PL1631557T3 - Cykliczne hydroksyloaminy jako związki psychoaktywne - Google Patents
Cykliczne hydroksyloaminy jako związki psychoaktywneInfo
- Publication number
- PL1631557T3 PL1631557T3 PL04735609T PL04735609T PL1631557T3 PL 1631557 T3 PL1631557 T3 PL 1631557T3 PL 04735609 T PL04735609 T PL 04735609T PL 04735609 T PL04735609 T PL 04735609T PL 1631557 T3 PL1631557 T3 PL 1631557T3
- Authority
- PL
- Poland
- Prior art keywords
- represent
- psychoactive compounds
- unsaturated ring
- ring selected
- cyclic hydroxylamine
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 title 1
- 125000004122 cyclic group Chemical group 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- VDFVNEFVBPFDSB-UHFFFAOYSA-N 1,3-dioxane Chemical group C1COCOC1 VDFVNEFVBPFDSB-UHFFFAOYSA-N 0.000 abstract 1
- WNXJIVFYUVYPPR-UHFFFAOYSA-N 1,3-dioxolane Chemical compound C1COCO1 WNXJIVFYUVYPPR-UHFFFAOYSA-N 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/94—Oxygen atom, e.g. piperidine N-oxide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0313628A GB0313628D0 (en) | 2003-06-12 | 2003-06-12 | Psychoactive compounds |
| GB0328439A GB0328439D0 (en) | 2003-12-08 | 2003-12-08 | Psychoactive compounds |
| EP04735609A EP1631557B1 (en) | 2003-06-12 | 2004-06-01 | Cyclic hydroxylamine as psychoactive compounds |
| PCT/GB2004/002324 WO2004111021A1 (en) | 2003-06-12 | 2004-06-01 | Cyclic hydroxylamine as psychoactive compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1631557T3 true PL1631557T3 (pl) | 2007-05-31 |
Family
ID=33554147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL04735609T PL1631557T3 (pl) | 2003-06-12 | 2004-06-01 | Cykliczne hydroksyloaminy jako związki psychoaktywne |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US7842689B2 (pl) |
| EP (1) | EP1631557B1 (pl) |
| JP (1) | JP4648899B2 (pl) |
| KR (1) | KR20060018253A (pl) |
| AT (1) | ATE348818T1 (pl) |
| AU (1) | AU2004247462B2 (pl) |
| BR (1) | BRPI0411124A (pl) |
| CA (1) | CA2526209A1 (pl) |
| DE (1) | DE602004003810T2 (pl) |
| DK (1) | DK1631557T3 (pl) |
| ES (1) | ES2278321T3 (pl) |
| MX (1) | MXPA05013464A (pl) |
| NO (1) | NO20060178L (pl) |
| NZ (1) | NZ544028A (pl) |
| PL (1) | PL1631557T3 (pl) |
| PT (1) | PT1631557E (pl) |
| RU (1) | RU2006101055A (pl) |
| SI (1) | SI1631557T1 (pl) |
| WO (1) | WO2004111021A1 (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20060258A1 (it) | 2006-02-13 | 2007-08-14 | Abiogen Pharma Spa | Procedimento per la preparazione di 2-4 idrossi-3-morfolini-2-cicloesenone |
| UY32858A (es) | 2009-08-31 | 2011-03-31 | Abbott Healthcare Products Bv | Derivados de (tio)morfolina como moduladores de sip |
| EP2345639A1 (en) * | 2009-12-24 | 2011-07-20 | ABIOGEN PHARMA S.p.A. | Cyclic hydroxylamine derivatives, their preparation and use as antioxidants |
| TW201643169A (zh) | 2010-07-09 | 2016-12-16 | 艾伯維股份有限公司 | 作為s1p調節劑的螺-哌啶衍生物 |
| TWI522361B (zh) | 2010-07-09 | 2016-02-21 | 艾伯維公司 | 作為s1p調節劑的稠合雜環衍生物 |
| TW201206893A (en) | 2010-07-09 | 2012-02-16 | Abbott Healthcare Products Bv | Bisaryl (thio) morpholine derivatives as S1P modulators |
| EP2808023A1 (en) * | 2013-05-30 | 2014-12-03 | Université Pierre et Marie Curie (Paris 6) | New drug for the treatment and/or prevention of depressive disorders |
| CN114728982A (zh) | 2019-10-31 | 2022-07-08 | 逃逸生物有限公司 | 固体形式的s1p-受体调节剂 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4241071A (en) * | 1977-01-27 | 1980-12-23 | American Hoechst Corporation | Antidepressant (α-phenyl-2-tolyl)azacycloalkanes |
| DK140584A (da) | 1983-03-08 | 1984-09-09 | Bristol Myers Co | Fremgangsmaade til fremstilling af carbapenemderivater |
