PL2225271T3 - Nowe nieselektywne analogi somatostatyny - Google Patents

Nowe nieselektywne analogi somatostatyny

Info

Publication number: PL2225271T3
Authority: PL; Poland
Prior art keywords: new non; somatostatin analogues; selective somatostatin; selective; analogues
Prior art date: 2007-12-03

Application number

PL08856519T

Other languages

English (en)

Inventor

Andrea Vitali

Massimo Pinori

Paolo Mascagni

Original Assignee

Italfarmaco Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-12-03

Filing date

2008-11-24

Publication date

2013-12-31

2007-12-03 Priority claimed from ITMI20072266 external-priority patent/ITMI20072266A1/it

2007-12-07 Priority claimed from EP07425778A external-priority patent/EP2067786A1/en

2008-11-24 Application filed by Italfarmaco Spa filed Critical Italfarmaco Spa

2013-12-31 Publication of PL2225271T3 publication Critical patent/PL2225271T3/pl

Links

NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 title 1
229940075620 somatostatin analogue Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Immunology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Transplantation (AREA)
Vascular Medicine (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL08856519T 2007-12-03 2008-11-24 Nowe nieselektywne analogi somatostatyny PL2225271T3 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
ITMI20072266 ITMI20072266A1 (it)	2007-12-03	2007-12-03	Nuovi analoghi non selettivi di somatostatina
EP07425778A EP2067786A1 (en)	2007-12-07	2007-12-07	Novel non selective analogs of somatostatin
EP08856519.7A EP2225271B1 (en)	2007-12-03	2008-11-24	New non-selective somatostatin analogues
PCT/EP2008/066081 WO2009071460A2 (en)	2007-12-03	2008-11-24	New non-selective somatostatin analogues

Publications (1)

Publication Number	Publication Date
PL2225271T3 true PL2225271T3 (pl)	2013-12-31

Family

ID=40667736

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL08856519T PL2225271T3 (pl)	2007-12-03	2008-11-24	Nowe nieselektywne analogi somatostatyny

Country Status (15)

Country	Link
US (1)	US8937152B2 (pl)
EP (1)	EP2225271B1 (pl)
JP (1)	JP5331817B2 (pl)
KR (1)	KR101500528B1 (pl)
CN (1)	CN101883785B (pl)
BR (1)	BRPI0818978B8 (pl)
CA (1)	CA2702940C (pl)
CY (1)	CY1114490T1 (pl)
DK (1)	DK2225271T3 (pl)
ES (1)	ES2431573T3 (pl)
HR (1)	HRP20130948T1 (pl)
PL (1)	PL2225271T3 (pl)
PT (1)	PT2225271E (pl)
SI (1)	SI2225271T1 (pl)
WO (1)	WO2009071460A2 (pl)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2008232709C1 (en)	2007-03-28	2015-01-15	President And Fellows Of Harvard College	Stitched polypeptides
DK2225271T3 (da) *	2007-12-03	2013-10-07	Italfarmaco Spa	Nye ikke-selektive somatostatin-analoger
KR20170058446A (ko)	2010-08-13	2017-05-26	에일러론 테라퓨틱스 인코포레이티드	펩티도미메틱 거대고리
JP6211418B2 (ja) *	2011-09-04	2017-10-11	株式会社糖鎖工学研究所	糖鎖付加ポリペプチドおよび当該ポリペプチドを含む医薬組成物
AR088392A1 (es)	2011-10-18	2014-05-28	Aileron Therapeutics Inc	Macrociclos peptidomimeticos
CA2862038C (en)	2012-02-15	2021-05-25	Aileron Therapeutics, Inc.	Peptidomimetic macrocycles
HK1205454A1 (en)	2012-02-15	2015-12-18	Aileron Therapeutics, Inc.	Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
BR112015009470A2 (pt)	2012-11-01	2019-12-17	Aileron Therapeutics Inc	aminoácidos dissubstituídos e seus métodos de preparação e uso
EP3007704B1 (en) *	2013-06-13	2021-01-06	Antisense Therapeutics Ltd	Combination therapy for acromegaly
CN103467575B (zh) *	2013-08-22	2016-03-02	深圳翰宇药业股份有限公司	一种帕西瑞肽的制备方法
CN103641894B (zh) *	2013-12-06	2015-10-28	深圳翰宇药业股份有限公司	一种治疗库欣病的多肽药物的制备方法
WO2016049359A1 (en)	2014-09-24	2016-03-31	Aileron Therapeutics, Inc.	Peptidomimetic macrocycles and uses thereof
CN104447962B (zh) *	2014-12-29	2018-07-17	成都圣诺生物科技股份有限公司	一种合成帕瑞肽的方法
US10253067B2 (en)	2015-03-20	2019-04-09	Aileron Therapeutics, Inc.	Peptidomimetic macrocycles and uses thereof
US20210346527A1 (en) *	2018-09-25	2021-11-11	Advanced Accelerator Applications (Italy) Srl	Combination Therapy
GB201816637D0 (en) *	2018-10-12	2018-11-28	Heptares Therapeutics Ltd	Selective somatostatin receptor agonists
JP2024508880A (ja) *	2021-03-04	2024-02-28	スターゲットファーマリミテッド	コンフォメーション拘束型ソマトスタチン受容体３ペプチドリガンド及びそのコンジュゲート並びにその使用
IT202100032615A1 (it)	2021-12-24	2023-06-24	Italfarmaco Spa	Uso di un agonista della somatostatina nel trattamento di tumori che esprimono SSTR3
CN119708199A (zh) *	2023-09-27	2025-03-28	钱杭江医药科技(嘉兴)有限公司	生长抑素肽类类似物、螯合物及其应用

