PL1763374T3 - Pasta twardniejąca in situ, jej wytwarzanie i zastosowanie - Google Patents

Pasta twardniejąca in situ, jej wytwarzanie i zastosowanie

Info

Publication number
PL1763374T3
PL1763374T3 PL05751734T PL05751734T PL1763374T3 PL 1763374 T3 PL1763374 T3 PL 1763374T3 PL 05751734 T PL05751734 T PL 05751734T PL 05751734 T PL05751734 T PL 05751734T PL 1763374 T3 PL1763374 T3 PL 1763374T3
Authority
PL
Poland
Prior art keywords
manufacturing
hardening paste
situ hardening
situ
paste
Prior art date
Application number
PL05751734T
Other languages
English (en)
Inventor
Klaus Hellerbrand
Michael Siedler
Andreas Schütz
Cornelius Pompe
Wolfgang Friess
Original Assignee
Scil Tech Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scil Tech Gmbh filed Critical Scil Tech Gmbh
Publication of PL1763374T3 publication Critical patent/PL1763374T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/446Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/502Plasticizers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools for implanting artificial joints
    • A61F2/4601Special tools for implanting artificial joints for introducing bone substitute, for implanting bone graft implants or for compacting them in the bone cavity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2817Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30062(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30581Special structural features of bone or joint prostheses not otherwise provided for having a pocket filled with fluid, e.g. liquid
    • A61F2002/30583Special structural features of bone or joint prostheses not otherwise provided for having a pocket filled with fluid, e.g. liquid filled with hardenable fluid, e.g. curable in-situ
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30756Cartilage endoprostheses
    • A61F2002/30766Scaffolds for cartilage ingrowth and regeneration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0085Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof hardenable in situ, e.g. epoxy resins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00179Ceramics or ceramic-like structures
    • A61F2310/00293Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/25Peptides having up to 20 amino acids in a defined sequence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • A61L2300/414Growth factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/43Hormones, e.g. dexamethasone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL05751734T 2004-06-09 2005-06-09 Pasta twardniejąca in situ, jej wytwarzanie i zastosowanie PL1763374T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04013668A EP1604693A1 (en) 2004-06-09 2004-06-09 In situ forming scaffold, its manufacturing and use
EP05751734A EP1763374B1 (en) 2004-06-09 2005-06-09 In situ hardening paste, its manufacturing and use
PCT/EP2005/006204 WO2005120595A2 (en) 2004-06-09 2005-06-09 In situ hardening paste, its manufacture and use

Publications (1)

Publication Number Publication Date
PL1763374T3 true PL1763374T3 (pl) 2012-10-31

Family

ID=34925319

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05751734T PL1763374T3 (pl) 2004-06-09 2005-06-09 Pasta twardniejąca in situ, jej wytwarzanie i zastosowanie

Country Status (9)

