PL2178568T3 - Środki cieniujące - Google Patents

Środki cieniujące

Info

Publication number
PL2178568T3
PL2178568T3 PL08793873T PL08793873T PL2178568T3 PL 2178568 T3 PL2178568 T3 PL 2178568T3 PL 08793873 T PL08793873 T PL 08793873T PL 08793873 T PL08793873 T PL 08793873T PL 2178568 T3 PL2178568 T3 PL 2178568T3
Authority
PL
Poland
Prior art keywords
contrast agents
agents
contrast
Prior art date
Application number
PL08793873T
Other languages
English (en)
Inventor
Mikkel Thaning
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Publication of PL2178568T3 publication Critical patent/PL2178568T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0452—Solutions, e.g. for injection

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Steroid Compounds (AREA)
PL08793873T 2007-07-12 2008-07-04 Środki cieniujące PL2178568T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
NO20073594 2007-07-12
NO20073595 2007-07-12
PCT/NO2008/000255 WO2009008734A2 (en) 2007-07-12 2008-07-04 Contrast agents
EP08793873.4A EP2178568B1 (en) 2007-07-12 2008-07-04 Contrast agents

Publications (1)

Publication Number Publication Date
PL2178568T3 true PL2178568T3 (pl) 2014-09-30

Family

ID=39811676

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08793873T PL2178568T3 (pl) 2007-07-12 2008-07-04 Środki cieniujące

Country Status (18)

Country Link
US (2) US8920780B2 (pl)
EP (1) EP2178568B1 (pl)
JP (3) JP5340281B2 (pl)
KR (2) KR20100033405A (pl)
CN (4) CN103951586B (pl)
AU (1) AU2008273037B2 (pl)
BR (1) BRPI0814811A2 (pl)
CA (1) CA2692646C (pl)
CO (1) CO6351754A2 (pl)
DK (1) DK2178568T3 (pl)
ES (1) ES2486296T3 (pl)
HR (1) HRP20140649T1 (pl)
IL (1) IL202487A (pl)
NZ (1) NZ581765A (pl)
PL (1) PL2178568T3 (pl)
PT (1) PT2178568E (pl)
RU (1) RU2469021C2 (pl)
WO (1) WO2009008734A2 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103951586B (zh) * 2007-07-12 2015-05-27 通用电气医疗集团股份有限公司 造影剂
EP2385845A1 (en) * 2009-01-09 2011-11-16 Ge Healthcare As Contrast media compositions
DK2493511T3 (da) * 2009-10-29 2013-11-25 Ge Healthcare As Diagnostisk sammensætning omfattende plasmakationer som har en forbedret sikkerhedsprofil
KR101915821B1 (ko) * 2010-03-23 2018-11-06 지이 헬스케어 에이에스 안정화된 ｘ―선 진단용 조성물의 제조
JP2013531685A (ja) 2010-07-12 2013-08-08 ジーイー・ヘルスケア・アクスイェ・セルスカプ 低造影剤濃度及び／又は低放射線量でのｘ線イメージング
ES2680019T3 (es) 2010-12-21 2018-09-03 Ge Healthcare As Desalinización de una composición que comprende un agente de contraste
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
AU2012311584B2 (en) * 2011-09-21 2017-04-20 Ge Healthcare As Packaging of contrast media
GB2496971A (en) * 2011-11-25 2013-05-29 Ge Healthcare As Preparation of X-ray contrast agents
NO333914B1 (no) * 2011-12-21 2013-10-21 Ge Healthcare As Stabilisering av diagnostisk røntgensammensetning
MX2014008517A (es) 2012-01-11 2014-08-21 Ge Healthcare As Medio de contraste de formacion de imagenes de rayos x con concentracion baja de yodo y proceso para formacion de imagenes de rayos x.
CN110003038A (zh) 2012-09-27 2019-07-12 通用电气医疗集团股份有限公司 Ioforminol的中间体化合物的制备
RU2642436C2 (ru) * 2012-09-27 2018-01-25 ДжиИ Хелткер АС Получение иоформинола - рентгеноконтрастного агента
PT2917174T (pt) * 2012-11-12 2018-11-14 Ge Healthcare As Preparação de intermediários de agentes de contraste de raios-x
CA2890449C (en) * 2012-12-19 2020-12-29 Ge Healthcare As Purification of x-ray contrast agents
KR20150134346A (ko) 2013-03-27 2015-12-01 지이 헬스케어 에이에스 진단 조성물을 제조하기 위한 방법 및 시약
US9695113B2 (en) * 2013-12-06 2017-07-04 Ge Healthcare As Alternative process for the purification of an intermediate in the synthesis of non-ionic X-ray contrast agents
CN105017063B (zh) * 2014-04-18 2018-11-20 沈阳中海生物技术开发有限公司 5-氨基-2,4,6-三碘间苯二甲酸衍生物及其盐、水合物或溶剂化物
CN108341750B (zh) * 2017-01-21 2020-10-23 浙江海洲制药有限公司 一种制备碘化造影剂中间体时所产生的杂质的合成方法
CN114560775B (zh) * 2022-03-17 2023-08-22 绵阳师范学院 (r,s)-7-氟-1,1,3-三甲基-2,3-二氢-1h-茚-4-胺的制备方法
EP4704924A1 (en) 2023-04-23 2026-03-11 Translational And Fundamental Technologies Institute Llc Radionuclide-loaded nanoparticles for focal tissue ablation

