PL1638539T3 - Kompozycje farmaceutyczne zawierające czułe na pH kopolimery blokowe i lek hydrofobowy - Google Patents

Kompozycje farmaceutyczne zawierające czułe na pH kopolimery blokowe i lek hydrofobowy

Info

Publication number
PL1638539T3
PL1638539T3 PL04727195T PL04727195T PL1638539T3 PL 1638539 T3 PL1638539 T3 PL 1638539T3 PL 04727195 T PL04727195 T PL 04727195T PL 04727195 T PL04727195 T PL 04727195T PL 1638539 T3 PL1638539 T3 PL 1638539T3
Authority
PL
Poland
Prior art keywords
pharmaceutical compositions
compositions containing
block copolymers
hydrophobic drug
poly
Prior art date
Application number
PL04727195T
Other languages
English (en)
Inventor
Vinayak Sant
Jean-Christophe Leroux
Original Assignee
Univ Montreal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Montreal filed Critical Univ Montreal
Publication of PL1638539T3 publication Critical patent/PL1638539T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Polymers & Plastics (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
PL04727195T 2003-06-25 2004-04-14 Kompozycje farmaceutyczne zawierające czułe na pH kopolimery blokowe i lek hydrofobowy PL1638539T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/607,446 US7094810B2 (en) 2001-06-08 2003-06-25 pH-sensitive block copolymers for pharmaceutical compositions
PCT/CA2004/000561 WO2004112757A1 (en) 2003-06-25 2004-04-14 Pharmaceutical compositions comprising ph-sensitive block copolymers and a hydrophobic drug
EP04727195A EP1638539B1 (en) 2003-06-25 2004-04-14 Pharmaceutical compositions comprising ph-sensitive block copolymers and a hydrophobic drug

Publications (1)

Publication Number Publication Date
PL1638539T3 true PL1638539T3 (pl) 2009-10-30

Family

ID=33540273

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04727195T PL1638539T3 (pl) 2003-06-25 2004-04-14 Kompozycje farmaceutyczne zawierające czułe na pH kopolimery blokowe i lek hydrofobowy

Country Status (16)

Country Link
US (1) US7094810B2 (pl)
EP (1) EP1638539B1 (pl)
JP (1) JP4619357B2 (pl)
AT (1) ATE418970T1 (pl)
AU (1) AU2004248863B2 (pl)
BR (1) BRPI0411872A (pl)
CA (1) CA2530736C (pl)
CY (1) CY1110264T1 (pl)
DE (1) DE602004018772D1 (pl)
DK (1) DK1638539T3 (pl)
ES (1) ES2323701T3 (pl)
MX (1) MXPA05014017A (pl)
PL (1) PL1638539T3 (pl)
PT (1) PT1638539E (pl)
SI (1) SI1638539T1 (pl)
WO (1) WO2004112757A1 (pl)

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JP2010504318A (ja) * 2006-09-22 2010-02-12 ラボファーム インコーポレイテッド ｐＨ標的化薬剤送達のための組成物及び方法
EP2097140B1 (en) * 2006-12-20 2012-09-26 Arkema Inc. Polymer encapsulation and/or binding
EP2150235A4 (en) * 2007-04-20 2013-07-03 Univ South Australia Capsule formulation coated with nanoparticles for the purpose of dermal drug administration
KR20100065190A (ko) * 2007-09-14 2010-06-15 닛토덴코 가부시키가이샤 약물 담체
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US8778400B2 (en) * 2008-04-21 2014-07-15 University Of South Australia Nanoparticle-stabilized capsule formulation for treatment of inflammation
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WO2009140423A2 (en) * 2008-05-13 2009-11-19 University Of Washington Targeted polymer bioconjugates
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JP2012507581A (ja) 2008-11-06 2012-03-29 ユニヴァーシティ オブ ワシントン 二重特異性細胞内送達媒体
WO2010077678A2 (en) 2008-12-08 2010-07-08 University Of Washington Omega-functionalized polymers, junction-functionalized block copolymers, polymer bioconjugates, and radical chain extension polymerization
US20100159010A1 (en) * 2008-12-24 2010-06-24 Mutual Pharmaceutical Company, Inc. Active Agent Formulations, Methods of Making, and Methods of Use
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WO2011062965A2 (en) 2009-11-18 2011-05-26 University Of Washington Through Its Center For Commercialization Targeting monomers and polymers having targeting blocks
AU2014296278C1 (en) 2013-07-30 2023-02-02 Genevant Sciences Gmbh Block copolymers and their conjugates or complexes with oligonucleotides
CN114642735A (zh) 2015-01-21 2022-06-21 菲泽尔克斯公司 用于将治疗剂和诊断剂递送到细胞中的方法、组合物和系统
US10064855B2 (en) 2016-03-08 2018-09-04 Los Gatos Pharmaceuticals, Inc. Composite nanoparticles and uses thereof
WO2017156183A1 (en) 2016-03-08 2017-09-14 Los Gatos Pharmaceuticals, Inc. Camptothecin derivatives and uses thereof
CN106432647B (zh) * 2016-09-26 2018-10-30 华南理工大学 基于叔氨基的pH响应嵌段聚合物及其混合胶束与应用
US11684584B2 (en) 2016-12-30 2023-06-27 Genevant Sciences Gmbh Branched peg molecules and related compositions and methods
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Also Published As

Publication number Publication date
JP4619357B2 (ja) 2011-01-26
CY1110264T1 (el) 2015-01-14
MXPA05014017A (es) 2007-01-31
JP2007505029A (ja) 2007-03-08
ATE418970T1 (de) 2009-01-15
WO2004112757A1 (en) 2004-12-29
CA2530736C (en) 2013-07-02
CA2530736A1 (en) 2004-12-29
SI1638539T1 (sl) 2009-10-31
DE602004018772D1 (de) 2009-02-12
AU2004248863A1 (en) 2004-12-29
BRPI0411872A (pt) 2006-08-08
PT1638539E (pt) 2009-04-09
EP1638539A1 (en) 2006-03-29
US20040072784A1 (en) 2004-04-15
DK1638539T3 (da) 2009-05-04
ES2323701T3 (es) 2009-07-23
AU2004248863B2 (en) 2009-03-12
US7094810B2 (en) 2006-08-22
EP1638539B1 (en) 2008-12-31

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