PL2144618T5 - Bio-skuteczne kompozycje oleju z kryla - Google Patents

Bio-skuteczne kompozycje oleju z kryla

Info

Publication number
PL2144618T5
PL2144618T5 PL08718910.6T PL08718910T PL2144618T5 PL 2144618 T5 PL2144618 T5 PL 2144618T5 PL 08718910 T PL08718910 T PL 08718910T PL 2144618 T5 PL2144618 T5 PL 2144618T5
Authority
PL
Poland
Prior art keywords
oil compositions
krill oil
bioeffective
bioeffective krill
compositions
Prior art date
Application number
PL08718910.6T
Other languages
English (en)
Other versions
PL2144618T3 (pl
Inventor
Inge Bruheim
Mikko Griinari
Snorre Tilseth
Sebastiano Banni
Jeffrey Cohn
Daniele Mancinelli
Original Assignee
Aker Biomarine Human Ingredients As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39577593&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2144618(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aker Biomarine Human Ingredients As filed Critical Aker Biomarine Human Ingredients As
Publication of PL2144618T3 publication Critical patent/PL2144618T3/pl
Publication of PL2144618T5 publication Critical patent/PL2144618T5/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/612—Crustaceans, e.g. crabs, lobsters, shrimps, krill or crayfish; Barnacles
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/006—Refining fats or fatty oils by extraction
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Insects & Arthropods (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physiology (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL08718910.6T 2007-03-28 2008-03-28 Bio-skuteczne kompozycje oleju z kryla PL2144618T5 (pl)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US92048307P 2007-03-28 2007-03-28
US97505807P 2007-09-25 2007-09-25
US98344607P 2007-10-29 2007-10-29
US2407208P 2008-01-28 2008-01-28
PCT/GB2008/001080 WO2008117062A1 (en) 2007-03-28 2008-03-28 Bioeffective krill oil compositions
EP08718910.6A EP2144618B2 (en) 2007-03-28 2008-03-28 Bioeffective krill oil compositions

Publications (2)

Publication Number Publication Date
PL2144618T3 PL2144618T3 (pl) 2014-03-31
PL2144618T5 true PL2144618T5 (pl) 2025-07-21

Family

ID=39577593

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08718910.6T PL2144618T5 (pl) 2007-03-28 2008-03-28 Bio-skuteczne kompozycje oleju z kryla

Country Status (10)

Country Link
US (16) US9034388B2 (pl)
EP (2) EP2612672A1 (pl)
AU (1) AU2008231570C1 (pl)
CA (1) CA2682068C (pl)
DK (1) DK2144618T4 (pl)
FI (1) FI2144618T4 (pl)
HR (1) HRP20130551T1 (pl)
PL (1) PL2144618T5 (pl)
PT (1) PT2144618E (pl)
WO (1) WO2008117062A1 (pl)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0648721B1 (en) * 1993-10-15 1998-07-08 Fina Research S.A. Process for the purification of medium-chain olefins
AU2007320183B2 (en) * 2006-11-16 2013-06-06 Pronova Biopharma Norge As Process for production of omega-3 rich marine phospholipids from krill
PL2144618T5 (pl) 2007-03-28 2025-07-21 Aker Biomarine Human Ingredients As Bio-skuteczne kompozycje oleju z kryla
US8697138B2 (en) 2007-03-28 2014-04-15 Aker Biomarine As Methods of using krill oil to treat risk factors for cardiovascular, metabolic, and inflammatory disorders
AU2014100741B4 (en) * 2007-08-29 2014-09-11 Aker Biomarine Antarctic As Processes and products thereof