Country Link
US (1) US20090048145A1 (pl)
EP (3) EP1604693A1 (pl)
JP (1) JP4644252B2 (pl)
CA (1) CA2569744C (pl)
DK (1) DK1763374T3 (pl)
ES (2) ES2429889T3 (pl)
PL (1) PL1763374T3 (pl)
PT (1) PT1763374E (pl)
WO (1) WO2005120595A2 (pl)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040260398A1 (en) * 2003-02-10 2004-12-23 Kelman David C. Resorbable devices
US7955616B2 (en) 2003-09-23 2011-06-07 Orthocon, Inc. Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects
GB0329654D0 (en) * 2003-12-23 2004-01-28 Smith & Nephew Tunable segmented polyacetal
EP1879525B8 (en) * 2005-05-11 2017-03-01 Hermann Mayr Implant for ligament reconstrction or bone reconstruction
CA2619571A1 (en) * 2005-08-18 2007-02-22 Smith & Nephew, Plc High strength devices and composites
US8852638B2 (en) 2005-09-30 2014-10-07 Durect Corporation Sustained release small molecule drug formulation
WO2007068489A2 (en) * 2005-12-14 2007-06-21 Scil Technology Gmbh A moldable biomaterial for bone regeneration
EP1872807A1 (en) * 2006-06-30 2008-01-02 Scil Technology GmbH Biomaterial containing degradation stabilized polymer
JP2008035981A (ja) * 2006-08-03 2008-02-21 Gc Corp ペースト状骨補填材
DE102006037362B3 (de) * 2006-08-09 2007-09-20 Heraeus Kulzer Gmbh Knochenersatzmaterial
GB0618963D0 (en) * 2006-09-26 2006-11-08 Ucl Business Plc Formulations and composites with reactive fillers
ES2708851T3 (es) * 2006-10-06 2019-04-11 Bionet Pharma Gmbh Un implante del núcleo pulposo espinal
CA2679365C (en) * 2006-11-30 2016-05-03 Smith & Nephew, Inc. Fiber reinforced composite material
AU2007234612B2 (en) 2006-12-14 2013-06-27 Johnson & Johnson Regenerative Therapeutics, Llc Protein stabilization formulations
CN100427152C (zh) * 2006-12-26 2008-10-22 四川国纳科技有限公司 多孔类骨磷灰石/聚酰胺复合材料的制备方法
EP2142353A1 (en) 2007-04-18 2010-01-13 Smith & Nephew PLC Expansion moulding of shape memory polymers
ATE547129T1 (de) 2007-04-19 2012-03-15 Smith & Nephew Inc Multimodale formgedächtnis-polymere
JP5680957B2 (ja) 2007-04-19 2015-03-04 スミス アンド ネフュー インコーポレーテッドSmith & Nephew,Inc. グラフト固定
JP2010531807A (ja) 2007-05-25 2010-09-30 トルマー セラピューティクス, インコーポレイテッド リスペリドン化合物の徐放送達製剤
ES2400457T3 (es) 2007-06-06 2013-04-10 Innotere Gmbh Material de implante a base de un cemento hidráulico y utilización del mismo
US7678764B2 (en) 2007-06-29 2010-03-16 Johnson & Johnson Regenerative Therapeutics, Llc Protein formulations for use at elevated temperatures
GB2451451A (en) * 2007-07-30 2009-02-04 Inion Ltd Osteogenic compounds
US20100098761A1 (en) * 2007-08-03 2010-04-22 University Of Massachusetts Medical School Polymer Compositions For Biomedical And Material Applications
US8058237B2 (en) 2007-08-07 2011-11-15 Advanced Technologies & Regenerative Medicine, LLC Stable composition of GDF-5 and method of storage
WO2009029049A1 (en) * 2007-08-30 2009-03-05 National University Of Singapore A bone and/or dental cement composition and uses thereof
US20090061002A1 (en) * 2007-09-05 2009-03-05 Venbrocks Rudolf A Calcium phospate based delivery of growth and differentiation factors to compromised bone
CA2706512C (en) * 2008-02-08 2013-12-24 Colgate-Palmolive Company Compositions and devices
WO2009129101A1 (en) 2008-04-14 2009-10-22 Advanced Technologies And Regenerative Medicine, Llc Liquid buffered gdf-5 formulations
GB0813659D0 (en) * 2008-07-25 2008-09-03 Smith & Nephew Fracture putty
CN202288967U (zh) * 2008-11-19 2012-07-04 穆尼尔·萨洛芒 用于导向骨再生的阻隔物
US20100226956A1 (en) * 2009-03-06 2010-09-09 Per Kjellin Production of moldable bone substitute
CA2784533C (en) * 2009-12-18 2016-02-09 Howmedica Osteonics Corp. Post irradiation shelf-stable dual paste direct injectable bone cement precursor systems and methods of making same
