PL1670769T3 - Pochodne benzimidazolu, kompozycje zawierające te związki, ich wytwarzanie i zastosowanie - Google Patents

Pochodne benzimidazolu, kompozycje zawierające te związki, ich wytwarzanie i zastosowanie

Info

Publication number: PL1670769T3
Authority: PL; Poland
Prior art keywords: preparation; compositions containing; benzimidazole derivatives; benzimidazole; derivatives
Prior art date: 2003-09-26

Application number

PL04768667T

Other languages

English (en)

Inventor

Ziping Liu

Daniel Page

Christopher Walpole

Hua Yang

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-09-26

Filing date

2004-09-24

Publication date

2009-09-30

2004-09-24 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2009-09-30 Publication of PL1670769T3 publication Critical patent/PL1670769T3/pl

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/14—Radicals substituted by nitrogen atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

PL04768667T 2003-09-26 2004-09-24 Pochodne benzimidazolu, kompozycje zawierające te związki, ich wytwarzanie i zastosowanie PL1670769T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
SE0302573A SE0302573D0 (sv)	2003-09-26	2003-09-26	Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
EP04768667A EP1670769B1 (en)	2003-09-26	2004-09-24	Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
PCT/GB2004/004124 WO2005030732A1 (en)	2003-09-26	2004-09-24	Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof

Publications (1)

Publication Number	Publication Date
PL1670769T3 true PL1670769T3 (pl)	2009-09-30

Family

ID=29246982

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL04768667T PL1670769T3 (pl)	2003-09-26	2004-09-24	Pochodne benzimidazolu, kompozycje zawierające te związki, ich wytwarzanie i zastosowanie

Country Status (33)

Country	Link
US (1)	US8633235B2 (pl)
EP (1)	EP1670769B1 (pl)
JP (1)	JP4896721B2 (pl)
KR (1)	KR101170184B1 (pl)
CN (2)	CN1886379A (pl)
AR (1)	AR045819A1 (pl)
AT (1)	ATE430135T1 (pl)
AU (1)	AU2004276062B2 (pl)
BR (1)	BRPI0414780B8 (pl)
CA (1)	CA2539738C (pl)
CO (1)	CO5680443A2 (pl)
CY (1)	CY1110332T1 (pl)
DE (1)	DE602004020907D1 (pl)
DK (1)	DK1670769T3 (pl)
ES (1)	ES2324669T3 (pl)
HR (1)	HRP20090388T1 (pl)
IL (1)	IL174215A0 (pl)
IS (1)	IS8422A (pl)
MX (1)	MXPA06003197A (pl)
MY (1)	MY140630A (pl)
NO (1)	NO20061839L (pl)
NZ (1)	NZ545736A (pl)
PL (1)	PL1670769T3 (pl)
PT (1)	PT1670769E (pl)
RU (1)	RU2346938C2 (pl)
SA (1)	SA04250310B1 (pl)
SE (1)	SE0302573D0 (pl)
SI (1)	SI1670769T1 (pl)
TW (1)	TW200521117A (pl)
UA (1)	UA86776C2 (pl)
UY (1)	UY28536A1 (pl)
WO (1)	WO2005030732A1 (pl)
ZA (3)	ZA200602446B (pl)

Families Citing this family (22)