RU2504373C2 (ru) 2008-03-26 2014-01-20 ОРАМЕД Лтд. Способы и композиции для перорального введения протеинов
CN102170795B (zh) 2008-09-12 2014-10-29 翡翠渔业公司 从磷虾生产蛋白质浓缩物时减少氟含量的方法
US8557297B2 (en) 2008-09-12 2013-10-15 Olympic Seafood, As Method for processing crustaceans and products thereof
US9814256B2 (en) * 2009-09-14 2017-11-14 Rimfrost Technologies As Method for processing crustaceans to produce low fluoride/low trimethyl amine products thereof
KR20180010325A (ko) 2008-09-26 2018-01-30 니폰스이산가부시키가이샤 지질의 농축 방법
DK2384192T3 (en) * 2009-01-05 2018-01-08 Calanus As BIOLOGICAL OIL COMPOSITION, FORMULATIONS CONTAINING THE OIL COMPOSITION, AND ITS USE TO PREVENT OR TREAT CARDIOVASCULAR DISEASE
WO2010097701A1 (en) * 2009-02-26 2010-09-02 Aker Biomarine Asa Low viscosity phospholipid compositions
US8372812B2 (en) 2009-02-26 2013-02-12 Aker Biomarine Asa Phospholipid and protein tablets
CA2763647A1 (en) * 2009-05-28 2010-12-02 Aker Biomarine Asa Methods of using krill oil to treat risk factors for metabolic, cardiovascular, and inflammatory disorders
JP2012529503A (ja) * 2009-06-12 2012-11-22 カラナス エーエス オイル組成物、オイル組成物を含む製剤、及び内蔵脂肪の蓄積を減らし、ブドウ糖耐性を向上させて肥満関連疾患及び障害を予防又は治療するためのその使用
US20130295171A1 (en) 2009-07-23 2013-11-07 U.S NUTRACEUTICALS, LLC d/b/a Valensa International Krill oil and reacted astaxanthin composition and associated method
EP2464240A1 (en) * 2009-08-10 2012-06-20 K.D. Pharma Bexbach GMBH Phytanic acid fractionation process, fatty acid products and use thereof
AU2013203423A1 (en) * 2009-10-29 2013-05-02 Acasti Pharma, Inc. Concentrated therapeutic phospholipid compositions
EP3335713B1 (en) * 2009-10-29 2022-08-31 Acasti Pharma, Inc. Concentrated therapeutic phospholipid compositions
NZ599618A (en) 2009-10-30 2014-08-29 Tharos Ltd Solvent-free process for obtaining phospholipids and neutral enriched krill oils
US20110223246A1 (en) * 2010-03-10 2011-09-15 Joar Opheim Docosahexaenoic acid bound in phospholipids and method of recovering same from a natural source
US8273248B1 (en) 2010-04-06 2012-09-25 Heliae Development, Llc Extraction of neutral lipids by a two solvent method
AU2011237710A1 (en) 2010-04-06 2012-10-18 Heliae Development, Llc Methods of and systems for producing biofuels
GB201006012D0 (en) * 2010-04-09 2010-05-26 Ayanda As Composition
US8663704B2 (en) * 2010-04-30 2014-03-04 U.S. Nutraceuticals, LLC Composition and method to improve blood lipid profiles and optionally reduce low density lipoprotein (LDL) per-oxidation in humans
US9763897B2 (en) 2010-04-30 2017-09-19 U.S. Nutraceuticals, LLC Therapeutic astaxanthin and phospholipid composition and associated method
KR100992995B1 (ko) 2010-05-03 2010-11-09 연세대학교 산학협력단 피페로날의 신규한 용도
GB201009368D0 (en) 2010-06-04 2010-07-21 Sana Pharma As Dietary formulations
CN103096904B (zh) * 2010-09-01 2016-03-09 日本水产株式会社 酒精性伤害缓解剂
US20120231087A1 (en) 2011-03-07 2012-09-13 Olympic Seafood Compositions And Methods for Nutritional Supplementation
SI2697345T1 (sl) * 2011-04-14 2016-08-31 Polar Omega A/S Proces za izolacijo fosfolipida
CN103608022A (zh) * 2011-05-31 2014-02-26 日本水产株式会社 脑功能改善剂
US8895074B2 (en) 2011-06-15 2014-11-25 Stable Solutions Llc Therapeutic application of parenteral krill oil
