PL2083007T3 - Sole tiotropium, sposoby ich wytwarzania oraz zawierające je kompozycje farmaceutyczne - Google Patents

Sole tiotropium, sposoby ich wytwarzania oraz zawierające je kompozycje farmaceutyczne

Info

Publication number: PL2083007T3
Authority: PL; Poland
Prior art keywords: same; formulations containing; creating; tiotropium salts; medicinal formulations
Prior art date: 2003-11-03

Application number

PL09157299T

Other languages

English (en)

Inventor

Rolf Banholzer

Peter Sieger

Waldemar Pfrengle

Original Assignee

Boehringer Ingelheim Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-11-03

Filing date

2004-10-29

Publication date

2013-09-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34530661&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2083007(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-10-29 Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int

2013-09-30 Publication of PL2083007T3 publication Critical patent/PL2083007T3/pl

Links

238000009472 formulation Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
239000000203 mixture Substances 0.000 title 1
LERNTVKEWCAPOY-DZZGSBJMSA-N tiotropium Chemical class O([C@H]1C[C@@H]2[N+]([C@H](C1)[C@@H]1[C@H]2O1)(C)C)C(=O)C(O)(C=1SC=CC=1)C1=CC=CS1 LERNTVKEWCAPOY-DZZGSBJMSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pulmonology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL09157299T 2003-11-03 2004-10-29 Sole tiotropium, sposoby ich wytwarzania oraz zawierające je kompozycje farmaceutyczne PL2083007T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP03025076		2003-11-03
EP04791030A EP1682543B1 (de)	2003-11-03	2004-10-29	Verfahren zur herstellung neuer tiotropiumsalze
EP09157299.0A EP2083007B1 (de)	2003-11-03	2004-10-29	Tiotropiumsalze, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittelformulierungen

Publications (1)

Publication Number	Publication Date
PL2083007T3 true PL2083007T3 (pl)	2013-09-30

Family

ID=34530661

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL09157299T PL2083007T3 (pl)	2003-11-03	2004-10-29	Sole tiotropium, sposoby ich wytwarzania oraz zawierające je kompozycje farmaceutyczne

Country Status (28)

Country	Link
US (1)	US20050096341A1 (pl)
EP (5)	EP2319844A1 (pl)
JP (1)	JP5165245B2 (pl)
KR (1)	KR20060102561A (pl)
CN (3)	CN1875020B (pl)
AR (1)	AR046318A1 (pl)
AT (1)	ATE478071T1 (pl)
AU (1)	AU2004285685B2 (pl)
CA (1)	CA2544357A1 (pl)
CO (1)	CO5690554A2 (pl)
DE (1)	DE502004011562D1 (pl)
DK (2)	DK2083007T3 (pl)
EA (1)	EA012369B1 (pl)
EC (2)	ECSP066545A (pl)
ES (2)	ES2350981T3 (pl)
IL (1)	IL175127A (pl)
MY (1)	MY145166A (pl)
NO (1)	NO20061441L (pl)
NZ (1)	NZ547523A (pl)
PE (1)	PE20050485A1 (pl)
PL (1)	PL2083007T3 (pl)
RS (1)	RS20060293A (pl)
SG (1)	SG149876A1 (pl)
TW (1)	TW200523263A (pl)
UA (1)	UA82414C2 (pl)
UY (1)	UY28589A1 (pl)
WO (1)	WO2005042528A1 (pl)
ZA (1)	ZA200602343B (pl)

