PL1638539T3 - Kompozycje farmaceutyczne zawierające czułe na pH kopolimery blokowe i lek hydrofobowy - Google Patents

Kompozycje farmaceutyczne zawierające czułe na pH kopolimery blokowe i lek hydrofobowy

Info

Publication number: PL1638539T3
Authority: PL; Poland
Prior art keywords: pharmaceutical compositions; block copolymers; poly; alkyl; hydrophobic drug
Prior art date: 2003-06-25

Application number

PL04727195T

Other languages

English (en)

Inventor

Vinayak Sant

Jean-Christophe Leroux

Original Assignee

Univ Montreal

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-06-25

Filing date

2004-04-14

Publication date

2009-10-30

2004-04-14 Application filed by Univ Montreal filed Critical Univ Montreal

2009-10-30 Publication of PL1638539T3 publication Critical patent/PL1638539T3/pl

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 3
229920001400 block copolymer Polymers 0.000 title abstract 2
239000003814 drug Substances 0.000 title abstract 2
229940079593 drug Drugs 0.000 title abstract 2
230000002209 hydrophobic effect Effects 0.000 title abstract 2
230000000712 assembly Effects 0.000 abstract 2
238000000429 assembly Methods 0.000 abstract 2
239000000693 micelle Substances 0.000 abstract 2
-1 poly(ethylene oxide) Polymers 0.000 abstract 2
SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 abstract 1
NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
239000013543 active substance Substances 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
150000001768 cations Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000007613 environmental effect Effects 0.000 abstract 1
230000002349 favourable effect Effects 0.000 abstract 1
229920000642 polymer Polymers 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C08L71/02—Polyalkylene oxides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Emergency Medicine (AREA)
Dispersion Chemistry (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Polymers & Plastics (AREA)
Oncology (AREA)
Cardiology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Transplantation (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Cephalosporin Compounds (AREA)

PL04727195T 2003-06-25 2004-04-14 Kompozycje farmaceutyczne zawierające czułe na pH kopolimery blokowe i lek hydrofobowy PL1638539T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US10/607,446 US7094810B2 (en)	2001-06-08	2003-06-25	pH-sensitive block copolymers for pharmaceutical compositions
PCT/CA2004/000561 WO2004112757A1 (en)	2003-06-25	2004-04-14	Pharmaceutical compositions comprising ph-sensitive block copolymers and a hydrophobic drug
EP04727195A EP1638539B1 (en)	2003-06-25	2004-04-14	Pharmaceutical compositions comprising ph-sensitive block copolymers and a hydrophobic drug

Publications (1)

Publication Number	Publication Date
PL1638539T3 true PL1638539T3 (pl)	2009-10-30

Family

ID=33540273

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL04727195T PL1638539T3 (pl)	2003-06-25	2004-04-14	Kompozycje farmaceutyczne zawierające czułe na pH kopolimery blokowe i lek hydrofobowy

Country Status (16)

Country	Link
US (1)	US7094810B2 (pl)
EP (1)	EP1638539B1 (pl)
JP (1)	JP4619357B2 (pl)
AT (1)	ATE418970T1 (pl)
AU (1)	AU2004248863B2 (pl)
BR (1)	BRPI0411872A (pl)
CA (1)	CA2530736C (pl)
CY (1)	CY1110264T1 (pl)
DE (1)	DE602004018772D1 (pl)
DK (1)	DK1638539T3 (pl)
ES (1)	ES2323701T3 (pl)
MX (1)	MXPA05014017A (pl)
PL (1)	PL1638539T3 (pl)
PT (1)	PT1638539E (pl)
SI (1)	SI1638539T1 (pl)
WO (1)	WO2004112757A1 (pl)