US10052352B2 (en) 2011-06-15 2018-08-21 Stable Solutions Llc Therapeutic application of parenteral krill oil
CN103608023A (zh) * 2011-06-15 2014-02-26 稳定解决方案有限责任公司 磷虾油的胃肠外治疗应用
WO2013033618A1 (en) 2011-09-02 2013-03-07 Arctic Nutrition As Lipid compositions with high dha content
US9200236B2 (en) 2011-11-17 2015-12-01 Heliae Development, Llc Omega 7 rich compositions and methods of isolating omega 7 fatty acids
AU2012347606A1 (en) * 2011-12-08 2014-06-26 Metaproteomics, Llc Supplemented oil compositions and methods for improved health
AU2015100022B4 (en) * 2012-01-03 2016-01-07 Rimfrost Technologies As Method for processing crustaceans to produce low fluoride/low trimethyl amine products thereof
CN102603791B (zh) * 2012-02-21 2014-12-24 山东师范大学 一种南极磷虾磷脂酰乙醇胺产品的制备方法
EP2825057B8 (en) 2012-03-12 2020-06-24 Innolipid As Oxidixable fatty acid composition delivery form
AU2013291680C9 (en) * 2012-07-17 2017-10-19 Aker Biomarine Antarctic As Concentration of omega-3 polyunsaturated fatty acids in krill oil
WO2014045127A2 (en) 2012-09-19 2014-03-27 Aker Biomarine As Omega-3 phospholipid supplements for females
WO2014057362A2 (en) 2012-09-24 2014-04-17 Aker Biopharma As Omega -3 compositions
US20140088047A1 (en) * 2012-09-24 2014-03-27 Aker Bioassist As Use of long chain polyunsaturated fatty acid derivatives to treat sickle cell disease
CN104902921A (zh) 2013-01-03 2015-09-09 奥拉姆德有限公司 用于治疗nafld、肝性脂肪变性及其后遗症的方法和组合物
WO2014184655A1 (en) 2013-02-07 2014-11-20 Olympic Seafood As Methods for using crustacean phospholipid-peptide-protein complexes
WO2014140873A2 (en) 2013-03-14 2014-09-18 Aker Biomarine As Omega- 3 phospholipid supplements for improved brain maturity
WO2014138920A1 (fr) * 2013-03-14 2014-09-18 Institut De Recherche Sur Les Zones Cotieres (Irzc) Procédé d'extraction de solides organiques et d'huile d'organismes marins enrichis en astaxanthine
AU2014203179C1 (en) 2013-06-14 2017-05-04 Aker Biomarine Antarctic As Lipid extraction processes
GB201400431D0 (en) * 2014-01-10 2014-02-26 Aker Biomarine As Phospholipid compositions and their preparation
GB201402450D0 (en) 2014-02-12 2014-03-26 Aker Biomarine As Liquid phospholipid-containing compositions for preperation of pharmaceuticals
GB201402457D0 (en) 2014-02-12 2014-03-26 Aker Biomarine As Capsules containing high doses of phospholipids
GB201407345D0 (en) 2014-04-25 2014-06-11 Aker Biomarine As Krill Phospholipid compositions
EP3137070B1 (en) 2014-04-30 2020-04-15 Aker BioMarine Antarctic AS Krill oil preparations and their uses
CN104208117A (zh) * 2014-09-15 2014-12-17 天津蒙特立医疗科技有限责任公司 一种具有维护肝脏功能的植物提取物复方产品
US10059904B2 (en) 2014-11-14 2018-08-28 Tharos Ltd. Solvent-free process for obtaining phospholipids and neutral enriched krill oils using melting and evaporation
US11147841B2 (en) 2014-12-19 2021-10-19 Aker Biomarine Antarctic As Enhanced omega-3 formulations
WO2016128830A1 (en) 2015-02-11 2016-08-18 Aker Biomarine Antarctic As Lipid extraction processes
EP3256553A2 (en) 2015-02-11 2017-12-20 Aker Biomarine Antarctic AS Lipid compositions
GB201505938D0 (en) 2015-04-08 2015-05-20 Reckitt Benckiser Llc Compositions comprising C0-Q10, krill oil and vitamin D
US10328105B2 (en) 2015-05-27 2019-06-25 Rimfrost Technologies As Flowable concentrated phospholipid krill oil composition
