PL1888077T3 - Kompozycja farmaceutyczna zawierająca gestageny, i/lub estrogeny i 5-metylo-(6S)-tetrahydrofolian - Google Patents

Kompozycja farmaceutyczna zawierająca gestageny, i/lub estrogeny i 5-metylo-(6S)-tetrahydrofolian

Info

Publication number
PL1888077T3
PL1888077T3 PL06753787T PL06753787T PL1888077T3 PL 1888077 T3 PL1888077 T3 PL 1888077T3 PL 06753787 T PL06753787 T PL 06753787T PL 06753787 T PL06753787 T PL 06753787T PL 1888077 T3 PL1888077 T3 PL 1888077T3
Authority
PL
Poland
Prior art keywords
tetrahydrofolate
estrogens
methyl
pharmaceutical composition
composition containing
Prior art date
Application number
PL06753787T
Other languages
English (en)
Inventor
Kai Strothmann
Gavin Welch Smith
Kristina King
Rudolf Moser
Klaus Pietrzik
Original Assignee
Merck&Cie
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37396913&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1888077(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE102005023301A external-priority patent/DE102005023301B4/de
Priority claimed from DE102006016285A external-priority patent/DE102006016285A1/de
Application filed by Merck&Cie, Bayer Ip Gmbh filed Critical Merck&Cie
Publication of PL1888077T3 publication Critical patent/PL1888077T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415Pyridoxine, i.e. Vitamin B6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525Isoalloxazines, e.g. riboflavins, vitamin B2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06Antiabortive agents; Labour repressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34Gestagens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
PL06753787T 2005-05-13 2006-05-15 Kompozycja farmaceutyczna zawierająca gestageny, i/lub estrogeny i 5-metylo-(6S)-tetrahydrofolian PL1888077T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE102005023301A DE102005023301B4 (de) 2005-05-13 2005-05-13 Pharmazeutische Zusammensetzung enthaltend Gestagene und/oder Estrogene und 5-Methyl-(6S)-tetrahydrofolat
DE102006016285A DE102006016285A1 (de) 2006-04-03 2006-04-03 Pharmazeutische Zusammensetzung enthaltend Gestagene und/oder Estrogene und 5-Methyl-(6S)-tetrahydrofolat
EP06753787A EP1888077B1 (de) 2005-05-13 2006-05-15 Pharmazeutische zusammensetzung enthaltend gestagene und/oder estrogene und 5-methyl-(6s)-tetrahydrofolat
PCT/EP2006/004858 WO2006120035A2 (de) 2005-05-13 2006-05-15 Pharmazeutische zusammensetzung enthaltend gestagene und/oder estrogene und 5-methyl-(6s)-tetrahydrofolat

Publications (1)

Publication Number Publication Date
PL1888077T3 true PL1888077T3 (pl) 2009-12-31

Family

ID=37396913

Family Applications (2)

Application Number Title Priority Date Filing Date
PL06753787T PL1888077T3 (pl) 2005-05-13 2006-05-15 Kompozycja farmaceutyczna zawierająca gestageny, i/lub estrogeny i 5-metylo-(6S)-tetrahydrofolian
PL09075120T PL2116249T3 (pl) 2005-05-13 2006-05-15 Kompozycja farmaceutyczna zawierająca gestageny, i/lub estrogeny i 5-metylo-(6S)-tetrahydrofolian

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL09075120T PL2116249T3 (pl) 2005-05-13 2006-05-15 Kompozycja farmaceutyczna zawierająca gestageny, i/lub estrogeny i 5-metylo-(6S)-tetrahydrofolian

Country Status (37)

Country Link
US (2) US20080160004A1 (pl)
EP (3) EP2116249B2 (pl)
JP (2) JP2008540482A (pl)
KR (2) KR20080028369A (pl)
CN (2) CN101954083A (pl)
AR (1) AR054123A1 (pl)
AT (2) ATE429917T1 (pl)
AU (1) AU2006245921A1 (pl)
BR (1) BRPI0611443B8 (pl)
CA (1) CA2608639C (pl)
CL (2) CL2009002187A1 (pl)
CR (1) CR9531A (pl)
CY (2) CY1109261T1 (pl)
DE (1) DE502006003617D1 (pl)
DK (2) DK1888077T3 (pl)
DO (1) DOP2006000110A (pl)
EA (2) EA028530B1 (pl)
EC (1) ECSP078001A (pl)
ES (2) ES2325600T3 (pl)
GT (1) GT200600200A (pl)
HR (1) HRP20090418T1 (pl)
IL (1) IL187340A (pl)
MA (1) MA29448B1 (pl)
MY (1) MY147362A (pl)
NO (1) NO345807B1 (pl)
PE (1) PE20061415A1 (pl)
PL (2) PL1888077T3 (pl)
PT (2) PT2116249E (pl)
RS (2) RS52651B (pl)
SG (1) SG169973A1 (pl)
SI (2) SI1888077T1 (pl)
SV (1) SV2008002527A (pl)
TN (1) TNSN07418A1 (pl)
TW (1) TWI380820B (pl)
UY (1) UY29527A1 (pl)
WO (1) WO2006120035A2 (pl)
ZA (2) ZA200710811B (pl)

