PL1718338T3 - Kompozycje oraz sposoby do celowanego dostarczania leku in vitro oraz in vivo do ssaczych komórek poprzez bakteriopochodne nienaruszone minikomórki - Google Patents
Kompozycje oraz sposoby do celowanego dostarczania leku in vitro oraz in vivo do ssaczych komórek poprzez bakteriopochodne nienaruszone minikomórkiInfo
- Publication number
- PL1718338T3 PL1718338T3 PL05702361T PL05702361T PL1718338T3 PL 1718338 T3 PL1718338 T3 PL 1718338T3 PL 05702361 T PL05702361 T PL 05702361T PL 05702361 T PL05702361 T PL 05702361T PL 1718338 T3 PL1718338 T3 PL 1718338T3
- Authority
- PL
- Poland
- Prior art keywords
- vitro
- targeted
- compositions
- methods
- drug delivery
- Prior art date
Links
- 238000012377 drug delivery Methods 0.000 title 1
- 238000000338 in vitro Methods 0.000 title 1
- 238000001727 in vivo Methods 0.000 title 1
- 210000004962 mammalian cell Anatomy 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
- A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6875—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody being a hybrid immunoglobulin
- A61K47/6879—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody being a hybrid immunoglobulin the immunoglobulin having two or more different antigen-binding sites, e.g. bispecific or multispecific immunoglobulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Botany (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54059004P | 2004-02-02 | 2004-02-02 | |
| EP20050702361 EP1718338B1 (en) | 2004-02-02 | 2005-01-27 | Compositions and methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells |
| PCT/IB2005/000204 WO2005079854A1 (en) | 2004-02-02 | 2005-01-27 | Compositions and methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1718338T3 true PL1718338T3 (pl) | 2015-12-31 |
Family
ID=34885947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05702361T PL1718338T3 (pl) | 2004-02-02 | 2005-01-27 | Kompozycje oraz sposoby do celowanego dostarczania leku in vitro oraz in vivo do ssaczych komórek poprzez bakteriopochodne nienaruszone minikomórki |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US9867785B2 (pl) |
| EP (2) | EP1718338B1 (pl) |
| JP (2) | JP5060787B2 (pl) |
| CN (2) | CN102028953B (pl) |
| AU (2) | AU2005215254B2 (pl) |
| CA (2) | CA2556248C (pl) |
| DK (2) | DK1718338T3 (pl) |
| ES (2) | ES2544652T3 (pl) |
| HR (1) | HRP20150828T8 (pl) |
| HU (1) | HUE025292T2 (pl) |
| ME (1) | ME02251B (pl) |
| NZ (1) | NZ549139A (pl) |
| PL (1) | PL1718338T3 (pl) |
| PT (1) | PT1718338E (pl) |
| RS (1) | RS54149B1 (pl) |
| SG (3) | SG135174A1 (pl) |
| SI (1) | SI1718338T1 (pl) |
| WO (1) | WO2005079854A1 (pl) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004249172A1 (en) | 2003-06-24 | 2004-12-29 | Baxter International Inc. | Specific delivery of drugs to the brain |
| US8986736B2 (en) | 2003-06-24 | 2015-03-24 | Baxter International Inc. | Method for delivering particulate drugs to tissues |
| PL1718338T3 (pl) * | 2004-02-02 | 2015-12-31 | Engeneic Molecular Delivery Pty Ltd | Kompozycje oraz sposoby do celowanego dostarczania leku in vitro oraz in vivo do ssaczych komórek poprzez bakteriopochodne nienaruszone minikomórki |
| RU2006144851A (ru) | 2004-06-15 | 2008-06-20 | Бакстер Интернэшнл Инк. (Us) | Применение терапевтических средств ex-vivo в виде твердых микрочастиц |