AU2016308696B2 (en) 2015-08-17 2021-01-07 BIOMAR, Group Methods for improving health of farmed fish
WO2017031502A1 (en) * 2015-08-20 2017-02-23 Avoca, Inc. Method for increasing muscle growth using krill extract
IT201600124013A1 (it) * 2016-12-06 2018-06-06 Solarpharm Srl Prodotto alimentare a base di astaxantina
CN111432654A (zh) 2017-12-04 2020-07-17 雾凇科技有限公司 从甲壳类捕获物中生产蛋白质磷脂复合物的方法
NZ755776A (en) 2017-12-22 2020-05-29 Pharmalink International Ltd Lipid combinations
CN108179053B (zh) * 2018-01-26 2021-07-20 日照职业技术学院 一种高品质南极磷虾油的制备方法
EP3749339B1 (en) 2018-01-30 2022-08-03 Aker Biomarine Antarctic As Marine protein hydrolysate with low fluoride and trimethylamin content
BR112021010240A2 (pt) * 2018-11-30 2021-08-17 Evonik Operations Gmbh preparação que compreende uma dispersão de fosfolipídeos e sais de ácidos graxos
JP7188028B2 (ja) * 2018-11-30 2022-12-13 株式会社リコー キャビネット一体型画像形成装置
CA3129365C (en) * 2019-02-12 2023-01-03 Acasti Pharma, Inc. Process of producing concentrated therapeutic phospholipid composition from krill extracts containing high level of free fatty acids
CN110575680A (zh) * 2019-09-19 2019-12-17 福建启元堂生物技术有限公司 一种双超萃取海洋营养物的方法
WO2021086172A1 (en) 2019-10-31 2021-05-06 N.V. Nutricia Composition comprising epa, ma and leucine for improving muscle function
CN111876246B (zh) * 2020-08-05 2023-06-20 赵福江 一种磷虾油提取方法
CN114073864B (zh) * 2022-01-19 2022-05-24 华南理工大学 一种四液相体系同步萃取分离原料中多组分的方法
GB2617574A (en) * 2022-04-12 2023-10-18 Aker Biomarine Antarctic As Supplemented krill meal and uses thereof
AU2023375007A1 (en) 2022-11-01 2025-05-08 Aker Biomarine Human Ingredients As Phospholipid compositions for delivery of therapeutic compounds
US20250249380A1 (en) * 2024-02-06 2025-08-07 AKSO Marine Biotech Inc. Extraction of omega-3 fatty acids from lipid-rich marine organism using a supercritical fluid

Family Cites Families (131)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2652235A (en) 1951-11-29 1953-09-15 Beatrice L Samuelsen Heating attachment for electric food mixers
GB921537A (en) 1959-05-22 1963-03-20 Mario Meroni Process for extracting fatty substances from animal material
JPS58850B2 (ja) 1975-03-14 1983-01-08 日魯漁業株式会社 南氷洋産オキアミの加工方法
JPS51125774A (en) 1975-04-25 1976-11-02 Nichiro Gyogyo Kk Method of processing euphausiid from antarctic ocean
JPS51125773A (en) 1975-04-25 1976-11-02 Amao Suisan Kk Method of producing fish meat extract
JPS5842741B2 (ja) 1976-03-19 1983-09-21 日研化学株式会社 蛋白質液及び蛋白質粉末の製造方法
PL110567B1 (en) 1976-09-14 1980-07-31 Przedsieb Polowow Dalekom Method of obtaining the meat from marine crustaceans,specially from antarctic krill
US4119619A (en) * 1976-12-16 1978-10-10 Sergei Vasilievich Rogozhin Emulsification method for the processing of kriel to produce protein, lipids and chitin
CA1098900A (en) 1977-12-14 1981-04-07 Sergei V. Rogozhin Method for the processing of krill to produce protein, lipids and chitin
JPS54160789A (en) 1978-06-12 1979-12-19 Shimose Shokuhin Kk Fish meal producing system plant by batch type and complete closed system
WO1982002819A1 (en) 1981-02-16 1982-09-02 Hansen Bent Schiott A food product on the basis of fish flesh and a process for the preparation thereof
GB2097014B (en) 1981-04-13 1984-08-01 Baikoff Eugene Marc Alexandre Ultrasonic extraction of vegetable oil
