PL187010B1 - Pesticide - Google Patents

Abstract

A pesticide containing known auxiliary substances, characterized in that it contains as a biologically active substance a mixture consisting of: 1.00-98.999% by weight of 2-isopropoxyphenyl-N-methylcarbamate (propoxur), 0.001-25% by weight of (1RS,3RS)-3-(2,2-dichlorovinyl)-2,2-dimethylcycloprop;mox;carboxylate (S,R)-ca-cyano-3-phenoxybenzyl (alpha-cypermethrin) and 0-3,5,6-trichloropyridin-2-yl-0,0-diethyl thiophosphate (chlorpyrifos) in an amount of 1.00-98.999% by weight.

Description

The subject of the invention is a broad-spectrum pesticidal agent.

There are known insecticides used to control pests, such as pyrethroids, e.g. alphacypermethrin (previously named alphamethrin) [(S,R)-α-cyano-3-phenoxybenzyl (1RS,3RS)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate], carbamates, e.g. propoxur [2-isopropoxy-phenyl-N-methyl-carbamate], organophosphorus compounds, e.g. chlorpyrifos [0-3,5,6-trichloropyridin-2-yl-0,0-diethyl thiophosphate].

The disadvantage of these agents is the short-term effect, e.g. propoxur, or the rapid development of pest resistance, as well as poor effect at high temperatures, e.g. alphacypermethrin, or the need to use high doses, e.g. chlorpyrifos.

Mixtures of methoxychlor, propoxur, and alphacypermethrin, as well as propoxur with alphacypermethrin, which mitigate these drawbacks, are also known from Polish patents Nos. 168,586 and 170,244. These mixtures are used to control troublesome insects in sanitary hygiene. Methoxychlor, both in mixtures and in single-component preparations, has been used for over 30 years and, as a chlorinated hydrocarbon, is gradually being phased out for toxicological reasons.

Unexpectedly, a preparation containing propoxur, alphacypermethrin, and the organophosphate chlorpyrifos was found to have a synergistic effect, allowing for a significant reduction in the effective dose. The preparation demonstrates a broad spectrum of insecticidal activity, also enabling the control of pests resistant to chlorinated hydrocarbons and pyrethroids, and delays the development of resistance to the insecticides contained in the mixture.

The subject of the invention is an insecticide containing as a biologically active substance a mixture of 1.00-98.999% by weight of propoxur and 0.001-25% by weight of alphacypermethrin with 1.00-98.999% by weight of chlorpyrifos.

In addition to biologically active substances, the composition of the agent according to the invention includes carriers, solvents, and other substances such as emulsifiers, dispersants, wetting agents, adhesives, antifoaming agents, decomposition inhibitors of biologically active substances, other stabilizers, dyes, and fragrances. Organic liquids such as aromatic and aliphatic hydrocarbons, aliphatic or cyclic ketones, esters, alcohols, and glycols are used as solvents. Natural or synthetic mineral substances such as kaolin, talc, phyllite flour, and silicas are used as carriers. Salts of lignin sulfonic acids, alkylbenzenesulfonic acids, nonionic adducts of alkylene oxides and alkylphenols or fatty alcohols, copolymers of alkylene oxides, sorbitol esters and fatty acids, as well as N-methyltaurine derivatives, salts of naphthalenesulfonic acids and alkyl sulfates are used as surfactants.

The agent according to the invention can be used to protect plants and premises from harmful insects. In sanitary hygiene, it combats flies, mosquitoes, cockroaches, and ants.

187 010 for pharaoh ants, bedbugs, fleas, and other arthropods. Outdoors, it can be used to control ants and wood-destroying pests.

The selection of the mixture components, in addition to synergism, has a relatively long-lasting effect, allowing the control of newly hatched larvae or caterpillars both at high temperatures, e.g. 35°C, and at low temperatures, e.g. 15°C, and slows down the development of insect resistance.

The insecticidal action of the agent according to the invention is illustrated by Example I, and the production method by Examples II, III and IV.

Example I

The inventive agent, dissolved in acetone, was applied by individual dosing (1 µl/individual) to the Oriental cockroach (Blatta orientalis L.) and housefly (Musca domestica L.), using 8-10 concentrations of the mixture or single-component formulations. Each concentration was tested on 30-45 insects. Mortality rates were determined after 24 hours of the experiment. The dose causing 50% mortality (LD50) was calculated using the log-probit method. The insecticidal efficacy results of the inventive agent compared to the individual biologically active ingredients are presented in Tables 1 and 2.

