PL201988B1 - A new derivative of disubstituted fluorene and its preparation - Google Patents
A new derivative of disubstituted fluorene and its preparationInfo
- Publication number
- PL201988B1 PL201988B1 PL368089A PL36808904A PL201988B1 PL 201988 B1 PL201988 B1 PL 201988B1 PL 368089 A PL368089 A PL 368089A PL 36808904 A PL36808904 A PL 36808904A PL 201988 B1 PL201988 B1 PL 201988B1
- Authority
- PL
- Poland
- Prior art keywords
- preparation
- disubstituted fluorene
- formula
- new derivative
- new
- Prior art date
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1. Nowa pochodna dipodstawionego fluorenu o wzorze 1 i nazwie kwas 9,9-diheksadecylofluoreno-2,7-dikarboksylowy.1. A new derivative of disubstituted fluorene with formula 1 and the name 9,9-dihexadecylfluorene-2,7-dicarboxylic acid.
Description
Opis wynalazkuDescription of the invention
Przedmiotem wynalazku jest nowa pochodna dipodstawionego fluorenu i sposób jej wytwarzania.The present invention relates to a novel disubstituted fluorene derivative and a method of its preparation.
Nowy związek jest ważnym półproduktem w syntezie nowego dichlorku kwasu 9,9-diheksadecylofluoreno-2,7-dikarboksylowego.The new compound is an important intermediate in the synthesis of the new 9,9-dihexadecylfluorene-2,7-dicarboxylic acid dichloride.
Wynalazek dotyczy nowego związku o wzorze 1 i nazwie kwas 9,9-diheksadecylofluoreneno-2,7-dikarboksylowy.The invention relates to a novel compound of the formula I named 9,9-dihexadecylfluorenene-2,7-dicarboxylic acid.
Sposób wytwarzania nowego kwasu 9,9-diheksadecylofluoreneno-2,7-dikarboksylowego o wzorze 1, polega na reakcji 9,9-diheksadecylo-2,7-dicyjanofluorenu o wzorze 2 z 100% kwasem fosforowym w temperaturze około 170°C w atmosferze azotu.The method of producing the new 9,9-dihexadecylfluorenene-2,7-dicarboxylic acid of the formula 1 involves the reaction of 9,9-dihexadecyl-2,7-dicyanofluorene of the formula 2 with 100% phosphoric acid at a temperature of about 170 ° C in a nitrogen atmosphere .
Sposób według wynalazku jest przedstawiony w przykładzie wykonania i na schemacie reakcji.The process of the invention is shown in the embodiment and in the reaction scheme.
Do 1,0 g, tj. 1,5 mmola 9,9-diheksadecylo-2,7-dicyjanofluorenu dodaje się 17,5 ml 100% kwasu fosforowego w 2,5 ml wody.17.5 ml of 100% phosphoric acid in 2.5 ml of water are added to 1.0 g, ie 1.5 mmol of 9,9-dihexadecyl-2,7-dicyanofluorene.
Reagenty miesza się w temperaturze 170°C przez 12 godzin i prowadzi reakcję w atmosferze azotu.The reaction was stirred at 170 ° C for 12 hours and reacted under a nitrogen atmosphere.
Następnie mieszaninę reakcyjną wylewa się do 20 ml gorącej wody i odfiltrowuje osad.The reaction mixture was then poured into 20 ml of hot water and the precipitate was filtered off.
Surowy produkt poddaje się krystalizacji z metanolu.The crude product is crystallized from methanol.
Otrzymuje się 0,8 g, tj. 1,1 mmola bezbarwnych kryształków kwasu 9,9-diheksadecylofluoreno-2,7-dikarboksylowego.0.8 g, i.e. 1.1 mmol of colorless crystals of 9,9-dihexadecylfluorene-2,7-dicarboxylic acid are obtained.
Produkt posiada następujące właściwości fizyczne i spektralne: t.t. 210-213°C, rozpuszcza się w octanie etylu, metanolu, nie rozpuszcza si ę w benzenie, eterze etylowym.The product has the following physical and spectral properties: mp. 210-213 ° C, dissolved in ethyl acetate, methanol, insoluble in benzene, diethyl ether.
