PL1737859T3 - Nowa krystaliczna forma kwasu 8-cyjano-1-cyklopropylo-7-(1S,6S-2,8-diazabicyklo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-okso-3-chinolino-karboksylowego - Google Patents

Nowa krystaliczna forma kwasu 8-cyjano-1-cyklopropylo-7-(1S,6S-2,8-diazabicyklo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-okso-3-chinolino-karboksylowego

Info

Publication number
PL1737859T3
PL1737859T3 PL05716236T PL05716236T PL1737859T3 PL 1737859 T3 PL1737859 T3 PL 1737859T3 PL 05716236 T PL05716236 T PL 05716236T PL 05716236 T PL05716236 T PL 05716236T PL 1737859 T3 PL1737859 T3 PL 1737859T3
Authority
PL
Poland
Prior art keywords
nonan
diazabicyclo
cyclopropyl
dihydro
oxo
Prior art date
Application number
PL05716236T
Other languages
English (en)
Inventor
Hubert Rast
Iris Heep
Alfons Grunenberg
Werner Hallenbach
Jordi Benet-Buchholz
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of PL1737859T3 publication Critical patent/PL1737859T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PL05716236T 2004-04-01 2005-03-19 Nowa krystaliczna forma kwasu 8-cyjano-1-cyklopropylo-7-(1S,6S-2,8-diazabicyklo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-okso-3-chinolino-karboksylowego PL1737859T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004015981A DE102004015981A1 (de) 2004-04-01 2004-04-01 Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
EP05716236A EP1737859B1 (de) 2004-04-01 2005-03-19 Neue kristalline form von 8-cyan-1-cyclopropyl-7-(1s,6s-2,8-diazabicyclo¬4.3.0 nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
PCT/EP2005/002953 WO2005097789A1 (de) 2004-04-01 2005-03-19 Neue kristalline form von 8-cyan-1-cyclopropyl-7-(1s,6s-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure

Publications (1)

Publication Number Publication Date
PL1737859T3 true PL1737859T3 (pl) 2010-04-30

Family

ID=34962324

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05716236T PL1737859T3 (pl) 2004-04-01 2005-03-19 Nowa krystaliczna forma kwasu 8-cyjano-1-cyklopropylo-7-(1S,6S-2,8-diazabicyklo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-okso-3-chinolino-karboksylowego

Country Status (31)

Country Link
US (1) US7977484B2 (pl)
EP (1) EP1737859B1 (pl)
JP (1) JP5190259B2 (pl)
KR (1) KR101217678B1 (pl)
CN (1) CN100591681C (pl)
AR (2) AR048099A1 (pl)
AT (1) ATE450536T1 (pl)
AU (1) AU2005231918B2 (pl)
BR (1) BRPI0509529B8 (pl)
CA (1) CA2561635C (pl)
CY (2) CY1109762T1 (pl)
DE (3) DE102004015981A1 (pl)
DK (1) DK1737859T3 (pl)
ES (1) ES2335899T3 (pl)
GT (1) GT200500043A (pl)
HR (1) HRP20100097T1 (pl)
IL (1) IL178353A (pl)
MY (1) MY140998A (pl)
NO (1) NO337279B1 (pl)
NZ (1) NZ550226A (pl)
PE (1) PE20060170A1 (pl)
PL (1) PL1737859T3 (pl)
PT (1) PT1737859E (pl)
RU (1) RU2383543C2 (pl)
SI (1) SI1737859T1 (pl)
SV (1) SV2006002070A (pl)
TW (1) TWI350755B (pl)
UA (1) UA84329C2 (pl)
UY (1) UY28828A1 (pl)
WO (1) WO2005097789A1 (pl)
ZA (1) ZA200608072B (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006010642A1 (de) * 2006-03-08 2007-09-27 Bayer Healthcare Aktiengesellschaft Arzneimittelformulierungen, enthaltend Fluorchinolone
DE102006010643A1 (de) 2006-03-08 2007-09-13 Bayer Healthcare Aktiengesellschaft Arzneimittel enthaltend Fluorchinolone
DE102007026550A1 (de) * 2007-06-08 2008-12-11 Bayer Healthcare Ag Extrudate mit verbesserter Geschmacksmaskierung
MX387370B (es) 2017-02-13 2025-03-18 Elanco Animal Health Gmbh Composición líquida que contiene pradofloxacina.
CN115710267A (zh) * 2022-11-30 2023-02-24 天津大学 一种普拉沙星水合物晶体及其制备方法
CN117466886A (zh) * 2023-06-20 2024-01-30 瑞普（天津）生物药业有限公司 一种普拉沙星水合物新晶型及其制备方法与应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19546249A1 (de) * 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
PL186737B1 (pl) 1996-02-23 2004-02-27 Bayer Ag Kwasy 8-cyjano-1-cyklopropylo-7-/2, 8-diazabicyklo [ 4.3.0 ] nonan-8-ylo/-6-fluoro-1,4-dihydro-4-okso-3-chinolinokarboksylowe i ich pochodne, sposób ich wytwarzania, środki medyczne je zawierające i ich zastosowanie do wytwarzania środków medycznychi antybakteryjnych
DE19854356A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908448A1 (de) * 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure
DE19908449A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
US6627646B2 (en) * 2001-07-17 2003-09-30 Sepracor Inc. Norastemizole polymorphs

Also Published As

Publication number Publication date
PT1737859E (pt) 2010-02-03
AU2005231918B2 (en) 2011-05-12
NZ550226A (en) 2009-11-27
NO337279B1 (no) 2016-02-29
RU2006138362A (ru) 2008-05-10
EP1737859B1 (de) 2009-12-02
CY1109762T1 (el) 2014-09-10
DE102004015981A1 (de) 2005-10-20
ZA200608072B (en) 2008-01-08
WO2005097789A1 (de) 2005-10-20
TW200602053A (en) 2006-01-16
TWI350755B (en) 2011-10-21
MY140998A (en) 2010-02-12
BRPI0509529B8 (pt) 2021-05-25
HRP20100097T1 (hr) 2010-04-30
SI1737859T1 (sl) 2010-03-31
JP5190259B2 (ja) 2013-04-24
BRPI0509529A (pt) 2007-09-18
AU2005231918A1 (en) 2005-10-20
CN100591681C (zh) 2010-02-24
ES2335899T3 (es) 2010-04-06
CY2011018I1 (el) 2016-12-14
IL178353A0 (en) 2007-02-11
EP1737859A1 (de) 2007-01-03
UY28828A1 (es) 2005-11-30
CA2561635A1 (en) 2005-10-20
SV2006002070A (es) 2006-03-15
NO20064988L (no) 2006-10-31
ATE450536T1 (de) 2009-12-15
KR20070014157A (ko) 2007-01-31
DE122011100055I1 (de) 2012-03-15
PE20060170A1 (es) 2006-04-13
DE502005008620D1 (de) 2010-01-14
RU2383543C2 (ru) 2010-03-10
UA84329C2 (en) 2008-10-10
US20080125458A1 (en) 2008-05-29
IL178353A (en) 2011-08-31
GT200500043A (es) 2006-02-17
JP2007530614A (ja) 2007-11-01
CA2561635C (en) 2012-10-16
AR105177A2 (es) 2017-09-13
BRPI0509529B1 (pt) 2019-05-21
HK1104537A1 (en) 2008-01-18
CN1938304A (zh) 2007-03-28
AR048099A1 (es) 2006-03-29
KR101217678B1 (ko) 2013-01-02
DK1737859T3 (da) 2010-04-06
US7977484B2 (en) 2011-07-12

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