JP5669050B2 (ja) * 2010-01-15 2015-02-12 国立大学法人島根大学 骨セメント
US9272044B2 (en) 2010-06-08 2016-03-01 Indivior Uk Limited Injectable flowable composition buprenorphine
GB2513060B (en) 2010-06-08 2015-01-07 Rb Pharmaceuticals Ltd Microparticle buprenorphine suspension
US8614190B2 (en) 2010-06-30 2013-12-24 Industrial Technology Research Institute Thermal responsive composition for treating bone diseases
EP2637983B1 (en) 2010-11-10 2018-12-26 Stryker European Holdings I, LLC Process for the preparation of a polymeric bone foam
JP5890100B2 (ja) * 2011-02-09 2016-03-22 雪印メグミルク株式会社 皮膚コラーゲン産生促進剤
WO2012123028A1 (en) * 2011-03-16 2012-09-20 Kuros Biosurgery Ag Pharmaceutical formulation for use in spinal fusion
KR101686683B1 (ko) * 2011-07-15 2016-12-15 단국대학교 산학협력단 인산 칼슘 시멘트의 다공성 스캐폴드 제조방법
EP2768543B1 (de) * 2011-10-19 2018-05-30 InnoTERE GmbH Zubereitung zur herstellung eines implantats
US9539069B2 (en) 2012-04-26 2017-01-10 Zimmer Dental, Inc. Dental implant wedges
US9554877B2 (en) 2012-07-31 2017-01-31 Zimmer, Inc. Dental regenerative device made of porous metal
CN103768657A (zh) * 2012-10-24 2014-05-07 上海交通大学医学院附属第九人民医院 冻干海藻糖磷酸钙bmp-2缓释材料及其制备方法
US10137223B2 (en) 2013-03-14 2018-11-27 Lifenet Health Aligned fiber and method of use thereof
CN103272285B (zh) * 2013-05-24 2014-12-03 华南理工大学 可全降解生物材料及其制备方法
EP3031441B1 (en) * 2013-08-06 2021-02-03 Kuraray Noritake Dental Inc. Curable calcium phosphate composition for dental material
CN103467782B (zh) * 2013-09-22 2015-08-19 山东力扬塑业有限公司 一种可生物降解的塑料及其制备方法
CN103690991B (zh) * 2013-12-17 2015-09-30 李克尊 一种软骨修复支架材料的制备方法
GB201404139D0 (en) 2014-03-10 2014-04-23 Rb Pharmaceuticals Ltd Sustained release buprenorphine solution formulations
WO2016140626A1 (en) * 2015-03-04 2016-09-09 Agency For Science, Technology And Research Composite material for drug delivery
EP3350204A2 (en) 2015-09-18 2018-07-25 BioNet Pharma GmbH Improvement of expression and folding in the manufacturing process of cd-rap by using a cd-rap precursor protein
CN106620883A (zh) * 2016-12-09 2017-05-10 苏州艾博迈尔新材料有限公司 一种组织工程三维多孔支架及其制备方法
EP3624730A4 (en) 2017-05-16 2021-04-14 Embody Inc. COMPOSITIONS OF BIOPOLYMERS, SCAFFOLDING AND DEVICES
WO2018227293A1 (en) * 2017-06-13 2018-12-20 The University Of British Columbia Polymeric paste compositions for drug delivery
WO2019084209A1 (en) 2017-10-24 2019-05-02 Embody Llc BIOPOLYMER SCAFFOLDING IMPLANTS AND METHODS OF MAKING SAME
RU2681916C1 (ru) * 2017-11-22 2019-03-13 Государственное бюджетное учреждение здравоохранения Московской области "Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского" (ГБУЗ МО МОНИКИ им. М.Ф. Владимирского) Способ пластики дефектов трахеогортанного сегмента
CN107988302B (zh) * 2018-01-23 2020-11-13 吉林省吉诺生物工程有限责任公司 一种鹿瓜多肽的制备方法及鹿瓜多肽在制备特殊医学用途食品中的应用
CN108273131B (zh) * 2018-03-19 2021-07-27 深圳市中科海世御生物科技有限公司 一种复合骨水泥、制备方法及其应用和一种骨修复材料
EP3572102B1 (en) * 2018-05-21 2021-02-24 OssDsign AB Two-paste cement-forming compositions
EP3861071A4 (en) 2018-10-04 2022-07-20 Fardanov, Aleksandra Polyvinyl chloride-free lipophilic polymer based aromatized plastisol
CN113557008A (zh) 2018-10-29 2021-10-26 弗劳恩霍夫应用研究促进协会 具有持续活性的四环素类络合物
JP7686561B2 (ja) 2019-02-01 2025-06-02 エンボディ,インコーポレイテッド マイクロフルイディック押出
CN111110929B (zh) * 2020-02-15 2020-12-22 深圳脉动医学技术有限公司 一种高生物安全性心脏支架及其制造方法
CN111821513A (zh) * 2020-08-14 2020-10-27 南方科技大学 一种促进软骨形成的复合水凝胶及其制备方法和应用
CN116251235A (zh) * 2022-12-14 2023-06-13 中国人民解放军空军军医大学 多孔骨引导/诱导自固化磷酸钙复合材料及其制备方法
EP4599842A1 (en) * 2024-02-09 2025-08-13 Association Institut de Myologie Pegylated gdf5 protein
CN119912274B (zh) * 2025-04-07 2025-06-27 成都贝雅医疗科技有限公司 一种表面包覆改性的磷酸钙微球及其制备方法

