PL1680140T3 - Inhibitory receptora-1 czynnika wzrostu fibroblastów i związane z nim sposoby leczenia - Google Patents

Inhibitory receptora-1 czynnika wzrostu fibroblastów i związane z nim sposoby leczenia

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Publication number
PL1680140T3
PL1680140T3 PL04796034T PL04796034T PL1680140T3 PL 1680140 T3 PL1680140 T3 PL 1680140T3 PL 04796034 T PL04796034 T PL 04796034T PL 04796034 T PL04796034 T PL 04796034T PL 1680140 T3 PL1680140 T3 PL 1680140T3
Authority
PL
Poland
Prior art keywords
fgfr
methods
treatment
growth factor
factor receptor
Prior art date
Application number
PL04796034T
Other languages
English (en)
Inventor
Haijun Sun
Juqun Shen
James R Tonra
Original Assignee
Imclone Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imclone Llc filed Critical Imclone Llc
Publication of PL1680140T3 publication Critical patent/PL1680140T3/pl

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    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P9/00Drugs for disorders of the cardiovascular system
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    • AHUMAN NECESSITIES
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    • A61P9/00Drugs for disorders of the cardiovascular system
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    • AHUMAN NECESSITIES
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/55Fab or Fab'
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pregnancy & Childbirth (AREA)
PL04796034T 2003-10-16 2004-10-18 Inhibitory receptora-1 czynnika wzrostu fibroblastów i związane z nim sposoby leczenia PL1680140T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US51225503P 2003-10-16 2003-10-16
EP04796034A EP1680140B1 (en) 2003-10-16 2004-10-18 Fibroblast growth factor receptor-1 inhibitors and methods of treatment thereof
PCT/US2004/034970 WO2005037235A2 (en) 2003-10-16 2004-10-18 Fibroblast growth factor receptor-1 inhibitors and methods of treatment thereof

Publications (1)

Publication Number Publication Date
PL1680140T3 true PL1680140T3 (pl) 2011-11-30

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PL04796034T PL1680140T3 (pl) 2003-10-16 2004-10-18 Inhibitory receptora-1 czynnika wzrostu fibroblastów i związane z nim sposoby leczenia

Country Status (13)

Country Link
US (2) US20070274981A1 (pl)
EP (3) EP2229955A1 (pl)
JP (1) JP4686465B2 (pl)
AT (1) ATE506077T1 (pl)
CA (2) CA2542638A1 (pl)
CY (1) CY1111479T1 (pl)
DE (1) DE602004032370D1 (pl)
DK (1) DK1680140T3 (pl)
ES (1) ES2361917T3 (pl)
PL (1) PL1680140T3 (pl)
PT (1) PT1680140E (pl)
SI (1) SI1680140T1 (pl)
WO (1) WO2005037235A2 (pl)

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EP1680140A2 (en) 2006-07-19
EP2060270A3 (en) 2009-12-09
DK1680140T3 (da) 2011-06-14
JP2008501302A (ja) 2008-01-24
EP1680140B1 (en) 2011-04-20
CY1111479T1 (el) 2015-08-05
ES2361917T3 (es) 2011-06-24
EP1680140A4 (en) 2007-12-05
SI1680140T1 (sl) 2011-08-31
CA2762955A1 (en) 2005-04-28
PT1680140E (pt) 2011-05-31
JP4686465B2 (ja) 2011-05-25
WO2005037235A2 (en) 2005-04-28
DE602004032370D1 (de) 2011-06-01
WO2005037235A3 (en) 2005-12-22
EP2229955A1 (en) 2010-09-22
US8263074B2 (en) 2012-09-11
US20120121609A1 (en) 2012-05-17
ATE506077T1 (de) 2011-05-15
EP2060270A2 (en) 2009-05-20
US20070274981A1 (en) 2007-11-29
CA2542638A1 (en) 2005-04-28

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