PL1981572T3 - Dostarczanie inhibitora alfa-1 proteinazy do płuc - Google Patents

Dostarczanie inhibitora alfa-1 proteinazy do płuc

Info

Publication number
PL1981572T3
PL1981572T3 PL07706125T PL07706125T PL1981572T3 PL 1981572 T3 PL1981572 T3 PL 1981572T3 PL 07706125 T PL07706125 T PL 07706125T PL 07706125 T PL07706125 T PL 07706125T PL 1981572 T3 PL1981572 T3 PL 1981572T3
Authority
PL
Poland
Prior art keywords
alpha
proteinase inhibitor
pulmonary delivery
pulmonary
delivery
Prior art date
Application number
PL07706125T
Other languages
English (en)
Inventor
Shabtai Bauer
Manfred Keller
Martin Knoch
Original Assignee
Kamada Ltd
Pari Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kamada Ltd, Pari Pharma Gmbh filed Critical Kamada Ltd
Publication of PL1981572T3 publication Critical patent/PL1981572T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PL07706125T 2006-02-09 2007-02-08 Dostarczanie inhibitora alfa-1 proteinazy do płuc PL1981572T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US77146506P 2006-02-09 2006-02-09
US77365406P 2006-02-16 2006-02-16
PCT/IL2007/000182 WO2007091267A2 (en) 2006-02-09 2007-02-08 Pulmonary delivery of alpha-i proteinase inhibitor
EP07706125A EP1981572B1 (en) 2006-02-09 2007-02-08 Pulmonary delivery of alpha-i proteinase inhibitor

Publications (1)

Publication Number Publication Date
PL1981572T3 true PL1981572T3 (pl) 2013-05-31

Family

ID=38345545

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07706125T PL1981572T3 (pl) 2006-02-09 2007-02-08 Dostarczanie inhibitora alfa-1 proteinazy do płuc

Country Status (13)

Country Link
US (3) US7973005B2 (pl)
EP (3) EP1981572B1 (pl)
AU (2) AU2007213344B2 (pl)
BR (2) BRPI0707635A2 (pl)
CA (2) CA2641875C (pl)
DK (1) DK1981572T3 (pl)
ES (2) ES2664624T3 (pl)
HK (1) HK1198919A1 (pl)
MX (2) MX2008010173A (pl)
PL (1) PL1981572T3 (pl)
PT (1) PT1981572E (pl)
RU (2) RU2472524C2 (pl)
WO (2) WO2007091266A2 (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1981572B1 (en) * 2006-02-09 2012-11-21 Kamada Ltd. Pulmonary delivery of alpha-i proteinase inhibitor
US8551534B2 (en) 2007-10-10 2013-10-08 Parion Sciences, Inc. Inhaled hypertonic saline delivered by a heated nasal cannula
AU2010315325B2 (en) 2009-11-03 2014-11-27 Grifols Therapeutics Inc. Composition, method, and kit for alpha-1 proteinase inhibitor
PT2503995T (pt) 2009-11-24 2017-11-23 Grifols Therapeutics Inc Métodos de liofilização, composições e kits
US8945605B2 (en) * 2011-06-07 2015-02-03 Parion Sciences, Inc. Aerosol delivery systems, compositions and methods
US8778383B2 (en) 2011-06-07 2014-07-15 Parion Sciences, Inc. Methods of treatment
EP2793936A4 (en) * 2011-12-19 2015-05-27 Lfb Usa Inc RECOMBINANT HUMAN ALPHA-1-ANTITRYPINE FOR THE TREATMENT OF INFLAMMATORY DISEASES
KR20140108516A (ko) 2011-12-30 2014-09-11 그리폴스, 에스.에이. 폐 악화의 발현 또는 진행을 지연시키기 위한 알파1-프로테이나제 억제제
US20150272988A1 (en) 2012-03-07 2015-10-01 Advanced Inhalation Therapies (Ait) Ltd. Inhalation of nitric oxide for treating respiratory diseases
WO2013175007A1 (en) * 2012-05-25 2013-11-28 Inserm Agents for treating cystic fibrosis
JP6305994B2 (ja) 2012-06-08 2018-04-04 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 患者の肺機能をモニタするための方法及びシステム
US10034921B2 (en) 2013-02-13 2018-07-31 Laboratoire Français Du Fractionnement Et Des Biotechnologies Proteins with modified glycosylation and methods of production thereof
WO2016087582A1 (en) * 2014-12-03 2016-06-09 Institut National De La Sante Et De La Recherche Medicale (Inserm) Methods and pharmaceutical compositions for the prevention and/or treatment of acute exacerbations of chronic obstructive pulmonary disease
CA3024522C (en) 2016-05-31 2024-06-25 Polyphor Ag Beta-hairpin peptidomimetic with elastase inhibitory activity and aerosol dosage forms thereof
EP3348293A1 (en) 2017-01-17 2018-07-18 Carebay Europe Ltd. Medicament delivery device
WO2018154568A1 (en) 2017-02-21 2018-08-30 Kamada Ltd. Methods and uses of alpha 1-antitrypsin for early intervention in pulmonary diseases
ES2984415T3 (es) * 2017-12-12 2024-10-29 Kamada Ltd Métodos para inducir tolerancia inmunitaria y reducir la respuesta de anticuerpos anti-fármaco
WO2020157752A1 (en) * 2019-01-29 2020-08-06 Kamada Ltd Pharmaceutical aerosol composition
KR20230020952A (ko) 2020-04-01 2023-02-13 유니온 테라퓨틱스 에이/에스 치료
JP2023520229A (ja) 2020-04-01 2023-05-16 ユニオン・セラピューティクス・アー/エス 製剤