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0622567B2 (ja) * 1986-12-16 1994-03-30 大日本塗料株式会社 医科用または歯科用セメント組成物
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5702716A (en) 1988-10-03 1997-12-30 Atrix Laboratories, Inc. Polymeric compositions useful as controlled release implants
US5487897A (en) * 1989-07-24 1996-01-30 Atrix Laboratories, Inc. Biodegradable implant precursor
US5324519A (en) 1989-07-24 1994-06-28 Atrix Laboratories, Inc. Biodegradable polymer composition
DE4029969A1 (de) * 1989-09-21 1991-04-04 Asahi Optical Co Ltd Verfahren zur herstellung von knochenprothesen
EP0470305A1 (en) * 1990-08-07 1992-02-12 Osteotech, Inc., Osteoprosthetic implant
JPH0523388A (ja) * 1991-07-18 1993-02-02 Mitsubishi Materials Corp リン酸カルシウムポーラスセメント
JP2686684B2 (ja) * 1991-08-27 1997-12-08 寅雄 大塚 水酸化アパタイトを充填し生体内溶解性繊維により編機されたチューブ網編成物
AU2605592A (en) 1991-10-15 1993-04-22 Atrix Laboratories, Inc. Polymeric compositions useful as controlled release implants
US5281265A (en) * 1992-02-03 1994-01-25 Liu Sung Tsuen Resorbable surgical cements
US5522893A (en) * 1993-03-12 1996-06-04 American Dental Association Health Foundation Calcium phosphate hydroxyapatite precursor and methods for making and using the same
US5569468A (en) * 1994-02-17 1996-10-29 Modi; Pankaj Vaccine delivery system for immunization, using biodegradable polymer microspheres
DK0754032T3 (da) 1994-04-08 2002-04-02 Atrix Lab Inc Flydende frigivelsessammensætninger
AU1287895A (en) * 1994-10-03 1996-04-26 Otogen Corporation Differentially biodegradable biomedical implants
US5764619A (en) * 1995-04-07 1998-06-09 Matsushita Electric Industrial Co., Ltd. Optical recording medium having two separate recording layers
US5922253A (en) 1995-05-18 1999-07-13 Alkermes Controlled Therapeutics, Inc. Production scale method of forming microparticles
US6132463A (en) * 1995-05-19 2000-10-17 Etex Corporation Cell seeding of ceramic compositions
US5736152A (en) 1995-10-27 1998-04-07 Atrix Laboratories, Inc. Non-polymeric sustained release delivery system
US20030211157A1 (en) * 1996-05-06 2003-11-13 Simon David Lew Semi-sol delivery blend for water soluble molecules
EP0907721A1 (en) * 1996-05-28 1999-04-14 Brown University Research Foundation Hyaluronan based biodegradable scaffolds for tissue repair
US6953594B2 (en) * 1996-10-10 2005-10-11 Etex Corporation Method of preparing a poorly crystalline calcium phosphate and methods of its use
DE19647853A1 (de) 1996-11-19 1998-05-20 Bioph Biotech Entw Pharm Gmbh Verbindungen mit verbesserter knorpel- und/oder knocheninduzierender Aktivität
JP4177900B2 (ja) * 1997-04-04 2008-11-05 株式会社クラレ 歯周病治療用材料
DE19816858A1 (de) 1998-04-16 1999-10-21 Merck Patent Gmbh Tricalciumphosphathaltige Biozementpasten mit Kohäsionspromotoren
US6143314A (en) 1998-10-28 2000-11-07 Atrix Laboratories, Inc. Controlled release liquid delivery compositions with low initial drug burst
ES2242600T3 (es) * 1999-02-04 2005-11-16 Sdgi Holdings, Inc. Composiciones de pasta osteogenica y sus usos.
WO2002032474A1 (en) * 2000-10-13 2002-04-25 Osteotech, Inc. Method for inducing new bone growth in porous bone sites
US6461631B1 (en) 1999-11-16 2002-10-08 Atrix Laboratories, Inc. Biodegradable polymer composition
US20030158302A1 (en) * 1999-12-09 2003-08-21 Cyric Chaput Mineral-polymer hybrid composition
FR2805747B1 (fr) * 2000-03-01 2003-03-14 Teknimed Procede de preparation d'un materiau pateux phosphocalcique injectable en vue de former un biomateriau apatitique et application chirurgicale ou dentaire
US20040018238A1 (en) * 2001-02-26 2004-01-29 Shukla Atul J Biodegradable vehicles and delivery systems of biolgically active substances
US6949251B2 (en) 2001-03-02 2005-09-27 Stryker Corporation Porous β-tricalcium phosphate granules for regeneration of bone tissue
BR0214275A (pt) 2001-11-19 2004-09-21 Scil Technology Gmbh Dispositivo tendo propriedades osteocondutora e osteoindutora
US7166133B2 (en) * 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
US20040109893A1 (en) * 2002-06-25 2004-06-10 Guohua Chen Sustained release dosage forms of anesthetics for pain management
US6979352B2 (en) * 2002-11-21 2005-12-27 Depuy Acromed Methods of performing embolism-free vertebroplasty and devices therefor
WO2004105825A1 (ja) * 2003-01-10 2004-12-09 Taki Chemical Co., Ltd. 骨形成用生体材料、該材料を含む注入用製剤、及び該材料を調製するためのキット、並びにこれらを用いる骨形成方法
US20040230309A1 (en) * 2003-02-14 2004-11-18 Depuy Spine, Inc. In-situ formed intervertebral fusion device and method

