|
WO2003024430A1
(en)
|
2001-09-21 |
2003-03-27 |
Egalet A/S |
Morphine polymer release system
|
|
EP2957281A1
(en)
|
2001-09-21 |
2015-12-23 |
Egalet Ltd. |
Polymer release system
|
|
CN100553625C
(zh)
|
2002-04-09 |
2009-10-28 |
弗拉梅技术公司 |
活性成分微囊的口服混悬液
|
|
US7776314B2
(en)
|
2002-06-17 |
2010-08-17 |
Grunenthal Gmbh |
Abuse-proofed dosage system
|
|
US8877241B2
(en)
|
2003-03-26 |
2014-11-04 |
Egalet Ltd. |
Morphine controlled release system
|
|
DE10336400A1
(de)
|
2003-08-06 |
2005-03-24 |
Grünenthal GmbH |
Gegen Missbrauch gesicherte Darreichungsform
|
|
DE102005005446A1
(de)
|
2005-02-04 |
2006-08-10 |
Grünenthal GmbH |
Bruchfeste Darreichungsformen mit retardierter Freisetzung
|
|
DE10361596A1
(de)
|
2003-12-24 |
2005-09-29 |
Grünenthal GmbH |
Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
|
|
DE102004032051A1
(de)
|
2004-07-01 |
2006-01-19 |
Grünenthal GmbH |
Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
|
|
US20070048228A1
(en)
|
2003-08-06 |
2007-03-01 |
Elisabeth Arkenau-Maric |
Abuse-proofed dosage form
|
|
US8075872B2
(en)
|
2003-08-06 |
2011-12-13 |
Gruenenthal Gmbh |
Abuse-proofed dosage form
|
|
DE102004032049A1
(de)
|
2004-07-01 |
2006-01-19 |
Grünenthal GmbH |
Gegen Missbrauch gesicherte, orale Darreichungsform
|
|
DE102005005449A1
(de)
|
2005-02-04 |
2006-08-10 |
Grünenthal GmbH |
Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
|
|
US9023400B2
(en)
|
2006-05-24 |
2015-05-05 |
Flamel Technologies |
Prolonged-release multimicroparticulate oral pharmaceutical form
|
|
FR2901478B1
(fr)
*
|
2006-05-24 |
2015-06-05 |
Flamel Tech Sa |
Forme pharmaceutique orale multimicroparticulaire a liberation prolongee
|
|
SA07280459B1
(ar)
|
2006-08-25 |
2011-07-20 |
بيورديو فارما إل. بي. |
أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
|
|
DE102007011485A1
(de)
|
2007-03-07 |
2008-09-11 |
Grünenthal GmbH |
Darreichungsform mit erschwertem Missbrauch
|
|
NZ580972A
(en)
|
2007-06-04 |
2012-02-24 |
Egalet Ltd |
Controlled release pharmaceutical compositions for prolonged effect
|
|
JP5774853B2
(ja)
|
2008-01-25 |
2015-09-09 |
グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング |
医薬投薬形
|
|
MX2010012039A
(es)
|
2008-05-09 |
2010-11-30 |
Gruenenthal Gmbh |
Proceso para la preparacion de una formulacion de polvo intermedia y una forma de dosificacion solida final bajo el uso de un paso de congelacion por rocio.