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EA012326B1 (ru) *	2003-11-03	2009-08-28	Бёрингер Ингельхайм Интернациональ Гмбх	Способ получения солей тиотропия, соли тиотропия, а также содержащие их лекарственные композиции
EP1896026B1 (en) *	2005-06-15	2013-10-09	Boehringer Ingelheim International GmbH	Process for preparing tiotropium salts, tiotropium salts as such and pharmaceutical compositions thereof
WO2006134022A1 (en) *	2005-06-17	2006-12-21	Boehringer Ingelheim International Gmbh	Mrp iv inhibitors for the treatment of respiratory diseases
DE102005035112A1 (de) *	2005-07-27	2007-02-15	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neues Verfahren zur Herstellung von Tiotropiumsalzen unter Anwendung von in organischen Lösungsmitteln löslichen N-Methylscopiniumsalzen
MX2007009987A (es) *	2005-12-19	2007-10-02	Sicor Inc	Bromuro de tiotropio puro y estable.
US9108962B2 (en)	2005-12-19	2015-08-18	Sicor, Inc.	Forms of tiotropium bromide and processes for preparation thereof
US20070167480A1 (en) *	2005-12-19	2007-07-19	Sicor Inc.	Pure and stable tiotropium bromide
MX2007009988A (es) *	2005-12-19	2008-02-22	Sicor Inc	Formas novedosas de bromuro de tiotropio y procesos para su preparacion.
US20080051582A1 (en) *	2006-07-10	2008-02-28	Sicor Inc.	Process for the preparation of tiotropium bromide
EP1925295A1 (de) *	2006-11-22	2008-05-28	Boehringer Ingelheim Pharma GmbH & Co. KG	Stabile Pulverformulierung enthaltend ein Anticholinergikum
WO2008089852A1 (de) *	2007-01-26	2008-07-31	Boehringer Ingelheim Pharma Gmbh & Co.Kg	Neues verfahren zur herstellung von tiotropiumsalzen
EP1953156A1 (de) *	2007-01-29	2008-08-06	Boehringer Ingelheim Pharma GmbH & Co. KG	Verfahren zur Herstellung von Scopiniumsalzen
EP2411008B1 (en) *	2009-03-27	2017-03-22	Mahmut Bilgic	Complexes of tiotropium with improved properties of solubility and stability
PL388070A1 (pl) *	2009-05-19	2010-11-22	Adamed Spółka Z Ograniczoną Odpowiedzialnością	Nowe sole tiotropium
CZ201241A3 (cs) *	2012-01-20	2013-07-31	Zentiva, K.S.	Nové polymorfní formy tiotropium jodidu a zpusob jejich prípravy
EP2819669B1 (de) *	2012-02-28	2021-04-21	Boehringer Ingelheim International GmbH	Neue treibgashaltige tiotropium-formulierung

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US5610163A (en) *	1989-09-16	1997-03-11	Boehringer Ingelheim Gmbh	Esters of thienyl carboxylic acids and amino alcohols and their quaternization products
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US20020193394A1 (en) *	2001-03-13	2002-12-19	Bernd Disse	Compounds for treating inflammatory diseases
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DE10212264A1 (de)	2002-03-20	2003-10-02	Boehringer Ingelheim Pharma	Kristallines Mikronisat, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels
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EA012326B1 (ru) *	2003-11-03	2009-08-28	Бёрингер Ингельхайм Интернациональ Гмбх	Способ получения солей тиотропия, соли тиотропия, а также содержащие их лекарственные композиции
US7968717B2 (en) *	2003-11-03	2011-06-28	Boehringer Ingelhein International Gmbh	Crystalline anhydrate with anticholinergic efficacy
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EP1896026B1 (en) *	2005-06-15	2013-10-09	Boehringer Ingelheim International GmbH	Process for preparing tiotropium salts, tiotropium salts as such and pharmaceutical compositions thereof

2004
- 2004-10-29 AU AU2004285685A patent/AU2004285685B2/en not_active Expired
- 2004-10-29 CN CN2004800325224A patent/CN1875020B/zh not_active Expired - Lifetime
- 2004-10-29 DK DK09157299.0T patent/DK2083007T3/da active
- 2004-10-29 CN CN200910165195.4A patent/CN101648950B/zh not_active Expired - Lifetime
- 2004-10-29 DE DE502004011562T patent/DE502004011562D1/de not_active Expired - Lifetime
- 2004-10-29 ES ES04791030T patent/ES2350981T3/es not_active Expired - Lifetime
- 2004-10-29 CN CN201210447516.1A patent/CN102964344B/zh not_active Expired - Lifetime
- 2004-10-29 DK DK04791030.2T patent/DK1682543T3/da active
- 2004-10-29 ES ES09157299T patent/ES2422730T3/es not_active Expired - Lifetime
- 2004-10-29 KR KR1020067010833A patent/KR20060102561A/ko not_active Ceased
- 2004-10-29 EP EP10180198A patent/EP2319844A1/de not_active Withdrawn
- 2004-10-29 PE PE2004001046A patent/PE20050485A1/es not_active IP Right Cessation
- 2004-10-29 RS YUP-2006/0293A patent/RS20060293A/sr unknown
- 2004-10-29 AT AT04791030T patent/ATE478071T1/de active
- 2004-10-29 EP EP09157299.0A patent/EP2083007B1/de not_active Expired - Lifetime
- 2004-10-29 SG SG200900492-0A patent/SG149876A1/en unknown
- 2004-10-29 EA EA200600854A patent/EA012369B1/ru not_active IP Right Cessation
- 2004-10-29 EP EP04791030A patent/EP1682543B1/de not_active Expired - Lifetime
- 2004-10-29 UY UY28589A patent/UY28589A1/es not_active Application Discontinuation
- 2004-10-29 EP EP10180177A patent/EP2322522A1/de not_active Withdrawn
- 2004-10-29 UA UAA200605765A patent/UA82414C2/uk unknown
- 2004-10-29 US US10/976,688 patent/US20050096341A1/en not_active Abandoned
- 2004-10-29 CA CA002544357A patent/CA2544357A1/en not_active Abandoned
- 2004-10-29 NZ NZ547523A patent/NZ547523A/xx not_active IP Right Cessation
- 2004-10-29 PL PL09157299T patent/PL2083007T3/pl unknown
- 2004-10-29 JP JP2006537209A patent/JP5165245B2/ja not_active Expired - Lifetime
- 2004-10-29 WO PCT/EP2004/012270 patent/WO2005042528A1/de not_active Ceased
- 2004-10-29 EP EP10180191A patent/EP2336127A1/de not_active Withdrawn
- 2004-11-01 MY MYPI20044523A patent/MY145166A/en unknown
- 2004-11-02 TW TW093133400A patent/TW200523263A/zh unknown
- 2004-11-03 AR ARP040104039A patent/AR046318A1/es not_active Application Discontinuation
2006
- 2006-03-22 ZA ZA200602343A patent/ZA200602343B/en unknown
- 2006-03-30 NO NO20061441A patent/NO20061441L/no not_active Application Discontinuation
- 2006-04-24 IL IL175127A patent/IL175127A/en active IP Right Grant
- 2006-05-02 CO CO06041175A patent/CO5690554A2/es not_active Application Discontinuation
- 2006-05-03 EC EC2006006545A patent/ECSP066545A/es unknown
- 2006-05-03 EC EC2006006544A patent/ECSP066544A/es unknown

