PL2206698T3 - Związki etynyloindolowe - Google Patents

Związki etynyloindolowe

Info

Publication number
PL2206698T3
PL2206698T3 PL09180244T PL09180244T PL2206698T3 PL 2206698 T3 PL2206698 T3 PL 2206698T3 PL 09180244 T PL09180244 T PL 09180244T PL 09180244 T PL09180244 T PL 09180244T PL 2206698 T3 PL2206698 T3 PL 2206698T3
Authority
PL
Poland
Prior art keywords
ethynylindole
compounds
ethynylindole compounds
Prior art date
Application number
PL09180244T
Other languages
English (en)
Inventor
Ohmoto Kazuyuki
Itadani Satoshi
Nakayama Yoshisuke
Takeuchi Jun
Fujita Manabu
Original Assignee
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co
Publication of PL2206698T3 publication Critical patent/PL2206698T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
PL09180244T 2008-12-22 2009-12-21 Związki etynyloindolowe PL2206698T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2008325815 2008-12-22
EP09180244A EP2206698B1 (en) 2008-12-22 2009-12-21 Ethynylindole compounds

Publications (1)

Publication Number Publication Date
PL2206698T3 true PL2206698T3 (pl) 2012-12-31

Family

ID=42110130

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09180244T PL2206698T3 (pl) 2008-12-22 2009-12-21 Związki etynyloindolowe

Country Status (18)

Country Link
US (1) US8115014B2 (pl)
EP (1) EP2206698B1 (pl)
JP (2) JP5012884B2 (pl)
KR (1) KR101464778B1 (pl)
CN (1) CN101759628B (pl)
AU (1) AU2009250960C1 (pl)
BR (1) BRPI0905601A2 (pl)
CA (1) CA2688614C (pl)
DK (1) DK2206698T3 (pl)
ES (1) ES2387185T3 (pl)
IL (1) IL202869A (pl)
MX (1) MX2009013926A (pl)
NZ (1) NZ582208A (pl)
PL (1) PL2206698T3 (pl)
PT (1) PT2206698E (pl)
RU (1) RU2505531C2 (pl)
TW (1) TWI469965B (pl)
ZA (1) ZA200909096B (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY162757A (en) * 2010-06-21 2017-07-14 Ono Pharmaceutical Co New Crystalline Forms of 4,4’-[4-Fluoro-7-({4-[4-(3-Fluoro-2-Methylphenyl) Butoxy] Phenyl}Ethynyl)-2-Methyl-1H-Indole-1, 3-Diyl] Dibutanoic Acid
KR101171790B1 (ko) 2010-07-30 2012-08-13 현대자동차주식회사 인출식 자전거 캐리어
US9133168B2 (en) 2010-12-28 2015-09-15 Sanofi Pyrimidine derivatives, preparation thereof, and pharmaceutical use thereof as akt(pkb) phosphorylation inhibitors
EP2537866A1 (en) * 2011-06-21 2012-12-26 Serumwerk Bernburg AG Hydroxyethyl starch derivatives, method for manufacturing the same and therapeutical uses thereof
CN103893146A (zh) * 2012-12-25 2014-07-02 天津药物研究院 含福多司坦缓释剂型
US11427591B2 (en) * 2018-10-17 2022-08-30 Insilico Medicine Ip Limited Kinase inhibitors
US20230147364A1 (en) * 2020-04-30 2023-05-11 Kyoto University Prophylactic or therapeutic agent for rna virus-related diseases

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE555319A (pl) 1956-03-21 1900-01-01
US3095355A (en) 1961-10-12 1963-06-25 Revlon Aerosol composition
JPH01192476A (ja) 1988-01-25 1989-08-02 Kawasaki Steel Corp 溶接鋼管の製造方法
US5137910A (en) 1989-05-05 1992-08-11 C.D. Searle & Co. Compositions containing indole-2-carboxylate compounds for treatment of CNS disorders
JPH0347123A (ja) 1989-05-05 1991-02-28 G D Searle & Co インドール―2―カルボキシレート化合物類を含有するcns疾患治療用組成物
US5229413A (en) 1989-05-05 1993-07-20 G. D. Searle & Co. Compositions containing indole-2-carboxylate compounds for treatment of CNS disorders
CA2019335C (en) 1989-06-27 2000-08-01 Mitoshi Konno Phenylalkan (en)oic acids
GB9027018D0 (en) * 1990-12-12 1991-01-30 Ici Plc Heterocyclic compounds
WO1994022821A1 (en) 1993-04-05 1994-10-13 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives as testosterone 5 alpha-reductase inhibitors
WO1997013751A1 (en) 1995-10-10 1997-04-17 Pfizer Inc. Indole carbamates as leukotriene antagonists
FR2766824B1 (fr) 1997-07-30 1999-09-10 Adir Nouveaux composes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB9902455D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
AU2001270200A1 (en) 2000-06-27 2002-01-08 Smith Kline Beecham Corporation Fatty acid synthase inhibitors
JP2003025362A (ja) 2001-07-18 2003-01-29 Nippon Tokushu Toryo Co Ltd 通気性を有する発泡プラスチック及びその製法
US6867224B2 (en) 2002-03-07 2005-03-15 Warner-Lambert Company Compounds that modulate PPAR activity and methods of preparation
JP2005532280A (ja) 2002-04-03 2005-10-27 アストラゼネカ アクチボラグ 化合物
DE60328675D1 (de) 2002-04-23 2009-09-17 Aventis Pharma Inc 3-(substitutierte amino)-1h-indole-2-carbonsäureester und 3-(substitutierte amino)-benzoäbüthiophen-2-carbonsäureester verbindungen als inhibitoren der interleukin-4 genexpression
SE0202241D0 (sv) 2002-07-17 2002-07-17 Astrazeneca Ab Novel Compounds
US7329680B2 (en) 2003-04-30 2008-02-12 The Institute For Pharmaceutical Discovery, Llc Heterocycle substituted carboxylic acids
JP4720502B2 (ja) * 2003-09-01 2011-07-13 小野薬品工業株式会社 縮環化合物およびその用途
NZ560513A (en) * 2005-02-25 2010-07-30 Ono Pharmaceutical Co Indole compound and use thereof

Also Published As

Publication number Publication date
AU2009250960C1 (en) 2014-01-23
TW201026664A (en) 2010-07-16
EP2206698A1 (en) 2010-07-14
KR101464778B1 (ko) 2014-11-24
MX2009013926A (es) 2010-06-22
PT2206698E (pt) 2012-08-03
ES2387185T3 (es) 2012-09-17
RU2009147506A (ru) 2011-06-27
BRPI0905601A2 (pt) 2012-05-02
CA2688614A1 (en) 2010-06-22
CN101759628A (zh) 2010-06-30
TWI469965B (zh) 2015-01-21
CN101759628B (zh) 2013-02-27
AU2009250960B2 (en) 2013-09-05
US20100160647A1 (en) 2010-06-24
ZA200909096B (en) 2010-09-29
JP2010168359A (ja) 2010-08-05
AU2009250960A1 (en) 2010-07-08
EP2206698B1 (en) 2012-07-18
IL202869A (en) 2015-02-26
CA2688614C (en) 2015-01-06
US8115014B2 (en) 2012-02-14
JP5012884B2 (ja) 2012-08-29
NZ582208A (en) 2011-05-27
KR20100074036A (ko) 2010-07-01
JP2012144546A (ja) 2012-08-02
RU2505531C2 (ru) 2014-01-27
DK2206698T3 (da) 2012-08-27

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