PH30950A - Salt of (S) -alpha-phenyl-2-pyridineethanamine useful in therapy. - Google Patents

Salt of (S) -alpha-phenyl-2-pyridineethanamine useful in therapy.

Info

Publication number: PH30950A
Authority: PH; Philippines
Prior art keywords: pyridineethanamine; alpha; phenyl; useful; therapy
Prior art date: 1993-04-01

Application number

PH48016A

Other languages

English (en)

Inventor

Robert J Murray

Balestra Michael

Mathisen Donald

Original Assignee

Fisons Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-04-01

Filing date

1994-03-29

Publication date

1997-12-23

1993-04-01 Priority claimed from PCT/GB1993/000689 external-priority patent/WO1993020052A1/fr

1994-03-29 Application filed by Fisons Corp filed Critical Fisons Corp

1997-12-23 Publication of PH30950A publication Critical patent/PH30950A/en

Links

FWUQWDCOOWEXRY-ZDUSSCGKSA-N lanicemine Chemical compound C([C@H](N)C=1C=CC=CC=1)C1=CC=CC=N1 FWUQWDCOOWEXRY-ZDUSSCGKSA-N 0.000 title 1
150000003839 salts Chemical class 0.000 title 1
238000002560 therapeutic procedure Methods 0.000 title 1
KRCGPQRORHRZRC-SXWHKFHYSA-N (2s)-2-hydroxybutanedioic acid;(1s)-1-phenyl-2-pyridin-2-ylethanamine Chemical compound OC(=O)[C@@H](O)CC(O)=O.C([C@H](N)C=1C=CC=CC=1)C1=CC=CC=N1 KRCGPQRORHRZRC-SXWHKFHYSA-N 0.000 abstract 1
230000001773 anti-convulsant effect Effects 0.000 abstract 1
239000001961 anticonvulsive agent Substances 0.000 abstract 1
229960003965 antiepileptics Drugs 0.000 abstract 1
208000015122 neurodegenerative disease Diseases 0.000 abstract 1
239000004090 neuroprotective agent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PH48016A 1993-04-01 1994-03-29 Salt of (S) -alpha-phenyl-2-pyridineethanamine useful in therapy. PH30950A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
PCT/GB1993/000689 WO1993020052A1 (fr)	1992-04-03	1993-04-01	1-phenyl-2-(2-pyridinyl)ethylamine enantiomere pour le traitement de maladies de degenerescence du systeme nerveux
GB939320273A GB9320273D0 (en)	1993-04-01	1993-10-01	Compound useful in therapy

Publications (1)

Publication Number	Publication Date
PH30950A true PH30950A (en)	1997-12-23

Family

ID=26302299

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH48016A PH30950A (en)	1993-04-01	1994-03-29	Salt of (S) -alpha-phenyl-2-pyridineethanamine useful in therapy.

Country Status (19)

Country	Link
EP (1)	EP0691957B1 (fr)
JP (1)	JP3023987B2 (fr)
CN (1)	CN1047168C (fr)
AT (1)	ATE156813T1 (fr)
AU (1)	AU682348B2 (fr)
CA (1)	CA2159478C (fr)
DE (1)	DE69404974T2 (fr)
DK (1)	DK0691957T3 (fr)
DZ (1)	DZ1765A1 (fr)
ES (1)	ES2105672T3 (fr)
FI (1)	FI109018B (fr)
GB (1)	GB9320273D0 (fr)
GR (1)	GR3025081T3 (fr)
IL (1)	IL109108A (fr)
MA (1)	MA23154A1 (fr)
NO (1)	NO304647B1 (fr)
PH (1)	PH30950A (fr)
SG (1)	SG48204A1 (fr)
WO (1)	WO1994022831A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0356035B1 (fr) *	1988-08-12	1996-03-13	Astra Aktiebolag	Arylalkyl-amines et -amides à activité anticonvulsive et neuroprotectrice
ZA942140B (en) *	1993-04-01	1994-10-03	Fisons Corp	Salt of (S)-alpha-phenyl-2-pyridineethanamine useful in therapy
SE9901340D0 (sv) *	1999-04-15	1999-04-15	Astra Pharma Prod	Novel process
SE9901338D0 (sv) *	1999-04-15	1999-04-15	Astra Pharma Prod	Novel process
DE10301650A1 (de) *	2003-01-17	2004-07-29	Johannes-Gutenberg-Universität Mainz	Medizinisch nützliche 1-Phenyl-2-aminomethylnaphthaline, Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung
EP2391606A4 (fr)	2008-12-24	2012-06-13	Astrazeneca Ab	Composés d'éthanamine et leur application pour le traitement de la dépression

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3422191A (en) *	1965-01-21	1969-01-14	Synergistics Inc	Compositions and methods for tranquilization employing salts of n-morpholine ethanol
EP0356035B1 (fr) *	1988-08-12	1996-03-13	Astra Aktiebolag	Arylalkyl-amines et -amides à activité anticonvulsive et neuroprotectrice
JP2514855B2 (ja) *	1990-08-08	1996-07-10	キッセイ薬品工業株式会社	光学活性なアラニンアニリド誘導体の酸付加塩
KR100259567B1 (ko) *	1992-04-03	2000-07-01	클래스 빌헬름슨	신경변성 질환 치료용 1-페닐-2-(2-피리디닐)에틸아민 에난티오머