| CN101072876B (zh) | 2004-08-26 | 2012-11-28 | 恩杰内克分子递送有限公司 | 通过细菌性来源的完整小细胞向哺乳动物细胞递送功能性核酸 |
| DK2865755T3 (en) | 2007-03-30 | 2017-05-15 | Engeneic Molecular Delivery Pty Ltd | BACTERIAL DERIVATIVE INTACT MINICELLS WITH REGULATORY RNA |
| US8282930B2 (en) | 2007-09-24 | 2012-10-09 | The University Of Queensland | Molecular delivery vehicle |
| KR20190085187A (ko) | 2008-01-22 | 2019-07-17 | 아라임 파마슈티칼즈, 인크. | 조직 손상 관련 질환 및 장애를 예방 및 치료하기 위한 조직 보호 펩티드 및 펩티드 유사체 |
| CN101965195A (zh) | 2008-03-05 | 2011-02-02 | 巴克斯特国际公司 | 用于药物投送的组合物和方法 |
| KR101813824B1 (ko) | 2008-06-25 | 2017-12-29 | 벡션 테라퓨틱스 엘엘씨 | 조절된 유전자 자살 메커니즘 조성물 및 방법 |
| US10952965B2 (en) | 2009-05-15 | 2021-03-23 | Baxter International Inc. | Compositions and methods for drug delivery |
| KR101314868B1 (ko) | 2009-07-01 | 2013-10-08 | 주식회사이언메딕스 | 포유류의 유핵세포에서 유래된 마이크로베시클 및 이의 용도 |
| IT1401457B1 (it) * | 2010-06-11 | 2013-07-26 | Fond I R C C S Istituto Neurologico Carlo Besta | Carrier di tipo cellulare per il trasporto mirato di almeno una molecola e/o almeno un composto molecolare ad almeno una cellula bersaglio in un mammifero umano o non umano |
| US9149542B2 (en) | 2010-07-01 | 2015-10-06 | Aeon Medix Inc. | Microvesicles derived from cell protoplast and use thereof |
| AU2012217728B2 (en) | 2011-02-15 | 2017-04-27 | Vaxiion Therapeutics, Llc | Therapeutic compositions and methods for antibody and Fc-containing targeting molecule-based targeted delivery of bioactive molecules by bacterial minicells |
| SG11201403062YA (en) * | 2011-12-13 | 2014-07-30 | Engeneic Molecular Delivery Pty Ltd | Bacterially derived, intact minicells for delivery of therapeutic agents to brain tumors |
| EP3750562A1 (en) | 2012-10-02 | 2020-12-16 | Vaxiion Therapeutics, LLC | Immunomodulatory minicells and methods of use |
| GB2521071A (en) * | 2012-10-03 | 2015-06-10 | Waters Technologies Corp | Rapid analysis of steroids and steroid derivatives |
| CA2900454A1 (en) * | 2013-02-07 | 2014-08-14 | Glaxosmithkline Biologicals Sa | Pharmaceutical compositions comprising vesicles |
| US10314916B2 (en) | 2013-06-11 | 2019-06-11 | House Wellness Foods Corporation | Carrier for delivery of substance to phagocytes |
| TWI737576B (zh) | 2013-10-04 | 2021-09-01 | 澳大利亞商安珍尼Ic分子輸送私人有限公司 | 使用藥物裝載之雙特異性配位體標靶的微型細胞與干擾素-γ的組合式腫瘤治療 |
| CN106999444B (zh) * | 2014-10-03 | 2023-12-12 | 安吉尼科分子传输公司 | 完整的细菌衍生的囊泡对小分子化合物的增强装载 |
| CN104388459B (zh) * | 2014-10-29 | 2017-03-08 | 四川农业大学 | 使细菌自主产微细胞的方法及一株自产微细胞细菌突变株 |
| KR101708424B1 (ko) | 2015-03-04 | 2017-02-20 | 전남대학교산학협력단 | 코리네박테리움 속 박테리아 및 이로부터 유래된 미니셀 그리고 이의 용도 |
| JP6824960B2 (ja) | 2015-08-04 | 2021-02-03 | バキシオン セラピューティクス,リミテッド ライアビリティ カンパニー | 細菌由来ミニ細胞型バイオ医薬品の電離放射線照射滅菌およびその使用方法 |
| KR101858840B1 (ko) * | 2016-01-15 | 2018-05-16 | 단국대학교 천안캠퍼스 산학협력단 | 집먼지진드기 유래 알레르겐에 의한 과민반응 면역조절제 |
| US10940112B2 (en) | 2016-05-04 | 2021-03-09 | L.E.A.F. Holdings Group Llc | Targeted liposomal gemcitabine compositions and methods thereof |
| CA3039010A1 (en) | 2016-10-06 | 2018-04-12 | Engeneic Molecular Delivery Pty Ltd | Bacterial minicells for delivering nucleic acid adjuvants and methods of using the same |
| EP3649242A2 (en) | 2017-07-06 | 2020-05-13 | National University of Singapore | Methods of inhibiting cell proliferation and mettl8 activity |
