PH27515A - Water soluble preparations of coccidiostats - Google Patents
Water soluble preparations of coccidiostatsInfo
- Publication number
- PH27515A PH27515A PH38564A PH38564A PH27515A PH 27515 A PH27515 A PH 27515A PH 38564 A PH38564 A PH 38564A PH 38564 A PH38564 A PH 38564A PH 27515 A PH27515 A PH 27515A
- Authority
- PH
- Philippines
- Prior art keywords
- alkyl
- hydrogen
- water
- independently
- preparation
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title abstract 3
- 239000003224 coccidiostatic agent Substances 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 5
- -1 cyano, thiocyanato Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 208000003495 Coccidiosis Diseases 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 206010023076 Isosporiasis Diseases 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000000129 anionic group Chemical group 0.000 abstract 1
- 239000003945 anionic surfactant Substances 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 239000003651 drinking water Substances 0.000 abstract 1
- 235000020188 drinking water Nutrition 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 244000144972 livestock Species 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Polymers & Plastics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Detergent Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Cosmetics (AREA)
- Light Receiving Elements (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Active substance preparations characterised by a) up to 10000 ppm, based on the weight of the preparation, of one or more coccidiostats of the general formulae I and II <IMAGE> in which R<1>, R and R' are, independently of one another, hydrogen or C1-C4-alkyl, R<2> is together with R<3> a double bond or independently thereof hydrogen or C1-C4-alkyl, R<3> is together with R<2> a double bond or independently thereof hydrogen or C1-C4-alkyl, W is oxygen or sulphur, X is, in each case independently of one another, halogen such as fluorine, chlorine and bromine, C1-C4-alkyl, trifluoromethyl, cyano, thiocyanato, C1-C4-alkylthio, nitro or C1-C4-alkoxy, n is 0, 1, 2, 3 or 4, preferably 0 to 2, Y is hydrogen, C1-C6-alkyl, C1-C6-halogenoalkyl, benzyl, phenyl or phenyl which is substituted by at least one radical from the group comprising alkyl, alkoxy, halogenoalkyl, halogenoalkoxy, halogen, alkylthio, alkylsulphinyl, alkylsulphonyl, halogenoalkylthio, halogenoalkylsulphinyl and halogenoalkylsulphonyl, each with 1 to 4 C atoms in the alkyl radical, or is thienyl or halothienyl and Z is a direct bond or a divalent group of the formula O, S, SO, SO2, NH, NR<0> in which R<0> is hydrogen or C1-C4-alkyl, or C(CN)(R<+>) in which R<+> is hydrogen or methyl, b) a water-miscible, physiologically acceptable, anionic or non-ionic surfactant or a mixture of a plurality of these surfactants and c) 0 to 80% by weight, based on the preparation, of a physiologically acceptable, water-soluble organic solvent and d) 0 to 70% by weight, based on the preparation, of water, are suitable, by reason of their solubility in water, for the treatment of coccidiosis in livestock via the drinking water thereof.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3814323A DE3814323A1 (en) | 1988-04-28 | 1988-04-28 | WATER-SOLUBLE PREPARATIONS BY COCCIDIOSTATICA |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH27515A true PH27515A (en) | 1993-08-18 |
Family
ID=6353066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH38564A PH27515A (en) | 1988-04-28 | 1989-04-26 | Water soluble preparations of coccidiostats |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0339555B1 (en) |
| JP (1) | JPH01313430A (en) |
| KR (1) | KR900015740A (en) |
| AT (1) | ATE83661T1 (en) |
| AU (1) | AU619004B2 (en) |
| BG (1) | BG60542B2 (en) |
| BR (1) | BR8901913A (en) |
| DD (1) | DD283773A5 (en) |