1993
- 1993-10-01 GB GB939320273A patent/GB9320273D0/en active Pending
1994
- 1994-03-24 IL IL10910894A patent/IL109108A/en not_active IP Right Cessation
- 1994-03-29 DK DK94911232.0T patent/DK0691957T3/da active
- 1994-03-29 WO PCT/GB1994/000651 patent/WO1994022831A1/fr not_active Ceased
- 1994-03-29 ES ES94911232T patent/ES2105672T3/es not_active Expired - Lifetime
- 1994-03-29 EP EP94911232A patent/EP0691957B1/fr not_active Expired - Lifetime
- 1994-03-29 AU AU63802/94A patent/AU682348B2/en not_active Expired
- 1994-03-29 PH PH48016A patent/PH30950A/en unknown
- 1994-03-29 SG SG1996007883A patent/SG48204A1/en unknown
- 1994-03-29 AT AT94911232T patent/ATE156813T1/de active
- 1994-03-29 JP JP6521814A patent/JP3023987B2/ja not_active Expired - Lifetime
- 1994-03-29 CA CA002159478A patent/CA2159478C/fr not_active Expired - Lifetime
- 1994-03-29 DE DE69404974T patent/DE69404974T2/de not_active Expired - Lifetime
- 1994-03-30 DZ DZ940029A patent/DZ1765A1/fr active
- 1994-04-01 CN CN94103739A patent/CN1047168C/zh not_active Expired - Lifetime
- 1994-04-01 MA MA23459A patent/MA23154A1/fr unknown
1995
- 1995-09-28 NO NO951546A patent/NO304647B1/no not_active IP Right Cessation
- 1995-09-29 FI FI954645A patent/FI109018B/fi not_active IP Right Cessation
1997
- 1997-10-17 GR GR970402722T patent/GR3025081T3/el unknown

Also Published As

Publication number	Publication date
IL109108A (en)	1999-01-26
NO953846L (no)	1995-11-21
FI954645A0 (fi)	1995-09-29
EP0691957A1 (fr)	1996-01-17
WO1994022831A1 (fr)	1994-10-13
SG48204A1 (en)	1998-04-17
MA23154A1 (fr)	1994-12-31
JP3023987B2 (ja)	2000-03-21
CA2159478A1 (fr)	1994-10-13
EP0691957B1 (fr)	1997-08-13
NO304647B1 (no)	1999-01-25
AU682348B2 (en)	1997-10-02
DK0691957T3 (da)	1997-10-27
DE69404974T2 (de)	1997-12-18
IL109108A0 (en)	1994-06-24
FI954645L (fi)	1995-11-29
ATE156813T1 (de)	1997-08-15
NO953846D0 (no)	1995-09-28
GR3025081T3 (en)	1998-01-30
CN1047168C (zh)	1999-12-08
DE69404974D1 (de)	1997-09-18
CN1098095A (zh)	1995-02-01
ES2105672T3 (es)	1997-10-16
GB9320273D0 (en)	1993-11-17
FI109018B (fi)	2002-05-15
CA2159478C (fr)	2005-01-25
AU6380294A (en)	1994-10-24
JPH08508292A (ja)	1996-09-03
DZ1765A1 (fr)	2002-02-17

Publication	Publication Date	Title
EP0584340A4 (en)	1994-09-14	Diagnosis and treatment of various neuralgias
ZA935575B (en)	1994-03-01	Therapeutic agent and its use.
AU1438295A (en)	1995-07-03	Method for treatment of papulo-pustules and comedones of the skin
GB9305759D0 (en)	1993-05-05	Hiv therapy method and agents
PH30950A (en)	1997-12-23	Salt of (S) -alpha-phenyl-2-pyridineethanamine useful in therapy.
AU7484596A (en)	1997-05-22	Combination therapy for the treatment of diabetes and obesity
IL107768A0 (en)	1994-02-27	Treatment of agricultural produce
AU5963396A (en)	1996-12-30	Cis-resorcylide, pharmaceutical composition containing it, use thereof in the treatment of thrombosis and related disorders
AU6575894A (en)	1995-01-24	Body massager
ZA942140B (en)	1994-10-03	Salt of (S)-alpha-phenyl-2-pyridineethanamine useful in therapy
GB2275191B (en)	1996-11-27	Use of antifungal compounds in the treatment of skin disorders
AU1192495A (en)	1995-06-19	Use of selegiline and its derivatives for the treatment of psoriasis
AU3053595A (en)	1995-11-09	Therapeutic treatment and preparations
GB2280848B (en)	1997-01-29	Skin treatment apparatus
GB9312780D0 (en)	1993-08-04	Therapeutic and cosmetic treatment
ZA947262B (en)	1995-05-23	Use of transdermal device containing (e)-2-(p-fluorophenethyl)-3-fluoroallylamine and its use for the treatment of alzheimer's disease
ZA937015B (en)	1994-04-18	Treatment and diagnosis of cancer
LTIP581A (en)	1994-12-27	Pharmaceutical and its use for the treatment of states of agitation and nerve dysfunctions
IL106658A0 (en)	1993-12-08	Cancer diagnosis and treatment
PL300153A1 (en)	1995-02-20	Pharmaceutical agent supplementing the demand of human body for magnesium and potassium ions
GB9320912D0 (en)	1993-12-01	Treatment of motion sickness
GB9310611D0 (en)	1993-07-07	Skin treatment
GB9520159D0 (en)	1995-12-06	Benzoioc amide retinoids for use in the treatment of skin diseases and cancer
AUPN355995A0 (en)	1995-07-06	Therapeutic agents and uses therefor
AU6247996A (en)	1997-01-22	Use of substituted pentose or hexose derivates in the treatment of aids and aids related neoplastic disorders