PL2086332T3 - Mezenchymalne komórki macierzyste pochodzące ze szpiku kostnego jako źródło neuralnych komórek progenitorowych - Google Patents

Mezenchymalne komórki macierzyste pochodzące ze szpiku kostnego jako źródło neuralnych komórek progenitorowych

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Publication number
PL2086332T3
PL2086332T3 PL07867349T PL07867349T PL2086332T3 PL 2086332 T3 PL2086332 T3 PL 2086332T3 PL 07867349 T PL07867349 T PL 07867349T PL 07867349 T PL07867349 T PL 07867349T PL 2086332 T3 PL2086332 T3 PL 2086332T3
Authority
PL
Poland
Prior art keywords
source
stem cells
bone marrow
mesenchymal stem
derived mesenchymal
Prior art date
Application number
PL07867349T
Other languages
English (en)
Inventor
Saud A. Sadiq
Violane K. Harris
Original Assignee
Multiple Sclerosis Research Center Of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Multiple Sclerosis Research Center Of New York filed Critical Multiple Sclerosis Research Center Of New York
Publication of PL2086332T3 publication Critical patent/PL2086332T3/pl

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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/08—Coculture with; Conditioned medium produced by cells of the nervous system
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
    • C12N2506/1353—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from bone marrow mesenchymal stem cells (BM-MSC)

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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
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  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL07867349T 2006-11-03 2007-11-02 Mezenchymalne komórki macierzyste pochodzące ze szpiku kostnego jako źródło neuralnych komórek progenitorowych PL2086332T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85651506P 2006-11-03 2006-11-03
PCT/US2007/023184 WO2008057443A2 (en) 2006-11-03 2007-11-02 Bone marrow-derived mesenchymal stem cells as a source of neural progenitors
EP07867349.8A EP2086332B1 (en) 2006-11-03 2007-11-02 Bone marrow-derived mesenchymal stem cells as a source of neural progenitors

Publications (1)

Publication Number Publication Date
PL2086332T3 true PL2086332T3 (pl) 2018-07-31

Family

ID=39365076

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07867349T PL2086332T3 (pl) 2006-11-03 2007-11-02 Mezenchymalne komórki macierzyste pochodzące ze szpiku kostnego jako źródło neuralnych komórek progenitorowych

Country Status (15)

