PL2125714T3 - Chlorowodorek 5-[3-(3-hydroksyfenoksy)azetydyn-1-ylo]-5-metylo-2,2-difenyloheksanamidu - Google Patents

Chlorowodorek 5-[3-(3-hydroksyfenoksy)azetydyn-1-ylo]-5-metylo-2,2-difenyloheksanamidu

Info

Publication number: PL2125714T3
Authority: PL; Poland
Prior art keywords: diphenylhexanamide; hydroxyphenoxy; azetidin; methyl; hydrochloride salt
Prior art date: 2007-03-16

Application number

PL08719316T

Other languages

English (en)

Inventor

Paul Alan Glossop

Kim James

Original Assignee

Pfizer Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-03-16

Filing date

2008-03-06

Publication date

2011-10-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39591485&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2125714(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-03-06 Application filed by Pfizer Ltd filed Critical Pfizer Ltd

2011-10-31 Publication of PL2125714T3 publication Critical patent/PL2125714T3/pl

Links

QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 title 1
WGOJWDWKHJHXSV-UHFFFAOYSA-N 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide Chemical compound C1C(OC=2C=C(O)C=CC=2)CN1C(C)(C)CCC(C(N)=O)(C=1C=CC=CC=1)C1=CC=CC=C1 WGOJWDWKHJHXSV-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL08719316T 2007-03-16 2008-03-06 Chlorowodorek 5-[3-(3-hydroksyfenoksy)azetydyn-1-ylo]-5-metylo-2,2-difenyloheksanamidu PL2125714T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US89516307P	2007-03-16	2007-03-16
PCT/IB2008/000622 WO2008135819A1 (en)	2007-03-16	2008-03-06	Hydrochloride salt of 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2- diphenylhexanamide
EP08719316A EP2125714B1 (en)	2007-03-16	2008-03-06	Hydrochloride salt of 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2- diphenylhexanamide

Publications (1)

Publication Number	Publication Date
PL2125714T3 true PL2125714T3 (pl)	2011-10-31

Family

ID=39591485

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL08719316T PL2125714T3 (pl)	2007-03-16	2008-03-06	Chlorowodorek 5-[3-(3-hydroksyfenoksy)azetydyn-1-ylo]-5-metylo-2,2-difenyloheksanamidu

Country Status (23)

Country	Link
US (1)	US8263583B2 (pl)
EP (1)	EP2125714B1 (pl)
JP (1)	JP4277051B2 (pl)
KR (1)	KR101120227B1 (pl)
CN (2)	CN103351367B (pl)
AR (1)	AR065714A1 (pl)
AT (1)	ATE512132T1 (pl)
AU (1)	AU2008247095B2 (pl)
BR (1)	BRPI0808413A2 (pl)
CA (1)	CA2678683C (pl)
CY (1)	CY1111701T1 (pl)
DK (1)	DK2125714T3 (pl)
ES (1)	ES2364727T3 (pl)
IL (1)	IL200403A (pl)
MX (1)	MX2009009952A (pl)
NZ (1)	NZ579056A (pl)
PL (1)	PL2125714T3 (pl)
PT (1)	PT2125714E (pl)
RU (1)	RU2422439C2 (pl)
SI (1)	SI2125714T1 (pl)
TW (1)	TWI348907B (pl)
WO (1)	WO2008135819A1 (pl)
ZA (1)	ZA200906462B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2011063366A1 (en)	2009-11-23	2011-05-26	Palatin Technologies, Inc.	Melanocortin-1 receptor-specific cyclic peptides
JP2013511554A (ja)	2009-11-23	2013-04-04	パラティンテクノロジーズ，インコーポレイテッド	メラノコルチン−１受容体特異的線状ペプチド
EP2578570A1 (en)	2011-10-07	2013-04-10	Almirall, S.A.	Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.
EP2641900A1 (en)	2012-03-20	2013-09-25	Almirall, S.A.	Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
WO2018167804A1 (en)	2017-03-15	2018-09-20	Mylan Laboratories Limited	Novel polymorphs of (5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide hydrochloride
US10342786B2 (en)	2017-10-05	2019-07-09	Fulcrum Therapeutics, Inc.	P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
WO2019071147A1 (en)	2017-10-05	2019-04-11	Fulcrum Therapeutics, Inc.	INHIBITORS OF KINASE P38 REDUCING EXPRESSION OF DUX4 GENE AND DOWNSTREAM GENES FOR THE TREATMENT OF FSHD
WO2020261160A1 (en) *	2019-06-25	2020-12-30	Mylan Laboratories Limited	Methods and intermediates for preparing hydrochloride salt of 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide
CN116033893A (zh) *	2020-06-26	2023-04-28	迈兰制药英国有限公司	包含5-[3-(3-羟基苯氧基)氮杂环丁烷-1-基]-5-甲基-2,2-二苯基己酰胺的制剂
CN113577059B (zh) *	2021-08-02	2022-05-20	山东大学齐鲁医院(青岛)	一种用于小儿哮喘的活性药物
WO2025095813A1 (ru) *	2023-11-03	2025-05-08	Общество С Ограниченной Ответственностью "Валента-Интеллект"	Новые соединения