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JP2018509387A (ja)	2015-01-21	2018-04-05	フェーズアールエックスインコーポレイテッド	細胞に治療および診断剤を送達するための方法、組成物、ならびにシステム
JP2019513151A (ja)	2016-03-08	2019-05-23	ロスガトスファーマスーティカルズ，インク．ＬｏｓＧａｔｏｓＰｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ．	カンプトテシン誘導体及びその使用
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2003
- 2003-06-25 US US10/607,446 patent/US7094810B2/en not_active Expired - Lifetime
2004
- 2004-04-14 DK DK04727195T patent/DK1638539T3/da active
- 2004-04-14 MX MXPA05014017A patent/MXPA05014017A/es active IP Right Grant
- 2004-04-14 ES ES04727195T patent/ES2323701T3/es not_active Expired - Lifetime
- 2004-04-14 CA CA2530736A patent/CA2530736C/en not_active Expired - Lifetime
- 2004-04-14 JP JP2006515571A patent/JP4619357B2/ja not_active Expired - Lifetime
- 2004-04-14 AT AT04727195T patent/ATE418970T1/de active
- 2004-04-14 WO PCT/CA2004/000561 patent/WO2004112757A1/en not_active Ceased
- 2004-04-14 SI SI200431088T patent/SI1638539T1/sl unknown
- 2004-04-14 AU AU2004248863A patent/AU2004248863B2/en not_active Ceased
- 2004-04-14 PT PT04727195T patent/PT1638539E/pt unknown
- 2004-04-14 EP EP04727195A patent/EP1638539B1/en not_active Expired - Lifetime
- 2004-04-14 BR BRPI0411872-3A patent/BRPI0411872A/pt not_active IP Right Cessation
- 2004-04-14 PL PL04727195T patent/PL1638539T3/pl unknown
- 2004-04-14 DE DE602004018772T patent/DE602004018772D1/de not_active Expired - Lifetime
2009
- 2009-03-31 CY CY20091100371T patent/CY1110264T1/el unknown

Also Published As

Publication number	Publication date
US20040072784A1 (en)	2004-04-15
DK1638539T3 (da)	2009-05-04
ATE418970T1 (de)	2009-01-15
ES2323701T3 (es)	2009-07-23
AU2004248863A1 (en)	2004-12-29
WO2004112757A1 (en)	2004-12-29
US7094810B2 (en)	2006-08-22
JP2007505029A (ja)	2007-03-08
PT1638539E (pt)	2009-04-09
BRPI0411872A (pt)	2006-08-08
CY1110264T1 (el)	2015-01-14
EP1638539A1 (en)	2006-03-29
AU2004248863B2 (en)	2009-03-12
MXPA05014017A (es)	2007-01-31
DE602004018772D1 (de)	2009-02-12
CA2530736C (en)	2013-07-02
CA2530736A1 (en)	2004-12-29
JP4619357B2 (ja)	2011-01-26
EP1638539B1 (en)	2008-12-31
SI1638539T1 (sl)	2009-10-31

Publication	Publication Date	Title
SI1638539T1 (sl)	2009-10-31	FARMACEVTSKI SESTAVKI, KI VSEBUJEJO pH OBÄŚUTLJIVE BLOK KOPOLIMERE IN HIDROFOBNO ZDRAVILNO UÄŚINKOVINO
WO2003044076A8 (en)	2004-07-29	Bioerodible poly(ortho esters) containing amine groups, and block copolymers containing them
CA2462606A1 (en)	2003-04-17	Orally administered liquid compositions comprising guaifenesin and a polyoxyalkylene block copolymer
DE60044459D1 (de)	2010-07-08	IN ORGANISCHEN LÖSEMITTELN LÖSLICHE BIOLOGISCH ABBAUBARE POLY (ALKYLENOXID)- POLY (p-DIOXANON) BLOCKCOPOLYMERE SOWIE DIESE ENTHALTENDE ZUSAMMENSETZUNG ZUR ARZNEISTOFFVERABREICHUNG
ATE313586T1 (de)	2006-01-15	Mehrarmige blockcopolymere und pharmazeutische zusammensetzung
CA2430481A1 (en)	2002-06-13	Compositions for sustained delivery of hydrophobic drugs and process for the preparation thereof
CA2483282A1 (en)	2003-11-13	Polymeric microemulsions
CA2408716A1 (en)	2001-11-22	Stable polymeric micelle-type drug composition and method for the preparation thereof
BR0111016A (pt)	2003-04-15	Composições farmacêuticas de liberação sustentada para a administração parenteral de compostos hidrófilos biologicamente ativos
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