PL207242A1 - Sposob otrzymywania nowych,podstawionych kwasow alfa-fluorometylo-alfa-aminoalkanokarboksylowych - Google Patents

Sposob otrzymywania nowych,podstawionych kwasow alfa-fluorometylo-alfa-aminoalkanokarboksylowych

Info

Publication number
PL207242A1
PL207242A1 PL20724278A PL20724278A PL207242A1 PL 207242 A1 PL207242 A1 PL 207242A1 PL 20724278 A PL20724278 A PL 20724278A PL 20724278 A PL20724278 A PL 20724278A PL 207242 A1 PL207242 A1 PL 207242A1
Authority
PL
Poland
Prior art keywords
alpha
aminoalkanocarboxylic
fluoromethyl
acids
obtaining new
Prior art date
Application number
PL20724278A
Other languages
English (en)
Other versions
PL115731B1 (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/802,391 external-priority patent/US4325961A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PL207242A1 publication Critical patent/PL207242A1/pl
Publication of PL115731B1 publication Critical patent/PL115731B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
PL1978207242A 1977-06-01 1978-05-31 Process for manufacturing novel,substituted alpha-fluoro-methyl-alpha-aminoalkanocarboxylic acids PL115731B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80238977A 1977-06-01 1977-06-01
US05/802,391 US4325961A (en) 1977-06-01 1977-06-01 Fluorinated amino acids

Publications (2)

Publication Number Publication Date
PL207242A1 true PL207242A1 (pl) 1979-04-23
PL115731B1 PL115731B1 (en) 1981-04-30

Family

ID=27122442

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1978207242A PL115731B1 (en) 1977-06-01 1978-05-31 Process for manufacturing novel,substituted alpha-fluoro-methyl-alpha-aminoalkanocarboxylic acids

Country Status (26)

Country Link
JP (1) JPS5416423A (pl)
AR (1) AR223463A1 (pl)
AT (1) AT360509B (pl)
AU (1) AU518479B2 (pl)
CA (1) CA1120040A (pl)
CH (1) CH639639A5 (pl)
DD (1) DD138651A5 (pl)
DE (1) DE2824116A1 (pl)
DK (1) DK149841C (pl)
ES (1) ES470296A1 (pl)
FI (1) FI66840C (pl)
FR (1) FR2392958A1 (pl)
GB (1) GB1602525A (pl)
GR (1) GR64495B (pl)
HK (1) HK18184A (pl)
HU (1) HU181911B (pl)
IE (1) IE46983B1 (pl)
IT (1) IT1104709B (pl)
LU (1) LU79750A1 (pl)
NL (1) NL190485C (pl)
NO (1) NO147382C (pl)
NZ (1) NZ187377A (pl)
PL (1) PL115731B1 (pl)
PT (1) PT68102B (pl)
SE (1) SE7806440L (pl)
YU (1) YU129178A (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1091661A (en) * 1977-07-11 1980-12-16 Philippe Bey .alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS
IL59481A0 (en) * 1977-07-11 1980-05-30 Merrell Toraude & Co -halomethyl amino acids
ZA783273B (en) * 1977-07-11 1979-06-27 Merrell Toraude & Co A-halomethyl amino acids
US4315095A (en) * 1977-07-28 1982-02-09 Merrell Toraude Et Compagnie α-Halomethyl derivatives of amino acids
ATE3282T1 (de) * 1978-07-24 1983-05-15 Merck & Co. Inc. Alpha-difluormethyl-alpha-aminosaeuren und sie enthaltende pharmazeutische zusammensetzung.
IE49522B1 (en) * 1979-04-26 1985-10-16 Merrell Toraude & Co Alpha-halomethylaminoacids
IL60591A (en) * 1979-07-26 1985-02-28 Merrell Toraude & Co Alkenyl fluoromethyl ketimine magnesium halides and process for their preparation
ZA813018B (en) * 1980-05-09 1982-05-26 Merrell Toraude & Co Fluoromethylated tyrosine methyl ester
SE460517B (sv) * 1980-06-16 1989-10-23 Merrell Pharma Inc Anvaendning av en foerening foer framstaellning av ett laekemedel foer behandling av infektioner orsakade av trypanosoma brucei
US4421767A (en) * 1981-06-01 1983-12-20 Merrell Toraude Et Compagnie Compounds and methods for treating depression
GB9325368D0 (en) * 1993-12-10 1994-02-16 Univ Bristol Organic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046300A (en) * 1960-10-21 1962-07-24 Merck & Co Inc alpha-trifluoromethyloxyphenylalanines

Also Published As

Publication number Publication date
JPS5416423A (en) 1979-02-07
NO147382B (no) 1982-12-20
CH639639A5 (en) 1983-11-30
IE46983B1 (en) 1983-11-16
IE781078L (en) 1978-12-01
PT68102A (en) 1978-06-01
HK18184A (en) 1984-03-09
FI66840C (fi) 1984-12-10
AR223463A1 (es) 1981-08-31
JPS641474B2 (pl) 1989-01-11
LU79750A1 (fr) 1979-02-02
NO781892L (no) 1978-12-04
FI781674A7 (fi) 1978-12-02
IT7849637A0 (it) 1978-05-31
FI66840B (fi) 1984-08-31
NL190485B (nl) 1993-10-18
DE2824116C2 (pl) 1989-04-27
AU3658678A (en) 1979-12-06
SE7806440L (sv) 1978-12-02
PL115731B1 (en) 1981-04-30
ES470296A1 (es) 1979-09-16
DK149841C (da) 1987-04-21
FR2392958A1 (fr) 1978-12-29
AU518479B2 (en) 1981-10-01
IT1104709B (it) 1985-10-28
DD138651A5 (de) 1979-11-14
CA1120040A (en) 1982-03-16
AT360509B (de) 1981-01-12
HU181911B (en) 1983-11-28
YU129178A (en) 1983-01-21
FR2392958B1 (pl) 1980-10-24
NO147382C (no) 1983-03-30
DK149841B (da) 1986-10-13
DK237978A (da) 1979-01-19
PT68102B (en) 1982-06-08
DE2824116A1 (de) 1978-12-14
GB1602525A (en) 1981-11-11
NL7805981A (nl) 1978-12-05
NL190485C (nl) 1994-03-16
NZ187377A (en) 1981-05-15
ATA393278A (de) 1980-06-15
GR64495B (en) 1980-03-31

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