|
|
WO2010089132A1
(en)
|
2009-02-06 |
2010-08-12 |
Egalet A/S |
Immediate release composition resistant to abuse by intake of alcohol
|
|
EP2445487A2
(en)
|
2009-06-24 |
2012-05-02 |
Egalet Ltd. |
Controlled release formulations
|
|
BR112012001547A2
(pt)
|
2009-07-22 |
2016-03-08 |
Gruenenthal Gmbh |
forma de dosagem farmacêutica extrusada por fusão a quente
|
|
ES2428938T3
(es)
|
2009-07-22 |
2013-11-12 |
Grünenthal GmbH |
Forma de dosificación resistente a la manipulación y estabilizada frente a la oxidación
|
|
US8397733B2
(en)
*
|
2010-01-15 |
2013-03-19 |
Celanese Acetate Llc |
Degradable cigarette filter: pill with multilayered coating
|
|
CN102821757B
(zh)
|
2010-02-03 |
2016-01-20 |
格吕伦塔尔有限公司 |
通过挤出机制备粉末状药物组合物
|
|
WO2011124953A2
(en)
*
|
2010-04-07 |
2011-10-13 |
Lupin Limited |
Controlled release pharmaceutical compositions of tapentadol
|
|
LT3656765T
(lt)
|
2010-07-23 |
2021-06-10 |
Grünenthal GmbH |
3-(3-dimetilamino-1-etil-2-metil-propil)-fenolio druskos arba bendri kristalai
|
|
CN103179956A
(zh)
|
2010-09-02 |
2013-06-26 |
格吕伦塔尔有限公司 |
包含阴离子聚合物的抗破碎剂型
|
|
CN103179954A
(zh)
|
2010-09-02 |
2013-06-26 |
格吕伦塔尔有限公司 |
包含阴离子聚合物的抗破碎剂型
|
|
CA2808219C
(en)
|
2010-09-02 |
2019-05-14 |
Gruenenthal Gmbh |
Tamper resistant dosage form comprising inorganic salt
|
|
MX374468B
(es)
|
2011-03-04 |
2025-03-06 |
Gruenenthal Gmbh |
Composicion farmaceutica acuosa semisolida que contiene tapentadol.
|
|
EA024193B1
(ru)
|
2011-03-04 |
2016-08-31 |
Грюненталь Гмбх |
Фармацевтическая композиция на водной основе, предназначенная для парентерального введения тапентадола
|
|
MX369121B
(es)
|
2011-03-04 |
2019-10-30 |
Gruenenthal Gmbh |
Formulacion farmaceutica acuosa de tapentadol para administracion oral.
|
|
CA2839123A1
(en)
|
2011-07-29 |
2013-02-07 |
Grunenthal Gmbh |
Tamper-resistant tablet providing immediate drug release
|
|
PL2736497T3
(pl)
|
2011-07-29 |
2018-01-31 |
Gruenenthal Gmbh |
Tabletka odporna na ingerencję, zapewniająca natychmiastowe uwalnianie leku
|
|
PE20141171A1
(es)
|
2011-10-06 |
2014-09-21 |
Gruenenthal Chemie |
Forma de dosificacion farmaceutica oral resistente a alteracion comprendiendo agonista opioide y antagonista opioide
|
|
AU2012338872B2
(en)
|
2011-11-17 |
2017-06-22 |
Grünenthal GmbH |
Tamper-resistant oral pharmaceutical dosage form comprising a pharmacologically active ingredient, an opioid antagonist and/or aversive agent, polyalkylene oxide and anionic polymer
|
|
MX356421B
(es)
|
2012-02-28 |
2018-05-29 |
Gruenenthal Gmbh |
Forma de dosificacion resistente a la manipulacion indebida que comprende un compuesto farmacologicamente activo y un polimero anionico.
