PL1765866T3 - Wydzielanie białek osocza lub surowicy - Google Patents

Wydzielanie białek osocza lub surowicy

Info

Publication number
PL1765866T3
PL1765866T3 PL05746285T PL05746285T PL1765866T3 PL 1765866 T3 PL1765866 T3 PL 1765866T3 PL 05746285 T PL05746285 T PL 05746285T PL 05746285 T PL05746285 T PL 05746285T PL 1765866 T3 PL1765866 T3 PL 1765866T3
Authority
PL
Poland
Prior art keywords
isolation
plasma
serum proteins
serum
proteins
Prior art date
Application number
PL05746285T
Other languages
English (en)
Inventor
Allan Otto Fog Lihme
Original Assignee
Therapure Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therapure Biopharma Inc filed Critical Therapure Biopharma Inc
Publication of PL1765866T3 publication Critical patent/PL1765866T3/pl

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
    • B01D15/206—Packing or coating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL05746285T 2004-06-07 2005-06-07 Wydzielanie białek osocza lub surowicy PL1765866T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200400891 2004-06-07
DKPA200401062 2004-07-05
PCT/DK2005/000378 WO2005121163A2 (en) 2004-06-07 2005-06-07 Isolation of plasma or serum proteins
EP05746285.5A EP1765866B1 (en) 2004-06-07 2005-06-07 Isolation of plasma or serum proteins

Publications (1)

Publication Number Publication Date
PL1765866T3 true PL1765866T3 (pl) 2014-06-30

Family

ID=34969001

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05746285T PL1765866T3 (pl) 2004-06-07 2005-06-07 Wydzielanie białek osocza lub surowicy

Country Status (10)