| WO2019204154A1 (en) | 2018-04-18 | 2019-10-24 | Reyoung Corporation | Compositions and methods for treating liver cancer |
| WO2019217164A1 (en) | 2018-05-09 | 2019-11-14 | Reyoung Corporation | Compositions and methods for treating cancer and other diseases |
| WO2020021437A1 (en) | 2018-07-23 | 2020-01-30 | Engeneic Molecular Delivery Pty Ltd | Compositions comprising bacterially derived minicells and methods of using the same |
| SG11202105822WA (en) * | 2018-12-10 | 2021-06-29 | Flagship Pioneering Innovations Vi Llc | Achromosomal dynamic active systems |
| JP7548911B2 (ja) | 2019-01-04 | 2024-09-10 | エンジーンアイシー モレキュラー デリバリー ピーティーワイ リミテッド | 腫瘍性疾患の治療のためのカプセル化グリコリピド抗原 |
| EP3952645A4 (en) * | 2019-04-08 | 2023-08-23 | University Of Massachusetts | Localization of payload delivery systems to tumor sites via beacon cell targeting |
| US20220202950A1 (en) * | 2019-05-01 | 2022-06-30 | Engeneic Molecular Delivery Pty Ltd | Compositions comprising bacterially derived intact minicells for theranostic applications |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| US12537071B1 (en) | 2020-07-22 | 2026-01-27 | David Gordon Bermudes | Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins |
| CN114053430A (zh) * | 2020-07-29 | 2022-02-18 | 深圳先进技术研究院 | 一种负载纳米载药颗粒的细菌及其制备方法和应用 |
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| CA1270198A (en) | 1984-08-08 | 1990-06-12 | Marcel B. Bally | Encapsulation of antineoplastic agents in liposomes |
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| US5800833A (en) | 1995-02-27 | 1998-09-01 | University Of British Columbia | Method for loading lipid vesicles |
| DE69632859T2 (de) | 1995-04-18 | 2005-07-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Verfahren zur Arzneistoffbehandlung von Liposomen Zusammensetzung |
| US5837282A (en) | 1996-10-30 | 1998-11-17 | University Of British Columbia | Ionophore-mediated liposome loading |
| WO2000063364A2 (en) | 1999-04-21 | 2000-10-26 | American Home Products Corporation | Methods and compositions for inhibiting the function of polynucleotide sequences |
| US6635448B2 (en) | 2000-08-21 | 2003-10-21 | Clonexdevelopment, Inc. | Methods and compositions for increasing protein yield from a cell culture |
| IL157794A0 (en) | 2001-03-07 | 2004-03-28 | Childrens Medical Center | Method to screen peptide display libraries using minicell display |
| US7011946B2 (en) | 2001-05-22 | 2006-03-14 | Trustees Of Tufts College | In vivo assay for identification of antimicrobial agents |
| US20030194798A1 (en) | 2001-05-24 | 2003-10-16 | Surber Mark W. | Minicell compositions and methods |
| US20030166099A1 (en) * | 2001-06-05 | 2003-09-04 | Sabbadini Roger A. | Minicells comprising membrane proteins |
| ATE541940T1 (de) * | 2001-10-15 | 2012-02-15 | Engeneic Molecular Delivery Pty Ltd | Intakte minizellen als vektoren für dna-transfer und gentherapie in vitro und in vivo |
| AU2002318168B2 (en) * | 2002-02-25 | 2007-12-13 | Vaxiion Therapeutics, Llc | Minicell compositions and methods |
| US20030203481A1 (en) * | 2002-02-25 | 2003-10-30 | Surber Mark W. | Conjugated minicells |
| US20030207833A1 (en) | 2002-02-25 | 2003-11-06 | Neil Berkley | Pharmaceutical compositions with minicells |
