PL1910398T3 - 17-alfa-podstawione pochodne estradiolu wykazujące działanie gojenia ran - Google Patents
17-alfa-podstawione pochodne estradiolu wykazujące działanie gojenia ranInfo
- Publication number
- PL1910398T3 PL1910398T3 PL06762874T PL06762874T PL1910398T3 PL 1910398 T3 PL1910398 T3 PL 1910398T3 PL 06762874 T PL06762874 T PL 06762874T PL 06762874 T PL06762874 T PL 06762874T PL 1910398 T3 PL1910398 T3 PL 1910398T3
- Authority
- PL
- Poland
- Prior art keywords
- estradiol
- alpha
- wound
- substituted derivatives
- healing activity
- Prior art date
Links
- 230000000694 effects Effects 0.000 title abstract 2
- 150000002159 estradiols Chemical class 0.000 title 1
- 230000029663 wound healing Effects 0.000 title 1
- DNXHEGUUPJUMQT-UHFFFAOYSA-N (+)-estrone Natural products OC1=CC=C2C3CCC(C)(C(CC4)=O)C4C3CCC2=C1 DNXHEGUUPJUMQT-UHFFFAOYSA-N 0.000 abstract 1
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 abstract 1
- DNXHEGUUPJUMQT-CBZIJGRNSA-N Estrone Chemical compound OC1=CC=C2[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 DNXHEGUUPJUMQT-CBZIJGRNSA-N 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229960005309 estradiol Drugs 0.000 abstract 1
- 229930182833 estradiol Natural products 0.000 abstract 1
- 229960003399 estrone Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0085—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0096—Alkynyl derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001516A ITMI20051516A1 (it) | 2005-08-02 | 2005-08-02 | Derivati 17 alfa-sostituti dell'estradiolo ad attivita' cicatrizzante |
| PCT/EP2006/007488 WO2007014711A1 (en) | 2005-08-02 | 2006-07-28 | 17-alpha-substituted derivatives of estradiol with wound-healing activity |
| EP06762874A EP1910398B1 (en) | 2005-08-02 | 2006-07-28 | 17-alpha-substituted derivatives of estradiol with wound-healing activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1910398T3 true PL1910398T3 (pl) | 2011-05-31 |
Family
ID=37564355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06762874T PL1910398T3 (pl) | 2005-08-02 | 2006-07-28 | 17-alfa-podstawione pochodne estradiolu wykazujące działanie gojenia ran |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8357675B2 (pl) |
| EP (1) | EP1910398B1 (pl) |
| AT (1) | ATE489398T1 (pl) |
| DE (1) | DE602006018471D1 (pl) |
| DK (1) | DK1910398T3 (pl) |
| ES (1) | ES2356668T3 (pl) |
| IT (1) | ITMI20051516A1 (pl) |
| PL (1) | PL1910398T3 (pl) |
| PT (1) | PT1910398E (pl) |
| WO (1) | WO2007014711A1 (pl) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1806131A3 (en) | 1996-07-22 | 2007-08-01 | Renovo Limited | Use of sex steroid function modulators to treat wounds and fibrotic disorders |
-
2005
- 2005-08-02 IT IT001516A patent/ITMI20051516A1/it unknown
-
2006
- 2006-07-28 PL PL06762874T patent/PL1910398T3/pl unknown
- 2006-07-28 PT PT06762874T patent/PT1910398E/pt unknown
- 2006-07-28 DE DE602006018471T patent/DE602006018471D1/de active Active
- 2006-07-28 AT AT06762874T patent/ATE489398T1/de active
- 2006-07-28 US US11/989,807 patent/US8357675B2/en active Active
- 2006-07-28 ES ES06762874T patent/ES2356668T3/es active Active
- 2006-07-28 DK DK06762874.3T patent/DK1910398T3/da active
- 2006-07-28 EP EP06762874A patent/EP1910398B1/en active Active
- 2006-07-28 WO PCT/EP2006/007488 patent/WO2007014711A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007014711A1 (en) | 2007-02-08 |
| ITMI20051516A1 (it) | 2007-02-03 |
| DE602006018471D1 (de) | 2011-01-05 |
| PT1910398E (pt) | 2011-02-25 |
| EP1910398B1 (en) | 2010-11-24 |
| US20100035796A1 (en) | 2010-02-11 |
| DK1910398T3 (da) | 2011-02-14 |
| ES2356668T3 (es) | 2011-04-12 |
| US8357675B2 (en) | 2013-01-22 |
| ATE489398T1 (de) | 2010-12-15 |
| EP1910398A1 (en) | 2008-04-16 |
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