PL2057148T3 - Amidynowe pochodne 2-heteroarylochinazolin i chinolin, silne środki przeciwbólowe i środki przeciwzapalne - Google Patents
Amidynowe pochodne 2-heteroarylochinazolin i chinolin, silne środki przeciwbólowe i środki przeciwzapalneInfo
- Publication number
- PL2057148T3 PL2057148T3 PL06778076T PL06778076T PL2057148T3 PL 2057148 T3 PL2057148 T3 PL 2057148T3 PL 06778076 T PL06778076 T PL 06778076T PL 06778076 T PL06778076 T PL 06778076T PL 2057148 T3 PL2057148 T3 PL 2057148T3
- Authority
- PL
- Poland
- Prior art keywords
- compounds
- quinolines
- heteroaryl
- inflammatory
- treatment
- Prior art date
Links
- 150000001409 amidines Chemical class 0.000 title abstract 2
- 229940035676 analgesics Drugs 0.000 title abstract 2
- 239000000730 antalgic agent Substances 0.000 title abstract 2
- 229940111121 antirheumatic drug quinolines Drugs 0.000 title abstract 2
- 230000003389 potentiating effect Effects 0.000 title abstract 2
- 150000003248 quinolines Chemical class 0.000 title abstract 2
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 230000002757 inflammatory effect Effects 0.000 abstract 3
- 208000004296 neuralgia Diseases 0.000 abstract 2
- 208000021722 neuropathic pain Diseases 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 206010065390 Inflammatory pain Diseases 0.000 abstract 1
- 208000027520 Somatoform disease Diseases 0.000 abstract 1
- 230000016396 cytokine production Effects 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000027753 pain disease Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06778076A EP2057148B1 (en) | 2006-07-31 | 2006-07-31 | Amidine derivatives of 2-heteroaryl-quinazolines and quinolines; potent analgesics and anti-inflammatory agents |
| PCT/EP2006/064841 WO2008014815A1 (en) | 2006-07-31 | 2006-07-31 | Amidine derivatives of 2-heteroaryl-quinazolines and quinolines; potent analgesics and anti-inflammatory agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2057148T3 true PL2057148T3 (pl) | 2010-06-30 |
Family
ID=37075652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06778076T PL2057148T3 (pl) | 2006-07-31 | 2006-07-31 | Amidynowe pochodne 2-heteroarylochinazolin i chinolin, silne środki przeciwbólowe i środki przeciwzapalne |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7968558B2 (pl) |
| EP (1) | EP2057148B1 (pl) |
| JP (1) | JP4997289B2 (pl) |
| AT (1) | ATE453638T1 (pl) |
| CA (1) | CA2659689C (pl) |
| DE (1) | DE602006011515D1 (pl) |
| DK (1) | DK2057148T3 (pl) |
| ES (1) | ES2338458T3 (pl) |
| PL (1) | PL2057148T3 (pl) |
| PT (1) | PT2057148E (pl) |
| WO (1) | WO2008014815A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103153062B (zh) * | 2010-05-24 | 2015-07-15 | 因特利凯有限责任公司 | 杂环化合物及其用途 |
| WO2012116237A2 (en) | 2011-02-23 | 2012-08-30 | Intellikine, Llc | Heterocyclic compounds and uses thereof |
| CN102993109A (zh) * | 2012-12-03 | 2013-03-27 | 浙江工业大学 | 一种脒化合物的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0004054D0 (sv) * | 2000-11-06 | 2000-11-06 | Astrazeneca Ab | N-type calcium channel antagonists for the treatment of pain |
| ITTO20040125A1 (it) | 2004-03-01 | 2004-06-01 | Rotta Research Lab | Nuove amidine eterocicliche inibitrici la produzione di ossido d'azoto (no) ad attivita' antinfiammatoria ed analgesica |
| WO2006058201A2 (en) * | 2004-11-23 | 2006-06-01 | Reddy Us Therapeutics, Inc. | Heterocyclic and bicyclic compounds, compositions and methods |
-
2006
- 2006-07-31 PL PL06778076T patent/PL2057148T3/pl unknown
- 2006-07-31 WO PCT/EP2006/064841 patent/WO2008014815A1/en not_active Ceased
- 2006-07-31 CA CA2659689A patent/CA2659689C/en not_active Expired - Fee Related
- 2006-07-31 DE DE602006011515T patent/DE602006011515D1/de active Active
- 2006-07-31 ES ES06778076T patent/ES2338458T3/es active Active
- 2006-07-31 US US12/376,066 patent/US7968558B2/en not_active Expired - Fee Related
- 2006-07-31 AT AT06778076T patent/ATE453638T1/de active
- 2006-07-31 EP EP06778076A patent/EP2057148B1/en not_active Not-in-force
- 2006-07-31 PT PT06778076T patent/PT2057148E/pt unknown
- 2006-07-31 DK DK06778076.7T patent/DK2057148T3/da active
- 2006-07-31 JP JP2009522101A patent/JP4997289B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| PT2057148E (pt) | 2010-03-01 |
| DE602006011515D1 (de) | 2010-02-11 |
| ES2338458T3 (es) | 2010-05-07 |
| EP2057148A1 (en) | 2009-05-13 |
| JP4997289B2 (ja) | 2012-08-08 |
| JP2009545538A (ja) | 2009-12-24 |
| CA2659689C (en) | 2014-02-18 |
| EP2057148B1 (en) | 2009-12-30 |
| CA2659689A1 (en) | 2008-02-07 |
| US20090227609A1 (en) | 2009-09-10 |
| ATE453638T1 (de) | 2010-01-15 |
| US7968558B2 (en) | 2011-06-28 |
| WO2008014815A1 (en) | 2008-02-07 |
| DK2057148T3 (da) | 2010-04-26 |
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