US4505936A (en) 1983-09-14 1985-03-19 Louisiana State University Process for the utilization of shellfish waste
JPS60153779A (ja) 1984-01-24 1985-08-13 Hohnen Oil Co Ltd 栄養補助食品
US4814111A (en) 1984-02-13 1989-03-21 Air Products And Chemicals, Inc. Process for purification of phospholipids
US4714571A (en) 1984-02-13 1987-12-22 The Liposome Company, Inc. Process for purification of phospholipids
JPS611222A (ja) 1984-06-08 1986-01-07 日本電気株式会社 電源スイツチ回路
US5006281A (en) 1985-03-26 1991-04-09 Century Laboratories, Inc. Process for the production of a marine animal oil
DK157452C (da) 1985-04-12 1990-05-21 Matcon Radgivende Ing Firma Fremgangsmaade til udvinding af chitin fra chitinkilder, hvori den findes sammen med eller bundet til proteinstoffer
JPS61281159A (ja) 1985-06-06 1986-12-11 Shiseido Co Ltd 橙色色素の製造法
US4749522A (en) 1985-10-31 1988-06-07 Angio-Medical Corporation Supercritical fluid extraction of animal derived materials
FR2596060B1 (fr) 1986-03-20 1988-07-08 Guillot Bernard Extraction d'huile de graines oleagineuses par ultrasons
JPS6323819A (ja) 1986-07-16 1988-02-01 Kao Corp 血小板凝集抑制剤
JPS642665A (en) 1987-06-25 1989-01-06 Matsushita Electric Works Ltd Warm bath device
SE8703064D0 (sv) 1987-08-06 1987-08-06 Viggo Mohr Method for isolating active enzyme preparations from animal tissues
JP2524217B2 (ja) 1988-04-18 1996-08-14 マルハ株式会社 脳機能改善組成物、学習能力増強剤、記憶力増強剤、痴呆予防剤または痴呆治療剤
SE8801701D0 (sv) 1988-05-05 1988-05-05 Pharmacia Ab Production technology based on enzymic method
JP2619491B2 (ja) 1988-08-11 1997-06-11 サントリー株式会社 アスタキサンチン含有組成物
NO176323C (no) 1988-11-18 1995-03-15 Mikalsen Ester Framgangsmåte for utvinning av astaxantin, beslektede karotenoider og astaxantin-estere fra krill, reker og andre krepsedyr
JP2909508B2 (ja) 1989-02-14 1999-06-23 マルハ株式会社 オキアミリン脂質の分取方法
JPH02215352A (ja) 1989-02-16 1990-08-28 Advance Co Ltd 食物の味覚改善方法
DE3918082A1 (de) 1989-06-02 1991-01-24 Max Planck Gesellschaft Mittel gegen autoimmunerkrankungen
JPH0381692A (ja) 1989-08-23 1991-04-08 Hitachi Ltd 磁場封じ込め型核融合装置の燃料供給装置
JP2861246B2 (ja) 1990-04-26 1999-02-24 松下電器産業株式会社 スイッチング電源装置
JP2963152B2 (ja) * 1990-06-28 1999-10-12 クロリンエンジニアズ株式会社 オキアミからの色素の抽出分離方法
JP2524217Y2 (ja) 1990-12-29 1997-01-29 ニチバン株式会社 医療用粘着テ−プ
SE9101642D0 (sv) 1991-05-30 1991-05-30 Kabi Pharmacia Ab Phospholipids
JP3081692B2 (ja) 1991-11-28 2000-08-28 クロリンエンジニアズ株式会社 オキアミからの色素の抽出分離方法
SE9201628D0 (sv) 1992-05-22 1992-05-22 Phairson Medical Ab Pharmaceutical composition
GB9301629D0 (en) 1993-01-27 1993-03-17 Scotia Holdings Plc Formulations containing unsaturated fatty acids
JP3467794B2 (ja) 1993-03-09 2003-11-17 日本油脂株式会社 学習能向上剤
JP3486778B2 (ja) 1993-04-02 2004-01-13 三菱ウェルファーマ株式会社 アルツハイマー病予防治療剤
JPH07242621A (ja) 1994-03-02 1995-09-19 Nippon Oil Co Ltd カロチノイド化合物の抽出方法
JPH08231391A (ja) 1995-02-24 1996-09-10 Kanagawa Kagaku Kenkyusho:Kk 痴呆症状改善薬
FR2731015B1 (fr) 1995-02-24 1997-05-30 Sci Sartone Procede d'enrichissement enzymatique d'huiles d'origine marine et les triglycerides d'acides gras polyinsatures ainsi obtenus
JP3344887B2 (ja) 1995-12-22 2002-11-18 池田食研株式会社 高度不飽和脂肪酸含有油脂の濃縮方法
JP3611222B2 (ja) 1996-01-26 2005-01-19 池田食研株式会社 高度不飽和脂肪酸類含有油脂の過酸化物低減方法
US5672370A (en) 1996-04-16 1997-09-30 The University Of British Columbia Method of producing a dried krill product