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE235903T1 (de) *	1996-12-02	2003-04-15	Kyorin Seiyaku Kk	Neue derivate von n-substituierten pyrrolidin derivaten und deren herstellungsverfahren
JPH11100366A (ja)	1997-09-29	1999-04-13	Kyorin Pharmaceut Co Ltd	新規ｎ−置換環状アミン誘導体及びその製造法
DE10064398A1 (de) *	2000-12-21	2002-06-27	Aventis Pharma Gmbh	Neue Diphenylazetidinone, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
WO2007034325A1 (en) *	2005-09-21	2007-03-29	Pfizer Limited	Carboxamide derivatives as muscarinic receptor antagonists
US20100160279A1 (en) *	2006-09-22	2010-06-24	Pfizer Inc	Azetidine Derivatives as Muscarinic Receptor Antagonists

2008
- 2008-03-06 PT PT08719316T patent/PT2125714E/pt unknown
- 2008-03-06 AU AU2008247095A patent/AU2008247095B2/en active Active
- 2008-03-06 MX MX2009009952A patent/MX2009009952A/es active IP Right Grant
- 2008-03-06 ES ES08719316T patent/ES2364727T3/es active Active
- 2008-03-06 WO PCT/IB2008/000622 patent/WO2008135819A1/en not_active Ceased
- 2008-03-06 EP EP08719316A patent/EP2125714B1/en active Active
- 2008-03-06 CN CN201310280277.XA patent/CN103351367B/zh active Active
- 2008-03-06 KR KR1020097019239A patent/KR101120227B1/ko not_active Expired - Fee Related
- 2008-03-06 AT AT08719316T patent/ATE512132T1/de active
- 2008-03-06 CN CN200880008581A patent/CN101641327A/zh active Pending
- 2008-03-06 CA CA2678683A patent/CA2678683C/en active Active
- 2008-03-06 BR BRPI0808413-0A patent/BRPI0808413A2/pt not_active Application Discontinuation
- 2008-03-06 DK DK08719316.5T patent/DK2125714T3/da active
- 2008-03-06 SI SI200830366T patent/SI2125714T1/sl unknown
- 2008-03-06 RU RU2009134512/04A patent/RU2422439C2/ru active
- 2008-03-06 US US12/530,573 patent/US8263583B2/en active Active
- 2008-03-06 PL PL08719316T patent/PL2125714T3/pl unknown
- 2008-03-06 NZ NZ579056A patent/NZ579056A/en not_active IP Right Cessation
- 2008-03-13 AR ARP080101025A patent/AR065714A1/es not_active Application Discontinuation
- 2008-03-14 TW TW097109223A patent/TWI348907B/zh not_active IP Right Cessation
- 2008-03-14 JP JP2008065066A patent/JP4277051B2/ja not_active Expired - Fee Related
2009
- 2009-08-13 IL IL200403A patent/IL200403A/en not_active IP Right Cessation
- 2009-09-16 ZA ZA200906462A patent/ZA200906462B/xx unknown
2011
- 2011-07-08 CY CY20111100664T patent/CY1111701T1/el unknown