|
|
US20130225625A1
(en)
|
2012-02-28 |
2013-08-29 |
Grunenthal Gmbh |
Tamper-resistant pharmaceutical dosage form comprising nonionic surfactant
|
|
PL2838512T3
(pl)
|
2012-04-18 |
2018-12-31 |
Grünenthal GmbH |
Farmaceutyczna postać dawkowania odporna na niewłaściwe użycie i odporna na uderzeniowe uwalnianie dawki
|
|
US10064945B2
(en)
|
2012-05-11 |
2018-09-04 |
Gruenenthal Gmbh |
Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
|
|
LT2846835T
(lt)
|
2012-05-11 |
2017-12-27 |
Grünenthal GmbH |
Termiškai suformuota, sugadinimui atspari vaistinė dozavimo forma, turinti cinko
|
|
BR112015000150A2
(pt)
|
2012-07-06 |
2017-06-27 |
Egalet Ltd |
composições farmacêuticas dissuasoras de abuso de liberação controlada
|
|
WO2014106865A1
(en)
*
|
2013-01-07 |
2014-07-10 |
Alkem Laboratories Ltd. |
Abuse-proofed, extended release pharmaceutical composition comprising tapentadol or a pharmaceutically acceptable salt thereof and processes for preparing thereof
|
|
WO2014191396A1
(en)
|
2013-05-29 |
2014-12-04 |
Grünenthal GmbH |
Tamper resistant dosage form with bimodal release profile
|
|
MX371432B
(es)
|
2013-05-29 |
2020-01-30 |
Gruenenthal Gmbh |
Forma de dosificacion resistente al uso indebido que contiene una o mas particulas.
|
|
EP2808319A1
(en)
|
2013-05-31 |
2014-12-03 |
Arevipharma GmbH |
3-[3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex
|
|
US10624862B2
(en)
|
2013-07-12 |
2020-04-21 |
Grünenthal GmbH |
Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
|
|
WO2015071248A1
(en)
|
2013-11-15 |
2015-05-21 |
Synthon B.V. |
Abuse-proofed extended release pharmaceutical composition comprising tapentadol
|
|
WO2015078891A1
(en)
|
2013-11-26 |
2015-06-04 |
Farmaceutici Formenti S.P.A. |
Preparation of a powdery pharmaceutical composition by means of cryo-milling
|
|
AU2014365038B2
(en)
|
2013-12-16 |
2019-09-12 |
Grünenthal GmbH |
Tamper resistant dosage form with bimodal release profile manufactured by co-extrusion
|
|
US20150320690A1
(en)
|
2014-05-12 |
2015-11-12 |
Grünenthal GmbH |
Tamper resistant immediate release capsule formulation comprising tapentadol
|
|
EP3148512A1
(en)
|
2014-05-26 |
2017-04-05 |
Grünenthal GmbH |
Multiparticles safeguarded against ethanolic dose-dumping
|
|
EP3253376A1
(en)
|
2015-02-03 |
2017-12-13 |
Grünenthal GmbH |
Tamper-resistant dosage form comprising a polyethylene glycol graft copolymer
|
|
EA036258B1
(ru)
|
2015-03-27 |
2020-10-20 |
Грюненталь Гмбх |
Стабильный препарат для парентерального введения тапентадола
|
|
BR112017021475A2
(pt)
|
2015-04-24 |
2018-07-10 |
Gruenenthal Gmbh |
forma de dosagem resistente à adulteração (tamper) com liberação imediata e resistência contra extração de solvente
|
|
CA2983640A1
(en)
|
2015-04-24 |
2016-10-27 |
Grunenthal Gmbh |
Tamper-resistant fixed dose combination providing fast release of two drugs from different particles
|
|
BR112017022335A2
(pt)
|
2015-04-24 |
2018-07-10 |
Gruenenthal Gmbh |
combinação de dose fixa inviolável que fornece rápida liberação de dois fármacos a partir de partículas e matriz
|
|
JP2018515455A
(ja)
|
2015-04-24 |
2018-06-14 |
グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング |
粒子から2種の薬物の急速放出をもたらすタンパレジスタントな固定用量組合せ
|
|
AU2016319203A1
(en)
|
2015-09-10 |
2018-02-22 |
Grünenthal GmbH |
Protecting oral overdose with abuse deterrent immediate release formulations
|
|
PL3377049T3
(pl)
|
2015-11-17 |
2021-06-28 |
Msn Laboratories Private Limited |
Krystaliczne formy soli tapentadolu i sposób ich wytwarzania
|
|
KR20170003380U
(ko)
|
2016-03-21 |
2017-09-29 |
정화정 |
공기주입식 간판의 받침장치
|
|
US20170296476A1
(en)
|
2016-04-15 |
2017-10-19 |
Grünenthal GmbH |
Modified release abuse deterrent dosage forms
|
|
CA3029869A1
(en)
|
2016-07-06 |
2018-01-11 |
Grunenthal Gmbh |
Reinforced pharmaceutical dosage form
|
|
US20180028670A1
(en)
|
2016-08-01 |
2018-02-01 |
Grünenthal GmbH |
Tamper resistant dosage form comprising an anionic polysaccharide
|
|
JP2019524761A
(ja)
|
2016-08-12 |
2019-09-05 |
グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング |
エフェドリン及びその誘導体の改変防止製剤
|
|
CN109996533A
(zh)
|
2016-09-23 |
2019-07-09 |
格吕伦塔尔有限公司 |
用于肠胃外施用他喷他多的稳定制剂
|
|
EP3585370A1
(en)
|
2017-02-23 |
2020-01-01 |
Grünenthal GmbH |
Tapentadol as local anesthetic
|
|
MX2020003928A
(es)
|
2017-10-13 |
2020-10-14 |
Gruenenthal Gmbh |
Formas de dosificación de liberación modificada disuasivas del uso abusivo.
