PL2195311T3 - Pochodne pirydynowe jako modulatory receptora S1P1/EDG1 - Google Patents

Pochodne pirydynowe jako modulatory receptora S1P1/EDG1

Info

Publication number: PL2195311T3
Authority: PL; Poland
Prior art keywords: receptor modulators; pyridine derivatives; edg1 receptor; edg1; pyridine
Prior art date: 2007-08-17

Application number

PL08789611T

Other languages

English (en)

Inventor

Martin Bolli

Cyrille Lescop

Boris Mathys

Claus Mueller

Oliver Nayler

Beat Steiner

Jörg Velker

Original Assignee

Actelion Pharmaceuticals Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-08-17

Filing date

2008-08-14

Publication date

2011-08-31

2008-08-14 Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd

2011-08-31 Publication of PL2195311T3 publication Critical patent/PL2195311T3/pl

Links

101000693265 Homo sapiens Sphingosine 1-phosphate receptor 1 Proteins 0.000 title 1
102100025750 Sphingosine 1-phosphate receptor 1 Human genes 0.000 title 1
150000003222 pyridines Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Endocrinology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Oncology (AREA)
Otolaryngology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Obesity (AREA)
Transplantation (AREA)
Psychiatry (AREA)
Ophthalmology & Optometry (AREA)
Emergency Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)

PL08789611T 2007-08-17 2008-08-14 Pochodne pirydynowe jako modulatory receptora S1P1/EDG1 PL2195311T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
IB2007053293		2007-08-17
EP08789611A EP2195311B1 (en)	2007-08-17	2008-08-14	Pyridine derivatives as s1p1/edg1 receptor modulators
PCT/IB2008/053269 WO2009024905A1 (en)	2007-08-17	2008-08-14	Pyridine derivatives as s1p1/edg1 receptor modulators

Publications (1)

Publication Number	Publication Date
PL2195311T3 true PL2195311T3 (pl)	2011-08-31

Family

ID=40193868

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL08789611T PL2195311T3 (pl)	2007-08-17	2008-08-14	Pochodne pirydynowe jako modulatory receptora S1P1/EDG1

Country Status (26)

Country	Link
US (1)	US8598208B2 (pl)
EP (1)	EP2195311B1 (pl)
JP (1)	JP5451614B2 (pl)
KR (1)	KR101541558B1 (pl)
CN (1)	CN102648198B (pl)
AR (1)	AR067977A1 (pl)
AT (1)	ATE502938T1 (pl)
AU (1)	AU2008290233B2 (pl)
BR (1)	BRPI0815190A2 (pl)
CA (1)	CA2695509A1 (pl)
CY (1)	CY1111830T1 (pl)
DE (1)	DE602008005770D1 (pl)
DK (1)	DK2195311T3 (pl)
ES (1)	ES2361463T3 (pl)
HR (1)	HRP20110449T1 (pl)
MA (1)	MA31703B1 (pl)
MX (1)	MX2010001881A (pl)
MY (1)	MY153975A (pl)
NZ (1)	NZ583957A (pl)
PL (1)	PL2195311T3 (pl)
PT (1)	PT2195311E (pl)
RU (1)	RU2492168C2 (pl)
SI (1)	SI2195311T1 (pl)
TW (1)	TWI422373B (pl)
WO (1)	WO2009024905A1 (pl)
ZA (1)	ZA201001873B (pl)

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SMT202000298T1 (it)	2012-08-17	2020-07-08	Actelion Pharmaceuticals Ltd	Processo per la produzione di (2z,5z)-5-(3-cloro-4((r)-2,3-diidrossipropossi) benziliden)-2-(propilimmino)-3-(o-tolil)tiazolidin-4-one e intermedio usato in detto processo
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US10111841B2 (en)	2015-06-19	2018-10-30	University Of South Florida	Stabilization of alcohol intoxication-induced cardiovascular instability
WO2017004609A1 (en)	2015-07-02	2017-01-05	Exelixis, Inc.	Thiadiazole modulators of s1p and methods of making and using
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EA201891644A1 (ru)	2016-03-07	2019-04-30	Зе Глобал Эллайенс Фо Тб Драг Девелопмент, Инк.	Антибактериальные соединения и их применение
JP2019513700A (ja)	2016-03-16	2019-05-30	バイエル・クロップサイエンス・アクチェンゲゼルシャフト	殺有害生物剤及び植物保護剤としてのｎ−（シアノベンジル）−６−（シクロプロピル−カルボニルアミノ）−４−（フェニル）−ピリジン−２−カルボキサミド誘導体及び関連する化合物
US11014940B1 (en)	2018-10-16	2021-05-25	Celgene Corporation	Thiazolidinone and oxazolidinone compounds and formulations
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US11014897B1 (en)	2018-10-16	2021-05-25	Celgene Corporation	Solid forms comprising a thiazolidinone compound, compositions and methods of use thereof
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SI2069335T1 (sl)	2006-09-08	2013-04-30	Actelion Pharmaceuticals Ltd.	Derivati piridin-3-ila kot imunomodulacijska sredstva
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JP2010521450A (ja)	2007-03-16	2010-06-24	アクテリオンファーマシューティカルズリミテッド	Ｓ１ｐ１／ｅｄｇ１受容体アゴニストとしてのアミノ−ピリジン誘導体
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CA2714614A1 (en)	2008-03-06	2009-09-11	Actelion Pharmaceuticals Ltd	Novel pyrimidine-pyridine derivatives
EP2262799B1 (en)	2008-03-06	2012-07-04	Actelion Pharmaceuticals Ltd.	Pyridine compounds
SI2252609T1 (sl)	2008-03-07	2013-07-31	Actelion Pharmaceuticals Ltd.	Derivati piridin-2-ila kot imunomodulacijska sredstva
BRPI0910288A2 (pt)	2008-03-07	2019-09-24	Actelion Pharmaceuticals Ltd	composto de derivados de aminometil benzeno, composição farmacêutica que compreende esse composto e uso do mesmo.
HUE025984T2 (hu)	2008-05-14	2016-05-30	Scripps Research Inst	Szfingozin foszfát receptor új modulátorai
KR101409131B1 (ko)	2009-07-16	2014-06-17	액테리온 파마슈티칼 리미티드	피리딘-4-일 유도체