Also Published As

Publication number	Publication date
WO2005042528A1 (de)	2005-05-12
HK1099753A1 (zh)	2007-08-24
NZ547523A (en)	2009-07-31
RS20060293A (sr)	2008-08-07
DK2083007T3 (da)	2013-07-29
EP2322522A1 (de)	2011-05-18
UY28589A1 (es)	2005-06-30
AU2004285685A1 (en)	2005-05-12
CN1875020B (zh)	2010-04-28
US20050096341A1 (en)	2005-05-05
ZA200602343B (en)	2007-12-27
CN102964344B (zh)	2014-12-31
DK1682543T3 (da)	2010-12-13
ECSP066545A (es)	2006-10-17
IL175127A0 (en)	2006-09-05
ECSP066544A (es)	2006-10-17
EP1682543B1 (de)	2010-08-18
CN101648950B (zh)	2014-05-07
JP2007509895A (ja)	2007-04-19
DE502004011562D1 (de)	2010-09-30
CA2544357A1 (en)	2005-05-12
CN101648950A (zh)	2010-02-17
TW200523263A (en)	2005-07-16
ES2422730T3 (es)	2013-09-13
CO5690554A2 (es)	2006-10-31
NO20061441L (no)	2006-07-12
CN102964344A (zh)	2013-03-13
CN1875020A (zh)	2006-12-06
SG149876A1 (en)	2009-02-27
UA82414C2 (uk)	2008-04-10
AU2004285685B2 (en)	2011-03-24
KR20060102561A (ko)	2006-09-27
EP2336127A1 (de)	2011-06-22
PE20050485A1 (es)	2005-10-05
EA012369B1 (ru)	2009-10-30
IL175127A (en)	2011-10-31
ATE478071T1 (de)	2010-09-15
EP2319844A1 (de)	2011-05-11
ES2350981T3 (es)	2011-01-28
EP2083007B1 (de)	2013-04-24
AR046318A1 (es)	2005-11-30
EP2083007A1 (de)	2009-07-29
JP5165245B2 (ja)	2013-03-21
EA200600854A1 (ru)	2006-10-27
EP1682543A1 (de)	2006-07-26
MY145166A (en)	2011-12-30

Publication	Publication Date	Title
HRP20150039T1 (hr)	2015-06-05	Farmaceutske formulacije koje sadrže metilnaltrekson
EP1648327A4 (en)	2013-11-13	ORAL DEVICES AND METHODS OF CONTROLLED MEDICAMENT DELIVERY
PL378065A1 (pl)	2006-02-20	Podstawione związki N-aryloheterocykliczne, sposób ich wytwarzania oraz ich zastosowanie jako środków leczniczych
PL1690550T3 (pl)	2013-01-31	Środek do leczenia międzybłoniaka
AU2002319653A1 (en)	2003-03-03	Method for oral drug delivery
IL174496A0 (en)	2006-08-01	Aerosol formulation for inhalation, containing an anticholinergic agent
PL2083007T3 (pl)	2013-09-30	Sole tiotropium, sposoby ich wytwarzania oraz zawierające je kompozycje farmaceutyczne
EP1467758A4 (en)	2007-11-14	PREPARATION OF IMMUNOCONJUGATES
PL377495A1 (pl)	2006-02-06	Stały lek do stosowania doustnego
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