Country Link
US (3) US9624260B2 (pl)
EP (3) EP2277912B1 (pl)
CN (2) CN102924565A (pl)
AU (2) AU2005252296B2 (pl)
BR (1) BRPI0511906B1 (pl)
DK (1) DK1765866T3 (pl)
ES (2) ES2606078T3 (pl)
PL (1) PL1765866T3 (pl)
PT (1) PT1765866E (pl)
WO (1) WO2005121163A2 (pl)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1664123E (pt) * 2003-09-22 2008-07-16 Kamada Ltd Preparação em larga escala de um inibidor da alfa-1 proteinase e sua utilização
EP1691820A4 (en) 2003-11-08 2010-03-03 Prothera Biolog PREPARATION AND COMPOSITION OF INTER ALPHA HEMMER PROTEINS FROM HUMAN PLASMA FOR THERAPEUTIC USE
WO2005121163A2 (en) 2004-06-07 2005-12-22 Upfront Chromatography A/S Isolation of plasma or serum proteins
BRPI0511893A (pt) * 2004-06-07 2008-01-15 Avt Plasma Ltd processo para isolamento de proteìna
WO2007063129A2 (en) * 2005-12-02 2007-06-07 Novozymes A/S Insolation of peptides , polypeptides and proteins
US9433922B2 (en) * 2007-08-14 2016-09-06 Emd Millipore Corporation Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same
US20120177610A1 (en) 2007-09-19 2012-07-12 Kieu Hoang Manufacturing and Purification Processes of Complex Protein found in Fraction IV to make a separated Apo, Transferrin , and Alpha 1 Anti strepsin (A1AT) or A combined Transferrin / Apo/Human Albumin/A1AT and all new found proteins
CN106928346B (zh) 2008-05-28 2021-09-07 普罗瑟拉生物公司 来自血液的间-α抑制物蛋白的制备和组合物
US20110065900A1 (en) * 2008-05-30 2011-03-17 Ge Healthcare Bio-Science Ab Separation method utilizing polyallylamine ligands
EP2300497B1 (en) * 2008-06-24 2012-08-08 Octapharma AG A process of purifying coagulation factor viii
MX2011001624A (es) 2008-08-21 2011-03-28 Octapharma Ag Factor viii y ix humano producido en forma recombinante.
US8945895B2 (en) 2009-07-31 2015-02-03 Baxter International Inc. Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof
KR101951446B1 (ko) 2010-03-30 2019-02-22 옥타파마 아게 성장 인자 단백질을 정제하는 방법
WO2011121020A1 (en) 2010-03-30 2011-10-06 Octapharma Ag A process for purifying vitamin k dependent proteins such as coagulation factor ix
SG191186A1 (en) 2010-12-15 2013-07-31 Baxter Int Eluate collection using conductivity gradient
FR2977893B1 (fr) * 2011-07-11 2015-02-20 Lab Francais Du Fractionnement Procede de preparation d'un concentre d'immunoglobulines polyvalentes
US8802448B2 (en) 2011-07-27 2014-08-12 Pall Corporation Mixed mode ligands
TW201335181A (zh) * 2012-01-31 2013-09-01 Kieu Hoang ５５種新發現的蛋白質之序列及其應用
CN102532307B (zh) * 2012-02-22 2013-06-12 成都蓉生药业有限责任公司 一种制备人免疫球蛋白的方法
GB201206530D0 (en) * 2012-04-13 2012-05-30 Vivacta Ltd An assay label
US20140031527A1 (en) * 2012-07-27 2014-01-30 Csl Limited Method for polishing albumin
WO2014039987A2 (en) 2012-09-09 2014-03-13 Prothera Biologics, Inc. Treatment of disease using inter-alpha inhibitor proteins
CN102977180B (zh) * 2012-11-06 2016-03-16 中国科学院过程工程研究所 一种综合利用Cohn组分IV的方法
US20140206844A1 (en) 2013-01-18 2014-07-24 Prothera Biologics Methods for isolating blood products from an inter-alpha inhibitor protein-depleted blood product material
CN103130868B (zh) * 2013-03-12 2014-09-17 合肥天麦生物科技发展有限公司 一种蛋白质或多肽的纯化方法
CN104236983A (zh) * 2013-06-14 2014-12-24 中国科学院大连化学物理研究所 溶液样品中含长烷基链的离子液体的去除方法
US9663553B2 (en) * 2014-01-29 2017-05-30 Hemarus Therapeutics Limited Integrated process for the production of therapeutics (human albumin, immunoglobulins, clotting factor VIII and clotting factor IX) from human plasma
US10266561B2 (en) * 2015-09-28 2019-04-23 Kieu Hoang Method for separating proteins from animal or human plasma, or plants, using a pH gradient method
CN106085992A (zh) * 2016-06-16 2016-11-09 武汉中原瑞德生物制品有限责任公司 一种提高人凝血酶原复合物中fⅶ收率的方法
CN109789193A (zh) 2016-09-13 2019-05-21 普罗瑟拉生物公司 使用间α抑制蛋白治疗肺病的方法
EP3615937B1 (en) 2017-04-25 2026-01-28 Prothera Biologics, Inc. Methods for quantifying inter-alpha inhibitor proteins
US11866743B1 (en) 2017-05-31 2024-01-09 Teledyne Flir Detection, Inc. Pharmaceutical formulations, methods for treating chemical warfare agent exposure, and modified biomolecules
EP3651811A1 (en) * 2017-07-10 2020-05-20 Baxalta Incorporated Method for incubating liquids and inactivating viruses
US11918957B2 (en) 2018-12-12 2024-03-05 Donaldson Company, Inc. Affinity membrane and method of preparation
WO2020160505A1 (en) * 2019-02-01 2020-08-06 Ohio State Innovation Foundation Methods of protein purification
CN110215739A (zh) * 2019-07-15 2019-09-10 大连医科大学 一种离子型亲水前处理硅胶材料的制备方法
CN110215740B (zh) * 2019-07-15 2021-05-04 大连医科大学 一种两性离子亲水前处理硅胶材料的制备方法
CN111603802A (zh) * 2020-05-10 2020-09-01 上海灿实工程设备有限公司 一种用于血液制品的吸附罐