|
|
TW202002957A
(zh)
|
2018-02-09 |
2020-01-16 |
德商歌林達有限公司 |
包含轉化抑制劑之麻黃素及其衍生物之抗損壞調配物
|
|
EP3698776A1
(en)
|
2019-02-19 |
2020-08-26 |
Grünenthal GmbH |
Tamper-resistant dosage form with immediate release and resistance against solvent extraction
|
|
AU2020100442B4
(en)
*
|
2020-03-02 |
2020-06-18 |
Grünenthal GmbH |
Dosage form providing prolonged release of tapentadol phosphoric acid salt
|
|
EP3875079A1
(en)
|
2020-03-02 |
2021-09-08 |
Grünenthal GmbH |
Dosage form providing prolonged release of tapentadol phosphoric acid salt
|
|
AU2020100441B4
(en)
*
|
2020-03-02 |
2020-06-18 |
Grünenthal GmbH |
Dosage form providing prolonged release of tapentadol phosphoric acid salt
|
|
EP3875077B1
(en)
*
|
2020-03-02 |
2023-12-13 |
Grünenthal GmbH |
Dosage form providing prolonged release of tapentadol phosphoric acid salt
|
|
DE202021003994U1
(de)
|
2020-03-02 |
2022-04-12 |
Grünenthal GmbH |
Dosierungsform mit verlängerter Freisetzung von Tapentadol-Phosphorsäuresalz
|
|
WO2021219576A1
(en)
|
2020-04-27 |
2021-11-04 |
Grünenthal GmbH |
Multiparticulate dosage form containing eva copolymer and additional excipient
|
|
WO2021219577A1
(en)
|
2020-04-27 |
2021-11-04 |
Grünenthal GmbH |
Dosage form comprising hot-melt extruded pellets containing eva copolymer and gliding agent
|
|
DE202020104285U1
(de)
|
2020-07-24 |
2020-12-18 |
Grünenthal GmbH |
Ethylcellulose-beschichtete Partikel enthaltend ein Salz aus Tapentadol und Phosphorsäure
|
|
ES2927147T3
(es)
|
2020-11-10 |
2022-11-02 |
Gruenenthal Gmbh |
Forma de dosificación que proporciona liberación prolongada de una sal de Tapentadol con ácido L-(+)-tartárico
|
|
MX2023005472A
(es)
|
2020-11-10 |
2023-05-22 |
Gruenenthal Gmbh |
Formas de dosificacion de liberacion sostenida de una sal de tapentadol con acido l-(+)-tartarico.
|
|
DE202020005470U1
(de)
|
2020-11-10 |
2022-01-25 |
Grünenthal GmbH |
Darreichungsformen mit verlängerter Freisetzung eines Salzes von Tapentadol mit L-(+)-Weinsäure
|