PL1858916T3 - Warianty wirusa zapalenia wątroby typu b z obniżoną wrażliwością na analogi nukleozydów i ich zastosowanie - Google Patents

Warianty wirusa zapalenia wątroby typu b z obniżoną wrażliwością na analogi nukleozydów i ich zastosowanie

Info

Publication number
PL1858916T3
PL1858916T3 PL06723429T PL06723429T PL1858916T3 PL 1858916 T3 PL1858916 T3 PL 1858916T3 PL 06723429 T PL06723429 T PL 06723429T PL 06723429 T PL06723429 T PL 06723429T PL 1858916 T3 PL1858916 T3 PL 1858916T3
Authority
PL
Poland
Prior art keywords
hepatitis
nucleoside analogs
reduced susceptibility
viral variants
viral
Prior art date
Application number
PL06723429T
Other languages
English (en)
Other versions
PL1858916T4 (pl
Inventor
Mithat Bozdayi
Original Assignee
Fujirebio Europe N V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujirebio Europe N V filed Critical Fujirebio Europe N V
Publication of PL1858916T3 publication Critical patent/PL1858916T3/pl
Publication of PL1858916T4 publication Critical patent/PL1858916T4/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/706Specific hybridization probes for hepatitis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10121Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/106664Blood serum or blood plasma standard or control

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL06723429T 2005-03-15 2006-03-14 Warianty wirusa zapalenia wątroby typu b z obniżoną wrażliwością na analogi nukleozydów i ich zastosowanie PL1858916T4 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US66148405P 2005-03-15 2005-03-15
EP05101997 2005-03-15
EP06723429.4A EP1858916B1 (en) 2005-03-15 2006-03-14 Hepatitis-b viral variants with reduced susceptibility to nucleoside analogs and uses thereof
PCT/EP2006/002352 WO2006097285A1 (en) 2005-03-15 2006-03-14 Hepatitis-b viral variants with reduced susceptibility to nucleoside analogs and uses thereof

Publications (2)

Publication Number Publication Date
PL1858916T3 true PL1858916T3 (pl) 2015-01-30
PL1858916T4 PL1858916T4 (pl) 2015-04-30

Family

ID=35355552

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06723429T PL1858916T4 (pl) 2005-03-15 2006-03-14 Warianty wirusa zapalenia wątroby typu b z obniżoną wrażliwością na analogi nukleozydów i ich zastosowanie

Country Status (10)

Country Link
US (1) US7422848B2 (pl)
EP (1) EP1858916B1 (pl)
JP (1) JP2008537483A (pl)
CN (1) CN101203528A (pl)
AU (1) AU2006224789B2 (pl)
ES (1) ES2494840T3 (pl)
NZ (1) NZ562467A (pl)
PL (1) PL1858916T4 (pl)
PT (1) PT1858916E (pl)
WO (1) WO2006097285A1 (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE40233E1 (en) 1996-11-08 2008-04-08 Melbourne Health Viral variants and methods for detecting same
AUPO351996A0 (en) * 1996-11-08 1996-12-05 Western Health Care Network Viral variants and methods for detecting same
US7405039B2 (en) 2002-02-07 2008-07-29 Austin Health Viral variants with altered susceptibility to nucleoside analogs and uses thereof
TR200402517T1 (tr) * 2002-03-29 2007-12-24 Innogenetics N.V. HBV ilaç direnci tespit metotları
EP2033967A1 (en) 2002-04-12 2009-03-11 Melbourne Health Hepatitis B viral variants with reduced susceptibility to nucleoside analogs and uses thereof
PL1858916T4 (pl) 2005-03-15 2015-04-30 Fujirebio Europe N V Warianty wirusa zapalenia wątroby typu b z obniżoną wrażliwością na analogi nukleozydów i ich zastosowanie
WO2006097284A1 (en) * 2005-03-15 2006-09-21 Rheinische Friedrich-Wilhelms-Universität Bonn Variants of hepatitis b virus resistant against some nucleoside analogues, but sensitive to others, and uses thereof
JP2008534020A (ja) * 2005-04-08 2008-08-28 メルボルン ヘルス 抗ウイルス性のヌクレオシド剤に耐性を示すb型肝炎ウイルスのバリアントおよびその応用法
AU2006230802A1 (en) * 2005-04-08 2006-10-12 Austin Health Variants of hepatitis B virus with resistance to anti-viral nucleoside agents and applications thereof
KR101110013B1 (ko) * 2007-10-05 2012-02-29 (주)바이오니아 서열 내에 어베이직 부분을 포함하는 pcr 증폭용프라이머
JP2009213465A (ja) * 2007-10-30 2009-09-24 Toshiba Corp B型肝炎ウイルス薬剤耐性株検出用核酸プライマーセット、アッセイキットおよびb型肝炎ウィルスの薬剤耐性株の検出方法
CN106573960B (zh) * 2014-06-02 2021-07-02 Isa制药有限公司 用于针对乙型肝炎病毒感染的治疗性接种的合成长肽(slp)
US9963751B2 (en) 2015-11-24 2018-05-08 The Penn State Research Foundation Compositions and methods for identifying agents to reduce hepatitis B virus covalently closed circular DNA
WO2020117715A1 (en) 2018-12-03 2020-06-11 Board Of Regents, The University Of Texas System Oligo-benzamide analogs and their use in cancer treatment