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US7091216B2 (en)	2002-08-02	2006-08-15	Merck & Co., Inc.	Substituted furo[2,3-b]pyridine derivatives
SE0302573D0 (sv)	2003-09-26	2003-09-26	Astrazeneca Ab	Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
UA87327C2 (ru) *	2004-09-24	2009-07-10	Астразенека Аб	Производные бензимидазола, композиция, которая их содержит, их получение и применение
WO2006033630A1 (en) *	2004-09-24	2006-03-30	Astrazeneca Ab	Compounds, compositions containing them, preparation thereof and uses thereof iii
WO2006033631A1 (en) *	2004-09-24	2006-03-30	Astrazeneca Ab	Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof i
MX2007003105A (es)	2004-09-24	2007-06-07	Aztrazeneca Ab	Derivados de bencimidazol, composiciones que los contienen, sus preparaciones y sus usos i.
EP1809607B1 (en)	2004-11-02	2008-12-17	Pfizer, Inc.	Sulfonyl benzimidazole derivatives
JP2009502912A (ja) *	2005-07-29	2009-01-29	アストラゼネカ・アクチエボラーグ	ジェミナル（（ジフルオロシクロアルキル）メチル）アミンの製造方法
TW200745049A (en) *	2006-03-23	2007-12-16	Astrazeneca Ab	New crystalline forms
TW200808769A (en) *	2006-04-18	2008-02-16	Astrazeneca Ab	Therapeutic compounds
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JP5159630B2 (ja) *	2006-09-13	2013-03-06	協和発酵キリン株式会社	縮環複素環誘導体
US20110086853A1 (en) *	2009-10-08	2011-04-14	William Brown	Therapeutic Compounds
RU2414899C1 (ru) *	2009-12-29	2011-03-27	Аверин Константин Михайлович	Средства для лечения рассеянного склероза
RU2454234C1 (ru) *	2011-03-16	2012-06-27	Константин Михайлович Аверин	Соли 1,3-диэтилбензимидазолия - иммуностимулирующие средства и фармацевтические композиции на их основе
JP2015529692A (ja) *	2012-06-13	2015-10-08	サイテク・テクノロジー・コーポレーシヨン	置換クロマン化合物を含む安定剤組成物および使用方法
BR112014032538A2 (pt)	2012-06-26	2017-06-27	Bayer Pharma AG	n-[4-(quinolin-4-ilóxi)ciclo-hexil(metil)] (hetero)arilcarboxamidas como antagonistas do receptor de andrógeno, produção e uso das mesmas como produtos medicinais
WO2019170543A1 (en)	2018-03-07	2019-09-12	Bayer Aktiengesellschaft	Identification and use of erk5 inhibitors
US20220227729A1 (en)	2019-05-21	2022-07-21	Bayer Aktiengesellschaft	Identification and use of kras inhibitors
CN112010789A (zh) *	2019-05-31	2020-12-01	中国科学院上海药物研究所	乙烯基磺酰胺或乙烯基酰胺类化合物及其制备方法和用途
GB202019335D0 (en) *	2020-12-08	2021-01-20	Artelo Biosciences Ltd	Pharmaceutical compositions
US20250171451A1 (en) *	2022-03-04	2025-05-29	Samjin Pharmaceutical Co., Ltd.	Novel heterocyclic compound and pharmaceutical composition comprising same