1H NMR(CDCl3), δ 10,9 (s, 2H), 8,3-7,9 (m, 6H), 2,4 (q, 4H, J = 7,1 Hz), 1,4-1,3 (m, 52H), 0,89 (6H, t, J = 6,8 Hz), 0,56-0,53 (m,4H). 1 H NMR (CDCl3) δ 10.9 (s, 2H), 8,3-7,9 (m, 6H), 2.4 (q, 4H, J = 7.1 Hz), 1,4- 1.3 (m, 52H), 0.89 (6H, t, J = 6.8Hz), 0.56-0.53 (m, 4H).
13C NMR, δ 166,6, 149,3, 143,1, 131,4, 129,3, 120,5, 54,9, 31,3, 29,7, 29,6, 29,5, 29,3, 29,2, 29,4, 29,1, 29,0, 19,7, 13,9. 13 C NMR δ 166.6, 149.3, 143.1, 131.4, 129.3, 120.5, 54.9, 31.3, 29.7, 29.6, 29.5, 29 , 3, 29.2, 29.4, 29.1, 29.0, 19.7, 13.9.
Obliczono dla C47H74O4: C 80,28, H 10,61; znaleziono: C 80,00, H, 10,50.Calculated for C47H74O4: C 80.28, H 10.61; found: C 80.00, H, 10.50.
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL368089A PL201988B1 (en) | 2004-05-19 | 2004-05-19 | A new derivative of disubstituted fluorene and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL368089A PL201988B1 (en) | 2004-05-19 | 2004-05-19 | A new derivative of disubstituted fluorene and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL368089A1 PL368089A1 (en) | 2005-11-28 |
| PL201988B1 true PL201988B1 (en) | 2009-05-29 |
Family
ID=37038022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL368089A PL201988B1 (en) | 2004-05-19 | 2004-05-19 | A new derivative of disubstituted fluorene and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL201988B1 (en) |
-
2004
- 2004-05-19 PL PL368089A patent/PL201988B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL368089A1 (en) | 2005-11-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4871740A (en) | Glycyrrhetic acid derivatives and use thereof | |
| JP2012006956A (en) | Method for preparing pyrazole-o-glycoside derivative and new intermediate of the method | |
| PL201988B1 (en) | A new derivative of disubstituted fluorene and its preparation | |
| KR20220156560A (en) | Synthesis of capsaicin derivatives | |
| CN106366081A (en) | Green synthesis method for bicyclic pyridone compound | |
| PL196238B1 (en) | New derivative of di-substituted fluorene and method for its manufacture | |
| PL201984B1 (en) | A new derivative of disubstituted fluorene and its preparation | |
| PL201987B1 (en) | New derivative of di-substituted fluorene and method for its manufacture | |
| JP4512100B2 (en) | Process for producing substituted benzopyran compounds | |
| JP2022513588A (en) | Hydrogenation process of oxime derivatives | |
| JPS60237039A (en) | Benzalacetophenone, its derivative and their production | |
| KR101411359B1 (en) | Method of mono ｎ-alkylation of aniline compounds | |
| Chen et al. | Synthesis of aminoalkyl-substituted polymethoxychalcone derivatives and their antiproliferative activities against three human cancer cell lines | |
| KR100911357B1 (en) | Method for preparing α-keto cyanophosphorane from carbonyl compound | |
| US6787653B2 (en) | Preparation process of biphenylcarboxylic acid amide derivatives | |
| KR100566318B1 (en) | Method for preparing carbazole-on derivatives | |
| JP6169721B2 (en) | Method for synthesizing hydrazine that can be used in the treatment of papillomavirus | |
| PL196234B1 (en) | New derivative of di-substituted fluorene and method for its manufacture | |
| PL196233B1 (en) | New derivative of di-substituted fluorene and method for its manufacture | |
| PL196225B1 (en) | New derivative of di-substituted fluorene and method for its manufacture | |
| PL197975B1 (en) | New derivative of di-substituted carbazole and method for its manufacture | |
| JP4192526B2 (en) | Production of coumarin compounds | |
| PL196235B1 (en) | New derivative of di-substituted fluorene and method for its manufacture | |
| JP4214692B2 (en) | Process for the production of mononitrated aromatic ethers | |
| KR100382715B1 (en) | Process for the preparation of 4-hydroxythiocoumarin and nitrogen analogues thereof |