PL1874761T3 - Pochodne 4H-1,2,4-triazyn-5-onu, ich wytwarzanie i ich zastosowanie jako receptorów nikotynowych acetylocholiny typu a7 - Google Patents
Pochodne 4H-1,2,4-triazyn-5-onu, ich wytwarzanie i ich zastosowanie jako receptorów nikotynowych acetylocholiny typu a7Info
- Publication number
- PL1874761T3 PL1874761T3 PL06755440T PL06755440T PL1874761T3 PL 1874761 T3 PL1874761 T3 PL 1874761T3 PL 06755440 T PL06755440 T PL 06755440T PL 06755440 T PL06755440 T PL 06755440T PL 1874761 T3 PL1874761 T3 PL 1874761T3
- Authority
- PL
- Poland
- Prior art keywords
- triazin
- alpha
- derivatives
- preparation
- nicotinic acetylcholine
- Prior art date
Links
- BFNNILAMSKQDRN-UHFFFAOYSA-N 2h-1,2,4-triazin-5-one Chemical class O=C1C=NNC=N1 BFNNILAMSKQDRN-UHFFFAOYSA-N 0.000 title 1
- 102000047725 alpha7 Nicotinic Acetylcholine Receptor Human genes 0.000 title 1
- 108700006085 alpha7 Nicotinic Acetylcholine Receptor Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0504042A FR2884822B1 (fr) | 2005-04-22 | 2005-04-22 | Derives de triazines, leur preparation et leur application en therapeutique |
| EP06755440A EP1874761B1 (fr) | 2005-04-22 | 2006-04-21 | Derives de 4h-1,2,4-triazin-5-0nes, leur preparation et leur utilisation comme des recepteurs a l'acetylcholine de type nicotiniques alpha7 |
| PCT/FR2006/000887 WO2006111662A2 (fr) | 2005-04-22 | 2006-04-21 | Derives de 4h-1 , 2 , 4-triazin-5-0nes , leur preparation et leur utilisation comme des recepteurs a l'acetylcholine de type nicotiniques alpha7 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1874761T3 true PL1874761T3 (pl) | 2011-02-28 |
Family
ID=35219499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06755440T PL1874761T3 (pl) | 2005-04-22 | 2006-04-21 | Pochodne 4H-1,2,4-triazyn-5-onu, ich wytwarzanie i ich zastosowanie jako receptorów nikotynowych acetylocholiny typu a7 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7517881B2 (pl) |
| EP (1) | EP1874761B1 (pl) |
| JP (1) | JP4966295B2 (pl) |
| AR (1) | AR054033A1 (pl) |
| AT (1) | ATE478068T1 (pl) |
| CY (1) | CY1111288T1 (pl) |
| DE (1) | DE602006016258D1 (pl) |
| DK (1) | DK1874761T3 (pl) |
| ES (1) | ES2350950T3 (pl) |
| FR (1) | FR2884822B1 (pl) |
| HR (1) | HRP20100604T1 (pl) |
| PL (1) | PL1874761T3 (pl) |
| PT (1) | PT1874761E (pl) |
| RS (1) | RS51557B (pl) |
| SI (1) | SI1874761T1 (pl) |
| TW (1) | TW200708506A (pl) |
| WO (1) | WO2006111662A2 (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0220581D0 (en) | 2002-09-04 | 2002-10-09 | Novartis Ag | Organic Compound |
| AR049401A1 (es) | 2004-06-18 | 2006-07-26 | Novartis Ag | Aza-biciclononanos |
| GB0415746D0 (en) | 2004-07-14 | 2004-08-18 | Novartis Ag | Organic compounds |
| GB0521508D0 (en) | 2005-10-21 | 2005-11-30 | Novartis Ag | Organic compounds |
| GB0525673D0 (en) | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
| GB0525672D0 (en) | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
| JO3250B1 (ar) | 2009-09-22 | 2018-09-16 | Novartis Ag | إستعمال منشطات مستقبل نيكوتينيك أسيتيل كولين ألفا 7 |
| EP3455223B1 (en) * | 2016-05-12 | 2023-11-08 | Buck Institute for Research on Aging | Compounds to promote normal processing of app |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4774604B2 (ja) * | 2000-02-14 | 2011-09-14 | 和光純薬工業株式会社 | 第４級アンモニウム塩の製造方法 |
| JP4616971B2 (ja) * | 2000-07-18 | 2011-01-19 | 田辺三菱製薬株式会社 | １−アザビシクロアルカン化合物およびその医薬用途 |
| CA2462453C (en) * | 2001-10-02 | 2009-07-28 | Pharmacia & Upjohn Company | Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease |
| SE0301320D0 (sv) * | 2003-05-06 | 2003-05-06 | Astrazeneca Ab | Positive modulators of nicotinic acetylcholine receptors |
-
2005
- 2005-04-22 FR FR0504042A patent/FR2884822B1/fr not_active Expired - Fee Related
-
2006
- 2006-04-20 AR ARP060101561A patent/AR054033A1/es unknown
- 2006-04-21 RS RSP-2010/0487A patent/RS51557B/sr unknown
- 2006-04-21 JP JP2008507128A patent/JP4966295B2/ja not_active Expired - Fee Related
- 2006-04-21 SI SI200630825T patent/SI1874761T1/sl unknown
- 2006-04-21 AT AT06755440T patent/ATE478068T1/de active
- 2006-04-21 PT PT06755440T patent/PT1874761E/pt unknown
- 2006-04-21 DE DE602006016258T patent/DE602006016258D1/de not_active Expired - Lifetime
- 2006-04-21 DK DK06755440.2T patent/DK1874761T3/da active
- 2006-04-21 PL PL06755440T patent/PL1874761T3/pl unknown
- 2006-04-21 WO PCT/FR2006/000887 patent/WO2006111662A2/fr not_active Ceased
- 2006-04-21 HR HR20100604T patent/HRP20100604T1/hr unknown
- 2006-04-21 ES ES06755440T patent/ES2350950T3/es not_active Expired - Lifetime
- 2006-04-21 EP EP06755440A patent/EP1874761B1/fr not_active Expired - Lifetime
- 2006-04-21 TW TW095114225A patent/TW200708506A/zh unknown
-
2007
- 2007-10-09 US US11/869,260 patent/US7517881B2/en not_active Expired - Fee Related
-
2010
- 2010-11-12 CY CY20101101023T patent/CY1111288T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1874761A2 (fr) | 2008-01-09 |
| ATE478068T1 (de) | 2010-09-15 |
| DE602006016258D1 (de) | 2010-09-30 |
| DK1874761T3 (da) | 2010-12-13 |
| HRP20100604T1 (hr) | 2010-12-31 |
| PT1874761E (pt) | 2010-11-18 |
| JP4966295B2 (ja) | 2012-07-04 |
| CY1111288T1 (el) | 2015-08-05 |
| SI1874761T1 (sl) | 2010-12-31 |
| WO2006111662A2 (fr) | 2006-10-26 |
| FR2884822B1 (fr) | 2007-06-29 |
| US7517881B2 (en) | 2009-04-14 |
| JP2008536902A (ja) | 2008-09-11 |
| TW200708506A (en) | 2007-03-01 |
| FR2884822A1 (fr) | 2006-10-27 |
| WO2006111662A3 (fr) | 2006-11-30 |
| US20080096891A1 (en) | 2008-04-24 |
| EP1874761B1 (fr) | 2010-08-18 |
| RS51557B (sr) | 2011-06-30 |
| AR054033A1 (es) | 2007-05-30 |
| ES2350950T3 (es) | 2011-01-28 |
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