PL1828125T3 - Pochodne arylopiperazyny i ich zastosowanie jako liganty selektywne receptora D3 dopaminy - Google Patents

Pochodne arylopiperazyny i ich zastosowanie jako liganty selektywne receptora D3 dopaminy

Info

Publication number
PL1828125T3
PL1828125T3 PL05822892T PL05822892T PL1828125T3 PL 1828125 T3 PL1828125 T3 PL 1828125T3 PL 05822892 T PL05822892 T PL 05822892T PL 05822892 T PL05822892 T PL 05822892T PL 1828125 T3 PL1828125 T3 PL 1828125T3
Authority
PL
Poland
Prior art keywords
nrr
alkylene
polyfluoro
alkyl
dopamine
Prior art date
Application number
PL05822892T
Other languages
English (en)
Inventor
Marc Capet
Denis Danvy
Catherine Dartois
Nicolas Levoin
Marcel Morvan
Isabelle Berrebi-Bertrand
Thierry Calmels
Philippe Robert
Jean-Charles Schwartz
Jeanne-Marie Lecomte
Original Assignee
Bioprojet Soc Civ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioprojet Soc Civ filed Critical Bioprojet Soc Civ
Publication of PL1828125T3 publication Critical patent/PL1828125T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL05822892T 2004-12-01 2005-11-29 Pochodne arylopiperazyny i ich zastosowanie jako liganty selektywne receptora D3 dopaminy PL1828125T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0412763A FR2878524B1 (fr) 2004-12-01 2004-12-01 Nouveaux derives d'arylpiperazine
EP05822892A EP1828125B1 (fr) 2004-12-01 2005-11-29 Derives d'arylpiperazine et leur utilisation comme ligands selectifs du recepteur d3 de la dopamine
PCT/FR2005/002964 WO2006058993A1 (fr) 2004-12-01 2005-11-29 Derives d’arylpiperazine et leur utilisation comme ligands selectifs du recepteur d3 de la dopamine

Publications (1)

Publication Number Publication Date
PL1828125T3 true PL1828125T3 (pl) 2008-09-30

Family

ID=34951009

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05822892T PL1828125T3 (pl) 2004-12-01 2005-11-29 Pochodne arylopiperazyny i ich zastosowanie jako liganty selektywne receptora D3 dopaminy

Country Status (12)

Country Link
US (1) US20080214542A1 (pl)
EP (1) EP1828125B1 (pl)
AT (1) ATE391711T1 (pl)
DE (1) DE602005006018T2 (pl)
DK (1) DK1828125T3 (pl)
ES (1) ES2302254T3 (pl)
FR (1) FR2878524B1 (pl)
HR (1) HRP20080187T3 (pl)
PL (1) PL1828125T3 (pl)
PT (1) PT1828125E (pl)
SI (1) SI1828125T1 (pl)
WO (1) WO2006058993A1 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006072608A2 (en) * 2005-01-03 2006-07-13 Universitá Degli Studi Di Siena Aryl piperazine derivatives for the treatment of neuropsychiatric disorders
EP1870405A1 (en) * 2006-06-22 2007-12-26 Bioprojet Carbonylated (Aza)cyclohexanes as dopamine D3 receptor ligands
WO2009095438A1 (en) * 2008-02-01 2009-08-06 Neurosearch A/S Novel aryl piperazine derivatives useful as modulators of dopamine and serotonin receptors
US20110085978A1 (en) * 2008-03-14 2011-04-14 Neurosearch A/S Novel quinolinylamide derivatives useful as modulators of dopamine and serotonin receptors
CN102264733B (zh) 2008-10-10 2014-07-30 中国人民解放军军事医学科学院毒物药物研究所 新型多巴胺d3受体配体，其制备方法及其医药用途
US9227944B2 (en) 2008-10-10 2016-01-05 Institute Of Pharmacology And Toxicology Academy Of Military Science P.L.A. China Dopamine D3 receptor ligands and preparation and medical uses of the same
WO2014079504A1 (en) * 2012-11-22 2014-05-30 Biofordrug S.R.L. Polycyclic ligands of 5-ht7 receptor and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0654023B1 (en) * 1992-08-06 1998-09-16 Smithkline Beecham Plc 5-(2-oxyphenyl)-pyrrole derivatives as dopamine d3 receptor antagonists
US5523229A (en) * 1994-03-22 1996-06-04 Trustees Of The University Of Pennsylvania Antibodies specific for oncofetal fibronectin
EP1464641B1 (en) * 1999-12-30 2008-05-14 H. Lundbeck A/S 4-Phenyl-piperazinyl, -piperidinyl and tetrahydropyridyl derivatives as dopamine D4 antagonists
MXPA04007920A (es) * 2002-02-13 2004-11-26 Glaxo Group Ltd Derivados de bencensulfonamida como agentes antisicoticos.
US20040204422A1 (en) * 2003-04-14 2004-10-14 Abbott Gmbh & Co. Kg. N-[(Piperazinyl)hetaryl]arylsulfonamide compounds

Also Published As

Publication number Publication date
EP1828125B1 (fr) 2008-04-09
EP1828125A1 (fr) 2007-09-05
ATE391711T1 (de) 2008-04-15
PT1828125E (pt) 2008-08-22
DE602005006018D1 (de) 2008-05-21
HRP20080187T3 (hr) 2008-05-31
DE602005006018T2 (de) 2008-07-10
FR2878524B1 (fr) 2007-01-19
US20080214542A1 (en) 2008-09-04
FR2878524A1 (fr) 2006-06-02
WO2006058993A1 (fr) 2006-06-08
DK1828125T3 (da) 2008-08-04
ES2302254T3 (es) 2008-07-01
SI1828125T1 (sl) 2008-08-31

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