PL2035385T3 - Inhibitory AKT (białkowa kinaza B) - Google Patents

Inhibitory AKT (białkowa kinaza B)

Info

Publication number
PL2035385T3
PL2035385T3 PL07798410T PL07798410T PL2035385T3 PL 2035385 T3 PL2035385 T3 PL 2035385T3 PL 07798410 T PL07798410 T PL 07798410T PL 07798410 T PL07798410 T PL 07798410T PL 2035385 T3 PL2035385 T3 PL 2035385T3
Authority
PL
Poland
Prior art keywords
akt
inhibitors
protein kinase
kinase
protein
Prior art date
Application number
PL07798410T
Other languages
English (en)
Inventor
Sajan Joseph
Renhua Li
Michael Ray Myers
Aktham Aburub
Jenny Pingqi Dai
Christopher Randall Schmid
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PL2035385T3 publication Critical patent/PL2035385T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
PL07798410T 2006-06-20 2007-06-12 Inhibitory AKT (białkowa kinaza B) PL2035385T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US80526006P 2006-06-20 2006-06-20
US88576507P 2007-01-19 2007-01-19
EP07798410A EP2035385B1 (en) 2006-06-20 2007-06-12 Inhibitors of akt (protein kinase b)
PCT/US2007/070945 WO2007149730A2 (en) 2006-06-20 2007-06-12 Inhibitors of akt (protein kinase b)

Publications (1)

Publication Number Publication Date
PL2035385T3 true PL2035385T3 (pl) 2010-06-30

Family

ID=38834248

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07798410T PL2035385T3 (pl) 2006-06-20 2007-06-12 Inhibitory AKT (białkowa kinaza B)

Country Status (28)

Country Link
US (1) US7998977B2 (pl)
EP (1) EP2035385B1 (pl)
JP (1) JP2009541335A (pl)
KR (1) KR101067551B1 (pl)
AR (1) AR061240A1 (pl)
AT (1) ATE455102T1 (pl)
AU (1) AU2007261120A1 (pl)
BR (1) BRPI0713136A2 (pl)
CA (1) CA2652612A1 (pl)
CL (1) CL2007001752A1 (pl)
DE (1) DE602007004333D1 (pl)
DK (1) DK2035385T3 (pl)
DO (1) DOP2008000053A (pl)
EA (1) EA015712B1 (pl)
EC (1) ECSP088992A (pl)
ES (1) ES2336630T3 (pl)
HR (1) HRP20100147T1 (pl)
IL (1) IL195005A0 (pl)
MA (1) MA30757B1 (pl)
MX (1) MX2008015904A (pl)
NO (1) NO20090289L (pl)
PE (1) PE20080338A1 (pl)
PL (1) PL2035385T3 (pl)
PT (1) PT2035385E (pl)
SI (1) SI2035385T1 (pl)
TN (1) TNSN08529A1 (pl)
TW (1) TW200812970A (pl)
WO (1) WO2007149730A2 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8217047B2 (en) 2008-05-27 2012-07-10 Dmi Acquisition Corp. Therapeutic methods and compounds
CA2810844C (en) 2010-09-07 2017-03-21 Dmi Acquisition Corp. Diketopiperazine compositions for the treatment of metabolic syndrome and related conditions
EP2765968A4 (en) 2011-10-10 2015-01-21 Ampio Pharmaceuticals Inc IMPLANTABLE MEDICINE PRODUCTS WITH INCREASED IMMUNO TOLERANCE AND PROCESSING AND IMPLANTATION METHODS
CA2846598C (en) 2011-10-10 2019-12-10 Ampio Pharmaceuticals, Inc. Treatment of degenerative joint disease
HK1198812A1 (en) 2011-10-28 2015-06-12 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
EA201500943A1 (ru) 2013-03-15 2016-08-31 Ампио Фармасьютикалс, Инк. Составы для мобилизации, хоуминга, размножения и дифференцировки стволовых клеток и способы применения составов
CA2938626A1 (en) 2013-07-26 2015-01-29 John Rothman Compositions to improve the therapeutic benefit of bisantrene
CA2958080A1 (en) 2014-08-18 2016-02-25 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
WO2016201605A1 (zh) * 2015-06-15 2016-12-22 廖勇 一种治疗乙型肝炎病毒的靶点
US11389512B2 (en) 2015-06-22 2022-07-19 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases
WO2017156350A1 (en) 2016-03-09 2017-09-14 K-Gen, Inc. Methods of cancer treatment
CA3186565A1 (en) * 2020-07-22 2022-01-27 Lei Miao Unit dosage composition of akt inhibitor
US20230271958A1 (en) * 2020-07-22 2023-08-31 Nanjing Chia Tai Tianqing Pharmaceutical Co., Ltd. SALT AND CRYSTAL FORM OF DIHYDROPYRIDO[2,3-d]PYRIMIDINE DERIVATE

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL136458A0 (en) 2000-05-30 2001-06-14 Peptor Ltd Protein kinase inhibitors
AU2004232682B2 (en) 2003-03-28 2006-12-07 Eli Lilly And Company Isoquinoline-5-sulfonic acid amides as inhibitors of Akt (protein kinase B)
GB0317315D0 (en) 2003-07-24 2003-08-27 Astex Technology Ltd Pharmaceutical compounds
US7449477B2 (en) * 2003-11-25 2008-11-11 Eli Lilly And Company 7-phenyl-isoquinoline-5-sulfonylamino derivatives as inhibitors of akt (protein kinase B)

Also Published As

Publication number Publication date
SI2035385T1 (sl) 2010-05-31
ES2336630T3 (es) 2010-04-14
AR061240A1 (es) 2008-08-13
DOP2008000053A (es) 2009-01-15
EA015712B1 (ru) 2011-10-31
WO2007149730A2 (en) 2007-12-27
US7998977B2 (en) 2011-08-16
CL2007001752A1 (es) 2008-01-18
CA2652612A1 (en) 2007-12-27
WO2007149730A3 (en) 2008-04-24
HRP20100147T1 (hr) 2010-04-30
EP2035385A2 (en) 2009-03-18
US20090221633A1 (en) 2009-09-03
DE602007004333D1 (de) 2010-03-04
NO20090289L (no) 2009-01-19
TW200812970A (en) 2008-03-16
DK2035385T3 (da) 2010-03-22
AU2007261120A1 (en) 2007-12-27
TNSN08529A1 (en) 2010-04-14
KR101067551B1 (ko) 2011-09-27
MA30757B1 (fr) 2009-10-01
PE20080338A1 (es) 2008-04-25
EA200970041A1 (ru) 2009-06-30
JP2009541335A (ja) 2009-11-26
ECSP088992A (es) 2009-01-30
EP2035385B1 (en) 2010-01-13
PT2035385E (pt) 2010-03-01
MX2008015904A (es) 2009-01-12
BRPI0713136A2 (pt) 2012-04-17
IL195005A0 (en) 2009-08-03
ATE455102T1 (de) 2010-01-15
KR20090015978A (ko) 2009-02-12

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