| US7611885B2 (en) | 2003-06-24 | 2009-11-03 | Engeneic Molecular Delivery Pty, Ltd. | Pharmaceutically compatible method for purifying intact bacterial minicells |
| NZ547983A (en) | 2003-12-09 | 2009-05-31 | Engeneic Molecular Delivery Pty Ltd | Targeted gene delivery to non-phagocytic mammalian cells via bacterially derived intact minicells |
| PL1718338T3 (pl) | 2004-02-02 | 2015-12-31 | Engeneic Molecular Delivery Pty Ltd | Kompozycje oraz sposoby do celowanego dostarczania leku in vitro oraz in vivo do ssaczych komórek poprzez bakteriopochodne nienaruszone minikomórki |
| CN101072876B (zh) | 2004-08-26 | 2012-11-28 | 恩杰内克分子递送有限公司 | 通过细菌性来源的完整小细胞向哺乳动物细胞递送功能性核酸 |
| EP2270136A1 (en) | 2004-12-17 | 2011-01-05 | Beth Israel Deaconess Medical Center | Compositions for bacterial mediated gene silencing and methods of using same |
| CN101505768B (zh) | 2006-06-23 | 2013-11-06 | 因詹尼克分子递送控股有限公司 | 通过完整的死亡细菌细胞将药物、治疗性核酸和功能性核酸靶向递送至哺乳动物细胞 |
-
2005
- 2005-01-27 PL PL05702361T patent/PL1718338T3/pl unknown
- 2005-01-27 EP EP20050702361 patent/EP1718338B1/en not_active Expired - Lifetime
- 2005-01-27 EP EP15162946.6A patent/EP2992901B1/en not_active Expired - Lifetime
- 2005-01-27 RS RS20150509A patent/RS54149B1/sr unknown
- 2005-01-27 SG SG200705647-6A patent/SG135174A1/en unknown
- 2005-01-27 HR HRP20150828TT patent/HRP20150828T8/hr unknown
- 2005-01-27 WO PCT/IB2005/000204 patent/WO2005079854A1/en not_active Ceased
- 2005-01-27 DK DK05702361.6T patent/DK1718338T3/en active
- 2005-01-27 ES ES05702361.6T patent/ES2544652T3/es not_active Expired - Lifetime
- 2005-01-27 CA CA2556248A patent/CA2556248C/en not_active Expired - Lifetime
- 2005-01-27 CA CA2788707A patent/CA2788707C/en not_active Expired - Lifetime
- 2005-01-27 SG SG201100772-1A patent/SG169373A1/en unknown
- 2005-01-27 CN CN2010105992452A patent/CN102028953B/zh not_active Expired - Lifetime
- 2005-01-27 CN CN2005800068041A patent/CN1925873B/zh not_active Expired - Lifetime
- 2005-01-27 PT PT57023616T patent/PT1718338E/pt unknown
- 2005-01-27 ES ES15162946T patent/ES2765426T3/es not_active Expired - Lifetime
- 2005-01-27 ME MEP-2015-509A patent/ME02251B/me unknown
- 2005-01-27 DK DK15162946.6T patent/DK2992901T3/da active
- 2005-01-27 SG SG200705648-4A patent/SG135175A1/en unknown
- 2005-01-27 JP JP2006551944A patent/JP5060787B2/ja not_active Expired - Lifetime
- 2005-01-27 NZ NZ549139A patent/NZ549139A/en not_active IP Right Cessation
- 2005-01-27 AU AU2005215254A patent/AU2005215254B2/en not_active Expired
- 2005-01-27 HU HUE05702361A patent/HUE025292T2/en unknown
- 2005-01-27 SI SI200531990T patent/SI1718338T1/sl unknown
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2010
- 2010-02-05 AU AU2010200599A patent/AU2010200599B2/en not_active Expired
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2011
- 2011-04-22 JP JP2011096273A patent/JP5571031B2/ja not_active Expired - Lifetime
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2014
- 2014-04-09 US US14/249,214 patent/US9867785B2/en active Active
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2018
- 2018-01-12 US US15/870,000 patent/US10799461B2/en not_active Expired - Fee Related
- 2018-06-05 US US16/000,480 patent/US20180280311A1/en not_active Abandoned
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