US5719132A (en) * 1996-06-27 1998-02-17 Bristol-Myers Squibb Company Compositions and methods of treating HIV with d4T, 5-fluorouracil/tegafur, and uracil
WO2000016625A1 (fr) * 1998-09-23 2000-03-30 University Of Kentucky Research Foundation Compositions medicamenteuses antivirales contenant des sels inorganiques de lithium
BR0109602A (pt) * 2000-03-30 2004-06-29 Bristol Myers Squibb Co Glóbulos de liberação controlada contendo estavudina
EP2316468A1 (fr) 2002-02-22 2011-05-04 Shire LLC Système de distribution et méthodes de protection et d'administration de dextroamphetamine
CN102174038A (zh) * 2003-02-19 2011-09-07 耶鲁大学 用于治疗病毒感染的抗病毒核苷
US20040200730A1 (en) * 2003-04-14 2004-10-14 Kyo Jibiki Hydrometallurgical copper recovery process
AU2005330489B2 (en) 2004-07-27 2011-08-25 Gilead Sciences, Inc. Nucleoside phosphonate conjugates as anti HIV agents
AU2006286314A1 (en) * 2005-08-31 2007-03-08 Cipla Limited Pharmaceutical combinations containing lamivudine, stavudine and nevirapine
RS53347B (sr) 2008-12-09 2014-10-31 Gilead Sciences, Inc. Modulatori toll-sličnih receptora
US20110223131A1 (en) 2010-02-24 2011-09-15 Gilead Sciences, Inc. Antiviral compounds
WO2016001907A1 (fr) 2014-07-02 2016-01-07 Prendergast Patrick T Mogroside iv et mogroside v utilisables en tant qu'agonistes/stimulateurs/agents de déblocage des récepteurs toll 4 et adjuvant destiné à être utilisé dans un vaccin humain/animal et pour stimuler l'immunité contre des agents pathologiques
JP6522732B2 (ja) 2014-07-11 2019-05-29 ギリアード サイエンシーズ， インコーポレイテッド Ｈｉｖを治療するためのトール様受容体の調節因子
CA2997955A1 (fr) 2015-09-15 2017-03-23 Gilead Sciences, Inc. Modulateurs de recepteurs de type toll pour le traitement du vih

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3322747A (en) * 1965-04-01 1967-05-30 Merck & Co Inc Thionocarbonate nucleosides
US3817982A (en) * 1971-12-29 1974-06-18 Syntex Inc 2{40 ,3{40 -unsaturated nucleosides and method of making
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
JPS5943550B2 (ja) * 1975-08-29 1984-10-23 田辺製薬株式会社 不飽和ヌクレオシドの製法
DE3515870A1 (de) * 1985-05-03 1986-11-06 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 5-fluortoluol-2,4-disulfochlorid
US4710492A (en) * 1986-06-23 1987-12-01 Yale University 3'-azido-2',3'-dideoxy-5-halouridine and its use in treating patients infected with retroviruses
NL8700089A (nl) * 1987-01-15 1988-08-01 Stichting Rega V Z W Therapeutische toepassing van dideoxythymidine en dideoxythymidineen.
DE3806633A1 (de) * 1987-09-01 1989-03-09 Bayer Ag Antivirales mittel
JP2648329B2 (ja) * 1987-09-18 1997-08-27 エフ・ホフマン−ラ ロシュ アーゲー エイズの予防または治療用医薬組成物
SE8704298D0 (sv) * 1987-11-03 1987-11-03 Astra Ab Compounds for use in therapy
JPH0227782A (ja) * 1988-07-15 1990-01-30 Hikari Gijutsu Kenkyu Kaihatsu Kk 半導体発光素子
JPH0438727A (ja) * 1990-06-04 1992-02-07 Sharp Corp 光学式ピックアップ装置の対物レンズ塵埃付着防止機構

Also Published As

Publication number Publication date
ATE77554T1 (de) 1992-07-15
EP0273277A3 (en) 1989-09-13
IL84790A0 (en) 1988-05-31
DK557087D0 (da) 1987-10-23
NL960024I2 (nl) 1997-06-02
JPH07116041B2 (ja) 1995-12-13
PT86346B (pt) 1990-11-07
FI875544A0 (fi) 1987-12-16
GR3005691T3 (fr) 1993-06-07
NL960024I1 (nl) 1996-12-02
IL84790A (en) 1993-03-15
LU88822I2 (fr) 1997-01-06
CA1293447C (fr) 1991-12-24
DE3780016D1 (de) 1992-07-30
IE60866B1 (en) 1994-08-24
ZA877171B (en) 1988-03-24
ES2038650T3 (es) 1993-08-01
EP0273277A2 (fr) 1988-07-06
FI875544L (fi) 1988-06-18
PT86346A (en) 1988-01-01
AU8090087A (en) 1988-06-23
HK55896A (en) 1996-04-03
DK557087A (da) 1988-06-18
AU593405B2 (en) 1990-02-08
FI875544A7 (fi) 1988-06-18
DE3780016T2 (de) 1992-12-24
US4978655A (en) 1990-12-18
IE873245L (en) 1988-06-17
NZ222935A (en) 1990-09-26
KR960000433B1 (ko) 1996-01-06
EP0273277B1 (fr) 1992-06-24
EG19157A (en) 1994-09-29
JPS63215632A (ja) 1988-09-08
DK174627B1 (da) 2003-07-28
KR880007079A (ko) 1988-08-26

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