WO1997039759A2 (en) 1996-04-24 1997-10-30 Brigham And Women's Hospital Omega-3 fatty acids and omega-3 phosphatidylcholine in the treatment of bipolar disorder
JP3678317B2 (ja) 1996-05-21 2005-08-03 クロリンエンジニアズ株式会社 エイコサペンタエン酸含有物の濃縮方法
CA2197137A1 (en) 1997-02-07 1998-08-07 Biozyme Systems Inc. Method and apparatus for co-drying krill hydrolysate, liquid marine protein and dry carrier
US6555155B2 (en) 1996-10-21 2003-04-29 Biozyme Systems, Inc. Method and apparatus for harvesting, digestion and dehydrating of krill hydrolysates and co-drying and processing of such hydrolysates
FR2757021B1 (fr) 1996-12-17 1999-01-22 Sea Oil Procede et installation d'extraction d'huile de poisson et produits obtenus
IL121320A (en) 1997-02-23 2000-12-06 Ibr Ltd Extracts from cells or tissue of organisms which are capable of entering dormancy for inhibition of proliferation of target cells or tissue
JP3408958B2 (ja) 1997-10-24 2003-05-19 旭化成株式会社 魚介類由来の有用物質を含む組成物およびその有用物質の製造方法
CA2251265A1 (en) * 1998-10-21 2000-04-21 Universite De Sherbrooke Process for lipid extraction of aquatic animal tissues producing a dehydrated residue
US20030113432A1 (en) * 1998-11-02 2003-06-19 Nippon Suisan Kaisha, Ltd. Process for making dried powdery and granular krill
JP4229297B2 (ja) 1998-11-02 2009-02-25 日本水産株式会社 オキアミ乾燥粉粒体
AU2845400A (en) 1998-12-24 2000-07-31 Phairson Medical Inc. Treatment and prevention of immune rejection reactions
IT1315252B1 (it) 1999-10-21 2003-02-03 Truffini & Regge Farmaceutici Compresse gastroresistenti ad uso alimentare o dietetico ottenutemediante grassi miscelati alla massa
JP2001158736A (ja) 1999-11-30 2001-06-12 Snow Brand Milk Prod Co Ltd 骨関節疾患の予防及び改善剤
GB2358862B (en) 1999-12-21 2004-07-21 Fermentron Ltd Processes for Extracting Carotenoids from Biomass Carotenoid Sources
ATE395835T1 (de) 2000-04-12 2008-06-15 Westfalia Separator Gmbh Verfahren zur fraktionierung von öl- und polar lipid-enthaltenden rohstoffen
ES2752800T3 (es) 2000-05-01 2020-04-06 Cerecin Inc Uso de triglicéridos de cadena media para el tratamiento y la prevención de la enfermedad del Parkinson resultante de un metabolismo neuronal reducido
WO2002034850A1 (fr) * 2000-10-20 2002-05-02 Nippon Kayaku Kabushiki Kaisha Vernis contenant une resine polyamide et son utilisation
IL142535A0 (en) 2001-04-11 2002-03-10 Yeda Res & Dev Pharmaceutical compositions for the treatment of inflammation
JP3081692U (ja) 2001-05-11 2001-11-16 鶴進 陳 洗剤具備のシャワーロッド構造
EP1392623A4 (en) 2001-05-14 2005-05-04 Martek Biosciences Corp PREPARATION AND USE OF A POLAR LIPID RICH FRACTION CONTAINING HIGHLY UNSATURATED OMEGA-3 AND / OR OMEGA-6 FATTY ACIDS FROM MICROBES, SEEDS OF GENETICALLY MODIFIED PLANTS AND MARINE ORGANISMS
US20040241249A1 (en) 2001-06-18 2004-12-02 Tina Sampalis Krill and/or marine extracts for prevention and/or treatment of cardiovascular diseases arthritis, skin cancer diabetes, premenstrual syndrome and transdermal transport
JP2003003192A (ja) 2001-06-20 2003-01-08 Unitika Ltd スフィンゴ脂質又はスフィンゴ糖脂質の抽出方法
AR034680A1 (es) 2001-07-04 2004-03-03 Angulas Aguinaga S A Procedimiento para la obtencion de productos termoconformados a partir de las fracciones liquida y densa del krill antartico