CN112409476B (zh) * 2020-08-13 2022-03-29 中元汇吉生物技术股份有限公司 四种血液来源蛋白的纯化方法
JP2025512143A (ja) 2020-11-09 2025-04-17 武田薬品工業株式会社 酸化ケイ素吸着を使用する血漿からのｆｖｉｉｉの精製
CN112250757A (zh) * 2020-11-13 2021-01-22 广东深蓝生物科技有限公司 一种猪血浆中蛋白质的提取纯化方法
CN112827217A (zh) * 2020-12-29 2021-05-25 苏州良辰生物医药科技有限公司 一种层析柱清洗液及其应用
AU2022358209A1 (en) * 2021-09-28 2024-03-07 LIHME PROTEIN SOLUTIONS ApS Improved protein sorption and filtration apparatus
CN116217710B (zh) * 2023-04-23 2025-05-27 华兰生物工程重庆有限公司 一种从血浆中提取分离IgM与凝血因子Ⅶ的方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2390074A (en) 1942-02-09 1945-12-04 Research Corp Protein product and process
US2469193A (en) 1942-02-09 1949-05-03 Research Corp Protein fractionation
US4156681A (en) 1974-03-28 1979-05-29 Plasmesco Ag Process for isolating albumin from blood
JPS57168157A (en) * 1981-02-12 1982-10-16 Asahi Chem Ind Co Ltd High performance liquid chromatography column and analysis method using the same
US4481189A (en) 1982-04-14 1984-11-06 New York Blood Center Inc. Process for preparing sterilized plasma and plasma derivatives
US4749783A (en) * 1986-07-11 1988-06-07 Miles Laboratories, Inc. Viral inactivation and purification of active proteins
US5258503A (en) * 1987-09-08 1993-11-02 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Autoantibody adsorbent and apparatus for removing autoantibodies using the same
US5055485A (en) * 1988-12-02 1991-10-08 New York Blood Center, Inc. Inactivation of viruses in cell- and protein-containing compositions using aryl diol epoxides
DK165090D0 (da) 1990-07-09 1990-07-09 Kem En Tec As Konglomererede partikler
DK52791D0 (da) 1991-03-22 1991-03-22 Kem En Tec As Adsorptionsmatricer
SE9101149D0 (sv) 1991-04-17 1991-04-17 Pharmacia Lkb Biotech Beads for down stream processing
US5502022A (en) 1994-05-16 1996-03-26 Biosepra, Inc. Chromatography adsorbents utilizing mercapto heterocyclic ligands
DK0699687T3 (da) 1994-08-31 2004-04-26 Mitsubishi Pharma Corp Fremgangsmåde til oprensning af rekombinant humant serumalbumin
US5837826A (en) 1995-02-27 1998-11-17 Regents Of The University Of Minnesota Protein adsorption by very dense porous zirconium oxide particles in expanded beds
SE9503926D0 (sv) * 1995-11-07 1995-11-07 Pharmacia Biotech Ab Adsorptionsförfarande och separationsmedium
TW491855B (en) * 1996-08-07 2002-06-21 Csl Ltd Purification of immunoglobulins
US6498236B1 (en) 1996-08-30 2002-12-24 Upfront Chromatography A/S Isolation of immunoglobulins
IL137649A (en) * 1998-02-18 2004-08-31 Genentech Inc Method of adsorption chromatography
US20020104801A1 (en) 1998-04-06 2002-08-08 Nicolas Voute Small dense microporous solid support materials, their preparation,and use for purification of large macromolecules and bioparticles
DE19823814A1 (de) * 1998-05-27 1999-12-02 Octapharma Ag Ziegelbruecke Verfahren zur Trennung und/oder Isolierung von Plasmaproteinen mit annularer Chromatographie
EP1087828B1 (en) 1998-06-18 2008-09-17 Upfront Chromatography A/S Expanded bed adsorption system
CA2350690C (en) 1998-10-31 2008-07-22 Amersham Pharmacia Biotech Ab A chromatographic process utilizing a fluidised bed
DE60033505T2 (de) 1999-03-26 2007-11-22 Upfront Chromatography A/S, Kopenhagen Partikelmaterial für wirbelbettreinigung von biomakromolekülen wie plasmid-dns, chromosomen-dns, rns,virale dns, bakterien und viren
NZ523049A (en) 2000-05-12 2005-09-30 Upfront Chromatography As A bed absorption system
SE0100714D0 (sv) 2000-07-13 2001-02-28 Ap Biotech Ab Reaction vessel and method for distributing fluid in such a vessel
EP1884274A1 (en) 2000-12-29 2008-02-06 Upfront Chromatography A/S Extracorporeal capturing of specific bio-macromolecular entities from extracellular body fluids
DE60203176T2 (de) * 2001-06-01 2006-04-27 Upfront Chromatography A/S, Kopenhagen Fraktionierung von proteinhaltigen mischungen
CN1207064C (zh) * 2002-03-29 2005-06-22 华兰生物工程股份有限公司 一种冻干人纤维蛋白胶的生产工艺
EP1521624A2 (en) 2002-07-11 2005-04-13 Upfront Chromatography A/S An extracorporeal stabilised expanded bed adsorption method for the treatment of sepsis
ATE365463T1 (de) * 2003-03-21 2007-07-15 Upfront Chromatography As Verfahren für volumen mit hohem durchsatz bei der fraktionierung von biomolekülen durch chromatographische systeme
WO2005121163A2 (en) 2004-06-07 2005-12-22 Upfront Chromatography A/S Isolation of plasma or serum proteins
ES2647925T3 (es) * 2011-05-12 2017-12-27 Csl Behring Gmbh Métodos para reducir los eventos adversos causados por preparados farmacéuticos que comprenden proteínas derivadas del plasma