Also Published As

Publication number	Publication date
MX2009009952A (es)	2009-10-08
JP2009001543A (ja)	2009-01-08
ATE512132T1 (de)	2011-06-15
EP2125714A1 (en)	2009-12-02
IL200403A (en)	2014-08-31
WO2008135819A1 (en)	2008-11-13
TW200904408A (en)	2009-02-01
AR065714A1 (es)	2009-06-24
RU2009134512A (ru)	2011-03-20
NZ579056A (en)	2011-07-29
AU2008247095A1 (en)	2008-11-13
RU2422439C2 (ru)	2011-06-27
ZA200906462B (en)	2010-06-30
US20100113409A1 (en)	2010-05-06
KR101120227B1 (ko)	2012-03-20
CN103351367B (zh)	2015-06-10
CY1111701T1 (el)	2015-10-07
WO2008135819A8 (en)	2009-08-27
BRPI0808413A2 (pt)	2014-07-15
CN101641327A (zh)	2010-02-03
CN103351367A (zh)	2013-10-16
SI2125714T1 (sl)	2011-10-28
DK2125714T3 (da)	2011-07-25
PT2125714E (pt)	2011-07-14
HK1189591A1 (en)	2014-06-13
EP2125714B1 (en)	2011-06-08
CA2678683A1 (en)	2008-11-13
CA2678683C (en)	2012-05-15
AU2008247095B2 (en)	2012-12-13
TWI348907B (en)	2011-09-21
JP4277051B2 (ja)	2009-06-10
US8263583B2 (en)	2012-09-11
KR20090110944A (ko)	2009-10-23
IL200403A0 (en)	2010-04-29
ES2364727T3 (es)	2011-09-13

Publication	Publication Date	Title
IL200403A0 (en)	2010-04-29	Hydrochloride salt of 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2- diphenylhexanamide
AP2010005180A0 (en)	2010-04-30	5-substituted 2-(alkoxymethyl)furans
IL212186A0 (en)	2011-06-30	Fungicidal heterocyclic compounds
ZA201103887B (en)	2012-10-31	Isoxazole derivatives for use as fungicides
IL224109A (en)	2015-06-30	Isoxazole derivatives for use as fungicides
ZA200806350B (en)	2009-11-25	Stable, concentrated herbicidal compositions
AP2010005364A0 (en)	2010-08-31	Novel heterocyclic compounds.
ZA200904108B (en)	2010-04-28	Pyrido-pyrazine derivatives useful as herbicidal compounds
IL207854A0 (en)	2010-12-30	Crystal forms of 5-[3-(2,5-dichloro-4, 6-dimethyl-1-oxy-pyridine-3-yl)[1,2,4]oxadiazol-5-yl]-3-nit robenzene-1,2-diol
IL206765A0 (en)	2010-12-30	4,5-dihydro-oxazol-2-yl-amine derivatives
IL209423A0 (en)	2011-01-31	4,5-dihydro-oxazol-2-yl derivatives
ZA200809557B (en)	2010-01-27	2-(pyridin-2-yl)-pyrimidines for use as fungicides
ZA200801788B (en)	2009-07-29	Controlling torsional shaft oscillation
IL229712A (en)	2015-09-24	The aryl sulfonamide compounds are converted into two positions 2 and 5
PT2268635E (pt)	2015-10-06	Compostos heterocíclicos
IL205289A0 (en)	2010-12-30	Amino 1, 2, 4 - triazole derivatives as modulators of mglur5
IL215727A0 (en)	2012-01-31	2,5-disubstituted arylsulfonamide ccr3 antagonists
IL214110A0 (en)	2011-08-31	2,3-diaryl-or heteroaryl-substituted 1,1,1-trifluoro-2-hydroxypropyl compounds
PT2523963E (pt)	2014-11-06	Derivados de oxazolopirimidina substituídos em 2,5 como agonistas do edg-1
IL194351A0 (en)	2009-08-03	3-(pyridin-2-yl)-[1,2,4]-triazines for use as fungicides
EP2189445A4 (en)	2011-08-03	FIVE-GLASS HETEROCYCLIC CONNECTION
IL213328A0 (en)	2011-07-31	Regeneration of 2,2'-cyclopropylidene-bis (oxazolines)
HK1155153A (en)	2012-05-11	1, 2 disubstituted heterocyclic compounds
AU2007900027A0 (en)	2007-01-18	Heterocyclic compounds
AU2008903041A0 (en)	2008-07-03	Feedback loop biosensor