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5576175A (en) 1989-09-20 1996-11-19 Immuno Aktiengesellschaft Complex suitable for carrying out a method of purifying pre-S hepatitis B surface antigen
US5849987A (en) 1992-06-02 1998-12-15 Yeda Research And Development Co. Ltd. Animal model for hepatitis virus infection
US5858328A (en) 1991-06-04 1999-01-12 Yeda Research And Development Co. Ltd. Animal model for hepatitis virus infection
CA2139735A1 (en) 1992-07-08 1994-01-20 Sing-Hiem Yap Polypeptides, derived from endonexin 2, having hepatitis b virus receptor activity and their use in diagnostic and pharmaceutical compositions
US5595739A (en) 1993-05-07 1997-01-21 Abbott Laboratories Hepatitis B virus mutants, reagents and methods for detection
US6242187B1 (en) 1996-01-29 2001-06-05 Virologic, Inc. Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening
US6100068A (en) 1997-01-21 2000-08-08 Paik-Inje Memorial Institute For Biomedical Science Method of protein production using mitochondrial translation system
US5817457A (en) 1996-02-07 1998-10-06 Ma Bioservices, Inc. Methods and kits for detecting viral reverse transcriptase activity in a sample using an acidic pH or an elevated temperature
US5877162A (en) 1996-03-14 1999-03-02 Innovir Laboratories, Inc. Short external guide sequences
ZA973367B (en) 1996-04-19 1997-11-18 Innogenetics Nv Method for typing and detecting HBV.
CA2252886C (en) 1996-04-26 2008-02-12 Massachusetts Institute Of Technology Three-hybrid screening assay
WO1998007869A1 (en) 1996-08-16 1998-02-26 Dong Wha Pharm. Ind. Co., Ltd. HBV POLYMERASE, RNase H ENZYME DERIVED FROM HBV POLYMERASE, PROCESSES FOR PREPARATION AND USES FOR SCREENING ANTIVIRAL AGENTS THEREOF
AUPO351996A0 (en) 1996-11-08 1996-12-05 Western Health Care Network Viral variants and methods for detecting same
US5939541A (en) 1997-03-28 1999-08-17 University Of South Carolina Method for enhancing expression of a foreign or endogenous gene product in plants
WO1999037821A1 (en) 1998-01-21 1999-07-29 The Penn State Research Foundation Methods and compositions to investigate infection by hepatitis b virus and agents to prevent and treat the infection
US6150105A (en) 1998-08-20 2000-11-21 Genetic Assays, Inc. Methods of screening nucleic acids for nucleotide variations
JP2000270876A (ja) 1999-03-26 2000-10-03 Genome Science Laboratories Co Ltd B型肝炎ウイルス遺伝子の変異検出方法および検出キット
AUPP967999A0 (en) 1999-04-09 1999-05-06 North Western Health Care Network Viral variants
ATE298004T1 (de) 1999-04-30 2005-07-15 Methexis Genomics N V Diagnostische sequenzierung durch eine kombination von spezifischer spaltung und massenspektrometrie
JP4502642B2 (ja) * 2002-02-07 2010-07-14 メルボルン ヘルス ヌクレオシドアナログに対する感受性の変化を有するウイルス変種およびその使用
TR200402517T1 (tr) 2002-03-29 2007-12-24 Innogenetics N.V. HBV ilaç direnci tespit metotları
EP2033967A1 (en) * 2002-04-12 2009-03-11 Melbourne Health Hepatitis B viral variants with reduced susceptibility to nucleoside analogs and uses thereof
US20040194155A1 (en) 2002-10-01 2004-09-30 Gilead Sciences, Inc. HBV mutations associated with reduced susceptibility to adefovir
PL1858916T4 (pl) 2005-03-15 2015-04-30 Fujirebio Europe N V Warianty wirusa zapalenia wątroby typu b z obniżoną wrażliwością na analogi nukleozydów i ich zastosowanie
WO2006097284A1 (en) 2005-03-15 2006-09-21 Rheinische Friedrich-Wilhelms-Universität Bonn Variants of hepatitis b virus resistant against some nucleoside analogues, but sensitive to others, and uses thereof

Also Published As

Publication number Publication date
PL1858916T4 (pl) 2015-04-30
US20060234212A1 (en) 2006-10-19
EP1858916A1 (en) 2007-11-28
WO2006097285A1 (en) 2006-09-21
NZ562467A (en) 2011-07-29
PT1858916E (pt) 2014-10-06
ES2494840T3 (es) 2014-09-16
AU2006224789B2 (en) 2012-09-06
AU2006224789A1 (en) 2006-09-21
US7422848B2 (en) 2008-09-09
CN101203528A (zh) 2008-06-18
JP2008537483A (ja) 2008-09-18
EP1858916B1 (en) 2014-07-09

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