Also Published As

Publication number Publication date
EP2322234A1 (en) 2011-05-18
EP2322234B1 (en) 2013-08-21
WO2005120595A3 (en) 2006-05-26
CA2569744C (en) 2011-03-15
PT1763374E (pt) 2012-08-17
CA2569744A1 (en) 2005-12-22
JP2008501455A (ja) 2008-01-24
WO2005120595A2 (en) 2005-12-22
EP1604693A1 (en) 2005-12-14
ES2429889T3 (es) 2013-11-18
EP1763374A2 (en) 2007-03-21
ES2385212T3 (es) 2012-07-19
DK1763374T3 (da) 2012-09-24
US20090048145A1 (en) 2009-02-19
EP1763374B1 (en) 2012-06-20
JP4644252B2 (ja) 2011-03-02

Similar Documents

Publication Publication Date Title
PL1763374T3 (pl) Pasta twardniejąca in situ, jej wytwarzanie i zastosowanie
IL179942A0 (en) Electrochemical methods, devices, and structures
EP1784163A4 (en) NANOEMULSION, USE THEREOF AND PROCESS FOR PREPARING THE SAME
EP1834097A4 (en) IMPROVED PUMP AND METHOD
ZA200701820B (en) Substituted phenylaminothiazoles and use thereof
EP1748721A4 (en) DISHWASHER AND METHOD
GB2435590B (en) An interleaver and associated methods
EP1737473A4 (en) COMBINATIONS OF LITHIUM AND USES THEREOF
IL176923A0 (en) Structured materials and methods
ZA200709703B (en) Electrode and manufacturing methods
PL1728544T3 (pl) Struktura plastra miodu i sposób jej wytwarzania
PL375645A1 (pl) Zestaw elementu mocującego i wkrętaka, element mocujący i wkrętak do elementu mocującego
GB2419134B (en) Polishing composition and polishing method using the same
IL184062A0 (en) Visco-supplement composition and methods
GB2420122B (en) Polishing composition and polishing method using the same
EP1723158A4 (en) O, O'-AMIDOMALONATE AND N, O-AMIDOMALONATE PLATINUM COMPLEXES
EP1816169A4 (en) FLAME RETARDANT RESIN COMPOSITION, PROCESS FOR PRODUCING THE SAME, PROCESS FOR MOLDING THE SAME
EP1961771A4 (en) BISMUTH HYALURONATE, PREPARATION METHOD AND USE THEREOF
GB0517937D0 (en) Polishing composition and polishing method using the same
GB0403008D0 (en) Composition and method
EP1778082A4 (en) CARBORANYLPORPHYRINS AND USES THEREOF
EP1828718A4 (en) FOR DAILY LIGHTING, PHOTOVOLTAICS AND SOLAR HEATING USEFUL SUNLIGHT HANDLEBAR
TWI367222B (en) Aminoquinoxaline compounds and polyaminoquinoxaline compounds, and use thereof
GB0403491D0 (en) Polypeptides, methods and means
EP1735648A4 (en) BREAKING RIMS, FURNISHINGS AND MATERIALS