Family Cites Families (16)

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Publication number	Priority date	Publication date	Assignee	Title
MY147327A (en) *	1995-06-29	2012-11-30	Novartis Ag	Somatostatin peptides
GB0018891D0 (en)	2000-08-01	2000-09-20	Novartis Ag	Organic compounds
US6365380B2 (en) *	2000-02-23	2002-04-02	Pcbu Services, Inc.	Method for stereoselectively inverting a chiral center of a chemical compound using an enzyme and a metal catalyst
EP1482898A1 (en) *	2002-03-12	2004-12-08	The Procter & Gamble Company	Cosmetic composition comprising double coated pigment
GB0206415D0 (en)	2002-03-19	2002-05-01	Glaxo Group Ltd	Deracemisation of amines
GB0300095D0 (en) *	2003-01-03	2003-02-05	Novartis Ag	Organic compounds
PE20050285A1 (es) *	2003-06-24	2005-06-09	Novartis Ag	Composicion farmaceutica que comprende analogos ciclicos de somatostatina
US20060270730A1 (en) *	2003-08-07	2006-11-30	Andreas Katopodis	Histone deacetylase inhibitors as immunosuppressants
GB0318682D0 (en)	2003-08-08	2003-09-10	Novartis Ag	Organic compounds
EP1522311A1 (fr) *	2003-10-10	2005-04-13	Institut National De La Sante Et De La Recherche Medicale (Inserm)	Utilisation de la somatostine ou d'un de ses analogues pour préparer un médicament destiné à réguler la réserve folliculaire ovarienne chez la femme non ménopausée
CA2546448A1 (en) *	2003-11-25	2005-06-16	Novartis Ag	Biomarkers for the efficacy of somatostatin analogue treatment
ITFI20040057A1 (it) *	2004-03-10	2004-06-10	Mauro Giuntini	Analoghi della somatostatina
GB0428151D0 (en)	2004-12-22	2005-01-26	Novartis Ag	Organic compounds
US7824663B2 (en) *	2005-03-10	2010-11-02	Kokyu Alcohol Kogyo Co., Ltd.	Lip gloss composition
PT1787658E (pt) *	2005-11-10	2012-06-22	Chemi Spa	Formulações de libertação sustentada de análogos de somatostatina inibidores da hormona do crescimento
DK2225271T3 (da) *	2007-12-03	2013-10-07	Italfarmaco Spa	Nye ikke-selektive somatostatin-analoger