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SE344166B (pl) 1966-12-13 1972-04-04 Pharmacia Ab
US3804892A (en) 1967-12-28 1974-04-16 Pharmacia Ab Novel 3,5-substituted 2,4,6-triiodobenzoic acids and salts thereof
SE315974B (pl) * 1967-12-28 1969-10-13 Pharmacia Ab
US3763227A (en) 1967-12-28 1973-10-02 Pharmacia Ab Novel 3,5-substituted 2,4,6-triiodobenzoic acids and salts thereof
DE2628517C2 (de) 1976-06-23 1985-02-21 Schering AG, 1000 Berlin und 4709 Bergkamen Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel
IT1207226B (it) 1979-08-09 1989-05-17 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
DE3038853A1 (de) 1980-10-10 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii)
ATE20733T1 (de) * 1982-11-08 1986-08-15 Nyegaard & Co As Roentgenkontrastmittel.
EP0365541B1 (en) * 1987-05-22 1992-08-12 BRACCO S.p.A. Preparation of 5-acylamino-2,4,6-triiodo- or tribromo-benzoic acid derivatives
FR2634571B1 (fr) 1988-07-19 1990-10-19 Kodak Pathe Procede d'organisation et de lecture d'un support magnetique et support en faisant application
IL94718A (en) * 1989-07-05 1994-10-21 Schering Ag Carboxamide non-ionic contrast media and method for the preparation thereof
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IT1245853B (it) 1990-11-16 1994-10-25 Bracco Spa 1,3-bis(3-(mono o poliidrossi)acilamino-5-(mono o poliidrossi-alchil) aminocarbonil-2,4,6-triiodo-benzoil-amino)-idrossi- o idrossi-alchil- propani, loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono
JPH08506808A (ja) 1992-12-21 1996-07-23 ザ、プロクター、エンド、ギャンブル、カンパニー 呼吸障害治療用組成物の製造における鎮痛剤ｓ（＋）対掌体の利用
IT1256248B (it) * 1992-12-24 1995-11-29 Bracco Spa Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x
GB9303992D0 (en) 1993-02-26 1993-04-14 Nycomed Imaging As Contrast agents
WO1994022810A1 (es) 1993-04-01 1994-10-13 Centro Investigacion Justesa Imagen, S.A. Nuevos dimeros iodados no ionicos como agentes de contraste a los rayos x, metodo para su preparacion y composiciones galenicas que los contienen
GB9419203D0 (en) * 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
CN1164225A (zh) * 1994-09-23 1997-11-05 尼科梅德成像有限公司 碘代x-射线造影剂
WO1997000240A1 (en) 1995-06-16 1997-01-03 Biophysica Foundation Formyl derivatives as nonionic contrast media
US6072069A (en) 1998-11-04 2000-06-06 Biophysica, Inc. Biodegradable nonionic contrast media
GB9903109D0 (en) * 1999-02-11 1999-04-07 Nycomed Imaging As Process
EP1186305A1 (en) 2000-09-07 2002-03-13 Schering Aktiengesellschaft New brominated compounds as contrast media for X-ray mammography
DE60324401D1 (de) 2002-03-27 2008-12-11 Fujifilm Corp Iodierte triglycerid-derivate
JP4096908B2 (ja) * 2004-03-31 2008-06-04 株式会社豊田自動織機 回転電機の製造方法
US20050281746A1 (en) * 2004-06-16 2005-12-22 Melton Laura J Anticoagulant contrast media
CN103951586B (zh) 2007-07-12 2015-05-27 通用电气医疗集团股份有限公司 造影剂
JP6723006B2 (ja) 2015-12-10 2020-07-15 株式会社オカムラ 椅子

Also Published As

Publication number Publication date
RU2469021C2 (ru) 2012-12-10
CA2692646C (en) 2014-09-09
DK2178568T3 (da) 2014-07-21
KR101555457B1 (ko) 2015-09-23
BRPI0814811A2 (pt) 2015-02-03
EP2178568A2 (en) 2010-04-28
IL202487A (en) 2015-06-30
JP2013151533A (ja) 2013-08-08
IL202487A0 (en) 2010-06-30
WO2009008734A3 (en) 2009-10-29
WO2009008734A2 (en) 2009-01-15
JP5628363B2 (ja) 2014-11-19
US9738596B2 (en) 2017-08-22
JP2010533172A (ja) 2010-10-21
CO6351754A2 (es) 2011-12-20
CA2692646A1 (en) 2009-01-15
US8920780B2 (en) 2014-12-30
AU2008273037B2 (en) 2012-11-15
PT2178568E (pt) 2014-08-25
US20100322868A1 (en) 2010-12-23
CN103951586A (zh) 2014-07-30
JP2015007084A (ja) 2015-01-15
RU2009148141A (ru) 2011-08-20
KR20100033405A (ko) 2010-03-29
KR20140111350A (ko) 2014-09-18
CN101687051A (zh) 2010-03-31
AU2008273037A1 (en) 2009-01-15
NZ581765A (en) 2012-03-30
ES2486296T3 (es) 2014-08-18
JP5340281B2 (ja) 2013-11-13
JP5830589B2 (ja) 2015-12-09
HRP20140649T1 (hr) 2014-09-26
CN103980154A (zh) 2014-08-13
US20150191422A1 (en) 2015-07-09
CN103951586B (zh) 2015-05-27
CN103980154B (zh) 2015-02-25
EP2178568B1 (en) 2014-07-02
CN103951585A (zh) 2014-07-30

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