The proportion of active substances constituting the LD50 was lower compared to the individual substances; in the case of the eastern cockroach, for chlorpyrifos, approximately 30 times, propoxur, approximately 5 times, and alpha-cypermethrin, 7 times. For the housefly, these indicators were lower for chlorpyrifos, 19 times, propoxur, 130 times, and alpha-cypermethrin, 2.5 times, respectively.

Example II

The agent in the form of an emulsifying solution (EC) is obtained by dissolving 12 parts by weight of propoxur, 7 parts by weight of chlorpyrifos and 1.3 parts by weight of alpha-cypermethiine and 10 parts by weight of an emulsifier being a mixture of polyoxyethylene castor oil and calcium salt of dodecylbenzenesulfonic acid and isobutyl alcohol in 5.7 parts of acetophenone and 64 parts of a mixture of aromatic hydrocarbons known under the trade name Solvesso 100.

Example III

The aerosol diffuser is obtained by dissolving 2 parts by weight of chlorpyrifos, 1 part by weight of propoxur and 0.1 part by weight of alphacypermethrin in a mixture of 3 parts by weight of ethyl acetate, 93 parts by weight of isopropanol and 0.9 parts by weight of polyethylene glycol with a molecular weight of 300, then introducing the obtained solution into aerosol containers in the amount of 100 g per container, closing it with an aerosol valve and topping up with a carrier gas, the so-called propellant, which may be, for example, a mixture of propane and butane known as Drivosol in the amount of 80 g per container.

Example IV . . .

The agent in the form of a wettable powder (WP) is obtained by mixing 9 parts by weight of chlorpyrifos, 2 parts by weight of alphacypermethrin and 18 parts by weight of propoxur, and 8 parts by weight of the sum of the surfactant components of sodium lignin sulfonates (Borrespersa Na), formaldehyde condensation products of betanaphthalenesulfonic acid (Dyspergator NNO) and non-ionic adducts of ethylene oxide and alkylphenols (Rokafenol N-8) together with 63 parts of a mixture of carriers consisting of synthetic silica and kaolin used in a ratio of 1:3. The whole is ground in a jet mill.

187 010

Table 1

Insecticidal efficacy of the agent according to the invention in comparison with the known mixture and the single components in relation to the oriental cockroach (Blatta orientalis L.)

Content of biologically active substances in % by weight LD50 pg/individual Contribution of biologically active substances to LD50 chlorpyrifos propoxure alphacypermethrin The agent according to the invention, proportions as in Example II: chlorpyrifos - 35% propoxur - 59% alphacypermethrin - 6% 0.00781 0.00273 0.00461 0.00047 Known mixture: propoxur - 96% alphacypermethrin - 6% 0.01481 0.01420 0.00061 Known individual ingredients: chlorpyrifos 100% propoxur 100% alphacypermethrin 100% 0.08205 0.02259 0.00334 0.08205 0.02259 0.00334

Table 2

Insecticidal efficacy of the agent according to the invention in comparison with the known mixture and the individual components in relation to the housefly (Musca domestica L.)

Content of biologically active substances in % by weight LD50 pg/individual Contribution of biologically active substances to LD50 chlorpyrifos propoxure alphacypermethrin Inventive agent: proportion as in Example II: chlorpyrifos - 35% propoxur - 59% alphacypermethrin - 6% 0.00949 0.00332 0.00560 0.00057 Known mixture: propoxur - 96% alphacypermethrin - 6% 0.03077 0.02949 0.00128 Known single ingredients: chlorpyrifos 1 (00% propoxur 1 (00% alphacypermethrin 100% 0.06406 0.7295 0.00146 0.06406 0.7295 0.00146

Publishing Department of the Polish Patent Office. Circulation: 50 copies. Price: PLN 2.00.

Claims (1)

Patent claim Pesticide containing known auxiliary substances, characterized in that the biologically active substance is a mixture consisting of: 1.00-98.999% by weight 2-isopropoxy-phenyl-N-methyl-carbamate (propoxur), 0.001-25% by weight (1RS , 3RS) -3- (2,2-dichlorovinyl) -2,2-dimethylcyclopropanecarboxylate (S, R) -a-cyano-3-phenoxybenzyl (alphacypermethrin) and 0-3,5,6-trichloropyridin-2-yl thiophosphate -0,0-diethyl (chlorpyrifos) in an amount of 1.00-98.999% by weight.