DK1417211T3 (da) 2001-07-27 2007-10-08 Neptune Technologies & Bioress Naturlige phospholipider af marin oprindelse, der indeholder flavonoider og polyumættede phospholipider, og deres anvendelse
JP2003048831A (ja) 2001-08-02 2003-02-21 Suntory Ltd 脳機能の低下に起因する症状あるいは疾患の予防又は改善作用を有する組成物
JP4568464B2 (ja) 2001-11-07 2010-10-27 雪印乳業株式会社 記憶障害予防治療剤
US20050014722A1 (en) * 2001-12-13 2005-01-20 Gil-Ja Jhon Process for preparing n-acylated lysophosphatidylcholine and pharmaceutical composition for treatment of metabolic bone disease comprising said compounds
KR101195574B1 (ko) 2002-09-24 2012-10-30 산토리 홀딩스 가부시키가이샤 아라키돈산을 단독으로 또는 도코사헥사엔산과의 조합으로함유하는 인지 능력 향상용 조성물
US20060128665A1 (en) 2002-11-26 2006-06-15 Phares Pharmaceutical Research N.V. Marine lipid compositions
US7488503B1 (en) 2003-03-31 2009-02-10 Mccormick & Company, Inc. Encapsulation compositions and processes for preparing the same
CN1771046A (zh) * 2003-04-11 2006-05-10 协和发酵工业株式会社 关节炎的预防或治疗剂
GB0311081D0 (en) 2003-05-14 2003-06-18 Btg Internat Limted Treatment of neurodegenerative conditions
EP1633335A4 (en) 2003-06-19 2009-08-19 Advanced Bionutrition Corp IMPROVED ABSORPTION OF FAT-SOLUBLE NUTRIENTS
CN1816998B (zh) 2003-07-03 2010-06-02 皇家飞利浦电子股份有限公司 安全间接寻址
NO20033198D0 (no) 2003-07-15 2003-07-15 Norway Seafoods As Anordning ved trål
EP2324828A1 (en) 2003-08-18 2011-05-25 BTG International Limited Treatment for neurodegenerative conditions
IL158552A0 (en) 2003-10-22 2004-05-12 Enzymotec Ltd Lipids containing omega-3 fatty acids
IL158553A0 (en) 2003-10-22 2004-05-12 Enzymotec Ltd Method for preparing phosphatidylserine containing omega-3 acid moieties
ITMI20040069A1 (it) 2004-01-21 2004-04-21 Tiberio Bruzzese Uso di composizioni di acidi grassi n-3 ad elevata concentrazione per il trattamento di disturbi del sistema nervoso centrale
JP2005245379A (ja) 2004-03-08 2005-09-15 Nippon Suisan Kaisha Ltd 甲殻類の眼球の集合物、使用方法、含有する食品および製造方法
JP2006069948A (ja) 2004-09-01 2006-03-16 Yukihiro Hirose 老化防止組成物およびそれを含有する化粧料ならびに飲食品
JP2006083136A (ja) 2004-09-17 2006-03-30 Suntory Ltd ストレスに起因する脳機能の低下およびそれに伴う症状あるいは疾患の予防又は改善作用を有する組成物
US7666447B2 (en) 2004-10-08 2010-02-23 Pharmanutrients Compositions including Krill extracts and conjugated linoleic acid and methods of using same
US20060088574A1 (en) * 2004-10-25 2006-04-27 Manning Paul B Nutritional supplements
AU2005305610A1 (en) * 2004-11-17 2006-05-26 Natural Asa Enzymatically synthesized marine phospholipids
JP2006290784A (ja) 2005-04-08 2006-10-26 Yukihiro Hirose 血流悪化防止作用を有する組成物、及びそれを含有する飲食品
CA2606255C (fr) 2005-04-18 2013-10-08 Sc Dicophar Utilisation de la lecithine comme medicament dans le traitement du psoriasis
JP2006328014A (ja) 2005-05-30 2006-12-07 Yukihiro Hirose 血流悪化防止作用を有する組成物
JP2007246404A (ja) 2006-03-14 2007-09-27 Snow Brand Milk Prod Co Ltd 学習能向上剤
JP2007126455A (ja) 2005-10-07 2007-05-24 Fuji Chem Ind Co Ltd 脳機能障害の改善剤
AR059012A1 (es) 2006-01-13 2008-03-05 Aker Biomarine Asa Extractos derivados del krill
WO2007080514A2 (en) 2006-01-13 2007-07-19 Krill A/S A method for the extraction of lipid fractions from krill
NO20061315L (no) 2006-03-23 2007-09-24 Aker Seafoods Holding As Anordning ved tral
WO2007123424A1 (en) 2006-04-20 2007-11-01 Owen John Catchpole Process for separating lipid materials