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4697003A (en) * 1985-11-01 1987-09-29 Miles Laboratories, Inc. Method of preparing alpha-1-proteinase inhibitor
US5093316A (en) 1986-12-24 1992-03-03 John Lezdey Treatment of inflammation
JP2656944B2 (ja) * 1987-04-30 1997-09-24 クーパー ラボラトリーズ タンパク質性治療剤のエアロゾール化
ATE131421T1 (de) * 1991-12-04 1995-12-15 The Technology Partnership Plc Vorrichtung und verfahren zur erzeugung von fluessigkeitstroepfchen
US5780440A (en) 1996-06-17 1998-07-14 Protease Sciences Inc. Treatment of pulmonary disease with protease inhibitors
OA11529A (en) * 1998-03-16 2004-05-07 Inhale Therapeutic Syst Aerosolized active agent delivery.
DE19953317C1 (de) 1999-11-05 2001-02-01 Pari Gmbh Inhalationsvernebler
US6462180B1 (en) * 1999-11-24 2002-10-08 Bayer Corporation Method of preparing α-1 proteinase inhibitor
EP1295647A1 (en) 2001-09-24 2003-03-26 The Technology Partnership Public Limited Company Nozzles in perforate membranes and their manufacture
DE60235883D1 (de) 2002-08-02 2010-05-20 Pari Pharma Gmbh Vorrichtung zur Erzeugung von Flüssigkeitströpfchen
DE10257381B4 (de) * 2002-12-09 2006-09-14 Pari GmbH Spezialisten für effektive Inhalation Inhalationstherapievorrichtung
RU2262343C2 (ru) * 2003-04-15 2005-10-20 ГОУ ВПО Омская Государственная Медицинская Академия Способ лечения гипоксии
PT1664123E (pt) 2003-09-22 2008-07-16 Kamada Ltd Preparação em larga escala de um inibidor da alfa-1 proteinase e sua utilização
ATE530165T1 (de) * 2003-11-14 2011-11-15 Baxter Int Alpha1-antitrypsin-zusammensetzungen und behandlungsverfahren unter verwendung dieser zusammensetzungen
EP1737499A4 (en) * 2004-03-09 2009-07-22 Arriva Pharmaceuticals Inc TREATMENT OF CHRONIC OBSTRUCTIVE LUNG DISEASE BY INHALATION OF LOW DOSES OF A PROTEASE HEMMER
EP1981572B1 (en) * 2006-02-09 2012-11-21 Kamada Ltd. Pulmonary delivery of alpha-i proteinase inhibitor

Also Published As

Publication number Publication date
US20090131305A1 (en) 2009-05-21
RU2008135580A (ru) 2010-03-20
BRPI0707634A2 (pt) 2011-05-10
US20120211005A1 (en) 2012-08-23
CA2641872A1 (en) 2007-08-16
EP1981531A2 (en) 2008-10-22
PT1981572E (pt) 2013-02-26
RU2433841C2 (ru) 2011-11-20
DK1981572T3 (da) 2013-03-04
WO2007091266A2 (en) 2007-08-16
MX2008010172A (es) 2009-09-07
ES2664624T3 (es) 2018-04-20
AU2007213344A1 (en) 2007-08-16
AU2007213344B2 (en) 2012-11-15
RU2472524C2 (ru) 2013-01-20
WO2007091267A3 (en) 2007-11-22
AU2007213343B2 (en) 2012-09-13
US7973005B2 (en) 2011-07-05
CA2641875C (en) 2016-10-04
WO2007091266A3 (en) 2007-11-15
EP1981572B1 (en) 2012-11-21
HK1198919A1 (en) 2015-06-19
AU2007213343A1 (en) 2007-08-16
CA2641875A1 (en) 2007-08-16
EP2740487A1 (en) 2014-06-11
MX2008010173A (es) 2009-02-12
EP1981572A2 (en) 2008-10-22
WO2007091267A2 (en) 2007-08-16
EP2740487B1 (en) 2018-02-28
ES2399449T3 (es) 2013-04-01
BRPI0707635A2 (pt) 2011-05-10
RU2008135582A (ru) 2010-03-20
US20090304604A1 (en) 2009-12-10

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