PL1670809T3 - Synteza i wytwarzanie pentostatyny, jej prekursorów analogów i pochodnych - Google Patents

Synteza i wytwarzanie pentostatyny, jej prekursorów analogów i pochodnych

Info

Publication number: PL1670809T3
Authority: PL; Poland
Prior art keywords: pentostatin; analogs; precursors; synthesis; derivatives
Prior art date: 2003-09-15

Application number

PL04784157.2T

Other languages

English (en)

Inventor

Pasit Phiasivongsa

Sanjeev Redkar

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-09-15

Filing date

2004-09-15

Publication date

2016-11-30

2004-09-15 Application filed filed Critical

2016-11-30 Publication of PL1670809T3 publication Critical patent/PL1670809T3/pl

Links

FPVKHBSQESCIEP-UHFFFAOYSA-N (8S)-3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol Natural products C1C(O)C(CO)OC1N1C(NC=NCC2O)=C2N=C1 FPVKHBSQESCIEP-UHFFFAOYSA-N 0.000 title 1
230000015572 biosynthetic process Effects 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
FPVKHBSQESCIEP-JQCXWYLXSA-N pentostatin Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(N=CNC[C@H]2O)=C2N=C1 FPVKHBSQESCIEP-JQCXWYLXSA-N 0.000 title 1
229960002340 pentostatin Drugs 0.000 title 1
239000002243 precursor Substances 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/22—Pteridine radicals

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Saccharide Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PL04784157.2T 2003-09-15 2004-09-15 Synteza i wytwarzanie pentostatyny, jej prekursorów analogów i pochodnych PL1670809T3 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US50323703P	2003-09-15	2003-09-15

Publications (1)

Publication Number	Publication Date
PL1670809T3 true PL1670809T3 (pl)	2016-11-30

Family

ID=34375325

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL04784157.2T PL1670809T3 (pl)	2003-09-15	2004-09-15	Synteza i wytwarzanie pentostatyny, jej prekursorów analogów i pochodnych

Country Status (11)

Country	Link
US (1)	US20050267056A1 (pl)
EP (1)	EP1670809B1 (pl)
JP (1)	JP4830128B2 (pl)
CN (2)	CN101343302B (pl)
CA (1)	CA2538857C (pl)
DK (1)	DK1670809T3 (pl)
ES (1)	ES2567152T3 (pl)
HU (1)	HUE027338T2 (pl)
PL (1)	PL1670809T3 (pl)
SI (1)	SI1670809T1 (pl)
WO (1)	WO2005027838A2 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101798330A (zh) *	2009-02-06	2010-08-11	杭州华东医药集团生物工程研究所有限公司	一种喷司他丁的提取纯化方法
EP3115461A1 (en) *	2015-07-07	2017-01-11	Synbias Pharma AG	Method for the synthesis of pentostatin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS52958B2 (pl) *	1973-11-14	1977-01-11
US4014769A (en) *	1973-11-14	1977-03-29	Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai	Production of coformycin and intermediates therefor
US4195176A (en) *	1977-10-11	1980-03-25	Warner-Lambert Company	Imidazole compounds, methods for their production and conversion of said compounds into (R)-3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazol[4,5-d][1,3]diazepin-8-ol
US4117229A (en) *	1977-10-11	1978-09-26	Warner-Lambert Company	2-amino-1-(5-amino-1h-imidazol-4-yl)ethanone and method of preparation
US4935505A (en) *	1983-05-03	1990-06-19	Townsend Leroy B	Novel azolo [1,3] diazepine-5-ol compounds and their uses
US5773607A (en) *	1991-11-14	1998-06-30	Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai	Processes for preparing 2'-deoxy-2'-fluorocoformycin and stereoisomers thereof
US5843912A (en) *	1994-07-06	1998-12-01	Universy Of Maryland	Ring-expanded nucleosides and nucleotides
US6677310B1 (en) *	1999-04-21	2004-01-13	Nabi	Ring-expanded nucleosides and nucleotides
JPH09241294A (ja) *	1996-03-07	1997-09-16	Microbial Chem Res Found	２′−デオキシ−２′−ハロコホルマイシン又はその立体異性体の製造法