NZ547429A (en) 2006-05-24 2009-09-25 Ind Res Ltd Extraction of highly unsaturated lipids with liquid dimethyl ether
PL2046312T3 (pl) 2006-07-14 2021-02-08 Kaydence Pharma As Produkty farmaceutyczne i nutraceutyki zawierające witaminę K2
AU2007320183B2 (en) 2006-11-16 2013-06-06 Pronova Biopharma Norge As Process for production of omega-3 rich marine phospholipids from krill
EP2095722A4 (en) 2006-12-11 2013-02-20 Nippon Suisan Kaisha Ltd FODDER OF HARVESTING KRILL AS AN EXISTING MATERIAL AND METHOD FOR PREVENTING FISH GROWTH DECLINE THEREOF
US20080166420A1 (en) 2007-01-04 2008-07-10 Sones Scott F Krill Oil Compositions
US20080166419A1 (en) 2007-01-04 2008-07-10 Sones Scott F Krill oil compositions
PL2144618T5 (pl) 2007-03-28 2025-07-21 Aker Biomarine Human Ingredients As Bio-skuteczne kompozycje oleju z kryla
US8697138B2 (en) 2007-03-28 2014-04-15 Aker Biomarine As Methods of using krill oil to treat risk factors for cardiovascular, metabolic, and inflammatory disorders
US20080268117A1 (en) 2007-04-30 2008-10-30 David Rubin Method of purifying oils containing epa and dha
US20100226977A1 (en) 2007-08-29 2010-09-09 Aker Biomarine Asa Low viscosity phospholipid compositions
US20090061067A1 (en) 2007-08-29 2009-03-05 Aker Biomarine Asa Method for making krill meal
CA2724463C (en) 2008-05-15 2017-10-03 Pronova Biopharma Norge As Krill oil process
US8557297B2 (en) 2008-09-12 2013-10-15 Olympic Seafood, As Method for processing crustaceans and products thereof
US8372812B2 (en) 2009-02-26 2013-02-12 Aker Biomarine Asa Phospholipid and protein tablets
WO2010097701A1 (en) 2009-02-26 2010-09-02 Aker Biomarine Asa Low viscosity phospholipid compositions
EP3335713B1 (en) 2009-10-29 2022-08-31 Acasti Pharma, Inc. Concentrated therapeutic phospholipid compositions
NZ599618A (en) 2009-10-30 2014-08-29 Tharos Ltd Solvent-free process for obtaining phospholipids and neutral enriched krill oils
US20110223246A1 (en) 2010-03-10 2011-09-15 Joar Opheim Docosahexaenoic acid bound in phospholipids and method of recovering same from a natural source
US9301982B2 (en) 2010-04-14 2016-04-05 Ganeden Biotech, Inc. Probiotic confection and lipid compositions
KR101875609B1 (ko) 2010-09-26 2018-08-02 엘지전자 주식회사 다중 안테나 지원 무선 통신 시스템에서 효율적인 피드백 방법 및 장치
SI2697345T1 (sl) 2011-04-14 2016-08-31 Polar Omega A/S Proces za izolacijo fosfolipida
EP2825057B8 (en) 2012-03-12 2020-06-24 Innolipid As Oxidixable fatty acid composition delivery form
AU2013291680C9 (en) 2012-07-17 2017-10-19 Aker Biomarine Antarctic As Concentration of omega-3 polyunsaturated fatty acids in krill oil
CN102746941B (zh) 2012-07-18 2014-01-15 山东师范大学 一种从南极磷虾中富集磷脂酰肌醇的方法
WO2014045127A2 (en) 2012-09-19 2014-03-27 Aker Biomarine As Omega-3 phospholipid supplements for females
WO2014057362A2 (en) 2012-09-24 2014-04-17 Aker Biopharma As Omega -3 compositions
US20140088047A1 (en) 2012-09-24 2014-03-27 Aker Bioassist As Use of long chain polyunsaturated fatty acid derivatives to treat sickle cell disease
WO2014140873A2 (en) 2013-03-14 2014-09-18 Aker Biomarine As Omega- 3 phospholipid supplements for improved brain maturity
AU2014203179C1 (en) 2013-06-14 2017-05-04 Aker Biomarine Antarctic As Lipid extraction processes

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