PL1747269T3 - Rekombinowany enzym o zmienionej wrażliwości na sprzężenie zwrotne - Google Patents

Rekombinowany enzym o zmienionej wrażliwości na sprzężenie zwrotne

Info

Publication number
PL1747269T3
PL1747269T3 PL05742717T PL05742717T PL1747269T3 PL 1747269 T3 PL1747269 T3 PL 1747269T3 PL 05742717 T PL05742717 T PL 05742717T PL 05742717 T PL05742717 T PL 05742717T PL 1747269 T3 PL1747269 T3 PL 1747269T3
Authority
PL
Poland
Prior art keywords
recombinant enzyme
feedback sensitivity
altered feedback
altered
sensitivity
Prior art date
Application number
PL05742717T
Other languages
English (en)
Inventor
Gwénaëlle Bestel-Corre
Michel Chateau
Rainer Martin Figge
Céline Raynaud
Philippe Noel Paul Soucaille
Original Assignee
Evonik Degussa Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Degussa Gmbh filed Critical Evonik Degussa Gmbh
Publication of PL1747269T3 publication Critical patent/PL1747269T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL05742717T 2004-05-12 2005-05-12 Rekombinowany enzym o zmienionej wrażliwości na sprzężenie zwrotne PL1747269T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/IB2004/001901 WO2005111202A1 (en) 2004-05-12 2004-05-12 Recombinant enzyme with altered feedback sensitivity
PCT/EP2005/052180 WO2005108561A2 (en) 2004-05-12 2005-05-12 Recombinant enzyme with altered feedback sensitivity
EP05742717.1A EP1747269B1 (en) 2004-05-12 2005-05-12 Recombinant enzyme with altered feedback sensitivity

Publications (1)

Publication Number Publication Date
PL1747269T3 true PL1747269T3 (pl) 2015-08-31

Family

ID=34957660

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05742717T PL1747269T3 (pl) 2004-05-12 2005-05-12 Rekombinowany enzym o zmienionej wrażliwości na sprzężenie zwrotne

Country Status (8)