| WO1990014342A1 (en) | 1989-05-24 | 1990-11-29 | Pharmacia Ab | Substituted isoxazolidines and isoxazolines |
| GB2264299B (en) * | 1992-02-19 | 1995-07-26 | British Tech Group | Iso-oxazolidine derivatives |
| JP3118061B2 (ja) * | 1992-03-12 | 2000-12-18 | 高砂香料工業株式会社 | 光学活性ヒドロキシルアミンの製造法 |
| GB9226857D0 (en) * | 1992-12-23 | 1993-02-17 | Boyd Edward A | Pharmaceutical compositions |
| IL112099A (en) | 1993-12-23 | 1999-07-14 | Ortho Pharma Corp | N-oxides of 4-arylpiperazines and 4-arylpiperidines and pharmaceutical compositions containing them |
| DE69736390T2 (de) * | 1996-10-07 | 2007-07-26 | Merck Sharp & Dohme Ltd., Hoddesdon | Zns-penetrierende nk-1 rezeptorantagonisten als antidepressivum und / oder anxiolytikum |
| EP0991622A1 (en) * | 1997-06-27 | 2000-04-12 | MERCK SHARP & DOHME LTD. | Substituted 3-(benzylamino)piperidine derivatives and their use as therapeutic agents |
-
2004
- 2004-06-01 PL PL04735609T patent/PL1631557T3/pl unknown
- 2004-06-01 CA CA002526209A patent/CA2526209A1/en not_active Abandoned
- 2004-06-01 BR BRPI0411124-9A patent/BRPI0411124A/pt not_active IP Right Cessation
- 2004-06-01 DK DK04735609T patent/DK1631557T3/da active
- 2004-06-01 JP JP2006516370A patent/JP4648899B2/ja not_active Expired - Fee Related
- 2004-06-01 NZ NZ544028A patent/NZ544028A/en not_active IP Right Cessation
- 2004-06-01 SI SI200430202T patent/SI1631557T1/sl unknown
- 2004-06-01 WO PCT/GB2004/002324 patent/WO2004111021A1/en not_active Ceased
- 2004-06-01 AT AT04735609T patent/ATE348818T1/de active
- 2004-06-01 KR KR1020057023634A patent/KR20060018253A/ko not_active Ceased
- 2004-06-01 EP EP04735609A patent/EP1631557B1/en not_active Expired - Lifetime
- 2004-06-01 AU AU2004247462A patent/AU2004247462B2/en not_active Ceased
- 2004-06-01 DE DE602004003810T patent/DE602004003810T2/de not_active Expired - Lifetime
- 2004-06-01 US US10/559,180 patent/US7842689B2/en not_active Expired - Fee Related
- 2004-06-01 RU RU2006101055/04A patent/RU2006101055A/ru not_active Application Discontinuation
- 2004-06-01 PT PT04735609T patent/PT1631557E/pt unknown
- 2004-06-01 ES ES04735609T patent/ES2278321T3/es not_active Expired - Lifetime
- 2004-06-01 MX MXPA05013464A patent/MXPA05013464A/es active IP Right Grant
-
2006
- 2006-01-11 NO NO20060178A patent/NO20060178L/no not_active Application Discontinuation
-
2009
- 2009-08-18 US US12/461,606 patent/US7842690B2/en not_active Expired - Fee Related
-
2010
- 2010-06-15 US US12/801,568 patent/US8053432B2/en not_active Expired - Fee Related
-
2011
- 2011-08-05 US US13/137,325 patent/US20120015947A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PT1631557E (pt) | 2007-03-30 |
| AU2004247462B2 (en) | 2010-09-02 |
| DE602004003810T2 (de) | 2007-10-11 |
| KR20060018253A (ko) | 2006-02-28 |
| NO20060178L (no) | 2006-01-11 |
| DK1631557T3 (da) | 2007-05-07 |
| NZ544028A (en) | 2009-07-31 |
| BRPI0411124A (pt) | 2006-07-18 |
| US20090312329A1 (en) | 2009-12-17 |
| US8053432B2 (en) | 2011-11-08 |
| CA2526209A1 (en) | 2004-12-23 |
| US7842690B2 (en) | 2010-11-30 |
| US20060142286A1 (en) | 2006-06-29 |
| JP4648899B2 (ja) | 2011-03-09 |
| JP2006527242A (ja) | 2006-11-30 |
| EP1631557A1 (en) | 2006-03-08 |
| WO2004111021A1 (en) | 2004-12-23 |
| US7842689B2 (en) | 2010-11-30 |
| US20100256150A1 (en) | 2010-10-07 |
| AU2004247462A1 (en) | 2004-12-23 |
| US20120015947A1 (en) | 2012-01-19 |
| RU2006101055A (ru) | 2006-07-10 |
| DE602004003810D1 (de) | 2007-02-01 |
| MXPA05013464A (es) | 2006-03-17 |
| HK1087123A1 (en) | 2006-10-06 |
| ATE348818T1 (de) | 2007-01-15 |
| SI1631557T1 (sl) | 2007-06-30 |
| ES2278321T3 (es) | 2007-08-01 |
| EP1631557B1 (en) | 2006-12-20 |
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