Country Link
US (5) US8642331B2 (pl)
EP (2) EP3031326A3 (pl)
CA (1) CA2668200C (pl)
CY (1) CY1120115T1 (pl)
DK (1) DK2086332T3 (pl)
ES (1) ES2663875T3 (pl)
HR (1) HRP20180533T1 (pl)
HU (1) HUE036745T2 (pl)
LT (1) LT2086332T (pl)
MX (1) MX2009004776A (pl)
PL (1) PL2086332T3 (pl)
PT (1) PT2086332T (pl)
RS (1) RS57083B1 (pl)
SI (1) SI2086332T1 (pl)
WO (1) WO2008057443A2 (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE036745T2 (hu) 2006-11-03 2018-07-30 Multiple Sclerosis Res Center Of New York Csontvelõ eredetû mesenchimális õssejtek, mint a neurális progenitor sejtek forrásai
US9301975B2 (en) 2009-05-01 2016-04-05 Biocardia, Inc. Method of preparing autologous cells and method of use for therapy
US20120020931A1 (en) 2010-06-02 2012-01-26 Rutgers, The State University Of New Jersey Therapeutic encapsulated embryonic stem cells and mesenchymal stromal cells
BR112013003169B1 (pt) 2010-08-18 2022-05-24 Theresa Deisher Uso de um agente terapêutico que inibe a ligação de células-tronco a tecido linfóide
WO2012048093A2 (en) 2010-10-08 2012-04-12 Osiris Therapeutics, Inc. Enhanced msc preparations
WO2012070964A1 (ru) * 2010-11-22 2012-05-31 Farber Boris Slavinovich Модифицированные олигопептиды с противораковыми свойствами и способ их получения
EP3354725B1 (en) * 2013-10-14 2019-12-04 Hadasit Medical Research Services and Development Ltd. Terminally differentiated neuronal lineages and uses thereof
WO2015143074A1 (en) * 2014-03-20 2015-09-24 University Of Southern California Brain cancer immunotherapy
WO2016168993A1 (en) 2015-04-22 2016-10-27 Innolife Co., Ltd. Methods of tissue repair and regeneration
WO2016205371A1 (en) * 2015-06-15 2016-12-22 Mayo Foundation For Medical Education And Research Using autologous mesenchymal stem cells to treat multiple system atrophy
EP3359647A1 (en) 2015-10-08 2018-08-15 Neurona Therapeutics Inc. Neural precursor cell populations and uses thereof
EP3478300B1 (en) 2016-06-30 2022-08-24 Stem Cell Medicine Ltd. Treatment of inflammatory bowel disease with long acting glatiramer and adipose-derived stem cells
EP3624815A4 (en) 2017-05-15 2021-01-20 Stem Cell Medicine Ltd. TREATMENT OF MULTIPLE SCLEROSIS WITH LONG-ACTING GLATIRAMER AND ADAPTIVE STEM CELLS
IL269893B2 (en) 2017-05-15 2023-10-01 Stem Cell Medicine Ltd Treatment of multiple sclerosis with adipose-derived stem cells
WO2019102268A1 (en) 2017-11-22 2019-05-31 Mesoblast International Sarl Cellular compositions and methods of treatment i
JP7391181B2 (ja) 2019-07-26 2023-12-04 プレクソジェン インコーポレイテッド 人工多能性幹細胞（ｉＰＳＣ）由来間葉系幹細胞の前駆細胞、及びその製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7037719B1 (en) * 1999-02-12 2006-05-02 Stemcells California, Inc. Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations
US8017112B2 (en) * 1999-05-14 2011-09-13 Henry Ford Health System Transplantation of bone marrow stromal cells for treatment of neurodegenerative diseases
US20040208858A1 (en) * 2000-04-12 2004-10-21 Gihan Tennekoon Therapeutic uses for mesenchymal stromal cells
EP1452586B1 (en) * 2001-10-30 2012-05-30 Nc Medical Research Inc. Method of inducing differentiation of mesodermal stem cells into nervous system cells
EP2465924A3 (en) * 2005-06-16 2013-01-02 Ramot at Tel-Aviv University Ltd. Isolated cells and populations comprising same for the treament of cns diseases
HUE036745T2 (hu) 2006-11-03 2018-07-30 Multiple Sclerosis Res Center Of New York Csontvelõ eredetû mesenchimális õssejtek, mint a neurális progenitor sejtek forrásai

Also Published As

Publication number Publication date
EP2086332A4 (en) 2010-08-11
EP3031326A3 (en) 2016-09-14
EP2086332B1 (en) 2018-01-10
SI2086332T1 (en) 2018-06-29
CA2668200C (en) 2017-04-18
CA2668200A1 (en) 2008-05-15
EP3031326A2 (en) 2016-06-15
LT2086332T (lt) 2018-04-25
ES2663875T3 (es) 2018-04-17
WO2008057443A9 (en) 2008-07-17
RS57083B1 (sr) 2018-06-29
US20150064145A1 (en) 2015-03-05
US9328329B2 (en) 2016-05-03
US9657268B2 (en) 2017-05-23
HRP20180533T1 (hr) 2018-05-18
HUE036745T2 (hu) 2018-07-30
CY1120115T1 (el) 2018-12-12
PT2086332T (pt) 2018-04-04
US20110236357A1 (en) 2011-09-29
US20140308745A1 (en) 2014-10-16
US8642331B2 (en) 2014-02-04
EP2086332A2 (en) 2009-08-12
DK2086332T3 (en) 2018-04-16
MX2009004776A (es) 2009-07-14
WO2008057443A2 (en) 2008-05-15
US20100166712A1 (en) 2010-07-01
WO2008057443A3 (en) 2008-11-20
US20150118198A1 (en) 2015-04-30

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