2004
- 2004-09-15 EP EP04784157.2A patent/EP1670809B1/en not_active Expired - Lifetime
- 2004-09-15 US US10/942,319 patent/US20050267056A1/en not_active Abandoned
- 2004-09-15 CN CN2008101336207A patent/CN101343302B/zh not_active Expired - Fee Related
- 2004-09-15 PL PL04784157.2T patent/PL1670809T3/pl unknown
- 2004-09-15 JP JP2006526997A patent/JP4830128B2/ja not_active Expired - Fee Related
- 2004-09-15 DK DK04784157.2T patent/DK1670809T3/en active
- 2004-09-15 CN CNB2004800265986A patent/CN100430410C/zh not_active Expired - Fee Related
- 2004-09-15 SI SI200432316A patent/SI1670809T1/sl unknown
- 2004-09-15 CA CA2538857A patent/CA2538857C/en not_active Expired - Fee Related
- 2004-09-15 HU HUE04784157A patent/HUE027338T2/en unknown
- 2004-09-15 WO PCT/US2004/030203 patent/WO2005027838A2/en not_active Ceased
- 2004-09-15 ES ES04784157.2T patent/ES2567152T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CN101343302B (zh)	2012-07-04
EP1670809A2 (en)	2006-06-21
US20050267056A1 (en)	2005-12-01
CA2538857A1 (en)	2005-03-31
EP1670809B1 (en)	2016-01-13
WO2005027838A3 (en)	2005-06-30
HK1096688A1 (zh)	2007-06-08
EP1670809A4 (en)	2009-12-23
HUE027338T2 (en)	2016-09-28
CN100430410C (zh)	2008-11-05
WO2005027838A2 (en)	2005-03-31
CN1852913A (zh)	2006-10-25
DK1670809T3 (en)	2016-04-18
CA2538857C (en)	2013-06-11
JP2007505909A (ja)	2007-03-15
JP4830128B2 (ja)	2011-12-07
SI1670809T1 (sl)	2016-06-30
HK1128192A1 (en)	2009-10-16
CN101343302A (zh)	2009-01-14
ES2567152T3 (es)	2016-04-20

Publication	Publication Date	Title
GB0321607D0 (en)	2003-10-15	Manufacture of pharmaceutical compositions
GB0311774D0 (en)	2003-06-25	Production of olefins
IL173930A0 (en)	2006-07-05	Pharmaceutical compositions containing forms of r-baclofen
MXPA03006403A (es)	2003-10-15	Sintesis de la temozolomida y analogos.
IL176932A0 (en)	2006-12-10	Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof
ZA200407609B (en)	2005-11-30	Use of vitamin d compounds
GB0305150D0 (en)	2003-04-09	Use of therapeutic compounds
AU2003292263A1 (en)	2004-08-10	Use of substituted 2-phenylbenzimidazoles as medicaments
MXPA03006402A (es)	2003-10-15	Sintesis de temozolomida y analogos.
IL166337A0 (en)	2006-01-16	Oral administration of calctionin
IL176131A0 (en)	2006-10-05	Practical, cost-effective synthesis of ubiquinones
GB0204140D0 (en)	2002-04-10	Production of olefins
ITMI20020933A0 (it)	2002-05-03	Procedimento per la sintesi di clopidogrel
ITMI20020991A0 (it)	2002-05-10	Procedimento per la sintesi del modafinil
AU2003246963A8 (en)	2004-02-23	Synthesis of cyclohexanone derivatives
EP1670809A4 (en)	2009-12-23	SYNTHESIS AND PRODUCTION OF PENTOSTATIN, PRECURSORS, ANALOGS AND DERIVATIVES THEREOF
AU2003270202A8 (en)	2004-04-08	Pharmaceutical compositions useful for the treatment of cancers
GB0327742D0 (en)	2003-12-31	Novel uses of known drugs
AU2003298725A8 (en)	2004-06-23	Preparation of metallotexaphyrins
AU2003240174A8 (en)	2003-12-22	Compositions for the treatment of edematous-firbrosclerotic panniculopathy
PL375437A1 (pl)	2005-11-28	Synteza gatifloksacyny
AU2003217354A8 (en)	2003-09-02	Synthesis of sulfamidates
EG24122A (en)	2008-07-06	Process for the synthesis of 3-cyano-6-alkoxy-7-nitro-4-quinolines
HUP0203929D0 (en)	2003-01-28	New use of substituted alkyl-piridazinone derivatives
GB2387171B (en)	2005-05-18	Synthesis of enamines