2008
- 2008-11-24 DK DK08856519.7T patent/DK2225271T3/da active
- 2008-11-24 CN CN200880118937.1A patent/CN101883785B/zh active Active
- 2008-11-24 EP EP08856519.7A patent/EP2225271B1/en active Active
- 2008-11-24 CA CA2702940A patent/CA2702940C/en active Active
- 2008-11-24 WO PCT/EP2008/066081 patent/WO2009071460A2/en not_active Ceased
- 2008-11-24 SI SI200831046T patent/SI2225271T1/sl unknown
- 2008-11-24 PT PT88565197T patent/PT2225271E/pt unknown
- 2008-11-24 JP JP2010535349A patent/JP5331817B2/ja active Active
- 2008-11-24 HR HRP20130948AT patent/HRP20130948T1/hr unknown
- 2008-11-24 KR KR1020107010880A patent/KR101500528B1/ko active Active
- 2008-11-24 BR BRPI0818978A patent/BRPI0818978B8/pt active IP Right Grant
- 2008-11-24 PL PL08856519T patent/PL2225271T3/pl unknown
- 2008-11-24 US US12/734,475 patent/US8937152B2/en active Active
- 2008-11-24 ES ES08856519T patent/ES2431573T3/es active Active
2013
- 2013-10-10 CY CY20131100895T patent/CY1114490T1/el unknown

Also Published As

Publication number	Publication date
KR20100103464A (ko)	2010-09-27
US8937152B2 (en)	2015-01-20
PT2225271E (pt)	2013-09-27
WO2009071460A2 (en)	2009-06-11
EP2225271A2 (en)	2010-09-08
KR101500528B1 (ko)	2015-03-09
HRP20130948T1 (hr)	2013-11-08
DK2225271T3 (da)	2013-10-07
CY1114490T1 (el)	2016-10-05
BRPI0818978B8 (pt)	2021-05-25
CA2702940C (en)	2016-09-13
JP2011505345A (ja)	2011-02-24
EP2225271B1 (en)	2013-07-31
BRPI0818978A2 (pt)	2016-05-03
CN101883785A (zh)	2010-11-10
JP5331817B2 (ja)	2013-10-30
ES2431573T3 (es)	2013-11-27
CN101883785B (zh)	2014-01-15
CA2702940A1 (en)	2009-06-11
SI2225271T1 (sl)	2013-10-30
BRPI0818978B1 (pt)	2019-09-10
US20100323964A1 (en)	2010-12-23
WO2009071460A3 (en)	2009-12-17

Publication	Publication Date	Title
SI2225271T1 (sl)	2013-10-30	Novi selektivni analogi somatostatina
IL213479A0 (en)	2011-07-31	Glucagon analogues
IL213478A0 (en)	2011-07-31	Glucagon analogues
IL213477A0 (en)	2011-07-31	Glucagon analogues
IL213480A0 (en)	2011-07-31	Glucagon analogues
IL195730A0 (en)	2009-09-01	New pyridine analogues
IL202550A0 (en)	2010-06-30	Heteroaryl amide analogues
IL204066A (en)	2015-06-30	קומפלקסים של peg שיוצרו באמצעות שיטת dnl ושימושיהן
IL209382A0 (en)	2011-01-31	Water-soluble acetaminophen analogs
IL195980A0 (en)	2009-09-01	New pyridine analogues
ZA201006733B (en)	2011-06-29	Oxytocin analogues
ZA200906812B (en)	2010-12-29	Crig antagonists
IL195981A0 (en)	2009-09-01	New pyridine analogues
ZA200810647B (en)	2009-12-30	New pyridine analogues
EP1841430A4 (en)	2009-07-29	SUBSTITUTED PYRIDAZINYL AND PYRIMIDINYL-CHINOLIN-4-YLAMINE ANALOGUE
EP2285379A4 (en)	2011-11-02	ANALOGUES OF 1-METHYLNICOTINAMIDE
IL195982A0 (en)	2009-09-01	New pyridine analogues
EP2197879A4 (en)	2012-02-15	CAMPTOTHECIN ANALOGUES SUBSTITUTED IN C7
EP2197279A4 (en)	2010-10-13	C10-SUBSTITUTED CAMPTOTHECIN ANALOG
GB0710295D0 (en)	2007-07-11	Handrails
GB0723556D0 (en)	2008-01-09	Handrail
BRPI0920777A2 (pt)	2016-03-08	análogos de somatostatina
GB0808400D0 (en)	2008-06-18	Somatostatin
GB0711673D0 (en)	2007-07-25	Glucagon analogues
ZA200810422B (en)	2010-01-27	New pyridine analogues