2008
- 2008-08-14 PL PL08789611T patent/PL2195311T3/pl unknown
- 2008-08-14 AU AU2008290233A patent/AU2008290233B2/en not_active Ceased
- 2008-08-14 HR HR20110449T patent/HRP20110449T1/hr unknown
- 2008-08-14 PT PT08789611T patent/PT2195311E/pt unknown
- 2008-08-14 DE DE602008005770T patent/DE602008005770D1/de active Active
- 2008-08-14 WO PCT/IB2008/053269 patent/WO2009024905A1/en not_active Ceased
- 2008-08-14 ES ES08789611T patent/ES2361463T3/es active Active
- 2008-08-14 BR BRPI0815190 patent/BRPI0815190A2/pt not_active IP Right Cessation
- 2008-08-14 MY MYPI2010000684A patent/MY153975A/en unknown
- 2008-08-14 SI SI200830269T patent/SI2195311T1/sl unknown
- 2008-08-14 JP JP2010520670A patent/JP5451614B2/ja not_active Expired - Fee Related
- 2008-08-14 NZ NZ583957A patent/NZ583957A/en not_active IP Right Cessation
- 2008-08-14 US US12/673,918 patent/US8598208B2/en not_active Expired - Fee Related
- 2008-08-14 DK DK08789611.4T patent/DK2195311T3/da active
- 2008-08-14 MX MX2010001881A patent/MX2010001881A/es active IP Right Grant
- 2008-08-14 CA CA2695509A patent/CA2695509A1/en not_active Abandoned
- 2008-08-14 KR KR1020107005759A patent/KR101541558B1/ko not_active Expired - Fee Related
- 2008-08-14 CN CN200880103070.2A patent/CN102648198B/zh not_active Expired - Fee Related
- 2008-08-14 EP EP08789611A patent/EP2195311B1/en not_active Not-in-force
- 2008-08-14 RU RU2010109542/04A patent/RU2492168C2/ru not_active IP Right Cessation
- 2008-08-14 AT AT08789611T patent/ATE502938T1/de active
- 2008-08-15 TW TW097131346A patent/TWI422373B/zh not_active IP Right Cessation
- 2008-08-19 AR ARP080103611A patent/AR067977A1/es not_active Application Discontinuation
2010
- 2010-03-12 MA MA32693A patent/MA31703B1/fr unknown
- 2010-03-16 ZA ZA2010/01873A patent/ZA201001873B/en unknown
2011
- 2011-05-30 CY CY20111100521T patent/CY1111830T1/el unknown

Also Published As

Publication number	Publication date
EP2195311B1 (en)	2011-03-23
AR067977A1 (es)	2009-10-28
CA2695509A1 (en)	2009-02-26
US20110212998A1 (en)	2011-09-01
HRP20110449T1 (hr)	2011-07-31
TW200918055A (en)	2009-05-01
ZA201001873B (en)	2012-05-30
MA31703B1 (fr)	2010-09-01
ATE502938T1 (de)	2011-04-15
CY1111830T1 (el)	2015-10-07
TWI422373B (zh)	2014-01-11
NZ583957A (en)	2011-09-30
DE602008005770D1 (de)	2011-05-05
SI2195311T1 (sl)	2011-07-29
AU2008290233A1 (en)	2009-02-26
KR101541558B1 (ko)	2015-08-03
CN102648198A (zh)	2012-08-22
RU2010109542A (ru)	2011-09-27
MX2010001881A (es)	2010-03-10
JP5451614B2 (ja)	2014-03-26
EP2195311A1 (en)	2010-06-16
JP2010536741A (ja)	2010-12-02
ES2361463T3 (es)	2011-06-17
AU2008290233B2 (en)	2013-10-10
DK2195311T3 (da)	2011-05-23
BRPI0815190A2 (pt)	2015-03-31
CN102648198B (zh)	2015-04-01
PT2195311E (pt)	2011-05-25
US8598208B2 (en)	2013-12-03
RU2492168C2 (ru)	2013-09-10
KR20100058561A (ko)	2010-06-03
WO2009024905A1 (en)	2009-02-26
MY153975A (en)	2015-04-30
HK1144809A1 (en)	2011-03-11

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