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HUE054589T2 (hu) 2015-06-18 2021-09-28 Estetra Sprl Szájban diszpergálódó esztetrol tartalmú tabletta
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CN106336444A (zh) * 2016-08-23 2017-01-18 国家卫生计生委科学技术研究所 一种新晶型炔雌醇
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
DK3781171T3 (da) 2018-04-19 2022-05-02 Estetra Srl Sammensætninger og deres anvendelser til lindring af menopause-associerede symptomer
TWI893101B (zh) 2020-04-16 2025-08-11 比利時商埃斯特拉有限責任公司 具有降低之副作用之避孕組成物

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Also Published As

Publication number Publication date
CR9531A (es) 2008-02-21
EA200901393A1 (ru) 2010-02-26
AR054123A1 (es) 2007-06-06
DK2116249T3 (da) 2012-08-20
NO345807B1 (no) 2021-08-16
RS52651B (sr) 2013-06-28
SI2116249T1 (sl) 2013-02-28
IL187340A (en) 2015-03-31
SG169973A1 (en) 2011-04-29
ATE555791T1 (de) 2012-05-15
HRP20090418T1 (hr) 2009-09-30
BRPI0611443B8 (pt) 2021-05-25
EP2116249B1 (de) 2012-05-02
US20160095860A1 (en) 2016-04-07
ES2387525T3 (es) 2012-09-25
SV2008002527A (es) 2008-03-27
JP2008540482A (ja) 2008-11-20
ES2387525T5 (es) 2024-07-05
UY29527A1 (es) 2006-12-29
AU2006245921A1 (en) 2006-11-16
EP2116249B2 (de) 2023-04-05
CY1114403T1 (el) 2016-08-31
EA014664B1 (ru) 2010-12-30
PT1888077E (pt) 2009-07-20
CL2009002187A1 (es) 2010-10-01
KR101598735B1 (ko) 2016-03-02
CL2010000989A1 (es) 2011-02-18
DOP2006000110A (es) 2012-06-15
DE502006003617D1 (de) 2009-06-10
DK1888077T3 (da) 2009-08-17
ECSP078001A (es) 2008-01-23
ATE429917T1 (de) 2009-05-15
CA2608639A1 (en) 2006-11-16
TWI380820B (zh) 2013-01-01
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EP2116249A1 (de) 2009-11-11
EA028530B1 (ru) 2017-11-30
PL2116249T3 (pl) 2013-06-28
CA2608639C (en) 2013-04-30
IL187340A0 (en) 2011-08-01
MA29448B1 (fr) 2008-05-02
CN101198332A (zh) 2008-06-11
CN101954083A (zh) 2011-01-26
ES2325600T3 (es) 2009-09-09
WO2006120035A2 (de) 2006-11-16
TNSN07418A1 (en) 2009-03-17
US20080160004A1 (en) 2008-07-03
BRPI0611443B1 (pt) 2020-07-21
HK1118729A1 (en) 2009-02-20
US10463666B2 (en) 2019-11-05
JP2013166753A (ja) 2013-08-29
EP2298307A1 (de) 2011-03-23
JP5883810B2 (ja) 2016-03-15
EP1888077B1 (de) 2009-04-29
PT2116249E (pt) 2012-08-07
ZA200908894B (en) 2025-01-29
GT200600200A (es) 2007-03-23
CY1109261T1 (el) 2014-07-02
WO2006120035A3 (de) 2007-02-15
BRPI0611443A2 (pt) 2010-09-08
SI1888077T1 (sl) 2009-10-31
KR20140069175A (ko) 2014-06-09
RS50972B (sr) 2010-10-31
ZA200710811B (en) 2012-06-27
MY147362A (en) 2012-11-30
KR20080028369A (ko) 2008-03-31
EA200702349A1 (ru) 2008-04-28
NO20076408L (no) 2008-02-12
EP1888077A2 (de) 2008-02-20
CN101198332B (zh) 2012-07-18
PE20061415A1 (es) 2007-01-26

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