Country Link
US (1) US8795990B2 (pl)
EP (1) EP1747269B1 (pl)
JP (1) JP5164566B2 (pl)
CN (1) CN1954067B (pl)
ES (1) ES2535816T3 (pl)
MX (1) MXPA06013125A (pl)
PL (1) PL1747269T3 (pl)
WO (2) WO2005111202A1 (pl)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4110641B2 (ja) 1998-11-17 2008-07-02 味の素株式会社 発酵法によるl−メチオニンの製造法
EP1846564A2 (en) * 2005-02-07 2007-10-24 Metabolic Explorer Method for the enzymatic production of alpha-ketobutyrate
JP5172697B2 (ja) * 2006-01-04 2013-03-27 メタボリック エクスプローラー 硫酸透過酵素の発現が増強された微生物を用いてメチオニンおよびその前駆体ホモセリンまたはスクシニルホモセリンを製造するための方法
KR100905381B1 (ko) * 2006-07-28 2009-06-30 씨제이제일제당 (주) L-메치오닌 전구체 생산 균주 및 상기 l-메치오닌전구체로부터의 l-메치오닌 및 유기산의 생산방법
CN101134948B (zh) * 2006-08-31 2011-12-07 百瑞全球有限公司 S-腺苷甲硫氨酸合成酶突变体、编码该突变体的dna以及突变体的应用
CN103710319B (zh) * 2007-04-11 2015-10-07 Cj第一制糖株式会社 组合物及甲硫氨酸的生产方法
ES2575082T3 (es) 2007-04-11 2016-06-24 Cj Cheiljedang Corporation Composiciones y métodos de producción de metionina
CN102703398B (zh) * 2007-04-11 2014-06-04 Cj第一制糖株式会社 组合物及甲硫氨酸的生产方法
EP2167654A2 (en) * 2007-06-25 2010-03-31 Plant Bioscience Limited Enzymes involved in triterpene synthesis
WO2009043372A1 (en) 2007-10-02 2009-04-09 Metabolic Explorer Increasing methionine yield
US7851180B2 (en) 2008-04-04 2010-12-14 Cj Cheiljedang Corporation Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism
US9005952B2 (en) * 2008-04-04 2015-04-14 Cj Cheiljedang Corporation Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism
WO2010022763A1 (en) * 2008-08-25 2010-03-04 Metabolic Explorer Method for the preparation of 2-hydroxy-isobutyrate
CN102341502B (zh) 2008-12-31 2015-07-01 代谢探索者公司 用于制备二醇的方法
US8283152B2 (en) * 2009-08-28 2012-10-09 Cj Cheiljedang Corporation Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
US8609396B2 (en) * 2009-08-28 2013-12-17 Cj Cheiljedang Corporation Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
FR2951195B1 (fr) 2009-10-14 2014-01-31 Roquette Freres Composition riche en methionine destinee a l'alimentation animale
BR112012012915B1 (pt) 2009-11-30 2020-12-01 Ajinomoto Co., Inc. método para produção de l-cisteína, l-cistina, um derivado das mesmas, ou uma mistura das mesmas
WO2011073738A1 (en) 2009-12-14 2011-06-23 Metabolic Explorer Use of inducible promoters in the production of methionine
MY172018A (en) 2009-12-30 2019-11-12 Metabolic Explorer Sa Strains and method for the production of methionine
JP5819316B2 (ja) 2009-12-30 2015-11-24 メタボリック エクスプローラー コハク酸デヒドロゲナーゼを過剰発現させることによるメチオニンの増産
US8911978B2 (en) 2010-07-02 2014-12-16 Metabolic Explorer Method for the preparation of hydroxy acids
TWI500768B (zh) 2010-07-05 2015-09-21 Metabolic Explorer Sa 由蔗糖製備1,3-丙二醇之方法
WO2012014228A1 (en) 2010-07-28 2012-02-02 Abhishek Narain Singh A method to by-pass allosteric domain activity of an enzyme so as to alter its feedback or feed-forward inhibition or activation
JP5803927B2 (ja) 2010-09-14 2015-11-04 味の素株式会社 含硫アミノ酸生産菌及び含硫アミノ酸の製造法
AR083468A1 (es) * 2010-10-25 2013-02-27 Metabolic Explorer Sa Aumento de la disponibilidad de nadph para la produccion de metionina
DK2657250T3 (en) 2010-12-21 2017-12-11 Cj Cheiljedang Corp Polypeptide variant having homoserine acetyl transferase activity and microorganism expressing this
ES2528495T3 (es) * 2010-12-30 2015-02-10 Metabolic Explorer Producción fermentativa de análogo hidroxi de metionina (MHA)
WO2012090021A1 (en) 2010-12-30 2012-07-05 Metabolic Explorer Recombinant microorganism for the fermentative production of methionine
JP2014087259A (ja) 2011-02-22 2014-05-15 Ajinomoto Co Inc L−システイン生産菌及びl−システインの製造法
US9234223B2 (en) 2011-04-01 2016-01-12 Ajinomoto Co., Inc. Method for producing L-cysteine
EP2695940B1 (en) 2011-04-01 2016-11-30 Ajinomoto Co., Inc. Method for producing l-cysteine
EP2540834A1 (en) 2011-06-29 2013-01-02 Metabolic Explorer Method for the preparation of 1,3-propanediol
EP2766492B1 (en) 2011-10-11 2018-06-06 Metabolic Explorer Fermentative production of prenol
FR2983870B1 (fr) 2011-12-08 2015-07-17 Roquette Freres Composition en methionine destinee a l'alimentation animale
EP2647718A3 (en) 2012-04-06 2014-12-24 Metabolic Explorer Process for producing 5-aminopentanoate empolying a recombinant microorganism
JP2012196222A (ja) * 2012-06-11 2012-10-18 Metabolic Explorer 硫酸透過酵素の発現が増強された微生物を用いてメチオニンおよびその前駆体ホモセリンまたはスクシニルホモセリンを製造するための方法
MY168199A (en) 2012-06-18 2018-10-15 Evonik Degussa Gmbh Recombinant microorganism for the fermentative production of methionine
SI2898086T1 (sl) * 2012-09-19 2019-03-29 F. Hoffmann-La Roche Ag Načini in sestavki za preprečevanje napačnega vključevanja norlevcina v beljakovine
WO2014049382A2 (en) 2012-09-26 2014-04-03 Metabolic Explorer Ethylenediamine fermentative production by a recombinant microorganism
BR112015007916B1 (pt) 2013-05-13 2023-04-04 Ajinomoto Co., Inc Método para produzir l-aminoácido
KR102270626B1 (ko) 2013-08-30 2021-06-30 에보니크 오퍼레이션즈 게엠베하 메티오닌 신타제 활성 및 메티오닌 유출이 개선된 메티오닌 생산용 미생물
ES2694011T3 (es) 2013-10-21 2018-12-17 Ajinomoto Co., Inc. Método para producir L-aminoácido
BR112016008830B1 (pt) 2013-10-23 2023-02-23 Ajinomoto Co., Inc Método para produzir uma substância alvo
WO2016034536A1 (en) 2014-09-01 2016-03-10 Metabolic Explorer Method and microorganism for methionine production by fermentation with improved methionine efflux
CN105505894A (zh) * 2014-09-24 2016-04-20 中国科学院天津工业生物技术研究所 天冬氨酸激酶/高丝氨酸脱氢酶突变体及其应用
SG11201708741YA (en) * 2015-05-06 2017-11-29 Trelys Inc Compositions and methods for biological production of methionine
EP3095868A1 (en) 2015-05-19 2016-11-23 Evonik Degussa GmbH Methionine production
CN107787368A (zh) 2015-07-10 2018-03-09 赢创德固赛有限公司 氨基酸生产
CN108026516A (zh) 2015-08-07 2018-05-11 赢创德固赛有限公司 通过发酵的蛋白硫代羧化物依赖性l-甲硫氨酸生产
MX2018006434A (es) 2015-11-27 2018-09-28 Evonik Degussa Gmbh Metodo para producir l-metionina.
US20180355390A1 (en) 2016-01-08 2018-12-13 Evonik Degussa Gmbh Method to produce L-methionine by a fermentative production
CN105838740B (zh) * 2016-05-03 2020-11-06 湖北大学 一种茶树内生草螺菌制备纳米红色元素硒的方法
CN109415418B (zh) 2016-07-08 2024-02-09 代谢探索者公司 通过包含编码糖磷酸转移酶系统(pts)的基因的微生物发酵产生感兴趣的分子的方法
EP3296404A1 (en) 2016-09-15 2018-03-21 Evonik Degussa GmbH Modified microorganism for production of methionine
JP7066977B2 (ja) 2017-04-03 2022-05-16 味の素株式会社 L-アミノ酸の製造法
EP3856918A1 (en) 2018-09-28 2021-08-04 Ajinomoto Co., Inc. Method for producing l-methionine using a bacterium
WO2020071538A1 (en) 2018-10-05 2020-04-09 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
CN112725251B (zh) * 2019-10-14 2022-07-22 江南大学 一种生产亚精胺的工程菌
CN114107243B (zh) * 2021-12-09 2023-04-07 江南大学 一种甲硫氨酸腺苷转移酶突变体
CN116042561B (zh) * 2022-11-11 2023-10-24 山东理工大学 一种s-腺苷蛋氨酸合成酶突变体及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4110641B2 (ja) * 1998-11-17 2008-07-02 味の素株式会社 発酵法によるl−メチオニンの製造法
JP4622111B2 (ja) * 2001-02-09 2011-02-02 味の素株式会社 L−システイン生産菌及びl−システインの製造法
DE10247437A1 (de) * 2002-10-11 2004-04-29 Consortium für elektrochemische Industrie GmbH Feedback-resistente Homoserin-Transsuccinylasen
DE10249642A1 (de) * 2002-10-24 2004-05-13 Consortium für elektrochemische Industrie GmbH Feedback-resistente Homoserin-Transsuccinylasen mit modifiziertem C-Terminus