Also Published As

Publication number Publication date
CN102924565A (zh) 2013-02-13
EP1765866B1 (en) 2014-01-08
US20170282095A1 (en) 2017-10-05
EP3127916A1 (en) 2017-02-08
WO2005121163A3 (en) 2006-03-23
BRPI0511906B1 (pt) 2021-11-30
EP2277912B1 (en) 2016-09-28
BRPI0511906A (pt) 2008-01-15
AU2009238344A1 (en) 2009-12-10
ES2606078T3 (es) 2017-03-17
AU2009238344B2 (en) 2012-02-16
AU2005252296A1 (en) 2005-12-22
US9624260B2 (en) 2017-04-18
WO2005121163A2 (en) 2005-12-22
US9428545B2 (en) 2016-08-30
EP2277912A3 (en) 2011-05-04
US20070299251A1 (en) 2007-12-27
CN1972961A (zh) 2007-05-30
CN1972961B (zh) 2012-12-26
DK1765866T3 (en) 2014-03-24
EP1765866A2 (en) 2007-03-28
AU2005252296B2 (en) 2009-08-20
PT1765866E (pt) 2014-04-14
ES2454566T3 (es) 2014-04-10
US20160009757A1 (en) 2016-01-14
EP2277912A2 (en) 2011-01-26

Similar Documents

Publication Publication Date Title
PL1765866T3 (pl) Wydzielanie białek osocza lub surowicy
EP2102355A4 (en) PROTEINS AND PEPTIDES WITH EXTENDED ACTION AND METHODS OF PRODUCTION AND USE THEREOF
DE602005009729D1 (de) System zur zubereitung von getränken
WO2007070538A9 (en) Anti-mn antibodies and methods of using same
PL1715752T3 (pl) Nowy izolat białka rzepaku
IL182626A0 (en) Methods for refolding of recombinant antibodies
PL2322613T3 (pl) Reagenty i sposoby izolacji oczyszczonego RNA
EP1739093B8 (fr) Séparation de protéines plasmatiques
EP1773881A4 (en) Inhibition of macrophage-stimulating protein receptor (RON)
GB0426160D0 (en) Production of proteins
EP1869192A4 (en) FRAME MIXTURE OF ANTIBODIES
GB0426161D0 (en) Protein isolation and purification
IL183106A0 (en) Production of proteins
GB0423974D0 (en) Proteins
IL179901A0 (en) Process for protein isolation
WO2008017017A3 (en) Three-phase partitioning method for purifying a protein
ZA200700167B (en) Process for protein isolation
EP1751174A4 (en) PROTEIN INHIBITORS REGIII, THERAPEUTIC AGENTS AGAINST ASTHMA
EP1739089A4 (en) PROCESS FOR DISINTER SEPARATION
EP1760149A4 (en) PROCESS FOR CONSTRUCTING MODIFIED PROTEIN
AU2004906748A0 (en) Improved Detection of Proteins
AU2004903045A0 (en) Process for Protein Isolation
AU2004902112A0 (en) Identification of placental proteins
AU2004900731A0 (en) Methods of sequence determination
GB0423002D0 (en) Proteins