| DE (2) | DE3814323A1 (en) |
| DK (1) | DK204689A (en) |
| ES (1) | ES2043934T3 (en) |
| HU (1) | HU205716B (en) |
| IL (1) | IL90098A (en) |
| NZ (1) | NZ228898A (en) |
| PH (1) | PH27515A (en) |
| PL (1) | PL279153A1 (en) |
| PT (1) | PT90387B (en) |
| RU (1) | RU1780510C (en) |
| ZA (1) | ZA893077B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3288132B2 (en) * | 1992-06-25 | 2002-06-04 | サントリー株式会社 | Substituted 1,2,4-triazine-3,5-dione and anticoccidial composition containing the same as an active ingredient |
| US11352332B2 (en) | 2018-02-26 | 2022-06-07 | AlzeCure Pharma AB | Triazine derivatives for treating diseases relating to neurotrophins |
| GB201810668D0 (en) | 2018-06-28 | 2018-08-15 | Stiftelsen Alzecure | New compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3361627A (en) * | 1958-06-20 | 1968-01-02 | Harris Trust And Savings Bank | Phenothiazine compositions |
| DE3300793A1 (en) * | 1983-01-12 | 1984-07-12 | Bayer Ag, 5090 Leverkusen | Coccidiosis |
| DE3408924A1 (en) * | 1984-03-12 | 1985-09-26 | Hoechst Ag, 6230 Frankfurt | SUBSTITUTED 2-PHENYL-HEXAHYDRO-1,2,4-TRIAZINE-3,5-DIONE, METHOD FOR THE PRODUCTION THEREOF, MEANS CONTAINING IT AND THEIR USE |
| EP0179583A1 (en) * | 1984-10-04 | 1986-04-30 | Merck & Co. Inc. | A system for enhancing the water dissolution rate and solubility of poorly soluble drugs |
| DE3531919A1 (en) * | 1985-09-07 | 1987-03-19 | Hoechst Ag | SUBSTITUTED 2-PHENYL-HEXAHYDRO-1,2,4-TRIAZINE-3,5-DIONE, METHOD FOR THE PRODUCTION THEREOF, MEANS CONTAINING IT AND THEIR USE |
-
1988
- 1988-04-28 DE DE3814323A patent/DE3814323A1/en not_active Withdrawn
-
1989
- 1989-04-21 BR BR898901913A patent/BR8901913A/en not_active Application Discontinuation
- 1989-04-24 BG BG088223A patent/BG60542B2/en unknown
- 1989-04-25 DE DE8989107413T patent/DE58903076D1/en not_active Expired - Fee Related
- 1989-04-25 AT AT89107413T patent/ATE83661T1/en not_active IP Right Cessation
- 1989-04-25 ES ES89107413T patent/ES2043934T3/en not_active Expired - Lifetime
- 1989-04-25 EP EP89107413A patent/EP0339555B1/en not_active Expired - Lifetime
- 1989-04-26 ZA ZA893077A patent/ZA893077B/en unknown
- 1989-04-26 NZ NZ228898A patent/NZ228898A/en unknown
- 1989-04-26 KR KR1019890005474A patent/KR900015740A/en not_active Ceased
- 1989-04-26 PH PH38564A patent/PH27515A/en unknown
- 1989-04-26 DD DD89327990A patent/DD283773A5/en not_active IP Right Cessation
- 1989-04-26 RU SU894613974A patent/RU1780510C/en active
- 1989-04-27 HU HU892014A patent/HU205716B/en not_active IP Right Cessation
- 1989-04-27 JP JP1106104A patent/JPH01313430A/en active Pending
- 1989-04-27 PT PT90387A patent/PT90387B/en not_active IP Right Cessation
- 1989-04-27 IL IL9009889A patent/IL90098A/en not_active IP Right Cessation
- 1989-04-27 AU AU33735/89A patent/AU619004B2/en not_active Ceased
- 1989-04-27 PL PL27915389A patent/PL279153A1/en unknown
- 1989-04-27 DK DK204689A patent/DK204689A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0339555A2 (en) | 1989-11-02 |
| AU3373589A (en) | 1989-11-02 |
| BG60542B2 (en) | 1995-08-28 |
| AU619004B2 (en) | 1992-01-16 |
| DK204689A (en) | 1989-10-29 |
| RU1780510C (en) | 1992-12-07 |
| KR900015740A (en) | 1990-11-10 |
| DE58903076D1 (en) | 1993-02-04 |
| BR8901913A (en) | 1989-11-28 |
| ES2043934T3 (en) | 1994-01-01 |
| DD283773A5 (en) | 1990-10-24 |
| ZA893077B (en) | 1989-12-27 |
| DK204689D0 (en) | 1989-04-27 |
| JPH01313430A (en) | 1989-12-18 |
| PT90387A (en) | 1989-11-10 |
| HUT51490A (en) | 1990-05-28 |
| DE3814323A1 (en) | 1989-11-09 |
| PT90387B (en) | 1994-10-31 |
| EP0339555B1 (en) | 1992-12-23 |
| IL90098A (en) | 1995-11-27 |
| EP0339555A3 (en) | 1990-01-31 |
| NZ228898A (en) | 1992-02-25 |
| ATE83661T1 (en) | 1993-01-15 |
| HU205716B (en) | 1992-06-29 |
| PL279153A1 (en) | 1989-12-27 |
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