PL2182948T3 - Zastosowanie imidazochinolin do leczenia chorób EGFR-zależnych albo chorób wykazujących nabytą oporność wobec środków ukierunkowanych na członków rodziny EGFR - Google Patents

Zastosowanie imidazochinolin do leczenia chorób EGFR-zależnych albo chorób wykazujących nabytą oporność wobec środków ukierunkowanych na członków rodziny EGFR

Info

Publication number
PL2182948T3
PL2182948T3 PL08786340T PL08786340T PL2182948T3 PL 2182948 T3 PL2182948 T3 PL 2182948T3 PL 08786340 T PL08786340 T PL 08786340T PL 08786340 T PL08786340 T PL 08786340T PL 2182948 T3 PL2182948 T3 PL 2182948T3
Authority
PL
Poland
Prior art keywords
diseases
egfr
imidazoquinolines
agents
treatment
Prior art date
Application number
PL08786340T
Other languages
English (en)
Inventor
Carlos Garcia-Echeverria
Sauveur-Michel Maira
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL2182948T3 publication Critical patent/PL2182948T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL08786340T 2007-07-24 2008-07-23 Zastosowanie imidazochinolin do leczenia chorób EGFR-zależnych albo chorób wykazujących nabytą oporność wobec środków ukierunkowanych na członków rodziny EGFR PL2182948T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07112998 2007-07-24
PCT/EP2008/059642 WO2009013305A1 (en) 2007-07-24 2008-07-23 Use of imidazoquinolines for the treatment of egfr dependent diseases or diseases that have acquired resistance to agents that target egfr family members
EP08786340A EP2182948B1 (en) 2007-07-24 2008-07-23 Use of imidazoquinolines for the treatment of egfr dependent diseases or diseases that have acquired resistance to agents that target egfr family members

Publications (1)

Publication Number Publication Date
PL2182948T3 true PL2182948T3 (pl) 2013-07-31

Family

ID=38779856

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08786340T PL2182948T3 (pl) 2007-07-24 2008-07-23 Zastosowanie imidazochinolin do leczenia chorób EGFR-zależnych albo chorób wykazujących nabytą oporność wobec środków ukierunkowanych na członków rodziny EGFR

Country Status (13)

Country Link
US (1) US20100196365A1 (pl)
EP (1) EP2182948B1 (pl)
JP (1) JP2010534219A (pl)
KR (1) KR20100039354A (pl)
CN (1) CN103298471A (pl)
AU (1) AU2008280105B2 (pl)
BR (1) BRPI0814346A2 (pl)
CA (1) CA2693799A1 (pl)
ES (1) ES2401822T3 (pl)
PL (1) PL2182948T3 (pl)
PT (1) PT2182948E (pl)
RU (2) RU2481838C2 (pl)
WO (1) WO2009013305A1 (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110033453A1 (en) * 2008-03-05 2011-02-10 Carlos Garcia-Echeverria Use of pyrimidine derivatives for the treatment of egfr dependent diseases or diseases that have acquired resistance to agents that target egfr family members
GEP20156267B (en) * 2009-06-04 2015-04-14 Novartis Ag 1H-IMIDAZO[4,5-c]QUINOLINONE DERIVATIVES
CA2851383A1 (en) * 2011-10-14 2013-04-18 Xizhong Huang 2 - carboxamide cycloamino urea derivatives in combination with hsp90 inhibitors for the treatment of proliferative diseases
TW201703769A (zh) * 2015-05-08 2017-02-01 美國禮來大藥廠 用於癌症的組合療法
EP3297629A1 (en) 2015-05-20 2018-03-28 Novartis AG Pharmaceutical combination of everolimus with dactolisib
BR112019010470A2 (pt) 2016-11-23 2019-09-10 Novartis Ag métodos de realce de resposta imune com everolimo, dactolisib ou ambos
US10596165B2 (en) 2018-02-12 2020-03-24 resTORbio, Inc. Combination therapies
KR102871791B1 (ko) 2018-09-10 2025-10-15 미라티 테라퓨틱스, 인크. 병용 요법
CN110812479A (zh) * 2019-11-18 2020-02-21 青海晨菲制药有限公司 没食子酸和egfr靶点抗体组合物及其在肺癌上应用
CN115354079A (zh) * 2022-09-05 2022-11-18 复旦大学附属中山医院 一种用于检测egfr靶向药物治疗适用性的试剂盒

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR046845A1 (es) * 2003-11-21 2005-12-28 Novartis Ag Derivados de 1h-imidazo[4,5-c]quinolina para tratamiento de enfermedades dependientes de las proteino-quinasas
HRP20141111T1 (hr) * 2004-07-22 2015-01-02 Genentech, Inc. Sastav her2-protutijela
GB0510390D0 (en) * 2005-05-20 2005-06-29 Novartis Ag Organic compounds
US20110033453A1 (en) * 2008-03-05 2011-02-10 Carlos Garcia-Echeverria Use of pyrimidine derivatives for the treatment of egfr dependent diseases or diseases that have acquired resistance to agents that target egfr family members

Also Published As

Publication number Publication date
EP2182948B1 (en) 2013-03-06
RU2481838C2 (ru) 2013-05-20
WO2009013305A1 (en) 2009-01-29
KR20100039354A (ko) 2010-04-15
PT2182948E (pt) 2013-04-30
RU2010106241A (ru) 2011-08-27
AU2008280105A1 (en) 2009-01-29
BRPI0814346A2 (pt) 2015-01-20
US20100196365A1 (en) 2010-08-05
AU2008280105B2 (en) 2011-10-20
JP2010534219A (ja) 2010-11-04
ES2401822T3 (es) 2013-04-24
CN103298471A (zh) 2013-09-11
CA2693799A1 (en) 2009-01-29
RU2012151889A (ru) 2014-06-10
EP2182948A1 (en) 2010-05-12

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