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2003
- 2003-09-26 SE SE0302573A patent/SE0302573D0/xx unknown
2004
- 2004-09-24 US US10/573,054 patent/US8633235B2/en active Active
- 2004-09-24 CA CA2539738A patent/CA2539738C/en not_active Expired - Lifetime
- 2004-09-24 UY UY28536A patent/UY28536A1/es unknown
- 2004-09-24 CN CNA2004800350086A patent/CN1886379A/zh active Pending
- 2004-09-24 WO PCT/GB2004/004124 patent/WO2005030732A1/en not_active Ceased
- 2004-09-24 SI SI200431166T patent/SI1670769T1/sl unknown
- 2004-09-24 JP JP2006527490A patent/JP4896721B2/ja not_active Expired - Lifetime
- 2004-09-24 EP EP04768667A patent/EP1670769B1/en not_active Expired - Lifetime
- 2004-09-24 BR BRPI0414780A patent/BRPI0414780B8/pt not_active IP Right Cessation
- 2004-09-24 PL PL04768667T patent/PL1670769T3/pl unknown
- 2004-09-24 AT AT04768667T patent/ATE430135T1/de active
- 2004-09-24 NZ NZ545736A patent/NZ545736A/en unknown
- 2004-09-24 ES ES04768667T patent/ES2324669T3/es not_active Expired - Lifetime
- 2004-09-24 MY MYPI20043910A patent/MY140630A/en unknown
- 2004-09-24 UA UAA200602693A patent/UA86776C2/ru unknown
- 2004-09-24 KR KR1020067005825A patent/KR101170184B1/ko not_active Expired - Lifetime
- 2004-09-24 AR ARP040103467A patent/AR045819A1/es not_active Application Discontinuation
- 2004-09-24 MX MXPA06003197A patent/MXPA06003197A/es active IP Right Grant
- 2004-09-24 PT PT04768667T patent/PT1670769E/pt unknown
- 2004-09-24 RU RU2006113371/04A patent/RU2346938C2/ru active
- 2004-09-24 CN CN2010105277900A patent/CN102010373A/zh active Pending
- 2004-09-24 DE DE602004020907T patent/DE602004020907D1/de not_active Expired - Lifetime
- 2004-09-24 DK DK04768667T patent/DK1670769T3/da active
- 2004-09-24 AU AU2004276062A patent/AU2004276062B2/en not_active Expired
- 2004-09-24 TW TW093129150A patent/TW200521117A/zh unknown
- 2004-09-24 HR HR20090388T patent/HRP20090388T1/xx unknown
- 2004-09-26 SA SA04250310A patent/SA04250310B1/ar unknown
2006
- 2006-03-09 IL IL174215A patent/IL174215A0/en unknown
- 2006-03-22 CO CO06028452A patent/CO5680443A2/es not_active Application Discontinuation
- 2006-03-24 ZA ZA200602446A patent/ZA200602446B/en unknown
- 2006-04-21 IS IS8422A patent/IS8422A/is unknown
- 2006-04-26 NO NO20061839A patent/NO20061839L/no not_active Application Discontinuation
2007
- 2007-03-13 ZA ZA200702131A patent/ZA200702131B/xx unknown
- 2007-03-16 ZA ZA200702226A patent/ZA200702226B/xx unknown
2009
- 2009-07-08 CY CY20091100725T patent/CY1110332T1/el unknown

Also Published As

Publication number	Publication date
EP1670769A1 (en)	2006-06-21
CA2539738C (en)	2011-11-22
WO2005030732A1 (en)	2005-04-07
RU2346938C2 (ru)	2009-02-20
UY28536A1 (es)	2005-04-29
NZ545736A (en)	2009-11-27
DK1670769T3 (da)	2009-08-10
SI1670769T1 (sl)	2009-10-31
HK1089436A1 (en)	2006-12-01
US20080207612A1 (en)	2008-08-28
BRPI0414780B1 (pt)	2018-10-23
ZA200602446B (en)	2007-09-26
BRPI0414780A (pt)	2006-11-21
CO5680443A2 (es)	2006-09-29
PT1670769E (pt)	2009-07-09
EP1670769B1 (en)	2009-04-29
AR045819A1 (es)	2005-11-16
SA04250310B1 (ar)	2009-01-19
BRPI0414780B8 (pt)	2021-05-25
NO20061839L (no)	2006-06-26
ZA200702131B (en)	2008-08-27
UA86776C2 (ru)	2009-05-25
CN102010373A (zh)	2011-04-13
CA2539738A1 (en)	2005-04-07
TW200521117A (en)	2005-07-01
HRP20090388T1 (hr)	2009-08-31
IL174215A0 (en)	2006-08-01
RU2006113371A (ru)	2007-11-10
KR20070001052A (ko)	2007-01-03
CY1110332T1 (el)	2015-01-14
ES2324669T3 (es)	2009-08-12
KR101170184B1 (ko)	2012-07-31
CN1886379A (zh)	2006-12-27
AU2004276062A1 (en)	2005-04-07
US8633235B2 (en)	2014-01-21
ZA200702226B (en)	2009-01-28
MXPA06003197A (es)	2006-06-23
JP4896721B2 (ja)	2012-03-14
DE602004020907D1 (de)	2009-06-10
SE0302573D0 (sv)	2003-09-26
MY140630A (en)	2010-01-15
AU2004276062B2 (en)	2008-05-22
ATE430135T1 (de)	2009-05-15
JP2007506721A (ja)	2007-03-22
IS8422A (is)	2006-04-21

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