PL186714B1 - Kompozycja farmaceutyczna do regulowania stężenialipidów do ssaka - Google Patents

Kompozycja farmaceutyczna do regulowania stężenialipidów do ssaka

Info

Publication number: PL186714B1
Authority: PL; Poland
Prior art keywords: phenyl; cholesterol; methylethyl; hmg; coa reductase
Prior art date: 1995-11-02

Application number

PL96326365A

Other languages

English (en)

Polish (pl)

Other versions

PL326365A1 (en

Inventor

Thomas M. A. Bocan

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-11-02

Filing date

1996-10-02

Publication date

2004-02-27

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21719566&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL186714(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-10-02 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

1998-09-14 Publication of PL326365A1 publication Critical patent/PL326365A1/xx

2004-02-27 Publication of PL186714B1 publication Critical patent/PL186714B1/pl

Links

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-1 2,6-bis(1-methylethyl)phenyl ester Chemical class 0.000 claims abstract description 29
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229920001277 pectin Polymers 0.000 description 1
239000000825 pharmaceutical preparation Substances 0.000 description 1
125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 description 1
NNQIBXKOCAMOOS-UHFFFAOYSA-N phenyl hypofluorite Chemical compound FOC1=CC=CC=C1 NNQIBXKOCAMOOS-UHFFFAOYSA-N 0.000 description 1
229940089484 pravachol Drugs 0.000 description 1
CQUXVIHRNRFVCJ-UHFFFAOYSA-N propan-2-yl N-phenylsulfamate Chemical compound CC(C)OS(=O)(=O)NC1=CC=CC=C1 CQUXVIHRNRFVCJ-UHFFFAOYSA-N 0.000 description 1
208000002815 pulmonary hypertension Diseases 0.000 description 1
238000011555 rabbit model Methods 0.000 description 1
230000009103 reabsorption Effects 0.000 description 1
230000001105 regulatory effect Effects 0.000 description 1
206010038464 renal hypertension Diseases 0.000 description 1
229920006395 saturated elastomer Polymers 0.000 description 1
208000007056 sickle cell anemia Diseases 0.000 description 1
239000007909 solid dosage form Substances 0.000 description 1
239000000243 solution Substances 0.000 description 1
239000002904 solvent Substances 0.000 description 1
239000003381 stabilizer Substances 0.000 description 1
239000008107 starch Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
239000000126 substance Substances 0.000 description 1
PCLPZFJBZOVJSU-UHFFFAOYSA-N sulfamoyl 2-[2,4,6-tri(propan-2-yl)phenyl]acetate Chemical compound CC(C)C1=CC(C(C)C)=C(CC(=O)OS(N)(=O)=O)C(C(C)C)=C1 PCLPZFJBZOVJSU-UHFFFAOYSA-N 0.000 description 1
229910052717 sulfur Inorganic materials 0.000 description 1
239000011593 sulfur Substances 0.000 description 1
239000000725 suspension Substances 0.000 description 1
239000000454 talc Substances 0.000 description 1
229910052623 talc Inorganic materials 0.000 description 1
235000012222 talc Nutrition 0.000 description 1
239000002562 thickening agent Substances 0.000 description 1
125000004014 thioethyl group Chemical group [H]SC([H])([H])C([H])([H])* 0.000 description 1
239000000196 tragacanth Substances 0.000 description 1
235000010487 tragacanth Nutrition 0.000 description 1
229940116362 tragacanth Drugs 0.000 description 1
201000010875 transient cerebral ischemia Diseases 0.000 description 1
230000024883 vasodilation Effects 0.000 description 1
239000011345 viscous material Substances 0.000 description 1
229940072168 zocor Drugs 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Emergency Medicine (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Obesity (AREA)
Endocrinology (AREA)
Hematology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

PL96326365A 1995-11-02 1996-10-02 Kompozycja farmaceutyczna do regulowania stężenialipidów do ssaka PL186714B1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US615595P	1995-11-02	1995-11-02
PCT/US1996/015854 WO1997016184A1 (en)	1995-11-02	1996-10-02	Method and pharmaceutical composition for regulating lipid concentration

Publications (2)

Publication Number	Publication Date
PL326365A1 PL326365A1 (en)	1998-09-14
PL186714B1 true PL186714B1 (pl)	2004-02-27

Family

ID=21719566

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL96326365A PL186714B1 (pl)	1995-11-02	1996-10-02	Kompozycja farmaceutyczna do regulowania stężenialipidów do ssaka

Country Status (26)

Country	Link
US (3)	US6124309A (2)
EP (1)	EP0858336B1 (2)
JP (1)	JPH11515025A (2)
KR (2)	KR100449604B1 (2)
CN (2)	CN1679953A (2)
AR (1)	AR004527A1 (2)
AT (1)	ATE348607T1 (2)
AU (1)	AU720853B2 (2)
BG (1)	BG64018B1 (2)
BR (1)	BR9611410A (2)
CZ (1)	CZ127198A3 (2)
DE (1)	DE69636783T2 (2)
EA (1)	EA000514B1 (2)
ES (1)	ES2279526T3 (2)
GE (1)	GEP20001898B (2)
HU (1)	HUP9901865A3 (2)
IL (1)	IL123902A (2)
IS (1)	IS4720A (2)
NO (1)	NO981961L (2)
NZ (2)	NZ512484A (2)
PL (1)	PL186714B1 (2)
RO (1)	RO120816B1 (2)
SK (1)	SK284142B6 (2)
UA (1)	UA46069C2 (2)
WO (1)	WO1997016184A1 (2)
ZA (1)	ZA969187B (2)