Also Published As

Publication number Publication date
CN1954067B (zh) 2011-08-03
ES2535816T3 (es) 2015-05-18
WO2005111202A1 (en) 2005-11-24
WO2005108561A3 (en) 2006-07-20
JP2007536921A (ja) 2007-12-20
US8795990B2 (en) 2014-08-05
EP1747269B1 (en) 2015-03-25
CN1954067A (zh) 2007-04-25
MXPA06013125A (es) 2007-02-14
JP5164566B2 (ja) 2013-03-21
EP1747269A2 (en) 2007-01-31
US20090029424A1 (en) 2009-01-29
WO2005108561A2 (en) 2005-11-17

Similar Documents

Publication Publication Date Title
PL1747269T3 (pl) Rekombinowany enzym o zmienionej wrażliwości na sprzężenie zwrotne
PL2278002T3 (pl) Pankreatyna o zmniejszonej zawartości wirusowej
IL181109A0 (en) Polypeptide variants with altered effector function
IL178885A0 (en) Mutant pneumolysim proteins
DK1829959T3 (da) Rekombinant mikroorganisme
ZA200700895B (en) Polypeptide
PL1928260T3 (pl) Zawierający fitazę granulat enzymowy II
GB2426825B (en) Sensor assembly
TWI366553B (en) Assembly
MX296535B (es) Enzima laccasa novedosa y uso de la misma.
GB2418223B (en) Glazed assembly
GB0415196D0 (en) Polypeptide
GB0402904D0 (en) Polypeptide
AU2006323706A8 (en) Genetically recombinant anti-PERP antibody
GB0402624D0 (en) Assembly
GB0418887D0 (en) Assembly
GB2418699B (en) Glazed assembly
GB0423688D0 (en) Enzyme
AU2004907372A0 (en) Recombinant expression
GB0415989D0 (en) Assembly polypeptide
GB0515510D0 (en) Lipase polypeptide
GB0511810D0 (en) Lipase polypeptide
PL371235A1 (pl) Alkomato-oświetlacz
GB2442829B (en) Glazed assembly
GB0400605D0 (en) Polypeptide