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1996
- 1996-10-02 AU AU72539/96A patent/AU720853B2/en not_active Ceased
- 1996-10-02 GE GEAP19964269A patent/GEP20001898B/en unknown
- 1996-10-02 ES ES96934020T patent/ES2279526T3/es not_active Expired - Lifetime
- 1996-10-02 CZ CZ981271A patent/CZ127198A3/cs unknown
- 1996-10-02 US US09/051,368 patent/US6124309A/en not_active Expired - Fee Related
- 1996-10-02 CN CNA2005100517235A patent/CN1679953A/zh active Pending
- 1996-10-02 HU HU9901865A patent/HUP9901865A3/hu unknown
- 1996-10-02 JP JP9517342A patent/JPH11515025A/ja not_active Ceased
- 1996-10-02 BR BR9611410A patent/BR9611410A/pt not_active Application Discontinuation
- 1996-10-02 UA UA98052811A patent/UA46069C2/uk unknown
- 1996-10-02 EP EP96934020A patent/EP0858336B1/en not_active Revoked
- 1996-10-02 NZ NZ512484A patent/NZ512484A/xx unknown
- 1996-10-02 KR KR10-1998-0703240A patent/KR100449604B1/ko not_active Expired - Fee Related
- 1996-10-02 CN CN961980109A patent/CN1217656C/zh not_active Expired - Fee Related
- 1996-10-02 EA EA199800420A patent/EA000514B1/ru not_active IP Right Cessation
- 1996-10-02 NZ NZ319906A patent/NZ319906A/en unknown
- 1996-10-02 AT AT96934020T patent/ATE348607T1/de not_active IP Right Cessation
- 1996-10-02 DE DE69636783T patent/DE69636783T2/de not_active Expired - Fee Related
- 1996-10-02 KR KR10-2004-7003107A patent/KR20040029459A/ko not_active Ceased
- 1996-10-02 WO PCT/US1996/015854 patent/WO1997016184A1/en not_active Ceased
- 1996-10-02 IL IL12390296A patent/IL123902A/xx not_active IP Right Cessation
- 1996-10-02 PL PL96326365A patent/PL186714B1/pl not_active IP Right Cessation
- 1996-10-02 SK SK557-98A patent/SK284142B6/sk unknown
- 1996-10-02 RO RO98-00919A patent/RO120816B1/ro unknown
- 1996-10-31 ZA ZA969187A patent/ZA969187B/xx unknown
- 1996-11-01 AR ARP960105005A patent/AR004527A1/es unknown
1998
- 1998-04-17 IS IS4720A patent/IS4720A/is unknown
- 1998-04-29 BG BG102417A patent/BG64018B1/bg unknown
- 1998-04-30 NO NO981961A patent/NO981961L/no unknown
1999
- 1999-07-01 US US09/345,944 patent/US6093719A/en not_active Expired - Fee Related
- 1999-07-01 US US09/346,503 patent/US6143755A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US6093719A (en)	2000-07-25
BG102417A (en)	1999-01-29
US6143755A (en)	2000-11-07
GEP20001898B (en)	2000-01-05
BR9611410A (pt)	1999-01-05
ATE348607T1 (de)	2007-01-15
NO981961D0 (no)	1998-04-30
NO981961L (no)	1998-05-04
AU7253996A (en)	1997-05-22
BG64018B1 (bg)	2003-10-31
PL326365A1 (en)	1998-09-14
CN1201389A (zh)	1998-12-09
EA199800420A1 (ru)	1998-10-29
IS4720A (is)	1998-04-17
ES2279526T3 (es)	2007-08-16
NZ319906A (en)	2000-02-28
HUP9901865A3 (en)	2000-06-28
ZA969187B (en)	1997-05-29
SK284142B6 (sk)	2004-10-05
IL123902A0 (en)	1998-10-30
HUP9901865A2 (hu)	1999-10-28
AU720853B2 (en)	2000-06-15
EA000514B1 (ru)	1999-10-28
DE69636783D1 (de)	2007-02-01
JPH11515025A (ja)	1999-12-21
DE69636783T2 (de)	2007-10-18
CN1217656C (zh)	2005-09-07
KR100449604B1 (ko)	2004-11-16
CZ127198A3 (cs)	1998-12-16
UA46069C2 (uk)	2002-05-15
RO120816B1 (ro)	2006-08-30
KR20040029459A (ko)	2004-04-06
KR19990067270A (ko)	1999-08-16
NZ512484A (en)	2003-02-28
US6124309A (en)	2000-09-26
SK55798A3 (en)	1999-06-11
AR004527A1 (es)	1998-12-16
WO1997016184A1 (en)	1997-05-09
IL123902A (en)	2003-01-12
EP0858336A1 (en)	1998-08-19
HK1016509A1 (en)	1999-11-05
CN1679953A (zh)	2005-10-12
EP0858336B1 (en)	2006-12-20

Legal Events

Date	Code	Title	Description
2008-03-31	LAPS	Decisions on the lapse of the protection rights	Effective date: 20061002

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EA002435B1 (ru)	2002-04-25	Способ снижения уровня липопротеина (а) в сыворотке или в плазме крови млекопитающих
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EA016855B1 (ru)	2012-08-30	Применение l-карнитина и/или алканоил l-карнитина в комбинации со статином для лечения диабета 2 типа
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US20050234124A1 (en)	2005-10-20	Carboxyalkylether-ACAT inhibitor combinations
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